Conger conger (European conger): 133121743 Help Entry 133121743         CDS       T10633                                  Name (RefSeq) ryanodine receptor 2-like   KO K04962   ryanodine receptor 2 Organism ccog  Conger conger (European conger) Pathway ccog04020   Calcium signaling pathway ccog04260   Cardiac muscle contraction ccog04261   Adrenergic signaling in cardiomyocytes ccog04371   Apelin signaling pathway Brite KEGG Orthology (KO) [BR:ccog00001]  09130 Environmental Information Processing   09132 Signal transduction    04371 Apelin signaling pathway     133121743    04020 Calcium signaling pathway     133121743  09150 Organismal Systems   09153 Circulatory system    04260 Cardiac muscle contraction     133121743    04261 Adrenergic signaling in cardiomyocytes     133121743  09180 Brite Hierarchies   09183 Protein families: signaling and cellular processes    04040 Ion channels [BR:ccog04040]     133121743    04990 Domain-containing proteins not elsewhere classified [BR:ccog04990]     133121743 Ion channels [BR:ccog04040]  Voltage-gated cation channels   Ryanodine receptor    133121743 Domain-containing proteins not elsewhere classified [BR:ccog04990]  EF-hand domain-containing proteins   Other EF-hand domain-containing proteins    133121743 BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  RYDR_Jsol RYDR_ITPR RyR RR_TM4-6 SPRY Ins145_P3_rec MIR RIH_assoc Ion_trans EF-hand_7 EF-hand_1 EF-hand_8 EF-hand_6 Hydantoinase_B Motif Other DBs NCBI-GeneID:  133121743 NCBI-ProteinID:  XP_061087166 LinkDB All DBs Position 2:complement(15701259..15875268) Genome browser AA seq 4959 aa AA seqDB search MAEGGEGEDEIQFLRTDDEVVLQCSATIHKEQQKLCLAAEGFGNRLCFLESTSNSKNVPP DLSICTFVLEQSLSVRALQEMLANTEEKAEGQVDVEKWKFMMKTAQGGGHRTLLYGHAVL LRHSYSGMYLCCLSTSRSSTDKLAFDVGLQEDTTGEACWWTIHPASKQRSEGEKVRVGDD LILVSVSSERYLHLSYGNGSLHVDAAFQQTLWSVAPICSGSEVAQGYLIGGDVLRLLHGH MDECLTVPSGEHGEEQRRAVHYEGGAVSIHARSLWRLETLRVAWSGSHTRWGQPFRLRHV TTGKYLSLLDDKGLLLTDKEKADVKSTAFCFRSSKEKLDFGVRKEVDGMGVPDIKYGDSV CYIQHVDTCLWLTYQAVDAKCARMGGVQRKAIMHHEGHMDDGLTLSRSQHEESRTARVIR STVFLFNRFIRGLDALSKKGKTSTLDLPIESVSLSLQDLIGYFQPPDEHLEHEDKQNRLR ALKNRQNLFQEEGMINLVLECIDRLHVYSSAAHFSDVAGKEAGEAWKSILNSLYELLAAL IRGNRKNCAQFSGSLDWLISRLERLEASSGILEVLHCVLVESPEALNIIKEGHIKSIISL LDKHGRNHKVLDVLCSLCVCHGVAVRSNQHLICDNLLPGRDLLLQTRLVNHVSSMRPNIF LGISEGSAQYRKWYYELIVDQVETFVTAEPTHLRVGWATTDGYSPYPGGGEGWGGNGVGD DLYSYSFDGLHLWSGCIARTVSSPNQHLLRADDVVSCCLDLSAPSISFRINGQPVQGMFE NFNSDGLFFPVTSFSAGVKVRFLLGGRHGEFKFLPPPGYAPCFEAVLPREKLRVEHSQEY KQDHGGMRDLLGPTVSLTQAAFTPTPVDTSQIVLPPHLERIREKLAENIHELWVMNKIEL GWTYGTVRDDNKRQHPCLVEFSKLPEQERSYNLQMSLETLKTLLALGCHVGVSDEHAEEK VKNLKLSPMYELSSGYKPAPMDLGHIKLASTQEAMVDKLAENAHNVWARDRIRQGWTYGI QQDVKNRRNPRLVPYALLDERTKKSNKDSLREAVRTLLGYGYNLEAPDQDHAARSDISNL