KEGG   Coregonus clupeaformis (lake whitefish): 121552187
Entry
121552187         CDS       T08357                                 
Name
(RefSeq) 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-4-like isoform X2
  KO
K05858  phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
Organism
cclu  Coregonus clupeaformis (lake whitefish)
Pathway
cclu00562  Inositol phosphate metabolism
cclu01100  Metabolic pathways
cclu04020  Calcium signaling pathway
cclu04070  Phosphatidylinositol signaling system
cclu04081  Hormone signaling
cclu04082  Neuroactive ligand signaling
cclu04261  Adrenergic signaling in cardiomyocytes
cclu04270  Vascular smooth muscle contraction
cclu04310  Wnt signaling pathway
cclu04371  Apelin signaling pathway
cclu04540  Gap junction
cclu04621  NOD-like receptor signaling pathway
cclu04912  GnRH signaling pathway
cclu04916  Melanogenesis
Module
cclu_M00130  Inositol phosphate metabolism, PI=> PIP2 => Ins(1,4,5)P3 => Ins(1,3,4,5)P4
Brite
KEGG Orthology (KO) [BR:cclu00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00562 Inositol phosphate metabolism
    121552187
 09130 Environmental Information Processing
  09132 Signal transduction
   04310 Wnt signaling pathway
    121552187
   04371 Apelin signaling pathway
    121552187
   04020 Calcium signaling pathway
    121552187
   04070 Phosphatidylinositol signaling system
    121552187
  09133 Signaling molecules and interaction
   04082 Neuroactive ligand signaling
    121552187
   04081 Hormone signaling
    121552187
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04540 Gap junction
    121552187
 09150 Organismal Systems
  09151 Immune system
   04621 NOD-like receptor signaling pathway
    121552187
  09152 Endocrine system
   04912 GnRH signaling pathway
    121552187
   04916 Melanogenesis
    121552187
  09153 Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    121552187
   04270 Vascular smooth muscle contraction
    121552187
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:cclu04131]
    121552187
Enzymes [BR:cclu01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.4  Phosphoric-diester hydrolases
    3.1.4.11  phosphoinositide phospholipase C
     121552187
Membrane trafficking [BR:cclu04131]
 Exocytosis
  Calcium ion-dependent exocytosis
   Phospholipases
    121552187
 Endocytosis
  Macropinocytosis
   Phospholipase C
    121552187
SSDB
Motif
Pfam: PI-PLC-X PH_14 PI-PLC-Y PLCB1-4-like_EFh EF-hand_like PLC-beta_C C2 EF-hand_7
Other DBs
NCBI-GeneID: 121552187
NCBI-ProteinID: XP_041720843
LinkDB
Position
