Coregonus clupeaformis (lake whitefish): 121547101 Help Entry 121547101         CDS       T08357                                  Name (RefSeq) dystonin   KO K10382   dystonin Organism cclu  Coregonus clupeaformis (lake whitefish) Pathway cclu04382   Cornified envelope formation Brite KEGG Orthology (KO) [BR:cclu00001]  09150 Organismal Systems   09158 Development and regeneration    04382 Cornified envelope formation     121547101  09180 Brite Hierarchies   09183 Protein families: signaling and cellular processes    04812 Cytoskeleton proteins [BR:cclu04812]     121547101 Cytoskeleton proteins [BR:cclu04812]  Eukaryotic cytoskeleton proteins   Intermediate filaments    Intermediate filament-binding proteins     121547101 BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  Spectrin Plectin SR_plectin_7 CH Spectrin_2 GAS2 Spectrin_3 SH3_10 Spectrin_SYNE1 EF-hand_1 EF-hand_7 EF-hand_6 Spectrin_4 EF-hand_5 DUF1664 Spectrin_1st_PEPL Motif Other DBs NCBI-GeneID:  121547101 NCBI-ProteinID:  XP_041714145 LinkDB All DBs Position 31:36620097..36818273 Genome browser AA seq 8122 aa AA seqDB search MIAAAFLVLLRPYSIQVVLLLLLLLLGTIATILFFCCWHRRLRNGKHPIKSVLSGRSRSR AGLRTHHFRSEGFRHSPRHARRARARVAEEKPLVEIPQSDHQSDSSTTVRKRKVKKRVLP DFYHSVQVTPTRKPSSGSGNASLHCSMSSSADFSDEDDYSLKSGSVSPAPGDTLPWNLPR HERHKRQIQGGSVLDPAERAVLRIADERDRVQKKTFTKWINQHLLKVRKHVNDLYEDLRD GHNLISLLEVLTGQSLPRERDFLKTLRLVSSAEACAVEQHGDAQDDDKGPREKGRMRFHR LQNVQIALDFLRRRQVKLVNIRNDDITDGNPKLTLGLIWTIILHFQISEIHVCGESEDMT AKERLLMWSQQMTEGYVGVRCDNFTTSWRDGRLFNAIIHKYRPDLVDMAGVSAQTSRSNL EQAFGVAERLGVARLLDPEDVDVQTPDEKSVITYVSTLYDVFPKVPDGVDGINANDVDIK WVEYQNMVNYLSQWLKHNVAVMSDRAFPNNPVELKALYTQYLQFKENEIPLKETEKSKIK HLYKMLEVWIEFGRIQLPQGYHPNDVEKEWGKLIVAMLEREKSLRPEVDRLEMLQQIATR VQRDCVTGEDKLALARAALQSDAKRLESGVQFQNEAETAGHLLECENLLRQQVVDIQILL DGKYYYSDQLVQRVSKLRDDLLGLRAECSSVYSQGRTLTTEQTKMMISGITQSLNSGFSS SNLNSSLTPALTPGGLGTPGSTFTSILTPGLTPALSPALTPGGMQPGSVQAYMGGGGMDP GDLQHLKQMQIRKPLGKSSLVDPNMTEDEVNMNFVQDLINWVEEMQVQLDRGDWGSDLPS VETHLENHKEVHRTIEEFQMSLKEAKLSEIQMTQKLGYSEKLDKLETQYGKLLNCSRERQ KNLESLHDFVSRATMELIWLNEKEEEEVAFDWSDRNGNISKKTEYHADLMRELDEKEEVI KSVQDRAENLLQENHPARLTIEAYKAAMQTQWSWILQLCSCVEQHLKDNTVYFEFFNDAK ESTDYLKSLQGDIQRKYGCDRTSSVHKLEDHIQESMDEKEQLLQYRSTVAGLVGKAKAIV QLKPRNPDTPVRSSIPVKAICDYRQIEITIYKDDECVLASNSHRAKWKVISPSGNEAMVP SVCFTVPPPNKEAVDQASRIEQLYQNVLALWHHSHIKMKSVVSWHYLMADVRAIRNWNVS SIKTMLPGEHQQVLSNLQSHFEDFLEDSKESEVFTVADCSQLEREVLACKDYYEELLKSA EREEHEESVYNLYISEVRNFRMRLEAQEEHLIRQIRTPLDRDDLEQSVLRITEQEKKKAE LDQLKEDLETVKEKCEMFLRQAGASPAVPTLSSDLNVLIQSMSQVYSMSAIYLEKLKTVS LVVRHSQSAEALVKLYEAKLSEEDAVNSDLSSIDTVVSTLKQWRSEIDEQREIFHDLEDG LQKARGISERMFKAHNERDFDLDWHKEKADQLEERWNNVHSQIESRLRDLEGISKSLKYY KDSYSSLDEWVREMEAAQLKTQEKQPEDSKALAELVNQQKVLVAEMEHKQSRIDECQKYS EQYSSGAKDYELQLLTYRAMVDSQHKSPLKRRRMQNSADAIIQEFMELRTRYTAVVTSMT QYVKFASETLKRTEGEEKRKASERTEYLTWTESWELQKAAGEEVIGKLQQQRSVDEEKKE HGDKVSKLLGWMSSVKPGQNKDGKASTEASSKPQVSMEEMVTKKEQIAEALRTTQLMLTK HSDKMTEEEKQEAKEQLKSLHQAYSDLSQQCSDQTPSAEQEFQTIEGVLEVGSIEVYSVF