LAERFRIFRAEKTYSVNAGKWYFEFEVVTAGEMRVGWARPGCLPDQELGSDEQAFVFDGF KAQRWHQGNEHFGRSWQQGDVVGCMVDMNEHTIMFTLNGEVLLDDSGSELAFKDFEVWEG FIPVCSVGVSQVGRMNFGKDVSTLKYFTICGLQEGYEPFAVNMNRDLTMWLSKRLPQFIP VPPNYEHIEVMRIDGTVESSPCLKVMQRSFGSQNSNTDIAFYRLSMPIECVESFSKSPGG TLPSNGSFFSPKKELEDFETVSDFEVLMKTAHGHLGSNGPEKDKDEFNNHKDYNQEKPFK LKQRFMMKRTKTDFSTSHSSARLSEEVLADERDDYEYLMQTSTYYYSVRIFPGQEPSSVW VGWVTSDFHQYDTAFELEKVRTVTVTLGDEKGKVHESIKRSNCYMVWAGESTSPGQGRNN NGLEIGCLVDTANGLLTFTANGKELSTYYQVEPSTKLFPAVFAQATSPNVFQFELGRIKN VMPLSAGLFKSERKNPMPQCPPRLHVQFLTPVLWSRVPNHFPKVETSRINDRHGWLVHCS EPLQFMSLHIPEENRSVDILELTEQTDLLKFHYHTLRLYSAVCALGNNRVAHALCSHVDE AQLLYAIENKYMPGLLRTGYYDLLIDIHLSTYATARLMMNNEYIVPMTDETKSITLFPDE KKKHGLPGIGLSTSLRPRMHFSSPSFVSVGGDFFQYSPEFPLDILKTKTIEMLTEAVREG SLHVRDPIGGSTEFLFVPLIKLFYTLLIMGVFHNGDLKNILQLIEPSVFSEDSGHERADA PDGNGFKGELRIEGAGGEDVGRAGNVPKEGLLQMKLPEPVKLQMCHLLQYLCDCQVRHRI EAVVAFSDDFVANLQDNQRFRYNEVMQALNMSAALTARKTKEFRSPPQEQINMLLSFKDE KQDCPCPEDIREQLLDFHEDLMTHCGIEIDDDKANEADGDFTIRGRLLSLVEKVAYLKKK MADLPKKKKSKKPTTLQHLISETMVRWAQESVIEDPELVRAMFVLLHRQYDGIGGQVRAL PKTYTINSVSVEDTINLLASLGQIRSLLSVRMGREEEKLMIRGLGDIMNNKVFYQHPNLM RALGMHETVMEVMVNVLGGGESKEITFPKMVANCCRFLCYFCRISRQNQKAMFDHLSYLL ENSSVGLASPSMRGSTPLDVAAASVMDNNELALALREPDLEKVVQYLAGCGLQSCLMLVS KGYPDIGWNPVEGERYLDFLRFAVFCNGESVEENANVVVRLLIRRPECFGPALRGEGGNG LLAAMEEAIKISEDPSRDGPSPTSESSRTLDIVDDEEDDTIHMGNAIMTFYAALIDLLGR CAPEMHLIHAGKGEAIRIRAILRSLIPIEDLEGVISIPFPMPTLAKDGTVVEPDMSAGFC PDHKAAMVLFLDRVYGIEDQNFLLHLLEVGFLPDLRAAASLDTAALSATDMALALNRYLC TAVLPLLTKCAPLFAGTEPYASLIDSLLHTVYRLSKGCCLTKAQRDAIEECLLAVCGKLR PSMMQHLLRRLVFDVPLLNEHTKMPLKLLTNHYERCWKYYCLSGGWGSFGAASDEELHLS RKLFWGIFDALSQKRYDQELFKLALPCLSAVAGALPPDYMESNYVAMMEKQSSMDAEGNF NPQPVDTSNVTVPEKLDYFINKYAEHSHEKWSTDKFANGWVHGDQLCEASKVHPLLKPYK GLSEKDKEVYRWPIKESLKTMLAWGWSIERTREGDPAGLHNRARRISQSSQLSIEGTHGF SPRPIDMSNVTLSRDLHSMAELLAENYHNIWAKKKKIELEAKGGGSHPLLVPYDTLTAKE KSRDREKAQDILKFFQINGYAVSRAMKEQELDTPSIEKRFAYTFLQQLIAYVDEAHKHMM EFDVGTWGKGEKIPHEQQMKFFGKVVLPLVDQYFKNHRLYFLSTAIRPLSSGGHASNKEK EMITSLFCKLGVLVRHRISLFGNDSTSIVNCLHILGQTLDARTVMKTGLDTVKAALRAFF DNAAEDLEKTLENLKQGQFTHTKTQPKGVTQIINYTTVALLPVLSSLFEHIGQNLFGEDL ILDDVQVSCYRILNSLYSLGTSKSIYVERQRPALGECLAAFSGAFPVSFLEPHLNKYNTY SIYNTKGSRDRAALGLPAQVEDMSPLIPSLEKSLEEIMELAESGMRYTQMPHVMEVVLPM LCSYMSHWWEHGPENNPERADKCCTSLTSEHMNTLLGNILKIIYNNLGIDEGAWMKRLAV FSQPIISKAKPQLLKTHFLPLMEKLKKKAATVLLDEEHMKAEGRGEMSEAELLILDEFTI LVRDLYAFYPLLIRFVDYNRAKWLKEPNPEAEELFRMVAEVFIFWAKSHNFKREEQNFVV QNEINNMSFLITDTKSKMSKGAMSDQERKKMKRKGDRYSMQTSLIVAALKRLLPVGLNIC APGDQELIALAKNRFTQKDTEDEVREIIRNNLHLQGKLEDPAIRWQMALYKDLPNRSEDT SDPEKTVERVLDIAHVLFHLDQVEHPQRSKKAVWHKLLSKQRKRAVVACFRMAPLYNLPR HRAVNLFLQGYEKSWIETEEHYFEDKLIEDLAKPGGEEPSEEDEGAKRIDPLHQLIQLFS RTALTEKCNLEEDNLYMAYADIMAKSCHDEEDEDGEEVKSFEEKEMEKQKLLYQQARLHD RGAAEMVLQTISASKGEMGPMVASTLKLGIAVLNGGNSTVQQKMLDYLKDKKDVGFFQSL