Crocuta crocuta (spotted hyena): 144219588
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Entry
144219588 CDS
T11532
Symbol
ATP2A3
Name
(RefSeq) sarcoplasmic/endoplasmic reticulum calcium ATPase 3 isoform X1
KO
K05853
P-type Ca2+ transporter type 2A [EC:
7.2.2.10
]
Organism
ccru Crocuta crocuta (spotted hyena)
Pathway
ccru04020
Calcium signaling pathway
ccru04022
cGMP-PKG signaling pathway
ccru04024
cAMP signaling pathway
ccru04148
Efferocytosis
ccru04260
Cardiac muscle contraction
ccru04261
Adrenergic signaling in cardiomyocytes
ccru04380
Osteoclast differentiation
ccru04919
Thyroid hormone signaling pathway
ccru04972
Pancreatic secretion
ccru05010
Alzheimer disease
ccru05017
Spinocerebellar ataxia
ccru05022
Pathways of neurodegeneration - multiple diseases
ccru05410
Hypertrophic cardiomyopathy
ccru05412
Arrhythmogenic right ventricular cardiomyopathy
ccru05414
Dilated cardiomyopathy
ccru05415
Diabetic cardiomyopathy
Brite
KEGG Orthology (KO) [BR:
ccru00001
]
09130 Environmental Information Processing
09132 Signal transduction
04020 Calcium signaling pathway
144219588 (ATP2A3)
04024 cAMP signaling pathway
144219588 (ATP2A3)
04022 cGMP-PKG signaling pathway
144219588 (ATP2A3)
09140 Cellular Processes
09141 Transport and catabolism
04148 Efferocytosis
144219588 (ATP2A3)
09150 Organismal Systems
09152 Endocrine system
04919 Thyroid hormone signaling pathway
144219588 (ATP2A3)
09153 Circulatory system
04260 Cardiac muscle contraction
144219588 (ATP2A3)
04261 Adrenergic signaling in cardiomyocytes
144219588 (ATP2A3)
09154 Digestive system
04972 Pancreatic secretion
144219588 (ATP2A3)
09158 Development and regeneration
04380 Osteoclast differentiation
144219588 (ATP2A3)
09160 Human Diseases
09164 Neurodegenerative disease
05010 Alzheimer disease
144219588 (ATP2A3)
05017 Spinocerebellar ataxia
144219588 (ATP2A3)
05022 Pathways of neurodegeneration - multiple diseases
144219588 (ATP2A3)
09166 Cardiovascular disease
05410 Hypertrophic cardiomyopathy
144219588 (ATP2A3)
05412 Arrhythmogenic right ventricular cardiomyopathy
144219588 (ATP2A3)
05414 Dilated cardiomyopathy
144219588 (ATP2A3)
05415 Diabetic cardiomyopathy
144219588 (ATP2A3)
Enzymes [BR:
ccru01000
]
7. Translocases
7.2 Catalysing the translocation of inorganic cations
7.2.2 Linked to the hydrolysis of a nucleoside triphosphate
7.2.2.10 P-type Ca2+ transporter
144219588 (ATP2A3)
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
Cation_ATPase
Cation_ATPase_C
E1-E2_ATPase
Hydrolase
Hydrolase_3
HAD
Cation_ATPase_N
TNP-like_RNaseH_N
DUF3106
Motif
Other DBs
NCBI-GeneID:
144219588
NCBI-ProteinID:
XP_077605730
LinkDB
All DBs
Position
Unknown
AA seq
1030 aa
AA seq
DB search
MSLGHSLSGCVLPSPQQRDTVLSTPVSPTCASRASGSQPLNGREGVGQMVSEAVSALNGG
ESLGKGPRLHIVLRFSGKSLWELVLEQFEDLLVRILLLAALVSFVLAWFEEGEETTTAFV
EPLVIILILVANAIVGVWQERNAESAIEALKEYEPEMGKVIRSDRKGVQRVRARDIVPGD
IVEVAVGDKVPADLRLIEIKSTTLRVDQSILTGESVSVTKHTDVILDPRAVNQDKKNMLF
SGTNIASGKALGVAVATGLRTELGKIRSQMAAVEPERTPLQQKLDEFGRQLSRAISVICV
AVWVINISHFADPAHGGSWLRGAVYYFKIAVALAVAAIPEGLPAVITTCLALGTRRMARK
NAIVRSLPSVETLGCTSVICSDKTGTLTTNQMSVCRMFVVAEAQASSCRLHEFTISGTTY
APEGEVRQAEQLVRCGQFDGLVELATICALCNDSALDYNEAKGVYEKVGEATETALTCLV
EKMNVFDTNLEALSQVERASACNAVIKQLMRKEFTLEFSRDRKSMSVYCTPTRPGLAAQG
SKMFVKGAPESVIDRCSSVRVGSRTVPLNTTSREQILAKIRDWGSGSDTLRCLALATRDA
PPRKEDMQLDDCSKFAQYETDLTFVGCVGMLDPPRPEVAACIERCHQAGIRVVMITGDNK
GTAVAICRRLGIFKDTEDVVGKAYTGREFDDLSPEQQRQACRTACCFARVEPAHKSRIVE
NLQSFNEITAMTGDGVNDAPALKKAEIGIAMGSGTAVAKSAAEMVLSDDNFASIVAAVEE
