Coregonus clupeaformis (lake whitefish): 121577437 Help Entry 121577437         CDS       T08357                                  Name (RefSeq) obscurin   KO K17531   obscurin-RhoGEF [EC:2.7.11.1] Organism cclu  Coregonus clupeaformis (lake whitefish) Pathway cclu04820   Cytoskeleton in muscle cells Brite KEGG Orthology (KO) [BR:cclu00001]  09140 Cellular Processes   09142 Cell motility    04820 Cytoskeleton in muscle cells     121577437  09180 Brite Hierarchies   09181 Protein families: metabolism    01001 Protein kinases [BR:cclu01001]     121577437   09182 Protein families: genetic information processing    04131 Membrane trafficking [BR:cclu04131]     121577437 Enzymes [BR:cclu01000]  2. Transferases   2.7  Transferring phosphorus-containing groups    2.7.11  Protein-serine/threonine kinases     2.7.11.1  non-specific serine/threonine protein kinase      121577437 Protein kinases [BR:cclu01001]  Serine/threonine kinases: CAMK group   Trio family [OT]    121577437 Membrane trafficking [BR:cclu04131]  Others   Rho GTPase associated proteins    Rho guanine nucleotide exchange factors (GEFs)     121577437 BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  I-set Ig_3 ig Ig_2 Pkinase V-set PK_Tyr_Ser-Thr Ig_5 Ig_4 SOS1_NGEF_PH Izumo-Ig RhoGEF V-set_CD47 C2-set_2 PH fn3 IQ_SEC7_PH IQ Kdo RHG20_PH Pox_ser-thr_kin PH_10 APH Motif Other DBs NCBI-GeneID:  121577437 NCBI-ProteinID:  XP_045079316 LinkDB All DBs Position 11:23560448..23622871 Genome browser AA seq 5933 aa AA seqDB search MGHILYKNQTQLLVVKGLEDVEVCESEGCTFEVTLNLSYIDGTWTKDGVRLKSKPTCRIA SHRNKHTLTFTRVTVGDTGLFSFQTDGAQSCIQTSGQLIVIARDIQIMKELDDKEVTERQ SVTFLCEVNYENVDGRWYRDNTRIKHGDNVKIRHEGKTHTMCFKSVRPANAGEIKFTADR VSSYAILTVKELPVQIVKPLRVKIAMYKHKGLLECQVSRANAQVRWFKNRHEIQPSRKHQ IVSDDVYRQLHIDEVVSSDEDTYTCDAHDDKTSCQLLVEEQAISILRGLRSLEVTEPREA LFQVEINLRAGRPPKWTLDGEVLMEGPRVSIDREGTMHTLCFNSTDSSMTGTVQFNAGKS RSTAQLTVKERPLKVVQPMPDVEAKENSSVTLSCQFAPSPRVVRWYRGRTALQTSSKYSM RTEKSQAELTIQGLKESDTGQYSCMAGGSKSTAKVTVEVRRLKIIRHLEHVEVEEDSNAT FTCELNYVVANVQWLLNDKHLNANPVTRIQNMGTIHSLTIKKLCPQESRVTFKAGLLTES TSLKVKEKPAVFLRSLEDMSGEEEGKLCLQCETSKETVTPVWRKDGTVLASSDKYELLKF GKSLALIIHSLSKDDADHYSCDLGTSQTKAKVTVHDLHITIAQRMKTASVLEGESCSFEC VLSHDVIDEPSWTLNGQLVVSNSRFQSVNKGRKYKMTIRDATLTDAGDVVFFIKDLSCRT MLFVREKPVHVFRDMMNVKATPGEDAELSCEITKPEAFIRWLKNGHQIRHSPPKYEINVE DHLVRLVITNTCIRDSGEYCCEADGIATRAKLEVRELQHMFARELREAQAEEKSKVTLEC ETRLPAKRVTWLKGMAELRAGKKYVMKQKGVVLSLTISCLEKGDTDVYTCDVGTMQSRAL LTVHGQKVLIMDELEDVECLENDTVMFRCRICPSDYVGVKWYLDETLLYTNKLNEIQVVP GGYHSLTFKQLARKDSGTISFEAGDKRSYASLLVRERRPTITKTLEDCEAIEGGSLVLVC MTSKPCHILWYKDGCLMWSSSRYYVSRSGNEARLTIREVSNSDAGVYECSAGSVSTKAVV NVKAIPAEFTQPLQNMEVKEGEDVTLWCEFSLPGVAFHWRRGLENLRAGERYLMKQKKSL ISLTITGPKPEDSGDYTCQCRDHRTTATLTVHAIPISFKQQLKNIQAEEGNSFTLRCELS KPGVPVEWKKGEELLRIGVKFQIRKRETISELQIGKAVPEDSGVYSCQCADQKTTATVKI SALPVTFKQKLRNVQVEEGNNLVLHCELSKPGVPVEWIMGGEELLNNGEKFQIKQRELVN ELKILDTKPEDSNIYTCVCGNVETTAGVTVTAIPITFKQKLRNLQTEEGNTISLHCELSK SGVPVEWRLGGEMILQNGDKYQMKQRGLALELVIREPLPEDSGVYSCVCRDQKTKATVKV IAVPATFRVGLKNQEAQEKGSVTLRCELSKSGVPVEWWRGETELSQDLLGGKYQIKLEAR IAEMTITNVQPEDMGKYSCVTGDQKTTAAVKVQALPVTFKRQLQNTMIKEGDSGEFWCEL SKPGAPVDWRKGRVILKSGDKYEMKQEGCITKLLIHDVEESDAGKYTCKTKDAQSTAELT VKGLPPTFKEQLRNMEVEEGKTVTLHCELSKPASSVEWKRGAQLLKNVDKYQMKKKDLLV