AGLMLSCSVLDLNAFERQNKAEGLGMVTEEGSGEKVMQDDEFTCDLFRFLQLLCEGHNSD FQNYLRTQTGNNTTVNIIISTVDYLLRVQESISDFYWYYSGKDVIDEQGQRNFSKAINVA KQVFNTLTEYIQGPCTGNQQSLAHSRLWDAVVGFLHVFAHMQMKLSQDSSQIDLLKELMD LQKDMVVMLLSMLEGNVVNGTIGKQMVDMLVESSNNVEMILKFFDMFLKLKDLTSSDAFK EYDPDGKGVISKRDFHKAMESHKHYTQSETEFLLSCAETDENELLDYEEFVERFHEPAKD IGFNVAVLLTNLSEHMPHDTRLQTFLELAESVLNYFQPYLGRIEIMGSAKRIERVYFEIS ESSRTQWEKPQVKESKRQFIFDVVNEGGEKEKMELFVNFCEDTIFEMQLAAQMSDIGERS ASKEESEKEKPEEENPEMGFFSVTTVRTALLALRYNVMMLMKVLSMKSLKKQMKKMKKMT VKDMVTTLIAFYWSLLMGLLHFAFSVSRGFFRIVYSTFLGGSLVEGAKTMKVADLLANMP DPTQDEVRGEGEEAEKRHSDKASAEEDLADLAVNIEDTDLLSDIFGLDLRREGGQYKLMP HNPNASLADLLNSPVPPPPTPSPELRRRHQGQGSTEEDREGKEESQSEPEKAEGENGEKD VKPKDEKPKQKVRQHHTSKSEEPELQESAFWKKIIAYQRKLLNYFARNFYNMRMLALFVA FAINFILLFYKVSTSSAVVEEKEVVYAGPSDTSVRWSPVEGVPHRTVTVHFVLEESSGYM EPTLRILAILHTVISFFCIIGYYCLKVPLVIFKREKEVARKLEFDGLYITEQPSEDDIKG QWDRLVINTQSFPNNYWDKFVKRKVMDKYGEFYGHDRISELLGMDKAALDFSDAHEKKKP KKDSSLVAVLNSVDVKYQIWKLGVVFTDNSFLYLAWYMTMSILGHYNNFFFAAHLLDIAM GFKTLRTILSSVTHNGKQLVLTVGLLAVVVYLYTVVAFNFFRKFYNKSEDGESPDMKCDD MLTCYMFHMYVGVRAGGGIGDQIEDPAGDEYEIYRIIFDITFFFFVIVILLAIIQGLIID AFGELRDQQEQVKEDMETKCFICGIGNDYFDTVPHGFETHTLQEHNLANYLFFVMYLINK DETEHTGQESYVWKMYQERCWEFFPAGDCFRKQYEDQLN NT seq 14880 nt NT seq  +upstreamnt  +downstreamnt atggctgaagggggggaaggcgaggatgaaatccagttcttacgaactgatgatgaggtg gtgctccagtgttccgccactattcacaaggagcagcagaagctatgtctggcagccgag ggcttcggaaacagactctgcttcctggagtctacctcaaactctaagaatgttccgccg gacctgtccatctgcaccttcgtgctggaacagtcgctgtcagtccgggccctgcaggag atgctggccaacaccgaggagaaagccgaagggcaagttgatgtggaaaaatggaaattc atgatgaagacggcccaaggagggggccaccgtaccctgctctacggacacgcagtgctg ctacgacactcctacagtgggatgtacctttgctgtttgtccacgtcacgatcttcaacg gataaactggcgtttgatgttggactgcaagaagacacaacaggtgaagcctgctggtgg accattcatcccgcctccaagcagaggtcagagggcgagaaggtgcgtgtcggagacgac ctcatcctggtcagcgtctcctcagaacgctacctgcatttgtcctacgggaacgggagc ctgcacgtggacgccgccttccagcagaccctctggagcgtggcgccaatctgctccggg agcgaagtcgcgcaagggtacctgataggcggggatgtcctgaggctgctgcacggtcac atggacgagtgtctgaccgtcccgtctggagagcacggggaggagcaacgcagggcggtg cactacgaggggggagccgtgtccatccacgcccgctccctctggaggctggagaccctg cgagttgcgtggagcgggagccacacccgctgggggcagcccttccgcctgagacacgtc accaccggcaagtacctcagtctcctggacgacaagggcctgctgctgacggacaaggag aaggccgacgtcaagtccacagccttctgcttccgctcctccaaggaaaagctggacttc ggggtgaggaaagaggtggacggcatgggagttccggacataaagtacggggactcggtg tgctacatccagcacgtggacacctgtctgtggctgacgtaccaggcggtggacgccaaa tgcgcacggatgggcggtgtgcagcgtaaggccatcatgcaccacgagggccacatggac gacgggctgacactgtcccgctcacagcacgaggagtcccgcacggccagggtcatccgc agcacagtcttcctcttcaaccgcttcatcagaggcctggatgccctgagcaaaaaaggg aagacctcaacgctagatctgccaatcgagtctgtcagcctgagcctgcaggatctgatt ggctacttccagccgcccgatgagcatctagaacatgaggacaagcaaaacaggctgcgg