GRAIYNNMKQFIRYLISSNVGEVVCIFLTAILGLPEALIPVQLLWVNLVTDGLPATALGF
NPPDLDIMEKLPRNPREALISGWLFFRYLAIGVYVGLATVAAATWWFLYDAEGPHVTFYQ
LRNFLKCSKDNPLFADIDCEVFESRFPTTMALSVLVTIEMCNALNSVSENQSLLRMPPWL
NPWLLGAVVMSMALHFFILLVPPLPLIFQVTPLSGRQWVVVLQISLPVILLDEALKYLSR
HHVDEEKDKK
NT seq
3093 nt
NT seq
+upstream
nt +downstream
nt
atgtccttgggccattcactgtcaggttgtgtccttccctctccccaacagagagatact
gtgctgagcaccccagtatcacccacctgtgcctctagggcctcaggctctcagcctttg
aatggtagggagggagtgggccagatggtttctgaggcggtctcagctctgaatgggggc
gagtcactgggtaagggacccaggcttcacatagtgctccggttctcagggaagtccctg
tgggagctggtgctggagcagtttgaagacctgctggtgcgcatcctgctgttggctgcc
ctggtctccttcgtcctggcctggtttgaggagggcgaggagaccacaacagccttcgtg
gagcccctggtcatcattctgatcctcgtggccaatgccatcgtgggcgtatggcaggaa
cgcaacgctgagagtgccattgaggccctgaaggagtatgagcctgagatgggtaaggtg
atccgctcagaccgcaagggcgtgcagagggtccgtgcccgggacattgtccctggagac
atcgtggaggtagcagtgggagacaaggtgcccgctgacctccgcctcatcgagatcaag
tccaccaccctgagagtggaccagtccatcttgacaggtgaatccgtgtctgtgaccaaa
cacacagacgttatcctggatcccagagctgtgaaccaggacaagaagaacatgctgttc
tctggtaccaacatcgcatcgggcaaggcactgggggtggcggtggccacaggcctgcgc
acagagctgggtaagatccgcagccagatggcggcagtggagccagagcggacaccactg
cagcaaaagctggacgagtttgggcggcagctgtcccgtgccatctctgtgatctgtgtg
gccgtgtgggtcatcaatatcagccacttcgctgacccagcccatggtggctcgtggctc
cgtggtgccgtctactacttcaagattgctgtggccctcgctgtggctgccatccctgag
ggcctcccagctgtcatcactacatgcctggctctgggcacacggcgcatggcacgcaag
aatgccattgtgcggagcctgccctctgtggagaccttgggctgcacctcggtcatctgc
tccgacaagacaggcaccctcaccaccaatcagatgtccgtgtgccggatgttcgtggta
gctgaggcccaagcaagctcctgccgtttgcacgagttcaccatctcgggtaccacttat
gccccggagggcgaagtgaggcaggcggagcagcttgtgcgctgtgggcagttcgatggt
ctggtggagctggcgacaatctgtgccctgtgcaatgactcagcgctggattacaatgag
gctaagggcgtatatgagaaggtgggagaggccacagagacggccctgacttgcctggtg
gagaaaatgaacgtgtttgacaccaaccttgaggccctgtcccaggtggaacgagccagt
gcttgcaatgcggtcattaagcagctgatgcggaaggagtttactttggagttctcccga
gaccggaagtccatgtcagtgtactgcacacccactcgacctggcctggcagcccagggc
agcaagatgtttgtcaagggggctcctgagagtgtgatcgaccgctgcagctcagtccga
gtgggaagccgcacggtacccctgaacaccacctccagggagcagatcctggccaagatc
cgggattggggctctggctcagacacgctgcgttgcctggcactggccactcgggatgct
cccccaaggaaggaggacatgcagctggatgactgcagcaagtttgctcagtacgagacg
gacctgacctttgtgggctgcgtgggcatgctggaccctccaaggcccgaggtggctgct
tgcatcgaacgctgccaccaggctggcatccgtgtggtcatgatcacgggggacaacaaa
ggcacagctgtggccatttgccgccggcttggcatcttcaaggacacagaggatgtggtg
ggcaaggcctacacagggcgcgaatttgatgacctcagccccgagcagcagcgccaggcc
tgccgcacggcatgctgcttcgcccgtgtggaacctgcacacaagtctcgaatcgtagag
aacctacagtccttcaatgagatcactgccatgactggagacggcgtgaatgatgccccg
gctctgaagaaagcagagattggcattgccatgggctctggcacagctgtggccaagtca
gcagccgagatggtgctgtcagatgacaactttgcctcaattgtggctgcagtggaggag
ggccgggccatctacaacaacatgaagcaattcatccgctacctcatctcttccaatgtc
ggcgaggttgtctgcatcttcctcacggcaatcctgggcctgccagaagctctgatccct
gtgcagctgctctgggtgaacctggtgacagatggcttgcctgccacagccctgggtttc
aacccaccagacctggacatcatggagaagctgcctcgaaaccctcgtgaggccctcatc
agtggctggctcttttttcgatatctggctattggagtgtacgtaggcctggccacggtg
gctgccgccacctggtggttcctatatgatgccgagggacctcacgtcaccttctaccag
ctgaggaacttcctgaagtgctccaaggacaaccctctctttgccgacattgactgcgag
gtcttcgagtcacgcttcccgacaaccatggccttgtctgtgctggtgaccattgaaatg
tgcaatgcactcaacagcgtctcggagaaccagtcgttgctgcggatgccaccctggctg
aacccttggctgctgggagccgtggtcatgtccatggccctgcatttcttcatcctgctg
gtgccacccctgccccttattttccaggtgacccccctgagtgggcgccagtgggtagtg
gtgctccagatatctctgcctgtcatcctgcttgatgaggccctcaagtacctgtcccgg
caccacgtggatgaagaaaaggacaagaagtga
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