ELKIIDANLEDSGVYTCICGEQKTTATVTINARPFTFIEELRNVQVEEGNNVTLRCELSK PGMLVEWMRGTDLLRNGEKFQMKQKHATLELIIRKTIPEDSGVYSCVVEDQKTFATILIT AVPVTFKQKLKNQEALEEGSVTLRCELSKSGVSVEWLKGEELLREGERYQMKQEGRTAEM VIRNVVLQDAGEYSCVTACNVKTTADIKVRALPVTFTQEVQNVVIKEGDSGEFWCELSKP GAPVDWRKGRVILKSGDKYEMKQEGRITKLFIHNVEESDAGKYTCKTKDAQSTAELTVKA PPITFKVKLKNQEVEEENSVTLFCELSKPGLMAEWRKGEELLKNGVRYQIKKREATMELT IRKAVLEDTGFYSCVYAEAKTTATVNIIAIPVTFKMGLKNQEAPEGGIVKLCCELSKAGV PVEWWKGEEEVSPGGRYQMKLEGKIAEMHIKNIQPEDVGEYSCIFGDQKTTAEVNVRAAA SVFFEKELESKVVMEGKSVVLSCEVSSVTVPVTWRKDSCLVTDGERFTLKKKGSVHTLEI RMLSLEDAGEYSCITRGKKTTAMLVVKERVKILSGLKDIKIMAGQDAVFVCELSHKEVSE GEWWLGSSPLQKNEMNQMSCLGHQHRLVLTMTTPEETGTVTFVVGEEKTSAQLLVLPKPK VLIEKKPRDIVIMEGETATLSCMTSDLFTPVTWRRNNMPLLNGDKYETRKEGKLNLLLIH ETEPGDSGIYFCDTGDMQSSANLTVNEVPPYFEEELQAVEAEEGGTAFLTCELSKPAVPV QWRKGRLPLRPNRKYQMKQDGCVFQLHILELKKEDGGSYTFQAGGIETTASVSVKVKVLI EKKPRDTVIMEGETATLSCSTSDLVTPVTWKRNRMPLLNGAKYEMRKEGKLNLLLIHETE PGDSGIYSCDTGDMQSSANLTVNEVPPYFEVELQAVEAEEGGTAFLACELSKPAVPVQWR KGRLPLRPNRKYQMKQDGCVFQLHILELKKEDSGSYTCQAGGIETTASVAVKPPSDKADP PKTIPPTKAPTKAPSPTSPPEEAQPGPLERRKRGMTRSSIVESEEDLEPEEKETAVDQQE KQSLRSMGKETKVDQQEKQSFGSMGKETAVDLQEKQSLRSMGKETAVDQQEKQSLRSMGK ETAVDQQEKQSLRSMGKETKVDQQEKQKVKQPVGMVKDNIAENTQKQLVPPLRSKGKEAT MVKETQMDQPEKEPVKQPVRAIVTDTEEKKYMVKKTEIDLLEKKMKEVGVHQVVKQPVPP VRRASIVSDAGIDEMRKQPVPPSRRASVVSVSDAGVDKVRKQPVPPSRRASVVSVSDAGI DEMRKQTVPPSRRASVVSVSDAGVDKVRKQPVPPVRRASVVSVSDAGVDEMRKQPVPPSR RASVVSVSDAGVDEVRKQPVPPVRRASVVSVSDAGIDEMRKQPVPPSRRASVVSVSDAGI DEMRKQPVPPSRRASVVSVSDAGVDKVRKQPVPPVRRASVVSVSDAGVDEVRKQPVPPVR RASVVSVSNAGVDEVRKQPVPPVRRASVVSVSDAGVDEVRKQPVPPVRRASIVSDAGVDK VRNQPVPPVRRASIVSDAGEDKVRNQAVPPARRAPIVSDAGIEQIVRSKKEIDIEVDHQN KQSVKSMVKETDEDHQEKQPVKYMVKETEVDQRDKQPVRFTVQETEKPKIAEDGNQLHIS VGESFTEAPTQVSVNQKTSKPVVAVAGVPKGLQMTKQFDETEPDMEISVEDEPEMLEAAI KIQAAFKGYKTRKDMRPVFKQVFKNQNVETNGTIQLACMVEGKPNAVRWLKNGQQIIGDQ RHRMNTSEDGVCTLVIINMSAIDTGVYTCEVVNKFGVTSYNGNITVGQPQKPPSSTQRPA APAQPSTPSVHPVLASVGPLQPAQTSTSGKETMGSVESEGISLWQAYNLTEEDSRMTLQE RRRASLIAASSMSSPSDYDTAPDFIEPVDIIPKDHPREKEAIKSEDQLQHKVKEQKVTPQ PPKRHLKVKATDAKLRTLSPKHHRAHMSAALTGSGSESDGDEDRKETFAIYVARAKCSSQ HSGNKASFVLKEGQYVEVLDSVHPETWLVRTKPSKNTPSRQGWVSPAYLEKKRTTFPQVR TPQQEMDGSGSTGEEYRRTVSQLIQGLIDGEEEFVKVMKDFTSHYLHHLDTSPDVPINII NQKETIFRNIKDIMALHERSILPRLSECSTDDDVAMHLVKHAEDFEKYLQYMMGQTQAET CVTDKTIQQYFKHNTETEPEHPKTAVLDVITFLQRPVERIQTYQALLKELIKNKAKCGKS CRLLEDAFSMVSCLPWRSDNLHQVSLIENYPAPLTALGEPVRQGSLTVWEESPEIKTSSR WHQRQVFLFKDCILLCKLKRDPCMNSDTYSFKNKMKLNDVEVKETVGGDEKSWELWHEHR GSVRRYTLQGHSTLLKLSWLKDLRELQQCSSLTACSPPEFEVLLADCTTKIGQTIKLTCK VKGTPKPVFSWFKDGLALEDSPHHIITADRAGTWCLILDGVTPKDSGQYVCYASSSVGHA STLAKIVVDAPPRFITRLQSACLLEGEDVQFTCSTHSTPLPRIRWFKDGRELTDQRKYHI ESDARSGILTLTIMNPGETDLGQYECELWNQLGSAKSKAELCAAFTQVIDSQPDQPQVLL TKGRRVPPNQGKCPPQSKEAGFDKKAIYTIRLVNRMTSPEQEVPHRTFIIYEVMILDYKT LSGPKSICQSVSGVIVLPPDSEGWSTAMVKQWLQTDFSPTSIVKMLFQPGYTQPAEGGPE ERDPTTRGHVEVPQFPNDLEERPEVEEELYVPETIQEMTTAPPAIQVPAEDLCVESGQSA TFTIIITGRPTPEIQWYKDGEELLANENVEVVQNGARCSLTVLCPESEDGGIYTCWAYNN SGHTSCQAQLTVEEGPLESQEKEVELGKRRKLLSVYDVHQEIGRGTYGVVKRVTHRRTGE GFAAKFLPLRSSTRTRAFQERDLLSRLAHPRVSCLLDFFSTRRTLVLVTEVCSSHGLLDH LLLKGSVSEREVQLYVQQILEGVGHIHSMNILHLDIKPDNILMVFPPREEIKICDFGFCQ EMDTSRHQYSQFGTPEFVAPEIIHQDPVTIASDIWSIGVVAYLCLMCRCPFVGETDRATL LRVGEGTLNWDAPDLTYRSTGAQDFLRTVLQPDPEKRPTAFECLGHEWFQSEDETDDINT