gcattgaagaacagacagaatctcttccaggaagaggggatgattaacttggtcctggag tgtatcgaccgtctacacgtgtacagcagcgctgctcatttctccgatgtcgccgggaag gaagccggggaggcctggaagtctatcctaaactcattatacgagctactggcggctttg ataagggggaacaggaagaattgcgctcagttttccggctccttggattggctgatcagc aggctggagaggctggaggcctcatctgggattctggaggttttgcactgcgttcttgtg gaaagtccagaggccctcaacatcatcaaagagggccacattaagtctatcatctccctc ctggacaagcacgggcggaatcacaaggtcctggacgttctctgctccttgtgtgtgtgt cacggcgtggcggtgcggtccaaccagcatcttatctgtgacaacctgctgccaggacgg gacctgctcctccagacacggctggtgaaccacgtcagcagcatgcggccaaacatcttc ctgggcatcagcgaaggctccgcccagtacaggaagtggtactacgagctcattgtggac caggtggagaccttcgtcacggcagagcccacccacctgcgcgtcggctgggcgaccacc gacgggtactccccctaccccgggggcggagagggctgggggggcaacggcgtgggcgac gacctctactcctacagcttcgacgggcttcacctctggtcaggctgcatcgcgcgcacg gtgagctcgcccaaccagcacctcctccgggccgacgacgtggtcagctgctgcctggac ctcagcgcccccagcatctccttccgcatcaacgggcagcccgtccagggcatgttcgag aacttcaactccgacgggctcttcttccccgtcaccagcttctcggcgggggtgaaagtg cgcttcctgttgggcgggcggcacggagagttcaagtttctcccgcccccggggtacgcc ccttgcttcgaggcggtgctgcctcgggagaagctgagggtggaacacagccaggagtac aagcaggaccacggtgggatgcgcgacctgctaggcccgaccgtgtccctcacgcaagcg gccttcacccccacgcccgtggacaccagccagatcgttctgccccctcacttggagcgg atccgggagaagttggccgagaacatccacgagctctgggtcatgaataagattgaactt ggctggacgtacgggactgtgcgagatgacaacaagagacagcacccctgcctggtggag ttctccaagcttccagaacaagagcgcagttacaacctgcagatgtcactggaaaccctg aagactctcctggccctgggttgccatgtcggtgtgtctgacgagcatgcagaagagaag gtgaaaaatctgaagctgtcccccatgtatgagctgtcgagtggctacaagcccgccccc atggacctgggccacatcaagctggcctccacgcaggaggccatggtggacaagctggcg gagaatgcccacaacgtgtgggccagggaccgcatccggcagggctggacctacggcatc cagcaggacgtgaagaaccggagaaaccctcgcctggttccgtacgccctgctggatgag aggaccaaaaagtccaacaaggacagcctgagagaggcggtacgcaccctcctggggtac gggtacaatctggaggccccggaccaggatcacgccgcgaggtctgacatcagcaacctg ctggccgagcggttccggatcttccgtgcggagaagacgtacagtgtgaacgccgggaag tggtactttgagtttgaggtggtgacggcgggggagatgagggtcgggtgggccaggcct ggctgcctgcctgaccaggagctgggatccgacgagcaggcttttgtttttgatggcttc aaggcgcagcgttggcaccaggggaacgagcacttcggccggtcctggcagcagggcgac gtggtgggctgcatggtggacatgaacgagcacaccatcatgttcaccctcaacggcgag gttctcctcgacgactcgggctctgagctggccttcaaggactttgaggtttgggaagga ttcattccggtgtgcagcgtgggtgtgagtcaggtgggcaggatgaacttcgggaaggac gtcagcacactcaagtatttcacgatctgcggcctgcaggagggctacgagccgttcgcg gtcaatatgaaccgcgacttgaccatgtggctgagtaagaggctgccacagttcatccct gtcccacccaactacgagcacatcgaggttatgaggatcgatgggacagttgagagctcg ccgtgtttgaaggtcatgcagaggtcattcgggtctcagaacagcaacaccgacatcgcg ttctaccgcctgagcatgcccatcgagtgcgtggagagtttctccaaatccccggggggc actctgccatccaacggcagcttcttctcgccaaagaaagagctggaggactttgagacg gtctccgactttgaggtcctcatgaaaactgctcatggacacttgggttccaacggccca gagaaagacaaggacgagtttaacaaccacaaggactacaaccaagagaagccttttaaa