KEGG   Conger conger (European conger): 133136790
Entry
133136790         CDS       T10633                                 
Symbol
plcb4a
Name
(RefSeq) 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-4 isoform X1
  KO
K05858  phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
Organism
ccog  Conger conger (European conger)
Pathway
ccog00562  Inositol phosphate metabolism
ccog01100  Metabolic pathways
ccog04020  Calcium signaling pathway
ccog04070  Phosphatidylinositol signaling system
ccog04081  Hormone signaling
ccog04082  Neuroactive ligand signaling
ccog04261  Adrenergic signaling in cardiomyocytes
ccog04270  Vascular smooth muscle contraction
ccog04310  Wnt signaling pathway
ccog04371  Apelin signaling pathway
ccog04540  Gap junction
ccog04621  NOD-like receptor signaling pathway
ccog04912  GnRH signaling pathway
ccog04916  Melanogenesis
Module
ccog_M00130  Inositol phosphate metabolism, PI=> PIP2 => Ins(1,4,5)P3 => Ins(1,3,4,5)P4
Brite
KEGG Orthology (KO) [BR:ccog00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00562 Inositol phosphate metabolism
    133136790 (plcb4a)
 09130 Environmental Information Processing
  09132 Signal transduction
   04310 Wnt signaling pathway
    133136790 (plcb4a)
   04371 Apelin signaling pathway
    133136790 (plcb4a)
   04020 Calcium signaling pathway
    133136790 (plcb4a)
   04070 Phosphatidylinositol signaling system
    133136790 (plcb4a)
  09133 Signaling molecules and interaction
   04082 Neuroactive ligand signaling
    133136790 (plcb4a)
   04081 Hormone signaling
    133136790 (plcb4a)
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04540 Gap junction
    133136790 (plcb4a)
 09150 Organismal Systems
  09151 Immune system
   04621 NOD-like receptor signaling pathway
    133136790 (plcb4a)
  09152 Endocrine system
   04912 GnRH signaling pathway
    133136790 (plcb4a)
   04916 Melanogenesis
    133136790 (plcb4a)
  09153 Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    133136790 (plcb4a)
   04270 Vascular smooth muscle contraction
    133136790 (plcb4a)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:ccog04131]
    133136790 (plcb4a)
Enzymes [BR:ccog01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.4  Phosphoric-diester hydrolases
    3.1.4.11  phosphoinositide phospholipase C
     133136790 (plcb4a)
Membrane trafficking [BR:ccog04131]
 Exocytosis
  Calcium ion-dependent exocytosis
   Phospholipases
    133136790 (plcb4a)
 Endocytosis
  Macropinocytosis
   Phospholipase C
    133136790 (plcb4a)
SSDB
Motif
Pfam: PI-PLC-X PH_14 PI-PLC-Y PLCB1-4-like_EFh PLC-beta_C EF-hand_like C2 EF-hand_7 EF-hand_6