36:23638555..23766255
AA seq 1228 aa
MTKSYEFNWQKHLPGFMQEGASFDRFDEDPFLFEPNCLVKVDEFGFFITWKSDGKEGQVL
ECSLINSIRVGAVPRDPKILSSFEAVGKKEEELEGSVICICSGTDLVNLSFMYMVADSPD
TARKWTEGLRSVIHNFRANNVCPMTCLKKHWMRMCFLTNVNGKIPVRTITRTFASGKTEK
GIFQALKELGLPSGKNDEIEHSAFPFDIFYALTQKICPRTDIEELFKKINGDKSDFLNVD
QLVSFLNENQRDPRLNEILFPFYEPKRAMQIIEKYERDPDLKKKGRMSSDGFCRYLMSDE
NAPVFLDCLELYQDMEQPLAHYFIASSHNTYLNGRQFGGKSSVEMYRQVLLSGCRCVELD
CWDGKGEDQEPIITHGKAMCTDILFKDVISAIRETAFVTSEYPVILSFENHCSKPQQYKM
ARYCEEIFGDYLLRHPLEGYPVEAGRPLPSPNDLKRKILIKNKRLKPEVEQKQLESFKKH
MEAGETNTPAILLGAETEEDVENALGDVKDVIPDLKTSTSEEPSEENSLSTSVSISDSVS
VNKDREEKERDNSIKKVVEEDPTEMSEATEATDATDISEASEDNNNKKTGETTDDEEALI
ASYTYVGATTNIHPYLSAMVNYAQPVKFQSFDVAEERNIHHNMSSFNESVGLGYLKTNAI
EFVNYNKRQMSRIYPKGGRVDSSNYMPQIFWNAGCQMVSLNYQTPDLAMQLNQGKYEYNG
SCGYLLKPDFMRRSDRMFDPFSETPVDGVIAATCSVQVFSGQFLSDKKIGTYVEVDMYGL
PTDTIRKEFRTRMVMNNGLNPAYNEEPFVFRKVILPDLAVLRIAVYDDNNKLIGQRILPL
EGLQAGYRHISLRNEGNKPLSLPTVFCNIVLKTYVPEGFGAIVDALSDPKKFLSIAEKRA
DQMRALGIETSDIADVPNESSKNDKKGKVNANVKANVTPQTSSDPAQSSKSAQNNTTETK
KDTNTLVPHVNIDDLKQMKTYLKQIKKQQKELNSLKKKHAKDRTIMQKSHCTQVDKMIAQ
HDKEKLTQEKLLEKAIKKRGESNCLELKKETESKVESLTTDHKAKVKDITAQHTKEWSEM
INSHSSVEQDMKDIHVVQQCEHLKKLLSGVQEQQTLSLKLIHERQSKDMRANQAKTSMEN
SKAISQDKTIKNKAERERRVRELNSSNTKKFLEERKRLAMKHQKEMETLEKSQKEQLEEL
DKFNEQAKDIQQMVKLEEEMDRRPATVV
NT seq 3687 nt   +upstreamnt  +downstreamnt
atgactaagtcctatgagtttaactggcagaagcacctgcctggcttcatgcaggaagga
gcttccttcgacaggtttgacgaggatccgtttctgtttgagcccaactgtctggtcaaa
gtggacgagtttggcttcttcatcacgtggaagagcgatggaaaggagggccaggttcta
gaatgttctctgatcaacagtattcgagtcggagccgtgccaagggaccctaagatcctg
tcttcgttcgaggcagtggggaagaaggaggaggagttggaggggagtgtcatctgcatc
tgcagcggcactgacctcgttaacctctccttcatgtacatggtggctgacagtccagat
actgctaggaagtggacggagggtttgaggtcagtgatccacaatttcagagccaataac
gtctgtcctatgacctgcctcaagaaacattggatgaggatgtgctttttgaccaacgtg
aacggcaaaatcccagtgagaaccatcacacggacatttgcatctgggaaaaccgagaaa
ggaatctttcaggctctgaaggaactgggactgcctagtggaaagaacgatgagatagaa
cattcagcgttccccttcgacatcttctatgccctgactcagaagatctgccctcgtact
gacatcgaggaactcttcaagaaaatcaatggggacaaaagtgattttttaaacgtagac
cagttagtcagctttctgaatgaaaaccagcgcgacccgcggctaaacgagatcctgttc
cccttctacgaacctaaacgagccatgcagatcatcgagaagtacgagagagaccccgac
cttaagaagaaaggccgtatgtccagtgatggcttctgcaggtacctgatgtcagatgag
aatgccccggtgttcctggactgcctggagctctaccaggacatggagcagccgctggcc
cactacttcatcgcctcctcccacaacacctacctgaacgggaggcagttcggagggaag
tcctccgtggagatgtacagacaggtgctgctctccggctgcaggtgtgtagagctggac
tgctgggatggtaaaggagaagaccaggagcctattatcactcacgggaaggccatgtgt
actgacatcctcttcaaggacgtgatctcagccatcagggaaacagcctttgtgacgtct