SSVQSGLIDHTTGLSLLEAQLVTSGLVLPQFRMCLELDDAFHHNLIDEATWKQLRELKEA NQNILSPPFSSEPLPVMAALREGAVSERLAMKVIEIQLATGGLRVSYTGDVLTLERAFQF GLIPAPLYVKLLERQNTWKDLINPGTAEKVSLTQLVQRSVVDEETGLRLLPVKKSHNGSI ELTSGREMSVLRAVHEGLIDRETTLRLLGAQLFAGGIADPKTGRKLTVEQALSEGLIDQD TASGILSQQAQNGGIVNPQNGKRLTVDEAVQCDLISFSSALLVLEKQKGLMGLLWPHSGE ILSVSTSLRHEIITYQLAFKLLSNRQKIAALYIPEYSEVVDINSATQNGFIDAHTAEVLK TIEIPDVFPDVVELNERFSNWLMLRELQIGGSHRPTDDNEIDDENINTPSPIEAKQLFIS YLTLNSYMDPKSGQRLLIFDGQLTKMAELLVDISVETTENQVYNTGPGEATFGDISLKEN ISEDSEMSFESNTEDFGYLHINEETDGTMKDHRASNFFREEESDYNQSDNKTFFNNVVKM VAQHGTEESASAIDSVKNTTQPDSEISIYQKNTSSISLAPIAIDAESSDNQPKETFNGSS ATQTPPTDMSLPSGAQDCKRMLAQDFTEELSSAVKNTRQHDSDTSVLSDGPPPCEIGLET SDMALYNQPIGESDTQAMSKSSAPTKSCSVNGKDMSLLAQCVTEEASVAVHSEKIARQPD SKANVLSKSIYQKTRHGTSPSSFEIGVETSEIPSDHQPQETVNGVSASQTVLEISAPPGL CLVNDTDMHLSSGAKDSKKVVAQGLTEEASVEVSSCKNTSTSPALIEIDLVTTETSSDNQ PKDTANGGSATQTILEISTPPRSLSVDSEKTIRQPDSEAKVSKKKINNTSLGPFEIDVET SQIASDNQPQETFTFNEGSARQIILERSTHPILCSVNDTDTSFPSAAPDSKRMPAQEEYS SYENNAQHSKREVAHGFTDESSISVDSENNTRQPSFEMGVVSDRIYQTNTMSTIPTPFKM DSETDIASDNQPKVTFKGSSATQTVLKSSTLCSGKDTGLSLASVAQGSPQRPTYPVTPGC ETDKDTNFESSLLATDTLDTTTAFPCTEEVVWDNEDERVLASHLLRAQVEEGGILDIISG KRYDLDAALGKGHVDKETVLEVLELQLHKGDVLGEERSTMATLKEAVSKGPISSQMALQI MEQHSLLGGAYESKSGCTISVSEALDSGMIDDDLAVKILQLDPVHKAIVDPDRHCTHSIS YSRSLGLIDNDEAENIRQHQKDKKLAVLVLDDPDEEEGIENRNRHAGEDLDAEGNREQNC DSQKSLLPSFTISHRPVCRQIISPILSDQLTGGRVIHQLDTTSSLREDGASQAPISPLSD MVPGSRNSIQNYMSSNRSNSLSLSDSGDSGAPQRQAEELRQTEEDSSSSLRRETDLSCEA VGFTPHDGQLGAGYHEIVGDQTVCPVQSDSGVSCSSHSDLLSDEKKMENVLNAVQPPASQ LLKESDRRIDSSSPRDLSGDVTSTVSRVVGVNGDKTVINGDEVSSFSTVSPQQPLVKSER NIGGDIKPTSSQNEHSQSKPTGQKKSPVQLTNSSDLAIVSNVLSVETGSDNKDSYDIGDQ EQLQTAPTKEIFSTITPDPTLTDKHLPNSNSNVKAKANDRVESSRSGDSKPGRQEGSSNG GLSQITDQADSATVSETSQTGQTSSDKRNSGVSEKLPDTSSSSASEMTPGNPLKAKEPGM RSDVKQDECGSFENNPQPMAVNAQPDSHSNTPSTSEITSGHPVKPGLGSDLTCDGCRQNQ CCADENHPHLMTVDVPPDSMTPDSVPPPVSAIYTALRSGLDELVRMRVEGADVDDVQKAE TQAVEDIINLIQDNPQSHGRGFGDFGEETDAASGLMKSSSPDLLRDLLKQEAFRSGKTSP VEEEGEPPHEETTPSDMTQIQSRLLQVLQSVSSSQDPAVLRDVIGTLCSILDGAPHEDRP HNLEIIQEEGLSDEAEGALADPMEAPDLFQSTEVETISDTGNADAVQSKVRQQYSTQDYL ECVGRLQDHADVLEEIRNDLSSQQGSLSNSMEELHIQLDESQSLEAHLSTLASFLTRDLN ITKQLLKSANELVPTHIHQDLASAFLELQPFFADVRQMSAERNDVLRQAIDTGKAQLEST YQDLLSTLDRLSGCIHENSEMACNLDILNTSDTDTVKDMIQKNKGMETNLSGTQRHLEDT AFDIQYFISEHAQFLSPAQSKHLLKSLSATQRAFKEQTESVANKRRTLELHLEIREDESQ QKYMVEKQKVFSDKLQELCDNLTNTENRLIGHQQQTKGAESVEDLQQVHQEHQALQKDIL TNGSALNEVISSTNKFLDENRSKLTPDQIVAIESKLEDANSKVKLINQRAEESRKDLEKS MTTAIKQETEKEAAVEQLEESKNKIEGLLDWINNMGNEKGMGGDQTDHMGGDQTDHIGIL NGNMPLQSETSAKNILGEDDDPNGNNGNAFQTTDNDTEGQATGKTPELDLEKQYDRVKAR HQEILSQQKDMIMATQSAQALLDHQAHALSPTDKDKLQRDIQELKGRYDASLTQAEQQMK QVVQVQEELKKFQGDCEEFEGWLQQAEGEVGELGSPAGALNVLTEKLQRQKSFSEDVISH KGDLRFITISGQKVLDVAKACGRMDPGGKDAQLDVDTTGTCAAVKEKLDSAAGRFKALHS QCNELGNNLRDVVDKYKKYEDSTAGLLKWLNNSEDEARRQQSEAIAADPQTLQKQLEDTK ALQGQTAGRQTAVETLRKTADSLVTAEGDLLTNQDVIQERVDDIVERYDNLSKSVSDRNE KLQITLTRSLSVQDGLDEMMSWMEGVEKSVKEKGQVPLDSAAIGDVLSKEAALEQDISSR QSSISAMKAKVKKFVETADPAAAALLQSKMDGLSQRFSDACDKHKQKVGQLEQLKDKVEE