ctcaaacaaaggttcatgatgaagcggaccaagactgacttcagcaccagtcactcatct gcccgcctgtcagaggaagtgctggctgacgagagggacgactatgagtacctgatgcag acctccacgtactattattcggtgaggatcttccctggccaggagccctccagcgtgtgg gtgggctgggtaacatctgatttccaccaatacgacacagccttcgagctggagaaggtc cgcactgtgaccgtcactctgggggacgagaagggaaaggtgcacgagagcatcaagcga agtaactgctatatggtgtgggcgggagagagcaccagcccaggacagggccgaaacaac aacgggctggagatcggctgcctggtggacaccgccaacgggctgctgaccttcaccgcc aatggcaaggaactcagcacctactaccaggttgagcccagcaccaagctgttccctgca gttttcgcacaggccaccagccccaacgtgtttcagttcgaactgggacggataaagaac gtgatgcccctatcggcgggcctgttcaagagcgagcggaagaaccccatgccccagtgc ccgccccggctgcacgtccagttcctcacgcccgtcctgtggagccgggtgcccaaccac ttccccaaggtggagacgtcccgcattaacgatcggcacggctggctggtgcactgctct gagccgctgcagttcatgtccctgcacatccccgaggagaacaggtcagtggatatcctg gagctaacagagcagacagacctgctgaagttccactaccacaccctgaggctgtactca gccgtctgcgccctgggcaacaaccgcgtggcgcacgccctctgcagccacgtggacgag gcgcagctgctctacgccattgagaacaagtacatgccgggcctgctgcggacaggctac tacgacctgctcatcgacatccacctcagcacctacgccacggcccgcctcatgatgaac aacgagtacatcgtgcccatgacggacgagaccaagagcatcacgctcttccccgacgag aagaagaagcacggcctgccgggaatcggcctcagcacctccctccgtcccaggatgcac ttctcctcgcccagcttcgtcagcgtgggcggcgacttcttccagtacagccccgagttc ccgctggacatcctgaagaccaagaccatcgagatgctgacggaggccgtgcgggagggc agcctgcacgtgcgcgaccccatagggggcagcaccgagttcctgttcgtgcctctcatt aagctgttctacaccttgctcatcatgggcgtcttccacaacggcgacctcaagaacatc ctgcagctcatcgagcccagcgtcttctcggaggactcggggcacgaacgagccgacgcg cccgacggaaacggcttcaagggcgagctccggatagagggagcggggggagaggatgtg gggagggcgggcaacgtccccaaagagggactgctccagatgaagctccccgagccggtc aagctgcaaatgtgccatctgcttcagtacctgtgtgactgccaggtgaggcataggatc gaggcggtggtggccttctccgacgactttgtggccaacctccaggacaaccagcgcttc cgctacaacgaggtgatgcaggcgctcaacatgtccgccgcgctgaccgctaggaagacc aaagagttccgatcgccaccacaggaacagatcaacatgctgctgagctttaaggatgag aagcaggactgcccgtgtccggaggacatcagagaacagcttctggacttccatgaggac ttaatgacccactgtggaattgagattgatgatgacaaggcaaatgaagcagatggggat ttcaccatcagaggtcgtctcctgtccctcgtcgaaaaagtggcctacttgaagaagaaa atggcggacttgccaaagaaaaaaaagtcgaagaagcccaccactttacagcatctgatc tctgagaccatggtgcgctgggcccaggagtccgtgatcgaggacccggagctggtccgg gccatgttcgtcctgctccaccggcagtacgacggcatcggggggcaagtccgcgccctg cccaagacctacaccatcaactccgtgtccgtggaggacaccatcaacctgctggcgtcc cttggccagatccgctccctgctgagcgtacgcatgggccgggaggaggagaagctgatg atccgaggcctgggagacattatgaacaataaagttttctaccagcacccaaacttgatg agggcactgggcatgcacgaaaccgtcatggaggtgatggtgaatgttctgggaggagga gaatcaaaggaaatcacatttcctaagatggtggccaactgctgtcgttttctttgctac ttctgtcgcatcagtagacaaaaccaaaaagccatgttcgatcacctcagttacctgctg gaaaacagcagcgtcggccttgcgtctccctccatgaggggttccactcccctggacgtg gccgctgcctctgtgatggataacaatgagctggccctggccctccgggagccagacctg gagaaagtggtgcagtacctagcaggctgtggtctgcaaagctgccttatgcttgtgtct