RALKVFISRRKWQRSLTCLGSVLTLRPISELLDAPPRETSVTAPRDTHEPSSTSMSSGSS SEYDEADAWDFFHHCTTTEEDEDEEEEDFDLLMERARIPEPFAKLKWDEEEEEGTMEEEE EEMGGRRSVLSRSISRQSIVSSDASRQPTPQRERRVSRDSSPSLYLSEGDDGSASGSEGG RIARSSLIRSTFYNSSAQLSPMSARHMTLRDKFQAKKQERGRKPLRSSLSSRLNEPLIEY MEDEGDTNHGQRRGSLQSSMLKSCSFDSGVGLSHNAPPQRRSRSLDDYSRRSPGAAKRRE EEGSLSLKEDFTDEEEEKSLVVAPPQIKGRRGSVAVAPAQLTARLQKLGAKLPNAGPEKS PRPEQGRPGEEEGENLAGSQCSLAESLILEHGSETSSRLGSCEDMSHGHPSATHRGRAGE EYDDQEEPLITPSPCSLLQASEVEESEQEPQRRSGQLPIPPRRTTHPNQNPIARNKGQVE RKVLPVKPSPSLSSKAPERPPRASDTEARLQRHSSTPALQAKPPTGKSPRMSPKVGLMNL FRRQSWAGHSYSQLEGTEQGPTLGELEPKTPIMSLRKKMRASASSLTKLFTKSSSKEDLT KGGPIVKGSFPVPPEQEASPGLESAKNKSKFFPFKIPKIPAFKKNKEMPIRPTRPDVHHL EAGGFLLVWRPVQSSDPVVYSVQYSTDGGEWKLLSEEVTDSCYVVKDLPRGAGYVFRVGC ITKTGAGPFSDPSPPVVMATHPEETHIPLIQTESPGSKGSGSGGQPSHKTYSFLSEINRG RFSVVTQCQDSHSQQLFAAKITPCRPEKRQLVLREYQLLKRLNHPHLVQLQTAYITPYYL VLIQELCAGRELLYNLAERDLYSELHVAELLAQILSAVDYLHGRRVVHLDLKSDNMLVTD RNVLKIVDLGSAQSFTPGQTLNIEHIQGQEKVYIVLPKAPEILDGQGVGPETDIWAIGVL AFTMLSADSPFHSDLNWERDRNIRKGKIQFGRCYPGLSEAAINFMKNTLSNKAWGRPSAA ECLQNPWVRGERAPSKHRDSILCFSTDKLQAFLKEREVKRDQVRTKLQGPFFH NT seq 17802 nt NT seq  +upstreamnt  +downstreamnt atgggacacattctatacaagaaccagacccagctactggtggtgaagggtctggaggat gtggaggtgtgtgagagcgagggttgcaccttcgaggtgaccctcaacctgtcctacata gatggcacatggaccaaggacggggtcaggctcaagtcaaagcccacctgtcgcatcgct tcccatcggaataaacacactctcaccttcacccgggtcaccgttggagacactggcctg ttctccttccagactgatggggcccaaagctgtattcaaacctcaggtcaactcattgtc atagccagagacatccagatcatgaaggagttggatgacaaggaagtgactgagaggcag agtgtgaccttcctgtgtgaggtcaactatgagaacgtggacgggcgctggtacagagac aacaccaggatcaaacacggagacaacgtcaagatcagacacgagggtaaaacgcatacc atgtgcttcaagtctgtaaggccagcaaatgctggggagatcaagttcactgcagacagg gtctcctcctatgcaattctcacggtgaaagagctgcctgtgcagatagtgaagcctctg agagtgaagattgctatgtacaaacacaaaggcctgctggagtgccaggtgtcgcgggcc aacgcccaggtcaggtggttcaagaacaggcatgagatccagcccagccggaagcaccag atcgtcagcgatgacgtctacaggcagctccacatcgacgaagtggtctcgtctgatgag gacacctacacctgtgatgctcatgatgacaagacgtcctgtcagctgttagtggaggag caggctatcagcatattgcgggggctgaggtccctggaggtgacggagcccagggaggcc ctgttccaggtggagatcaacctgcgggcggggagaccccccaagtggaccctggatgga gaggtcctgatggaggggcctagagtgagcatagaccgggaggggaccatgcacaccctc tgcttcaacagcacagacagctctatgaccggtaccgtgcagttcaacgccgggaagagc cgctccaccgcacagctcactgtcaaggagcgccctctaaaggtggtccagcccatgcca gacgtggaggctaaagagaacagctcggtcacactgagctgtcagttcgccccctccccc agggtggtgcgctggtacagaggccgcaccgccctgcagacgtccagcaagtacagcatg aggacggagaagagccaggcagagctgaccatccagggcctcaaggagagcgatactggc cagtacagctgcatggctggagggtcaaagagcacggccaaggtcactgtggaggtgcga aggctaaagatcataaggcacctggagcacgtggaggtggaggaggatagcaacgccacg ttcacctgtgagctcaactatgtggtcgccaatgtgcagtggctcctgaacgacaaacat cttaacgccaaccccgtcaccaggatccaaaacatgggcaccatccacagcctcaccatc aaaaagctctgcccccaggagagcagagtcacgttcaaagccggcctgctcaccgagtcc acctccctcaaggtcaaagaaaagccagcggtgttcctgaggtctctagaagacatgtca ggggaggaggaggggaagttgtgtctgcagtgtgagacctctaaggaaacggtcaccccc gtctggaggaaggatggtacagtccttgccagcagtgacaagtatgagctgctcaagttt gggaagtccttagcgctcatcatccatagtctgagtaaggatgatgctgaccactatagc tgtgacctgggcaccagccagaccaaggccaaggtcactgtacatgaccttcacatcacc attgcccagcgtatgaagacggcctctgttctggagggtgagagctgcagtttcgagtgc gtcctctctcatgatgtcatcgacgagccctcctggaccctgaacggtcaacttgtggtc agcaacagccgcttccagagcgtaaacaagggccgcaagtacaagatgaccatcagagat gcaaccttgacggacgccggggacgtagtcttcttcatcaaagacctcagctgcaggacc atgctatttgtcagagagaagccagtgcatgttttcagggacatgatgaatgtcaaagcc accccaggggaggacgctgagctgagctgtgagatcaccaagcctgaggccttcatacgc tggctgaagaatggccatcagatcaggcacagcccccccaagtacgagatcaatgtggag gaccacctggtacggctggtgatcacgaacacctgcatcagagactctggggagtactgc tgtgaagcagacggcattgccacccgggctaagctggaggtcagagagctgcagcacatg tttgcacgtgagctgcgggaggcacaggctgaggaaaagagcaaggtgacgctggagtgt gagacgagattgccggccaagcgggtgacctggctgaagggcatggcggagctccgggcg ggcaagaagtatgtgatgaaacagaagggcgtagtcctctccctcacaatcagctgcctg gagaagggtgacacggacgtgtacacctgcgacgttggcaccatgcagagccgggcgcta ctgaccgtgcatggtcagaaggtgttgatcatggatgagttggaggacgttgagtgtctg gagaatgacacggtgatgttcaggtgccgtatctgtcccagcgactatgttggggtcaag tggtacctggatgagaccttactgtacaccaacaagctgaatgagatccaggtggtcccg gggggataccacagcttaaccttcaaacagctggcccgtaaagactcgggcaccatctcc ttcgaggcaggcgacaagaggtcctacgcctcattgcttgttagagagagacgtccaacc attaccaaaacattggaggattgtgaggccattgagggaggcagtttggtgcttgtgtgt atgacctctaagccatgccacatcctgtggtacaaagatggctgcctaatgtggagctcc tcaaggtactacgtcagtcgctcaggtaacgaggccaggctgaccatcagggaggtcagt aacagcgatgctggggtgtacgagtgcagcgctggatcggtcagcaccaaggctgtcgtc aatgtgaaagccatcccagctgagttcacccagccgctgcagaacatggaggtgaaggag ggggaggatgtgaccctgtggtgtgagttctccctgccgggggttgcgttccactggagg aggggcctggagaacctcagggctggagagaggtacctgatgaagcagaagaagtccctc atctctctgaccatcaccggcccgaagcctgaagactcaggagactacacctgtcagtgc cgagaccacagaacgacagccaccctcacagtccacgctatccccatctccttcaaacaa caattgaagaatattcaggctgaggaaggcaacagtttcacattgcgctgtgagctctcc aaaccgggagtccccgtagagtggaaaaaaggagaggagctgctgaggattggagtgaag ttccagataagaaagagagagaccatatcggagcttcagatagggaaagctgtgccagaa gacagtggagtttacagctgccagtgtgcagaccaaaagaccacggccaccgtcaaaatc agcgccctgcccgttaccttcaaacaaaagctgaggaacgtgcaggttgaggaggggaac aatttggtgttacactgtgagctctctaaaccaggagtccctgtagaatggataatggga ggagaggagctgctgaacaatggagagaagtttcagataaagcagagagagttggtgaat gaactgaagattctggatacaaaacctgaagacagcaatatctacacctgcgtttgtggc aatgtggagaccacagccggtgttactgtcacggcaattcccatcactttcaagcaaaag ctgaggaatctgcagaccgaggaagggaacaccatcagcctgcactgtgagctttctaaa tcaggggtccctgtggagtggaggctgggaggagagatgatactgcaaaatggagacaag tatcagatgaagcagagaggcttggcactggagctcgtcatcagggagcctctgcctgag gacagtggagtctacagctgtgtgtgtcgagaccagaagaccaaggccacagtcaaagtc attgctgtacccgccaccttcagagtgggtctgaagaaccaggaggcccaagagaagggc agtgtgaccctgcgctgtgagttgtctaagtctggcgtcccggtggagtggtggaggggg gagacagaactgtcccaggacctgttagggggaaaataccagatcaaactggaggcgagg atcgctgagatgaccattaccaacgtgcaaccggaggacatgggaaaatacagctgtgtc actggagaccagaagaccaccgctgctgttaaagtgcaagctctccctgtgacgttcaag cgccagctccagaacaccatgatcaaagagggggacagtggggagttctggtgtgagctc tccaagcctggagccccagtggactggaggaaggggagagtcatcctgaagtctggagac aaatatgagatgaagcaggagggatgcatcactaaactgctcatccatgacgtggaggag agtgacgctgggaaatacacctgcaagactaaagacgcccagtcaactgctgagctgacc gtgaagggcctaccccccactttcaaagaacagctgaggaacatggaagttgaggagggt aagactgtgacgctacactgtgagctgtctaagcctgcatcctcagtggagtggaagagg ggagcacagctgttgaagaatgtagacaagtaccagatgaagaagaaagatttactggtg gaattgaagattatcgatgctaatctggaagacagtggggtttacacctgcatttgtggt gaacaaaagaccacagccactgttacaataaatgcacgccccttcacatttatagaagag ctgaggaacgttcaggttgaggagggcaacaatgtgacattgcgctgcgagctctctaaa