FEKTSEKVQQFVLKRSQALSETDGPGKNVNELSQLMQYTNTELAEHAKDVEMLQTLSKEL ANMGPEGSNAQIQSKMDNVSNTFNAFKNTVKEKEEEVSSCQDQLGDFMAAAGDIRTWLEE TTEKVPVVQPTISEQSLAKDLQRVNALMEEWTTKGSAVQDINSKGSALCSLISVLTSPAK IKMSHKSAVTNSGGPGNHAYLTNKELMVVQQNMSYINEGHESLGKLLKGRAAELSGLVQE VTEAQKETDTMITWLKDMKKTAASWNSASTEKDAMKTQLEQQKAFEEDMKQKREQLQKLR EKLLHLIEKHPDSPEAAKWKQMLSQIDDAWVDVSESVEDRKQHLEESNRNLDVFQTTEQQ LRQWLSEKDMMLSVLGPLSMDPNMLNTQKQQVQILLNEFDSRKPQFDQLNEAAAAILSTS GKHDPSSGGKVVKNQLAAVTQKWQGLTGQLGQRAGLIDQAVGKSGQFQDLLRSLSQSTAS LETRLNSQQALSSQPDVLKKQLEEANTISGQLREERKRLNEAETLCSELSALVTEDYLKA GLVMQLEGVTKPFKQLEDKAGKRIQQLNSAFASSQQFHQTSKDFQGWMNEKLQEQSKPQA ISAQMETLRQSLKEHSALQKALSEHEEPYSTIVREGETLLQNTDGAEKVAMQGQLAALRS NWDDVKKSSAERQDKLQGALQRAQKYHEHAEKLQSWVQECEVREGSVRLSVDPAEVESSI SQLKAIQKDVEKHRGLVEQLNTVADSLLEVANADTEAIREEKVAIGQSVDRVTEGVQNKR ESLEKISQRLKEFNDTHKEAKGQLEGAKKQLDAHTSLGVQAYSNKNLTNMKAQQKSLDGV NTQVEHLKSLAQGLVADVPEADGVTDLLLQADSLEKEHGSLSKDVGETCSTLEGKLQGIG QFQTNIRKMFTRFADLDDELDSMASVGRDLATLKEQQGGIKGFVEKLQELMADTARGGDS CKKMLVTEASPDLLGLKRDLDALSKQCGKLMDRAKGREEQVGSTLTRLDELYSKLQQFTN KLSEAEVKEEGQGSVGMETDVINQQLEAFKVFQQEVDPLQSQLQDINWLGQGLIQNAAKG TSTKGLEHDLEDVNTRWNTLNKKIAERSVQLHEALLHCGRFQDALESLLSWLTDTEDLVS NQKPPSAEFKVVKAQIQEQILLQRLLDDRRPTVELIKKEGGKVAELGAESVDKEKVGKEI ECLGQRWDALLKKAENRHKQLKSILVVAQQFHETLEPLSEWLSATEKCLAKAEPIGTQTS KLEEQISQHKVLEEEIMTHSKDLVQAVSLGQMLKLVSSVDDKELVQSKLDSSQASYVELQ ERCRRKAKMLQQALANAQLFGEDEVALMNWLNEVHTRLSEVSVKDYKTDVLEKQCAEQLA LHEDIELRKQNVDQAIANGLELLKQTTGDEVVVIQGKLDGIKTRYAEINSMSDNVSKTLD QALTLASKLQHTHEDLNSWLKNVEAELTAFAAQEPVGEQLIQAQDRQKALLKEARDHKPQ VDKLNEVSSSLLELVPWRAREGLDKLVTEDNDRYKATSDTIAHHVEQIDAAILKSQQFEQ AADTELAWLTEAERKMLSLGEIRLEQDQTTVQLQAQKGFSMDVMRHKDAVDGIVKTGQAI MNSKDEEEKQALKAKIQALLEKYAVVSQMNSERCLQLERAQSLASQFWETYEELWPWLQE TRTSFSQLPLASIEYEALRQQQEELRQMRELIAEHKPYIDKMNKTGPQLLELSPVAGVPI REKYTATDQLYAQLKADVKQRAFTLDEAISKSTQFHDKIEPMLESLERIAERLRQPPSIS VEVEKIREQITENKVVSADLEKLQPSYDTLKQRGEEMIARSAGADKDVSAKAVQDKLDQM VFTWNEIHALMEEREAKLLDVMDLADKFWCDHCALIVTIKDTQDLLRELEEPGVDPSVVK QQQEYLESFKEEIDGLQEELDVVRNLGAELMAACGEPDKPVTKKSIDEVNSAWETLNKAW KERVDRLDEAMQAAVQFQDGLQGMFDWVDIVEHKLGSMSPVGTDLDTVKQQIEELKEFKG EAYQLQMEMERLNHQAGLLLKKVTEEYDRCAIQEPMTELKMLWDNLDEKIINRQHKLEGA LLALGQFQHALDELLAWMSNTEELLNEQKKAVGDPKAIEIKLAKHHVLQNDVLAHKTTVE AVNKAGTDLVESTSGEEAAGLQSKLENLTQRWKNILEKTEQRRHQLDSALLQAQGFHGEI EDMQQWLKDTERQLLASKAVGGLPDTAREQLNAHLELCSTLEAREELYQQLMNKGQQLLT MTPFGQESNTEQDLRNLQDKWESVQVKAAERKVKLEEALALATEFHNSLQDFINWLTQAE QTLTMSSPASLILETILFQIDEHKVFVTEVNSHRQQIIELDKTGTHLKYFSQKQDVVLIK NLLISVQGRWEKVVQRSVERGRLLDDARKRAKQFHETWNKLTEWLDDSEKALDSELEIAN DPDKIKTQLAQHKEFQKVLGSKHSVYDTTSRTGRALKDKTSLQDDNQKLDDMLSELRDKW DTVCGKSVERQNKLEEALLFSGQFTDALQALIDWLYRVEPQLAEDQPVHGDIDLVLNLID SHKVFQKELGKRTGSVAALKRSAKDLIESSHEDSSWVKAQMQELSARWETVCARSVSKQT RLEQALGQAEEFHSTVHMLLEWLAEAEQSLRFHGTLPEDEEALRALIEQHKEFMKKQEEK RVGLNKATSMGEVILTICHPDSITTIKHWNTIIKARFEEVQAWARQHQQRLAMALSDLLA TKELLEGLLGWLQWAETTLNDKDKEVLPQEIDEVKALIAEHQTFMEEMTRKQPDVDKITK THKRKAAVGSEPASQSQIPVLEKGRGGRKRSPTQAMYPSSSQPPIETKNPRVNLLVSKWQ QVWLLALDRRRKLNDSMDRLEELKEFANFDFDVWRKRYMRWMNHKKSRVMDFFRRIDKDQ DGKVTRQEFIEGILSSKFPTSRLEMSAVADIFDRDGDGYIDYYEFVAALHPNKEAYKPLT DADKIEDEVTRQVAKCKCPKRFQVEQIGANKYRFYLGNQFGLVHCLHDHEIITSRDSENL TPHLHLAVLESCILFGDSQQLRLVRILRSTVMVRVGGGWMALDEFLVKNDPCRVHHHGSK MLRSESNSSITQSPIGWQQISHFLTLLHEPPSAKGRTNMELREKFILPEGTTQVMASFRY RGRRSRPSSRAASPNRSNSNHSCPGQHNNPALPSTPKTPQHITRNYDKPWLTNSKPSTPL KSSDSFESQGSSSESTPIQGSKLRLPGYLSGKGFQSGEEQGTLINAAVMKARGQAIGFES RRPGSRPGSKAGSRGSSRRGSDASDFDISDIASVCSDMSEMVGDTSRATPRSSSRQHGGK PTKIPTPQRRSTPSKLAKTSKR NT seq 24369 nt NT seq  +upstreamnt  +downstreamnt atgattgctgcggcgtttttggtcttattgagaccgtatagtattcaagttgttttgcta ttattgctgctattgctaggaactattgcaacaattctttttttctgttgctggcatcgg aggcttcgtaacgggaaacatcctataaaatctgtgctttcagggcgctcaaggagtcgc gctggtctccggactcatcattttcgatcagagggtttcaggcacagtccgcgccatgcc aggagggcacgcgctcgagtggcagaggaaaagcctcttgtcgaaattccccagagtgat catcagagtgactcgtccacaactgtgaggaaacgaaaagtgaagaaaagagtccttcca gatttctatcactcagtacaagtcaccccaacacgaaaacccagctccggttctggcaac gcttcccttcactgttccatgtcttcatcggcggatttctcggacgaagatgattatagt cttaaatctgggtcggtctcaccggcaccgggggacacgttaccctggaacctacccaga cacgagcgacataagcgacaaattcagggaggatccgttttggatccagcagagagagcg gtgctcaggattgcagatgaaagagacagagtgcagaaaaagacttttacaaaatggata aaccaacatctcctgaaggtacgaaagcatgtaaatgacctgtatgaagacctacgagat ggacataacctgatctcactgctggaggtcctgactggccagtcattgccaagggagcgt gatttcctcaagacattgcggttggtgagttcggcagaagcatgtgcggttgagcagcat ggagatgcgcaggatgatgataaggggcctcgggagaaagggaggatgcggttccataga ctccagaatgtacagatagcactggacttcttaaggaggcggcaggtcaagctggttaac atccggaatgatgacatcacagatgggaatcccaaattgacgctgggattgatatggacc ataattctgcattttcagatctcggagatccatgtttgcggggagtcggaggacatgaca gccaaggagcgtctgctgatgtggtcccagcagatgaccgagggctacgtcggcgtacgc tgtgacaacttcaccacctcctggagggacgggaggctgttcaacgctatcattcacaaa tacaggcctgacctggtggatatggccggagtgtcggcccagactagccggtcaaactta gaacaggcctttggtgtggctgaacggcttggggtggccagactactggaccctgaggat gtggatgtgcagactcctgatgagaagtcggtcatcacatacgtctccacactgtatgat gtcttccctaaagtacctgatggtgttgacggtatcaatgcaaatgatgttgatataaaa tgggtagagtaccagaacatggtgaattatctgagccagtggctcaaacacaacgtggca gtgatgtcagacagagcgttccctaacaacccagtggaactcaaggcactttatacacag tacttgcagtttaaagagaatgaaatcccgctgaaagaaactgagaagagcaaaatcaag catctttacaaaatgctcgaggtgtggatcgagtttggtcgtatccagctacctcaggga tatcaccccaacgatgtggagaaggaatggggcaaactgatcgtggccatgctggagaga gagaagagcctgaggcctgaggtggacaggcttgaaatgttgcagcagattgccaccagg gtccagcgggactgtgtcacaggagaggacaaactagcattagcaagagcagctctgcag tctgatgctaagaggttagagtctggggtccagttccagaatgaggcagagactgctggg caccttctggaatgtgaaaacctgctgagacagcaggtggtggatatccagattctactg gacgggaagtactactactctgatcagcttgttcaaagggtatccaagcttcgtgacgac ctgctgggcctgagggcagagtgttcctctgtgtacagccaaggacgcaccctgacaacc gaacagaccaagatgatgatctcaggcatcactcagagtcttaactcaggcttctcctcc tcgaacctcaattccagcctcaccccagccctcacccctggaggcctgggaacccccggt tccaccttcacctccatcctgaccccgggcctcacccctgccctgagccccgccttgacc cccggcggcatgcagcccggctcggtgcaggcctacatggggggcggaggtatggacccg