Other DBs
NCBI-GeneID: 133136790
NCBI-ProteinID: XP_061110511
LinkDB
Position
1:27153601..27196269
AA seq 1217 aa
MAKAYVFNWQKCIPQFMQEGASFDRYEEDPFVFEPKCFVRVDEFGFFLSWKSEGKEGQVV
ECSLINSIRSAVLPKDPKFLTCLEAPGQAESDLENRIICICSGTDLVNLNFLYLLADSSH
TAKQWTEGLRSLIHNFRANNVCPMTCLNKHWIKLSFLTNVNGKIPVRSITRTFASGKTEK
GIFQALKDLGLPSGKNDEIEHAVFTFDKFYALTQKICPRTDIEELFRKLNGDKSDYLNVD
QLVSFLNDNQRDPRLNEILFPFYDPKRARRIIEMYELDPELRHKGVMSSDGFCRYLMSDE
NAPVFLDHLDLYQDMDQPLAHYFISSSHNTYLNGRQFGGKSIVEMYRQVLLAGCRCVELD
CWDGKGEDQEPIITHGKAMCTDILFKVKIHKQALTQTDVLFKDVIQAIKETAFVSSEYPV
ILSFENHCTKPQQYKMARYCEEIFGDLLLKQTLEAFPLDVGQPLPSPRDLKRKILIKNKR
LKPEVEQKQLEDFKKHMEGNPEDENDEETEIAPTSPVVVDEAHPELKSNGSLSQSTGKKD
SEEEVSDAADMTDISEASDIEISKKGESPEEEEQALIASYKYVGATTSIHPYLSAMINYA
QPVKFQGFSVAEERNIHHNMSSFNESVGLGYLKTNAIEFVNYNKRQMSRIYPKGGRVDSS
NYMPQIFWNAGCQMVALNFQTPDLALQLNQGKFEYNGSCGYLLKPDFMRRPDRMFDPFSE
TPVDGVIAATCSVQVFSGQFLSDKKIGTYVEVDMYGLPTDTIRKEFRTRMVMNNGLNPVY
NEEPFVFRKVILPDLAVLRIGVYDDSNKLIGQRIMPLDGLQTGYRHISLRNEGNKPLSLP
TIFCNIVLKTYVPDGFGAIVDALSDPRKFLSISEKRADQMRAMGIETSDIVDVPSDGTQI
GRANTKRASVTPQSSLELQMSATSGPSTISEAKTGPAGPQVSIDVDELKQMKTYLKLLKK
QQKELLALKRNHAKEQGIRQKSQCTQVDKMVAQHDKDKLTLEKLLEKSIKKKGENNCLEL
RKEIEVKTQAANDNHTTKVKQMVGIHTQEWSEMLRCQSAEEQGLREQHVQQQCTVLKALL
TSHQEQQSQQLKLTHDRQSKEMRANQAKMSMENSKAISQDKTIRNKAERERRVREINSSN
TKKFIEERKRLAMKQSKETEQLQKAQLEQLEKLEKVNEQLVKSHHTKSLCKGQGDATNGE
TGGRDGPQTSHSGMRTM
NT seq 3654 nt   +upstreamnt  +downstreamnt
atggccaaagcctatgtgttcaactggcagaaatgcatcccacagtttatgcaggagggg
gcttcttttgacagatatgaagaggatccctttgtctttgagccaaagtgtttcgtcaga
gtggacgagtttgggttctttctgtcatggaaaagcgaagggaaggaaggccaggttgta
gagtgctccctcatcaactccatccgcagtgctgttctacccaaggacccgaagttcctg
acgtgcctggaggctccaggacaagctgagagtgacttggagaacagaatcatctgcatc
tgcagtggaactgacctggtcaacctgaacttcctgtacctactggcagacagcagccac
actgccaagcaatggacggagggcctcaggtccttgattcacaacttcagagcaaacaac
gtgtgtccaatgacctgcctgaataaacattggatcaagctgtcatttttgaccaatgtg
aatggaaagattcctgtccgaagcataaccaggacatttgcctctggaaaaacagaaaag
gggatcttccaggcactcaaggacctgggcctgcccagtgggaagaacgatgaaattgag
cacgccgtcttcacctttgacaagttttacgccctcacccagaagatctgcccgcggacc
gacatcgaggagcttttccggaaactaaacggtgacaaaagtgattatttaaatgtagac
cagttagtcagctttctgaacgacaaccaacgggatcctcgtttgaatgagatcctgttt
ccattttatgatccgaaacgagctcggcggatcatagagatgtatgagctggacccagaa
ctcaggcataaaggtgtgatgtcttctgacgggttctgccggtacctcatgtcggacgag
aacgctccggtgttcctcgaccatctggatctgtaccaggatatggaccaaccattggct
cactacttcatcagctcctcccacaatacatatctgaacggccggcagtttggtggaaag
tccattgtggaaatgtaccggcaggtgctcctggcagggtgcaggtgtgtggaactggac
tgttgggatggaaaaggagaagaccaggagccgattattacccacgggaaagccatgtgc