ccagggatgttggtagaatggatgagaggaacagatctgctgcggaacggagagaagttc cagatgaagcagaaacacgcaacgttggagctgatcatcaggaaaaccatacctgaggac agtggagtctacagctgcgtggtggaggaccagaaaacgtttgccaccatccttatcact gccgtcccagtcactttcaagcagaaactaaagaaccaagaggccctggaggagggcagt gtgacgttgcgctgcgagctgtctaaatcaggagtctctgtggaatggctgaagggagag gagctgctgagggaaggggagaggtaccagatgaaacaggaggggaggactgctgagatg gtcatcaggaacgtggtcctgcaggacgctggggagtatagctgtgtcaccgcctgcaac gtcaagacaacagctgacatcaaagttagggccctccctgtaacattcacacaagaggtc cagaatgtggtgatcaaagagggggacagtggggagttctggtgtgagctctccaagcct ggagccccagtggactggaggaaggggagagtcatcctgaagtctggagacaaatatgag atgaagcaggagggacgcatcactaaactgttcatccataacgtggaggagagtgacgct gggaaatacacctgcaagactaaagacgcccagtcaactgctgagctgaccgtgaaggct cctcccatcacgttcaaggtgaagttgaagaaccaggaagttgaggaggagaacagtgtg acgttattctgcgagctctctaaaccaggactgatggcagagtggaggaagggagaggag ctgctgaagaatggagtgaggtaccagataaagaagagagaggcaacgatggaactgacc atcaggaaagcagtgctcgaggacaccggattctatagctgtgtttacgcagaagccaaa accactgccactgtcaacatcatcgccatacctgtcaccttcaaaatgggtctgaagaac caagaggccccagaggggggcatcgtgaagctgtgctgtgagctgtctaaggctggagtc ccggtggagtggtggaaaggggaggaggaggtgagccctggaggaaggtaccagatgaag ctggagggaaagatagcggagatgcacatcaagaacatccaaccagaggacgtgggggag tacagctgtatattcggagatcagaagaccactgctgaagtcaacgtgagagctgctgca tcagtcttctttgagaaggagctggagagcaaggtggtgatggaggggaagtctgtggtc ctttcctgtgaggtctccagtgttaccgtccccgtcacctggaggaaggactcctgcctg gtcacagatggggagaggttcactttgaagaagaaaggctctgtccacaccctggagatc aggatgttgagtctggaggacgctggggagtacagctgcatcaccagaggaaagaagacc acagccatgctggttgtgaaagagcgtgtgaagatcttgtcaggactgaaggacattaag atcatggccgggcaggacgcagtgtttgtgtgtgagctgtcccacaaggaggtaagcgag ggcgagtggtggctgggctcaagccccctgcagaagaacgaaatgaaccagatgagctgc ctgggccaccagcaccgcctggtcctgaccatgaccacaccagaggagaccgggaccgtg accttcgtggtcggggaagaaaagacctccgcccagttgctggtgctccccaaacccaaa gtactcattgaaaagaagccccgggacatcgtcatcatggaaggggagacggccacatta tcctgtatgacatctgacctctttacccctgtcacatggagaaggaacaatatgcccctc ctgaacggagacaagtatgaaacgcgtaaggagggaaaactcaacctgctgctcatccat gagaccgaaccaggggactctgggatatacttctgtgacactggagacatgcagagcagc gccaatctgactgtcaacgaggtgcctccatactttgaggaggagctgcaggctgtggag gctgaggaggggggaacggccttcctgacctgtgagctgtctaagcctgcagtcccagtc cagtggaggaagggccggctacctctcaggcccaacaggaagtaccagatgaagcaggac ggctgtgtgtttcagctacacatcctggagctgaagaaagaagacggtgggagctacacg ttccaggcaggtggtatagaaaccaccgcctctgtgtctgtgaaagttaaggtactcatt gagaagaagccacgggacaccgtcatcatggaaggggagacggccaccctatcctgttcg acctctgacctcgttaccccggtcacatggaaaaggaacaggatgcccctcctgaacgga gccaagtatgagatgcgtaaggagggcaaactcaacttgctgctcatccatgagaccgaa ccaggggactctgggatatactcctgtgacactggagacatgcagagcagcgccaatctg actgtcaacgaggtgcctccatactttgaggtggagctgcaggctgtggaggctgaggag gggggcacggccttcctggcctgtgagctgtctaagcctgcagtcccagtccagtggagg aagggccggctacctctcaggcccaacaggaagtaccagatgaagcaggacggctgtgtg tttcagctacacatcctggagctgaagaaagaagacagtgggagttacacgtgccaggca ggtggtatagagactaccgcctctgtggctgtaaagcctccctcagataaggcagatcct cccaagacaattcctcccacaaaggctcccacgaaggctccctctcccacttctccacca gaagaggcccaacctggccctctagagcgaaggaaacggggcatgacccggtcatccatt gtggagtcagaggaagacctggagcctgaggaaaaagagacagcggtagaccagcaggag aaacagtcattaaggtctatgggtaaggagactaaggtagaccagcaggagaaacagtca