Crocuta crocuta (spotted hyena): 144220375
Help
Entry
144220375 CDS
T11532
Symbol
NSD2
Name
(RefSeq) histone-lysine N-methyltransferase NSD2
KO
K11424
[histone H3]-lysine36 N-dimethyltransferase NSD2 [EC:
2.1.1.357
]
Organism
ccru Crocuta crocuta (spotted hyena)
Pathway
ccru00310
Lysine degradation
ccru01100
Metabolic pathways
ccru05202
Transcriptional misregulation in cancer
Brite
KEGG Orthology (KO) [BR:
ccru00001
]
09100 Metabolism
09105 Amino acid metabolism
00310 Lysine degradation
144220375 (NSD2)
09160 Human Diseases
09161 Cancer: overview
05202 Transcriptional misregulation in cancer
144220375 (NSD2)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03036 Chromosome and associated proteins [BR:
ccru03036
]
144220375 (NSD2)
Enzymes [BR:
ccru01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.1 Methyltransferases
2.1.1.357 [histone H3]-lysine36 N-dimethyltransferase
144220375 (NSD2)
Chromosome and associated proteins [BR:
ccru03036
]
Eukaryotic type
Histone modification proteins
HMTs (histone methyltransferases)
HKMTs (histone lysine methyltransferases)
144220375 (NSD2)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
PWWP
SET
C5HCH
AWS
PHD_NSD
HMG_box
PHD-1st_NSD
PHD
PHDvar_NSD
HMG_box_2
zf-HC5HC2H
zf-HC5HC2H_2
MUM1-like_PWWP
HMG_WDHD1
Motif
Other DBs
NCBI-GeneID:
144220375
NCBI-ProteinID:
XP_077606712
LinkDB
All DBs
Position
Unknown
AA seq
1359 aa
AA seq
DB search
MKQAPEILGSPNSKAQGCEVNRECSVFLSKAQLSSSLQEGVVQKFNGHDALPFIPSEKLK
DLTSRVFNGEPGAHDAKLRFEPQEVKALGTPPSTTPTKNGSPEIKLKITKTYMNGKPLFE
SSICGDGAAAVSQSEENGQKPENKARRNRKRSIKYDSLLEQGLVEAALASRISSPSDKKI
AAKKESCPNTGRDKDHLLKYSVGDLVWSKVSGYPWWPCMVSADPLLHNYTKLKGQKKSAR
QYHVQFFGDAPERAWIFEKSLVAFEGEGQFEKLCQESAKQAPTKAEKIKLLKPISGKLRA
QWEMGIVQAEEAASMSVEERKAKFTFLYVGDQLHLNPHVAKEAGISVEPPPPGQMLEPSG
VPEEAAADPTSMREEGIPIKRRRRVKLASSAETRASDPETVQSTPQKMAEADPKRGVGSP
PGRKKATASAPRSRKGDAAAQFLVFCQKHRDEVVAEHPDASAEEIEELLASQWNMLNEKQ
KARYHTKFALVASPQAEEDSGNVNGKKRNQAKRTQDPPEDVDIEDAPRKRLRTDKHGLRK
RETTSDKMARTGSCKALEAASPLKSQAATKHLSDACKPLKKRNRASAAASSTPFSKSSSP
SASLTENEVSDGPGDEPAESPYESADEAQTEVSVSSKKSERGVAAKKEYVCQGAGQPAGP
DPAPWLGSCARERPARHGRVTRTLPERVRSGGDGGGRHXLAAAALTGIHSCFVCKESQMD
VRRCVVSQCGKFYHEACVRKYPLTVFESRGFRCPLHSCLSCHASNPSNPRPSKGKMMRCV
RCPVAYHGGDACLAAGCSVIASNSIICSGHFTARKGKRHHAHVNVSWCFVCSKGGSLLCC
ESCPAAFHPDCLSIEMPDGSWFCNECRAGKRLHFQDVVWVKLGNYRWWPAEVCHPKNVPP