ggggacctccagcacctcaaacaaatgcagatccgcaagcccctgggcaagtcctcgcta gtggaccccaacatgaccgaggatgaggtcaacatgaactttgtgcaggacctgatcaac tgggtggaggagatgcaggtgcagttggatcgtggagattgggggtccgatttgccaagt gtggaaacacatttagagaaccacaaagaggttcacagaaccatcgaagaatttcaaatg agccttaaagaagccaaacttagtgagattcagatgacccaaaaactaggttattctgag aaactggacaaattagaaacccagtatgggaagttactgaactgttcgcgggagcgtcag aagaacctggagagcctccatgactttgtgtcgcgagccaccatggaactcatctggctc aatgagaaagaggaggaggaggtcgccttcgactggagcgatcgcaacggcaacatctcc aagaagacagagtaccacgctgatctgatgagagagttggatgaaaaggaggaggtgatc aagtctgtacaggacagggcagagaaccttctgcaggagaaccaccctgccaggttaact attgaagcatacaaagcagccatgcagacccagtggagttggatcctacagctctgctct tgtgtggagcagcacctcaaagacaacacagtctattttgagtttttcaatgatgccaaa gagtccacggattacctgaagagcctacaaggtgacatccaaagaaagtatggctgtgat cggacaagcagcgtacacaagctggaggatcacattcaggagtccatggatgagaaggaa cagctcctccagtaccgcagcacagtggctgggttggtgggcaaggccaaggccatcgtc cagctcaagcctaggaacccagatacccctgtcaggtcttccatacccgtcaaagccatc tgtgactaccgacaaatagagatcaccatctataaagatgacgagtgtgtcctggccagt aactctcaccgggccaagtggaaggtgatcagtccgtctgggaacgaggccatggtaccc tctgtctgcttcaccgtgcctccacccaacaaggaggctgtggaccaggccagcagaatt gagcagctgtaccagaatgtcctggctctgtggcaccactcccacatcaaaatgaagagc gtggtctcctggcactacctaatggctgacgtcagagccatccgcaactggaacgtttcc tcaattaagaccatgttgccaggcgagcaccagcaggtccttagcaacctgcagtcccac tttgaggacttcctggaggacagcaaggagtcagaggtgttcactgtggcagactgttcc cagctagagagagaggtgctggcctgcaaggactactacgaggagctgctcaagtctgca gagagagaggaacacgaggagtctgtgtacaacctgtatatctctgaggtgcgtaacttc cgcatgcgtctggaagcccaagaggagcacttaatccgacagatccgcaccccactggac agagacgacctggagcaaagtgtcctgcgcatcacagagcaagagaagaagaaggcagag ctggaccagctgaaggaggatctggagaccgtgaaggagaagtgtgagatgttcctcaga caggccggggcctctcccgctgtccccaccctctcctctgacctcaacgtcctcatccaa agcatgagccaagtctactccatgtctgccatctaccttgagaagctgaagacagtgagc ttggtggtgaggcacagccagagtgcggaggctctagtgaagctctatgaggccaaactc tctgaggaagacgccgtgaactctgacctgagttccatcgacacagtcgtcagcacactc aagcaatggcgctcagagatcgacgaacagagggagatcttccatgacctggaggatggg ctgcagaaggcccgtggcatcagcgaacgcatgttcaaggcccacaatgagcgggacttt gacctggactggcacaaggagaaggctgaccagctggaagaaaggtggaacaacgtccac tcccagattgagagcagacttcgggacctggagggcatcagtaaatctctgaagtactac aaagactcctacagcagtctggatgagtgggtcagagaaatggaggctgctcagctcaag acccaggagaagcagccagaggacagcaaggcgctcgctgagctggtaaaccaacagaag gtcctcgttgcagaaatggaacataagcagagcagaattgatgaatgccaaaagtactcc gagcagtactcatctggcgctaaagattatgagctacagctgttgacctacagagccatg gttgactcccagcacaagtccccgctcaagagacggaggatgcagaactcggctgatgct atcattcaggagttcatggagctcagaactcgctacacggccgtagtcacctccatgacg cagtatgtaaagtttgcaagtgagacgttgaagagaacagaaggcgaagagaaaaggaaa gcatcagaaagaacagagtacctcacctggacagagagctgggagctccaaaaggcagca ggggaggaggtgattggaaagctccagcagcagagatctgttgatgaggagaagaaagag catggtgataaagttagcaagctattgggttggatgtccagtgtgaaaccaggccagaac aaagatggtaaagccagcacagaggcctctagtaagcctcaggtttcaatggaagagatg gtaacaaaaaaagagcaaattgcagaagcactgaggacaacacagttgatgctaactaaa cacagtgataagatgaccgaggaagagaagcaggaagccaaggagcagctgaaatccctc