tttgggtctatgggaaaggagacagcggtagacctgcaggagaaacagtcattaaggtct atgggtaaagagacagcggtagaccagcaggagaaacagtcattaaggtctatgggtaaa gagacagcggtagaccagcaggagaaacagtcattaaggtctatgggtaaggagactaag gtagaccagcaggagaaacagaaagtgaaacagccagtaggtatggtgaaggataacata gcagaaaatacacagaaacagctagtaccaccactgaggtctaaagggaaggaggcaact atggtgaaggagacacagatggaccagccggagaaagagccagtgaaacagccagtcaga gctatagtgacggacacagaggagaaaaagtatatggtgaagaagactgaaatagacctg ttggagaaaaagatgaaagaggttggggtacaccaggtggtgaaacaaccagttccacca gtgagacgagcatctatagtgtcggatgctgggatagacgagatgaggaagcagccagtt ccaccatcaagaagagcatctgttgtttcagtttcggatgctggggtagacaaggtgagg aaacagccagttccaccatcaagaagagcatctgttgtttcagtttcggatgctgggata gacgagatgaggaagcagacagttccaccatcaagaagagcatctgttgtttcagtttcg gatgctggggtagacaaggtgaggaaacagccagttccaccagtgagaagagcatctgtt gtttcagtttcggatgctggggtagacgagatgaggaagcagccagttccaccatcaaga agagcatctgttgtttcagtttcggatgctggggtagacgaggtgaggaaacagccagtt ccaccagtgagaagagcatctgttgtttcagtttcggatgctgggatagacgagatgagg aagcagccagttccaccatcaagaagagcatctgttgtttcagtttcggatgctgggata gacgagatgaggaagcagccagttccaccatcaagaagagcatctgttgtttcagtttcg gatgctggggtagacaaggtgaggaaacagccagttccaccagtgagaagagcatctgtt gtttcagtttcggatgctggggtagacgaggtgaggaaacagccagttccaccagtgaga agagcatctgttgtttcagtttcgaatgctggggtagacgaggtgaggaaacagccagtt ccaccagtgagaagagcatctgttgtttcagtttcggatgctggggtagacgaggtgagg aaacagccagttccaccagtgagacgagcatctatagtgtcggatgctggggtagacaag gtgaggaatcagccagttccaccagtgagacgagcatctatagtgtcggatgctggggaa gacaaggtgaggaatcaggcagttccaccagcgagacgagcacctatagtgtcggatgct gggatagagcagatagttagatctaaaaaggagatagatatagaagtagaccatcagaac aaacagtcagtgaagtctatggtgaaggagacagatgaagaccatcaggagaaacagcca gtgaagtatatggtgaaggagacagaggtagaccagagggacaaacagccagtaaggttt acagtacaggagacggaaaaacccaagattgcggaggatggtaaccaactccatatctca gtgggtgagtccttcactgaggctcccacccaggtaagcgtcaaccagaagaccagcaag cctgtagttgctgttgctggagttcccaaggggctccagatgactaagcaatttgacgag actgaacctgacatggaaatcagtgttgaggacgaacctgaaatgctggaagccgccatc aagatccaggcagctttcaaaggatacaagactcgcaaagatatgcggccagtcttcaag caggtgttcaagaaccagaacgttgagaccaacggtaccatccagctagcatgcatggtg gaagggaagcccaacgcagtacgctggctgaagaatggccagcagatcataggagaccaa cgccaccgcatgaacacctcagaggatggtgtctgcacactggtgatcatcaacatgtca gccatagacactggggtctatacgtgtgaggtggtcaacaagtttggtgtgacctcatat aatggcaacattaccgtgggtcaacctcaaaagcctccatcctccacccagaggcctgca gccccagcacagccctccaccccttctgtgcacccagtcctggcctctgttggccctctc cagccagcccagacctccacctctggaaaggagactatgggttctgtggagagcgagggg atctccctgtggcaggcctacaacctgaccgaggaggattcccgcatgaccctgcaggag aggaggagggcctccctcatcgccgccagctctatgtctagtccatctgactacgacaca gctccagatttcatagagcctgttgacatcatccccaaagatcaccccagggaaaaggaa gccattaagtcagaagaccagttacaacataaggttaaagaacagaaagtcacccctcaa ccaccaaagaggcatttgaaggtcaaagctactgatgccaagctgaggactctgtccccg aaacaccaccgtgcccacatgtctgctgctcttacaggctctggctcagagtcagatggt gacgaggacagaaaagagacatttgctatctatgtggccagagctaagtgcagctctcaa cacagtggcaataaggcgagctttgtgttgaaggagggccagtacgtggaggtcttggac tctgtccaccctgagacgtggctggtccgcaccaaaccctccaagaacaccccctcacgc caaggatgggtctctcctgcatacctggagaagaagagaacgacattcccacaagtgagg acaccacaacaggagatggatggatcaggttctacaggggaggagtacaggagaacagta agccaattgatccaggggctgattgatggggaggaagagtttgtgaaggtgatgaaggac tttacgtcccactacctgcaccacttagacaccagccctgatgtccccatcaacatcatc