NIQKMKHEIGEFPVFFFGSKDYYWTHQARVFPYMEGDRGSRYQGVRGIGRVFKNALQEAE
ARFREIKLQREARETQESERKPPPYKHIKVNKPYGKVQIYTADISEIPKCNCKPTDENPC
GFDSECLNRMLMFECHPQVCPAGEHCQNQHFTKRQYPETKVVKTAGKGWGLVAKRDIRKG
EFVNEYVGELIDEEECMARIKHAHENDITHFYMLTIDKDRIIDAGPKGNYSRFMNHSCQP
NCETLKWTVNGDTRVGLFAVCDIPAGTELTFNYNLDCLGNEKTVCRCGASNCSGFLGDRP
KTSTSLSSEEKGKKTKKRTRRRRTRGEGKKESEDECFRCGDGGQLVLCDRKSCTKAYHLS
CLGLGKRPFGKWECPWHHCDVCGRPSTSFCHFCPNSFCKQHQDGAVLGSTRDGRPCCREH
DLGAAPARSAQTGKPFLEPSKSKGKRKKRRCWRRVTEGK
NT seq
4080 nt
NT seq
+upstream
nt +downstream
nt
atgaagcaggcaccagagatccttggcagcccaaacagcaaggcgcagggctgtgaagtg
aaccgcgagtgctctgtgttcctcagcaaagcccagctctctagcagcctccaggagggc
gtcgtgcagaagttcaacggccacgacgcacttccctttattccatccgagaagctgaag
gacctcacgtcccgtgtatttaatggcgaacctggtgctcatgatgccaaattgcgcttt
gagccccaggaagtaaaggcgctcgggacgccgcccagcaccaccccgaccaaaaacggc
tctccggaaattaagttgaagatcaccaaaacgtacatgaatgggaaacctctctttgaa
tcttcaatttgtggggacggtgctgccgccgtgtcccagtcagaagaaaatggacaaaaa
ccagaaaataaggccagaaggaacaggaagaggagcataaaatatgactccttgctggag
cagggtcttgttgaagcggcactggcatccaggatctcgagtccttcggataagaagatt
gccgctaagaaagagtcctgtccgaatactggcagagacaaagaccacctgctgaaatac
agtgttggcgacttggtgtggtccaaagtgtccggttacccttggtggccgtgcatggtc
tctgctgacccgctccttcacaactataccaaacttaaaggtcagaaaaagagtgcacgc
cagtatcacgtacaattctttggtgatgccccagaaagagcttggatatttgagaagagc
cttgtagcttttgaaggagaaggacagtttgaaaaattatgccaggaaagtgccaagcag
gcacccacgaaagctgagaaaattaagctgttgaaacctatttcagggaagttgagggcc
cagtgggaaatgggcatcgttcaagctgaagaagccgcaagcatgtcagtggaggagcgg
aaagccaagttcactttcctctacgtgggggaccagcttcatctcaaccctcacgtagct
aaggaggcaggcatttctgtggagcctccgcctccgggacagatgctagaaccctcagga
gtccctgaagaagctgccgctgaccccacgtccatgcgagaagagggcattcccatcaag
agaaggcggagagtgaagctggctagctctgccgaaacccgagcaagtgaccctgagaca
gtacagagtactccccaaaagatggcagaggccgaccccaagagaggagtcgggtctcct
cctgggaggaagaaggccacggcttccgctccgcgaagcagaaagggagacgcggcggcc
cagtttctggtcttctgtcagaagcacagggatgaggtggtggcggagcaccctgacgcc
tcggccgaggagatcgaagagctgctcgcgtcgcagtggaacatgctgaacgagaagcag
aaggcgcgctatcacaccaagttcgccctggtggcctctccccaggctgaagaagactct
ggtaacgtaaatgggaaaaaaagaaaccaggcaaagaggacacaggaccctcctgaagat
gttgacattgaagacgctccccggaagagactcaggaccgacaagcatggtctccggaag
agagagacgacgagtgacaagatggcccggacaggctcttgcaaggccctggaggctgcc
tccccgctgaagagccaggcagcaacgaaacatctgtctgatgcatgcaaaccactgaag
aagcgaaatcgggcgtctgcagcggcgtcgtccactccttttagcaaaagttcatctcct