actgacatcctcttcaaggtgaaaatacacaagcaagcactcacacagactgacgtcctc
ttcaaggatgtaattcaagccattaaagaaacggcttttgtgtcatctgagtaccctgtg
attctgtcattcgaaaaccactgcacgaagccacagcagtataagatggctcgttactgt
gaggagatctttggcgatctacttctcaaacagacactggaggcattcccgctagatgtg
ggccagcctttaccctcccccagagacctgaaaaggaaaatactcatcaagaacaagcga
ttaaaacctgaagtagaacagaaacagctggaggactttaaaaagcacatggaaggaaac
ccggaggacgagaatgatgaggagactgaaattgctcccacgtctcctgtcgtggtggat
gaggcccacccggagttgaagtcaaatggcagtctgagccaaagcacagggaaaaaggat
tctgaagaagaagtttcagatgcagcagacatgactgatatatctgaggcctctgatata
gaaattagcaagaagggtgaaagccctgaagaagaggagcaggctttgattgcttcctac
aagtatgtaggggccaccaccagcatccacccttatctgtcagccatgattaactacgcc
cagcctgtcaagttccagggcttcagtgtggctgaagaaaggaatatccaccataacatg
tcgtccttcaatgaatcggttggcctggggtacttgaagacaaacgccattgaatttgtg
aactacaacaaacgacagatgagccgtatctatcctaaagggggcagggtggactccagt
aattacatgcctcagatcttctggaatgccggctgccagatggtggccctcaacttccag
accccagatttagccttgcagctgaaccaaggaaagtttgagtacaatggctcttgtggg
tacctgctgaagccagacttcatgcgtcgcccagacagaatgtttgaccctttctctgaa
acccctgtagatggcgtcattgctgctacgtgcagcgttcaagtgttctcaggacagttc
ctgtctgataagaagatcggcacatacgtggaagtggacatgtatgggttgcccacagac
accattcgcaaggagttccgcaccaggatggtgatgaacaacgggctgaaccctgtttac
aacgaggagcccttcgtctttaggaaggtaatcctaccggacctggcggtgctgaggatc
ggtgtgtacgacgacagcaacaagctgataggccagcggatcatgcccctggacggcttg
cagactgggtacagacacatctccctgaggaacgaggggaacaagcctctgtctctgccc
accatcttctgcaacatcgtcctcaaaacatacgtgcccgatggcttcggggccattgtt
gatgcactctccgaccccagaaaattcctctccatctcggagaagagagcggatcagatg
agggccatgggtatcgagacgagtgacattgtggatgtgcccagtgacggcacacagatt
ggcagagcgaacacgaaaagggccagcgtgactccgcagtccagcttagagctgcagatg
agtgccacatctggaccaagcaccatcagcgaggccaagactgggccggctggcccccag
gtcagcattgatgtggatgaactgaaacagatgaagacatatcttaaactcctgaagaaa
caacagaaagagctgcttgccttaaaaagaaatcatgcaaaggaacagggaatccgacag
aaatctcagtgcactcaggtagacaagatggtggcccagcatgacaaagacaaactgact
ctggaaaagctactggaaaaatctattaagaaaaagggagaaaacaactgccttgaactg
agaaaggaaattgaagtgaaaacccaggcagccaacgataatcacacaacaaaggtgaag
cagatggtggggatccatacccaggagtggtctgagatgttgaggtgtcagagtgcagag
gaacaggggttgagagagcagcacgttcagcagcagtgcaccgtcctcaaggccctgctg
accagccaccaggagcagcagtcccagcagctcaaactcacccatgacaggcagagcaaa
gagatgcgtgccaaccaggccaagatgtccatggaaaacagcaaagccatcagccaggac
aagaccatcagaaacaaggcagagagagagaggcgagttcgggaaataaacagcagtaac
actaagaagttcatcgaggagagaaaaaggctggccatgaaacagtcaaaggagacggag
cagcttcagaaagctcagctggaacagcttgagaagctggagaaggtcaatgagcagctt
gtgaaatcacatcatacaaagtctctgtgtaaaggccaaggagatgcaacaaatggtgaa
actggaggcagagatggacctcagaccagccacagtggtatgaggaccatgtga

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