aaccagaaagaaaccatcttccgcaatatcaaggacatcatggctttacatgagaggtct attctgcctaggctgagcgagtgttctactgatgatgatgtggccatgcacctggtcaaa catgcagaggactttgagaagtatctgcagtacatgatgggccaaacacaggcagagacc tgtgtgactgacaagaccatccagcagtacttcaagcataacacggagacagagcctgag caccccaaaactgcagtgctggatgtcatcaccttcttacagagaccagtggagaggatt cagacctaccaggccttactcaaggagctgatcaagaacaaggctaagtgtgggaaaagc tgccgtctgctggaggatgcattctccatggtgtcctgtctgccctggcgttctgacaac ctgcaccaggtgtctctgattgagaactaccctgccccactcactgcactgggggaaccc gtccgccagggttccctcactgtgtgggaggagtctcctgagatcaagacatcctccagg tggcaccagaggcaggtgtttctctttaaggactgtatcctcctctgtaagctcaagaga gacccctgcatgaactctgacacctattccttcaagaacaagatgaagctgaatgatgtg gaggtgaaggagacagtggggggagatgagaagtcctgggagctgtggcacgagcaccgg ggctcagtgaggaggtacacactgcagggtcactccaccctgctcaagctgtcctggctc aaagacctgagagagctgcagcaatgctccagcctgactgcctgcagtccaccagagttc gaagttctcctggcagactgcacaacaaagatcgggcagacaatcaaactgacctgcaaa gtcaaaggaacacccaaaccagtgttcagctggttcaaagacggcctggccctagaggac agcccccaccacatcatcactgcagaccgggcaggcacctggtgtctcatcctggacggg gtcactcccaaggactctggacagtacgtgtgctacgcctccagctccgtgggtcatgct agcacactggccaagatagtggtggacgcaccccccaggttcattactaggctgcagagt gcatgtctgctggagggagaggacgtccagtttacctgctccacacacagcacaccgcta ccccgaatcaggtggtttaaggatggcagagagctgacagaccagaggaagtaccacata gagagtgatgcccgcagtgggattctcactctcaccatcatgaaccctggagagacagac ctgggacagtatgagtgtgagctgtggaaccagttgggcagtgccaagagtaaagcagag ctgtgcgccgccttcacacaagtgattgacagtcagcctgaccaaccacaggtcctcttg accaaaggtaggagagttccacccaatcaaggtaaatgtccacctcagagtaaggaagca ggttttgataagaaggctatctacactataagactggttaataggatgacatcccccgag caggaagtacctcacagaaccttcatcatatatgaagtaatgattttggattataaaact ctaagtggacctaagagcatctgtcagtctgtgagtggtgtcattgtgcttcctccagac tcagagggctggtccactgccatggtgaagcaatggctgcagacagacttcagccccaca tctatcgtcaaaatgctcttccagcctggatacactcagccagctgagggtggcccagag gaaagggaccccaccaccagaggccacgtggaggtgccacagttccccaatgatcttgag gagagacctgaggttgaggaggaactttatgtccctgagaccatacaggaaatgacaaca gctcctcccgccattcaggtgccggcagaggacctgtgtgtggagtctggccaatcagct accttcaccatcatcatcacaggaaggcccacccccgagattcagtggtacaaggatgga gaggagctgttggccaatgagaatgtggaggtggtccagaatggtgcccgctgctctctg actgtgctgtgcccggagagcgaggacggtggcatctacacctgctgggcctataacaac tcaggacacacctcctgtcaggctcagctcacagtggaggagggtccactggagtcgcag gagaaggaggtggagcttgggaagaggaggaagctgctctctgtgtatgacgtccatcag gagatagggagaggcacatatggggtggtgaaacgggttacccacaggaggactggcgag ggctttgccgccaagttcctgcccctgaggagcagcacaaggaccagggcgttccaggag agggacctgctctcccggttggcccaccccagggtgtcctgtctgctggacttcttctcc acgcgcaggaccctggtcctggtcactgaagtctgctcttctcatggtcttcttgatcat ttgctgttgaagggatcggtcagtgagagagaggtgcagttgtacgttcagcaaatcctg gagggagttggtcacattcacagcatgaacatccttcatctggacatcaaaccggacaat atcctgatggtgtttccacccagagaggagatcaagatctgtgactttggcttctgtcaa gagatggacacttccagacaccagtacagtcagtttggaactccagagtttgtagcccct gagatcatacatcaagaccctgtcactatagcaagtgatatctggtccattggtgttgtg gcgtatttatgtctgatgtgccgctgtccgttcgtgggggagacggaccgggccactctg ctgagggtgggggaggggacactgaactgggacgcacccgacctcacctacaggagcacc ggggcccaggacttcctccgcacggtcctgcagccagacccagaaaagcgaccaactgca tttgagtgtctggggcatgaatggttccagagcgaggatgaaactgatgatatcaacaca agggctctgaaagtctttatttcaaggaggaaatggcagcgttctctgacctgcctgggc tcggtcctcaccctgaggcccatctcagagctgctcgatgcccctcctcgggagacctct