aagggctaccctgatattggctggaaccctgtagaaggggaacgctatttagatttcctc cgctttgctgtgttctgcaatggggaaagtgtggaggaaaatgccaatgtggtggtgagg ctgttgattcgccggccagagtgctttggccccgcccttaggggcgaaggaggaaatggc ttactggcagccatggaggaggccatcaagatctcggaggacccgagcagggatggcccc tcccccacctccgagtccagcaggaccctcgacatagtggatgatgaagaggatgacact atccatatgggaaatgccatcatgaccttctatgctgctctcatagacctgctggggcgc tgtgccccggagatgcatctgatccacgctggaaagggcgaggccatccggatcagggcc atcctgcgctctctgatcccgatcgaagacctggagggggtgatcagcatacccttccca atgcccaccctagccaaagatgggacagtagtggagcctgatatgtcggcgggcttctgt ccggatcacaaggccgccatggtgctgttcctggaccgagtgtatggcatcgaggaccag aacttcctgctgcacctcctggaggtgggcttcctgccggacctccgggcggccgcttcg ctggacacggctgcactgagcgccacagatatggctctggctctgaaccgctacctgtgc accgccgtgctacccctcctgaccaaatgtgcccccctgtttgctggcacggagccctac gcctcgctcatcgactccctgctccacaccgtgtaccgcctgtccaaagggtgctgtctg accaaggcccagcgagacgccattgaagagtgcctgctggccgtgtgcggtaaactgaga ccctccatgatgcagcacctgctcagaaggctggtgtttgatgtccctcttctcaacgag cacacaaaaatgccactgaagttgctgaccaatcactacgagcgttgctggaagtactac tgcctgtctggtggctgggggagttttggagccgcttcggatgaggagctgcacttgtcc agaaaactcttctggggaatattcgacgccttgtctcagaagaggtatgaccaggagctg tttaagctggccctgccctgcctgagtgcagtggcaggagcgctgcccccagactacatg gagtccaactatgtggccatgatggagaagcagtcctccatggacgccgagggcaacttc aacccccagcctgtcgacacctcaaatgtgactgttcctgagaagctggattatttcatc aataaatacgccgaacactctcacgagaagtggtccacagacaagtttgctaatggctgg gttcacggggatcagctgtgtgaggcctccaaagtgcatcctctcctcaaaccttacaaa ggcctgtctgagaaggacaaggaagtgtaccggtggcccattaaagagtctctgaagacc atgttggcctgggggtggagcatcgagaggacgagagagggagacccagcgggactgcac aaccgcgcccgccgaatttctcagtccagtcagctgtccatcgaaggcacacatggcttc agccctcgaccgatcgacatgagcaacgtcaccctgtccagggacctgcactcaatggcc gagctgcttgccgagaactatcataatatttgggcaaagaagaaaaagatagagctggaa gccaaaggaggagggagccatccattattggtgccctatgacactcttactgccaaagag aaatccagagatcgagaaaaagcacaagatatcctcaagttctttcagatcaatggctac gccgtctcaagggctatgaaagagcaggagctggataccccctccatagagaaacgcttc gcctacaccttcctccagcagctcatcgcctatgtagacgaggcacacaaacacatgatg gagtttgatgtaggcacatggggcaaaggagagaagattcctcatgagcagcaaatgaag ttttttgggaaggtggtcctgcccttagtggatcagtatttcaagaatcaccgcctctac ttcctgtctaccgcaatacggcccctcagtagcggaggccacgcctccaacaaggagaag gagatgatcaccagcctgttctgcaaactcggagtacttgtcagacataggatatcactg tttggaaatgattctacctcaatcgtcaactgtcttcatatcctgggccagactctggat gcaaggacggtgatgaagaccggcttggacacagtgaaagcagcattgagggccttcttc gacaacgccgcggaggacttggagaagaccctggagaacctgaagcagggccagttcaca cacaccaagacccagcccaagggggtgacccaaatcatcaactacactacagtggccctt cttcccgtactctcttctctcttcgagcacattgggcagaacctcttcggcgaagacctc atactggatgatgtccaggtgtcctgttacaggattctcaacagcctctactcgcttggc accagcaaaagcatctacgttgaaaggcagcgtccagcactgggagaatgtctggccgca ttctctggagcttttcctgtttcatttttggagccacacctgaacaagtacaacacctac