catcaagcctacagtgatctctcccagcagtgttctgatcagacaccgtctgccgagcag gagtttcagaccattgagggcgttctcgaagtgggaagtatagaggtctactctgtgttt agctctgtccaaagcggcctgatcgaccataccactgggctcagtctcctggaggctcag ctcgtcacctctggcctcgttctgcctcagttcaggatgtgtctggagctggacgatgct ttccatcacaacctcattgacgaggccacctggaagcagctcagagagctcaaggaagcc aaccagaacatcctgagcccgccattctcttcagaacctctccctgtgatggcagcgctt agagagggggccgtctctgagcgcctggccatgaaggttatagagatccagctggctaca ggtgggttgagggtgtcctacacgggcgatgtactgaccctggagagggcctttcagttt ggcctgatccctgcacctctgtacgtcaagctccttgagagacagaacacatggaaggac ctgatcaaccccggcacggcagagaaggtctcgcttacccagctggtgcagaggagcgtg gtggatgaggagactggactgcgactgctgccggtgaagaagagccacaatgggagcata gagttgacatccgggagggagatgagtgtacttagggcggttcatgaggggttgattgac agagagaccacattgaggctgctgggtgctcagctgtttgcaggcggtatcgccgacccc aaaacaggccgtaagctcaccgtagagcaagccctgtcagagggcttgatcgatcaagac 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cagctggaggaggctaacaccatctctggccagctgagggaggagaggaagaggctgaat gaggctgagactctctgctctgaactttctgccctggtcacggaagactacctgaaagca ggcctagtcatgcagctggagggggtcaccaagcccttcaaacagttggaggacaaagca gggaagcggatccagcaattgaactcggccttcgccagctcccagcagtttcaccagacc tccaaagacttccaggggtggatgaacgagaagctccaggagcagtctaaaccccaggcc atctcagcccagatggagaccctccggcagagcctgaaagagcacagtgccctgcagaag gccctcagtgaacatgaggaaccgtacagcaccatcgtcagggagggagagaccctcctc cagaacacagacggggcagagaaggtggcgatgcagggccagctggccgcactgcgttcc aactgggacgatgtgaagaagagctcggctgagcgccaggataagctccagggggcgctg cagagggcccagaagtatcacgagcacgctgagaagctccagtcctgggtccaggagtgt gaggtcagggagggcagcgtcaggctcagcgtggacccagcggaggtggagagctccatc tcccagctgaaggccatccagaaggacgtggagaaacacagaggcctggtggagcagctg aacactgtagccgacagcctcctggaggtggccaacgcagacacagaggccatcagggag gagaaggtggccatcgggcagagtgtggaccgggtcacggagggggtccagaacaagagg gagtctctggagaagatctcacagaggctgaaggagttcaacgacacccacaaagaggcc aagggccagctggaaggggctaagaagcagctagatgcacacacatcactgggggtccag 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aatcagaaacctccgtctgccgagttcaaagtcgtcaaggcacagatccaggagcagata ctcctccagaggctgcttgatgaccgcaggcccacggtggagctgattaagaaggagggt gggaaggttgcggagctgggagcagagtcggtggacaaggagaaggtggggaaggagatt gagtgcctggggcagaggtgggacgctctgctgaagaaggctgagaacaggcacaaacag ctgaagagcattctggttgtggctcagcagttccatgagacactggagcctctgtctgag tggctctctgccacagagaaatgcttggccaaggctgaacccattggcacacagacctcc aagctggaagagcagatctcccagcacaaggttttagaggaggagataatgactcacagt aaagacctggttcaggccgtcagcctgggtcagatgctaaagctggtcagctcagtggac gataaggagctggtgcagtctaagctggactccagccaggctagttacgtagagcttcag gagcgctgtaggaggaaggctaagatgctgcagcaggctctggccaacgcacagctcttt ggagaagacgaggtggccctcatgaactggctcaacgaagtgcacactaggctgagcgaa gtgtccgtcaaagactacaagacggatgtgctcgaaaagcagtgtgcagaacagctggcc ctacatgaagacattgagttgaggaagcagaatgttgatcaagccattgccaatggattg gagctgctgaaacaaacaacaggtgatgaggtggttgtcatccaaggcaagctggacggg ataaagacgagatacgctgagatcaactccatgagtgataacgtgtctaagaccctggac caggccctgaccctggcctccaagcttcagcacacccatgaagacctcaactcctggctg