gtcacggccccgagggacacccatgagcccagcagcacctcaatgagcagcggctcctcc tcggagtacgacgaggctgacgcctgggacttcttccatcactgcaccaccacagaggag gatgaagatgaggaggaggaagacttcgacctcctcatggagagagccaggatcccagag cccttcgccaagctgaaatgggacgaagaggaggaggaagggaccatggaagaagaggaa gaggagatgggaggacggaggagcgtgctgagtaggagcataagcaggcagtccatagtg tcttcagacgcctccaggcagccgacgccccagagggagaggagggtcagccgagacagc agcccgtccctgtacctctccgagggggatgacggctccgcgtccgggagtgaaggaggg cgcatcgccaggagcagcctgatccgcagcaccttctacaatagctctgcgcagctctct cccatgtccgcccgccacatgaccctcagagacaagttccaggccaagaagcaggagagg ggccgcaaaccgctccgcagcagcctctctagccgcctcaatgagccgctcattgagtac atggaggacgagggagacaccaatcacgggcaacggcgggggtctttgcagtcgtccatg ctcaagtcctgctccttcgacagcggggtcggcctctcgcacaatgcacccccgcagagg aggagcaggtcgttggacgattactcccgacgctcaccaggagccgccaaacgcagagaa gaggagggttctttgagtcttaaggaggatttcactgatgaggaggaggagaagagcttg gtcgttgcccctccccaaatcaaaggtagaagaggttcagtggcagtggctcccgctcag cttacggccaggcttcagaaactgggtgcaaaattgcccaatgctggtccagagaagagc cctaggccagagcaggggagaccaggggaggaggagggggagaacctggctggctcgcag tgctccctggctgagtccctcatcctcgagcatggctctgagacctccagcaggctgggc tcctgtgaggatatgtcccacggccacccttcagccacacatagagggagagcaggagaa gagtatgatgaccaggaggagcccctaatcaccccgtccccctgctccctactccaggca tctgaggttgaggaatctgagcaggagccccagcgccggagcggccaacttccaatccca ccgagaaggacaacacaccccaaccagaacccaatagccagaaataagggtcaggtagag aggaaggtcctgccggtgaaacccagccccagcctgtccagcaaggccccagagaggccc ccaagggccagcgacacagaggcacgactccagaggcattcgtccaccccggccctccag gccaaaccgcccacggggaagtctcccaggatgtcacccaaagttgggttgatgaatctg ttccgtagacagtcctgggcagggcattcctactcccaactggagggcacggagcaggga cccacgctaggggaattggagcccaaaacccccatcatgtcactcaggaagaagatgaga gcatcagcctctagcctcaccaagctgttcactaaatcgtccagcaaggaagacttaacg aagggagggccgatcgtaaagggttcatttcctgttccgcctgagcaagaggcaagccct ggcttggagagcgccaaaaataaatccaagttcttcccattcaaaatacctaaaatacct gcattcaaaaagaacaaagaaatgcctatccgccccaccaggcctgatgtgcaccatttg gaggcaggtggatttctgctggtatggagaccagtgcagtccagcgacccagtggtttac agtgttcagtacagcacagacggtggggagtggaagctcctgtcggaggaggtgacagac agttgctacgtggtgaaggacttacccagaggagcaggatacgtgttcagggtgggctgc atcacaaagacaggggcaggacctttcagtgacccttcaccacctgttgttatggcaacc catcctgaagagacccacattcccctcatccagaccgagtccccaggttcaaagggcagt gggtcaggaggtcaacctagccacaagacctacagcttcctatcagagatcaacaggggt cgtttcagcgtggtgacccagtgtcaggacagccatagccagcagctatttgctgccaag atcaccccctgcaggccagagaagagacagctggtgctcagggagtaccagctgctgaag aggctcaaccacccccacctggtgcagctgcagacggcctacataaccccttactacctg gtgctcatccaggagctgtgtgccggcagagagctgctctacaacctggctgagcgagac ctgtattctgagctccatgtagcagagctgctggctcagatcctgagtgctgtggactac ctgcacggtcgccgcgttgtccacctggacctcaagtcagacaacatgctggtgacggac cgcaacgtgctgaaaatcgtagacctgggctctgctcagtccttcacgcccggacagaca ctcaacatagagcacattcagggacaagagaaagtttacattgtccttcctaaagctccg gaaatcctcgacggacaaggagtcggacctgagaccgatatctgggctattggggtgtta gcttttacaatgttgagtgcagatagcccgttccattcagacctaaactgggagagggac aggaacatccgaaaggggaagatccagtttggccgctgctaccctggcctgtcagaggca gcaatcaacttcatgaagaacacactgagcaacaaggcctgggggagaccctcagcagct gagtgcctccagaacccttgggtacggggtgagcgggccccctccaaacacagagactcc atcttgtgtttctctaccgacaagctgcaggccttcctcaaggagagagaggtgaaacga gaccaggtccgcaccaagctgcaaggcccgttcttccattga

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