tccatctacaacaccaaaggttcccgcgacagagcagcgctgggtctcccagcccaggtg gaggacatgtcccctctcatcccgtccctggagaagtccctggaggagatcatggagttg gctgagtcgggcatgcgctacacccagatgccccacgtgatggaggtggtgctgcccatg ttgtgcagctacatgtcgcactggtgggagcacgggccagagaacaaccctgagcgggcc gacaagtgctgcacatcgctcacctccgagcacatgaacacactcctgggcaacatcctc aagatcatctacaacaacctgggcattgacgagggcgcctggatgaagcgcctggcagtg ttctctcagccgatcatcagcaaggcgaagccgcagctgctgaagacgcacttcctgccg ctgatggagaagctgaagaagaaggcggcgaccgttctgctggacgaggagcacatgaag gctgagggccggggggagatgtctgaggccgaacttctgattctggacgagttcaccatc ctggtgcgcgacctgtacgccttctacccgctcctcatccgatttgtcgactacaacaga gcgaaatggctcaaggaacccaacccagaggcagaggaactgttccgcatggtggcagaa gttttcatattctgggccaaatctcataatttcaaaagggaggagcagaactttgtggtc cagaacgaaatcaacaacatgtccttcttgatcaccgataccaagtccaaaatgtcgaag ggagccatgtctgaccaagagaggaaaaagatgaagaggaagggggaccgctactccatg cagacctccctgatcgttgctgccctgaagaggctgcttcctgtgggcctgaacatctgc gcccccggggaccaggagctcatcgccctggccaagaaccgcttcacccagaaagacaca gaggatgaggttcgggagatcatccgcaataaccttcacctgcagggcaagctggaggac cctgccattcgatggcagatggccctgtacaaagacctgcccaacaggagcgaggacacc tcagacccagagaaaacggtggagagagtcttagacatcgcccacgtgctgttccatctg gaccaggttgaacacccccagaggagtaagaaggcggtgtggcataagcttctctccaaa cagaggaaaagggctgttgtagcctgttttaggatggctcccctgtataacttacccagg caccgagctgtcaacctcttcctgcagggatacgagaagtcgtggatcgaaacggaggag cattacttcgaagataagctaatagaggatttggctaaaccgggaggtgaggagccgtcg gaagaggacgagggagccaagcggatcgatcctctccaccagcttatccagctcttcagc agaaccgccctgacggagaagtgtaacctggaggaagacaacctgtacatggcctatgct gacatcatggcaaagagctgccacgatgaagaggatgaggatggggaagaggtgaagagc tttgaagagaaagagatggagaaacagaagctgctgtaccagcaggccaggcttcacgat cggggcgcagcggagatggtgctacagaccatcagtgctagcaaaggtgaaatgggacca atggtggcatccacgctgaagctgggtatcgctgtgctgaatggtggaaactccactgtg cagcagaaaatgctggactatctgaaagacaagaaggatgtgggtttcttccagagtctg gcagggctcatgctgtcctgcagcgtgctcgacctcaacgccttcgagaggcagaacaaa gccgaggggctgggcatggtgacggaggagggctcaggggagaaggtgatgcaggatgat gagtttacctgtgacctgtttcgcttcctgcaactattgtgtgaaggacacaattcggat tttcagaattacctgagaacacagacgggaaataacacgactgtcaacatcatcatttca accgttgactaccttctccgagttcaggaatcaatcagtgatttctactggtattactct ggaaaggatgtcatcgatgaacaaggacagcgcaatttctccaaggcaatcaatgtggcc aagcaggtcttcaacaccctcacagagtacatacagggtccatgcactgggaatcagcag agcctggctcatagccggctgtgggatgctgtggtagggttcctccatgtcttcgcacac atgcagatgaagctttcacaggattctagtcaaattgacttattgaaagagctcatggat cttcagaaggacatggttgtaatgctgctgtccatgttggaaggaaatgtggtaaatgga actattggtaagcagatggttgacatgctggtagaatcctcaaacaatgtggagatgatt ctgaaattctttgacatgttcctcaaactgaaagacttgacatcatcagatgccttcaag gagtatgaccctgatgggaagggggtgatctcaaagagagacttccacaaagccatggag agccacaaacattacactcaatccgagaccgagttcctgctctcctgtgcagagacggat gaaaacgaactcttggactatgaggaattcgtagaacgcttccacgaaccagccaaagac