gagtatcctgtgatcctgtcatttgaaaaccactgcagtaaaccccagcagtacaagatg
gctcggtattgtgaggagatctttggagactacctactgaggcatcctctcgagggatac
cctgttgaagcgggccgtcccttgccttctcccaacgacctcaaacgcaaaatcctcatc
aaaaacaaacgcttgaaaccagaggtggaacagaagcagttagagtcctttaagaagcac
atggaggcaggagagaccaacacaccagccatcttactgggagcagagacagaggaagat
gtggagaacgctctaggtgatgtgaaggatgtgattcctgacttgaagaccagtacctca
gaggagcctagtgaagagaacagcctcagcaccagtgttagtatcagtgacagtgtcagt
gtgaacaaagacagagaggagaaggagagggacaacagcatcaaaaaggtggtggaggag
gatccaacagagatgtctgaggccacagaagcaacagacgccacagacatctcggaggct
tctgaggataacaacaacaaaaagactggcgagactacggatgacgaggaggctctgata
gcctcgtacacgtacgtaggagccaccaccaacatccacccctacctctctgccatggtt
aactacgcacagcctgtcaagttccagagcttcgacgtcgcagaagagaggaacattcac
cacaacatgtcgtcatttaacgagtcagtgggtctgggttatctgaagaccaacgccatc
gagtttgtcaactacaacaagcgtcagatgagtcggatctaccctaaaggaggcagggtg
gactccagtaattacatgcctcagatcttctggaacgcaggctgccagatggtctccctt
aactaccagaccccagatctggccatgcagttgaaccagggaaagtatgagtacaatgga
tcctgtgggtatctgttgaagccagacttcatgcgtcgctcagacaggatgtttgacccc
ttctcagagacacctgtggatggggtcattgctgctacctgcagtgtacaggtgttttct
ggtcagttcctgtctgataagaagattgggacctacgtggaggtggacatgtacgggttg
cccacggacaccatccgcaaagagttccgcacgcgtatggtgatgaacaatggcctgaac
cctgcctacaatgaagaacctttcgtcttcaggaaggtgattctaccagacctggctgtg
ctgcgtatagctgtgtatgatgacaataataagctgataggtcagaggatcctaccattg
gagggtctacaggcaggatacagacacatttctctacgcaatgaagggaacaagcctctg
tctttacctactgtcttctgtaacatagtactcaagacctacgtacccgaaggcttcgga
gccatcgtggatgccctgtcagacccaaagaagttcctgtccatagcagagaagagagcg
gaccagatgagagctctggggattgaaacgagtgacatagcagatgtgccaaacgagagt
tcgaagaacgacaagaaagggaaggtgaacgccaacgtgaaggccaacgtcacgccacag
accagctcggacccggctcagtcctctaagtctgcccagaacaacaccacagagaccaag
aaggatacaaataccctcgtgcctcatgtgaacattgatgacttgaaacagatgaagacg
taccttaaacagattaagaagcagcagaaagaactgaactctttaaagaagaagcatgca
aaggaccgcaccatcatgcagaagtcccactgcacccaggtggacaagatgatcgctcag
cacgacaaggagaagctgacacaggagaaactgttggagaaggccatcaagaaacgagga
gaaagcaactgtctggagttgaagaaggagactgagagtaaagtggagagcctgaccact
gaccacaaggctaaggtgaaggatattacagcccagcacactaaggagtggtcagagatg
atcaactcccacagcagtgttgagcaggatatgaaggacatccacgtggtccaacagtgt
gaacacctcaagaaactactgagcggagtccaggaacaacagactctatcgctcaaactg
atccacgaacgccagagcaaggatatgcgggccaaccaggccaagacatccatggagaac
agcaaggccatcagccaggacaagaccatcaagaacaaggccgagagggagaggagagtt
agagagttgaacagcagcaacaccaaaaagttccttgaggagaggaaaaggttggctatg
aagcatcagaaggagatggagacactggagaagtcgcagaaagaacagctagaggaactg
gacaagttcaatgagcaggccaaggacatccagcagatggtgaagctggaggaggagatg
gaccgcagaccagccacagtggtctga

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