tctgcatccttaactgagaatgaggtgtcggacggcccgggagacgagcccgcggagtcc
ccgtacgagagcgccgacgaagcccagaccgaggtgtccgtgtcctccaagaagtccgag
cggggcgtggccgccaaaaaggagtacgtgtgtcagggagccgggcagccggcggggccg
gacccagcgccctggctgggctcgtgcgcccgtgagaggcctgcacgacacggccgtgtc
acgcgcacgcttcccgaacgcgtgaggtcgggtggggacgggggagggcggcaccanctg
gcggccgcggccctgacggggattcactcgtgttttgtgtgtaaggagagccagatggac
gtcaggcgctgtgttgtgtcgcagtgtgggaagttttaccacgaagcgtgcgtgaggaag
tacccgctgaccgtgttcgagagccgaggcttccgctgccccctgcacagctgcctgagc
tgccacgcgtccaacccttccaaccccaggccgtctaaagggaagatgatgcggtgcgtc
cgctgccccgtcgcctaccatggaggggatgcctgtctggcggccggctgctcggtgatc
gcctccaacagcatcatctgcagcggccacttcaccgcgcgcaaggggaagaggcatcac
gcccacgtgaacgtgagctggtgcttcgtgtgctccaaagggggaagcctgctgtgctgc
gagtcctgcccggcggccttccaccccgactgcctgagcatcgagatgccggacggcagc
tggttctgcaacgagtgccgtgcggggaagcggctgcacttccaggacgtcgtctgggtt
aaactggggaactacagatggtggccggcagaagtttgccatcccaaaaatgttccccca
aatattcagaaaatgaagcacgagattggagaattccctgtgtttttctttgggtctaaa
gattattactggacgcatcaggcgcgagtgttcccgtacatggagggggaccggggcagc
cgctaccagggggtcagaggaatcggaagagtcttcaaaaacgcgctgcaggaagctgaa
gctcgttttcgcgaaatcaaacttcaaagggaagccagagaaacgcaggagagtgagcgc
aagcctcccccgtacaagcacatcaaggtgaacaagccgtacgggaaagtccagatctac
acggcggacatctctgagatccccaagtgcaactgtaagcccacagacgagaacccctgt
ggcttcgactccgagtgcctgaaccggatgctgatgttcgagtgccacccgcaggtgtgc
cccgcaggcgagcactgccagaaccagcacttcaccaagcgccagtaccccgagaccaag
gtcgtcaagaccgctggcaaagggtggggcctggtggccaagcgggacatcaggaaggga
gagttcgtgaacgagtacgtcggtgagctgattgacgaggaggagtgcatggccaggatc
aagcacgctcatgagaacgacatcacgcacttctacatgctcaccatagacaaggaccgg
ataattgatgccggccccaaaggaaactactcccgattcatgaaccacagctgccagccc
aactgtgagaccctcaagtggacggtgaacggggacactcgcgtgggcctgtttgccgtg
tgtgacatccccgcagggacagagctgacctttaactacaacctcgactgtttgggtaac
gagaagacagtctgtcggtgcggggcctccaactgcagcgggttccttggggacagacca
aagacctcaacatccctttcttcagaggaaaagggcaaaaagaccaagaaaagaacgagg
aggcggagaaccagaggcgaagggaagaaggaatctgaggacgagtgtttccgctgtggg
gacggcggccagctggtgctgtgtgaccgcaagtcctgcaccaaggcctatcacctgtcg
tgcctgggtctgggcaagcggcccttcggcaagtgggagtgcccctggcatcactgtgac
gtgtgcggcaggccttccacgtccttctgccacttctgccccaattcgttctgcaagcag
caccaggacggggcggtcctcggctccacgcgggacgggcggccgtgctgccgcgagcac
gacctgggggccgcgccggctcggagcgcccagactgggaagccctttctggaacccagc
aagtccaaggggaagagaaagaaaaggaggtgctggcggagggtcacggaaggcaaatag
DBGET
integrated database retrieval system