attggcttcaatgtggctgtcttattgactaacctgtctgagcacatgcctcacgacaca cggctccagaccttcctggagttggcggagagtgtgctcaactacttccagccttactta ggtcgtatcgagatcatgggtagtgccaaacgcattgagcgggtctactttgagatcagc gagtccagccgcactcagtgggagaagccgcaggtcaaggagtccaagcggcagttcatc ttcgacgtggtcaacgagggcggcgagaaggagaagatggagctcttcgtcaacttctgt gaggacaccatcttcgagatgcagctggcggcccagatgtccgacatcggggagcgatca gccagcaaggaggagagcgagaaggagaaaccagaggaagagaaccctgagatgggcttc ttctcggtgaccacagtaaggacagccctcctcgccctccgctataatgtgatgatgctg atgaaggtgctttccatgaaaagccttaagaagcagatgaagaagatgaagaagatgacg gtgaaggacatggtgaccaccctcatcgccttctactggagcctgctgatgggtctcctc cactttgcctttagcgtgtcgcgtggcttcttccgcattgtctacagcactttcctgggt ggcagcctggtcgagggggccaagaccatgaaggtggccgacctgctggccaacatgccc gaccccacccaggacgaggtccgcggggagggggaggaggccgaaaagaggcattcggac aaggcctcagccgaggaggacctggcggatttggcggtcaatattgaggacaccgacctt ctgtcagacattttcgggcttgacctgaggagggaagggggacagtacaaattgatgcct cacaaccccaacgccagcctagcggatttgctcaacagccccgtgccccctccgccgact ccctcacctgagctccgtagacggcatcaggggcaagggtccacagaggaagaccgagaa ggaaaagaagaaagccagtctgaaccagaaaaggcagagggcgagaatggagaaaaagat gttaagccaaaggatgagaagccaaaacagaaagtcagacagcaccacacctccaaatct gaagagccagagctacaggagtctgccttctggaagaaaatcatcgcttatcagaggaag ctgcttaattattttgcccggaatttctacaacatgagaatgctggctttgtttgttgcc tttgcaatcaacttcatcctgctcttctacaaggtgtccacgtcgtcggcggtggtggag gagaaggaggtggtgtacgcggggccatcagacaccagcgtgaggtggagcccggtggag ggcgtgccccaccgcactgtgacggtgcactttgtcctggaggagagcagtggctacatg gagcccaccctccgcatcctggccatcttacacactgtcatatccttcttctgcatcata gggtactactgcctaaaggtcccgttggtgatatttaaacgcgagaaggaggtagccagg aagttggagttcgacggactctatataacggaacagccgtcagaagatgacattaaaggg caatgggacaggcttgtaattaacacacagtcattcccaaataattactgggacaaattt gtgaaaaggaaggtgatggataaatatggggagttctacggacatgaccgtatcagcgag ctactggggatggacaaggctgccctggacttcagcgacgcacacgagaagaagaaaccc aagaaagacagctcattagttgccgtattgaactccgtcgatgttaagtatcaaatctgg aaattgggagtggtcttcacagacaactccttcctctacctggcctggtacatgaccatg tccatcctggggcactacaataacttcttctttgctgctcacctgctggacatcgccatg gggtttaagaccctgcgcaccatcctgtcctcggtcacccacaacggcaagcagctggtt ctgacggtgggactactggccgtggtggtatacctgtacactgtggtggccttcaacttt ttccgcaaattctacaacaagagcgaggacggagaatctccagacatgaagtgtgacgac atgctcacttgctacatgttccacatgtacgtaggcgtgcgagccggagggggcatcggt gaccagatcgaggatccggcgggagacgagtacgagatttaccggatcatcttcgacatc acgttcttcttcttcgtcatcgtcattctgcttgccatcattcagggtttaataattgat gcctttggtgagctacgtgaccagcaagagcaagtgaaagaggacatggagaccaaatgt ttcatctgcggtatcgggaacgactatttcgacacggtcccccacggcttcgagacgcac acactgcaggagcacaacttggcgaactatctattttttgtgatgtatctcattaacaaa gatgaaacagagcacacaggccaggagtcttacgtctggaagatgtaccaggagcgctgt tgggaattctttccagccggagactgtttccgcaaacaatatgaagaccagctcaactga

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