aagaatgtcgaggctgagctcaccgccttcgctgctcaggagcctgtaggagagcagctc atccaggcacaagacaggcagaaggcgttgctgaaagaggccagggatcacaaaccccag gtggacaaactgaacgaggtgagcagctctctgctggagctggtcccatggagggcccgg gagggcctggacaagctagtgacagaggacaacgatcgctacaaggccaccagcgacacc atcgcacatcacgtggagcagatagatgctgctatactgaaatcacagcagtttgaacaa gcagctgacactgagctagcctggcttactgaagcagagaggaagatgttgtcattgggg gagatcaggctggaacaggaccagaccactgtccagctccaggcccagaagggcttctcc atggacgtcatgagacacaaggatgccgtggatggaattgtgaaaacaggccaggccatc atgaacagcaaggatgaggaggaaaagcaagccttgaaggccaagatccaggccctcctg gagaagtacgctgttgtcagtcagatgaattcggagcgctgcctgcagctggagcgagcc cagtctctggccagccagttctgggagacttacgaggagctgtggccctggctccaggag acccgcaccagcttcagccagcttccactggcgtccatcgagtacgaagctctccgacag cagcaggaggagctcaggcaaatgcgagagctgattgctgagcacaagccctacatcgac aagatgaacaagacaggtccccagctactggagctgagccctgtggcaggggtccctatc agggagaagtacacagccacagatcagctgtacgcccagctcaaggctgacgtcaaacag agggccttcactctggatgaggccatctccaaatccacacagttccatgacaagatcgag cccatgctggagtccctggagcggatcgctgagcgcctgcgtcagcctccctccatctca gtggaggtggagaagatcagggagcagatcacagagaacaaggttgtgtccgcggacctg gagaaattgcagccatcctacgacacgctcaagcagcgcggcgaggagatgatcgcgcgc tcagcgggagctgacaaggacgtatctgctaaagctgtgcaagacaagctggaccagatg gtgttcacctggaatgagatccatgccctgatggaggagagggaggccaagctgctggat gtaatggacctggcagacaagttctggtgtgaccactgtgccctcatcgttaccatcaag gacacccaggacctgctgagggagctggaggagcctggagtcgacccctctgtggtgaaa cagcagcaggagtatctggagagcttcaaggaggagattgacggccttcaggaggagctt gatgtggtgcggaacctgggggcggagcttatggctgcctgtggcgaaccagataagcca gtcacaaagaagagtattgatgaggtgaactcggcgtgggagactctgaacaaggcgtgg aaggagagagtggacagactggatgaggccatgcaggctgctgtgcagttccaggatggc ctgcagggtatgtttgactgggtggacatcgtggagcacaaactgggttctatgtcacct gtgggcacagacctggacactgtcaagcagcagatagaagaactcaaggagttcaaaggt gaggcatatcagctgcagatggagatggagcgacttaaccatcaggcaggcctgctgctg aagaaggtgacggaggagtacgaccgctgtgccatccaggagcccatgaccgagctcaaa atgctctgggacaacctggatgaaaagatcatcaacagacagcacaaactggagggagcg ctgttggctctggggcagttccagcatgcgctggacgagcttctggcctggatgagcaac acagaagagctgctcaacgaacagaagaaggctgtaggagaccccaaagccattgagatc aagctcgccaagcaccacgtcctccagaacgatgtgttggcccataagaccacggtggag gcggtcaacaaggctggtactgacctggtggagtccacctctggagaagaagccgccggc ctgcagagcaaactggagaacctcacccagcgctggaagaatatcctggagaagacagag cagaggaggcaccaactggacagtgctctgcttcaggcccaaggtttccatggcgagatc gaagacatgcagcaatggctgaaagacacagagcgtcagctgttagcatcaaaggctgtg ggcggcttaccagacacggcccgcgagcagcttaatgcccatctggagttatgttccaca ttggaggccagggaggagctgtaccagcagctgatgaacaaaggtcagcagctgctcacc atgacccccttcggccaggagagcaacacagagcaggacctcaggaacctgcaggacaag tgggagtcggtacaggtcaaggcggctgagagaaaggtgaaactggaggaggctttggct ctggccacagagttccataactctctccaggacttcatcaactggttgacccaagctgaa cagactctcactatgtcttctcctgcctccctcatcctggaaaccatcctgtttcagata gatgagcacaaggtgtttgtgacggaggtgaactcccacaggcagcagatcattgagctg gataagacagggacccacctgaagtactttagccagaagcaggacgtggtactgatcaag aacctgctgataagtgtacagggccgctgggagaaggtggtgcagaggtctgtggagagg ggccgtctgctggacgacgccaggaagagggccaaacagttccatgaaacctggaacaag ctgacagaatggttggacgattcggagaaggctttggactcggagctggaaatcgccaat gatcctgacaagatcaagacgcagctggcccagcacaaggagttccagaaggtgctgggg agcaagcactcagtgtatgacaccaccagtcgtaccggacgtgccctcaaggacaagacg tcactgcaggacgataaccagaagctggacgacatgctgagtgaactgagggacaagtgg gacactgtctgtggcaagtcagtggagaggcagaacaagctggaagaggcgttgctgttc tctggtcagttcactgatgccctgcaggccctgattgactggctgtacagagtggagcct cagctggctgaggaccagccagtacatggagatatagacctggtgctcaatcttatcgac agtcacaaggttttccagaaggagctggggaagcggacggggagcgttgcggccctgaag cgttcggctaaggacctgattgagagcagccatgaagactcctcctgggtcaaagctcag atgcaggagctgagcgctcgctgggagacggtttgcgcccgctcagtatctaaacagacc cggctggaacaggcactgggtcaggctgaggagttccactctacagtccatatgctgctg gagtggctggccgaggccgagcagagcctgcgtttccatggcaccctgcccgaagacgag gaggctctcagggctcttatcgagcagcacaaggagttcatgaagaagcaggaggagaag agagtgggcctgaacaaagccaccagcatgggggaggttatcttgaccatctgccatcca gattctatcaccaccatcaaacactggaacaccatcattaaagcccgcttcgaggaggtt caggcgtgggcgcggcagcaccagcagcgcctggccatggccctcagtgatctgctggcc actaaggagctgttggagggtctgctgggctggctgcagtgggctgagaccacactcaac gacaaggataaggaggtcctgcctcaagagatagacgaggtcaaagccctcatcgctgag caccagacattcatggaggaaatgaccaggaagcaaccagatgttgacaagatcacaaag acacacaagagaaaggctgcggtcgggagtgagcctgccagccagtcccaaatccctgtc ctggagaaaggaagaggtggaagaaagcgttctcccacacaagccatgtacccatcatct tcacagcctcccatagagaccaagaaccccagggtcaacctgttggtcagcaagtggcag caggtgtggttactggccctggacaggaggaggaaactcaatgattccatggacagactt gaggagctgaaggaatttgccaactttgactttgatgtgtggcggaaacgctacatgcga tggatgaaccataagaagtcacgtgtcatggacttcttcagacgcattgacaaggatcag gatggaaaggtcaccagacaggaattcatagaaggaatcctgtcctccaaattccccacc agtcggctggagatgagtgcggtggcagacatatttgaccgggatggagacggctatatc gactactacgagtttgtggctgcccttcaccccaacaaagaggcatacaaacccctcaca gatgcagacaaaattgaagatgaggttacacgccaagtggcaaaatgcaagtgtcctaaa cgattccaagttgagcaaattggtgccaacaaatacaggttctaccttggaaaccagttt ggtttggttcactgcttacatgaccatgagattataacaagcagggacagtgaaaatcta accccccacctacaccttgcggttttggaaagctgtattctgttcggagactcccagcag ctgcgtctggtgcggatcctgcggagcactgtgatggtgcgcgtgggtggaggctggatg gctctggatgagttcctggtaaagaatgacccgtgtcgagttcatcaccacgggagtaaa atgttgcgctcggaatcaaactcttcaattactcagtctcctataggttggcaacaaatc tcacactttctcaccttgctccatgaaccccccagtgccaaaggaaggacaaacatggag ctgcgagaaaagttcattctcccagaaggcaccactcaggtgatggccagcttccggtat agaggtcgtaggtcgcggccgtcatcacgggctgcctctcccaacaggtcaaactctaac catagctgtccgggccagcataataacccagccttgcccagcacacccaagactccccaa cacataacccgcaattatgataaaccctggctgacaaacagcaaaccctccactcctctt aaatcatcagactcctttgagagccaaggttcatcctccgagagcaccccgatacaggga agcaaactgcggctccctggatacttgtcaggaaaagggttccagtcgggagaagagcag ggaaccctgatcaatgctgctgtgatgaaagcacgggggcaggcgataggctttgaatcg agacgacccggcagccgacctggaagtaaagcaggtagccgagggagcagccggagggga agtgacgcttcagacttcgacatctccgatatcgcatcggtgtgctccgacatgtcagag atggtgggtgacaccagtcgggccacaccccgctcatcgtcacgtcagcacggaggcaag cccaccaaaatccccactcctcaaaggaggtctacccccagcaaactggccaagacgtcc aagagatag

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