Crocuta crocuta (spotted hyena): 144222013 Help Entry 144222013         CDS       T11532                                  Symbol ITGA2 Name (RefSeq) integrin alpha-2   KO K06481   integrin alpha 2 Organism ccru  Crocuta crocuta (spotted hyena) Pathway ccru03271   Virion - Rotavirus ccru04145   Phagocytosis ccru04151   PI3K-Akt signaling pathway ccru04510   Focal adhesion ccru04512   ECM-receptor interaction ccru04518   Integrin signaling ccru04611   Platelet activation ccru04640   Hematopoietic cell lineage ccru04810   Regulation of actin cytoskeleton ccru04820   Cytoskeleton in muscle cells ccru05165   Human papillomavirus infection ccru05200   Pathways in cancer ccru05205   Proteoglycans in cancer ccru05222   Small cell lung cancer ccru05410   Hypertrophic cardiomyopathy ccru05412   Arrhythmogenic right ventricular cardiomyopathy ccru05414   Dilated cardiomyopathy Brite KEGG Orthology (KO) [BR:ccru00001]  09120 Genetic Information Processing   09125 Information processing in viruses    03271 Virion - Rotavirus     144222013 (ITGA2)  09130 Environmental Information Processing   09132 Signal transduction    04151 PI3K-Akt signaling pathway     144222013 (ITGA2)   09133 Signaling molecules and interaction    04512 ECM-receptor interaction     144222013 (ITGA2)    04518 Integrin signaling     144222013 (ITGA2)  09140 Cellular Processes   09141 Transport and catabolism    04145 Phagocytosis     144222013 (ITGA2)   09144 Cellular community - eukaryotes    04510 Focal adhesion     144222013 (ITGA2)   09142 Cell motility    04820 Cytoskeleton in muscle cells     144222013 (ITGA2)    04810 Regulation of actin cytoskeleton     144222013 (ITGA2)  09150 Organismal Systems   09151 Immune system    04640 Hematopoietic cell lineage     144222013 (ITGA2)    04611 Platelet activation     144222013 (ITGA2)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     144222013 (ITGA2)    05205 Proteoglycans in cancer     144222013 (ITGA2)   09162 Cancer: specific types    05222 Small cell lung cancer     144222013 (ITGA2)   09172 Infectious disease: viral    05165 Human papillomavirus infection     144222013 (ITGA2)   09166 Cardiovascular disease    05410 Hypertrophic cardiomyopathy     144222013 (ITGA2)    05412 Arrhythmogenic right ventricular cardiomyopathy     144222013 (ITGA2)    05414 Dilated cardiomyopathy     144222013 (ITGA2)  09180 Brite Hierarchies   09183 Protein families: signaling and cellular processes    04147 Exosome [BR:ccru04147]     144222013 (ITGA2)    04515 Cell adhesion molecules [BR:ccru04515]     144222013 (ITGA2)    04090 CD molecules [BR:ccru04090]     144222013 (ITGA2) Exosome [BR:ccru04147]  Exosomal proteins   Exosomal proteins of colorectal cancer cells    144222013 (ITGA2)   Exosomal proteins of bladder cancer cells    144222013 (ITGA2) Cell adhesion molecules [BR:ccru04515]  Integrins   Integrin alpha subunits    144222013 (ITGA2) CD molecules [BR:ccru04090]  Proteins   144222013 (ITGA2) SSDB OrthologParalogGFIT Motif Pfam:  VWA FG-GAP Integrin_A_Ig_2 Integrin_A_Ig_3 VWA_2 FG-GAP_3 FG-GAP_2 vWA_SIBA-E HisK_sensor ITGAX-like_Ig_3 Integrin_alpha Motif Other DBs NCBI-GeneID:  144222013 NCBI-ProteinID:  XP_077608627 LinkDB All DBs Position Unknown AA seq 1178 aa AA seqDB search MRPGWTGGAPLLVLLLSQGILKCCMAYNIGLLGAKIFSGPSSEQFGYAVQQFINPKGNWL LVGSPWSGFPENRMGDVYKCPIDLSTATCEKLNLETATTIPNVTEMKTNMSLGLTLTRNV GTGGFLTCGPLWAQQCGSQYYATGVCSDISPDFQLLASFAPAVQTCPSLIDVVVVCDESN SIYPWEAVKNFLEKFVQGLDIGPTKTQVGLIQYANNPRVIFNLNTFKTKDAMIEATSRTY QFGGDLTNTFKAIQYAKDFAYKAAAGGRPGATKVMVVVTDGESHDGSMLKAVIDECNNDN ILRFGIAVLGYLNRNALDTKNLIKEIKAIASIPTERYFFNVSDEAALLEKAGTLGEQIFS IEGTIQGGDNFQMEMSQVGFSADYSPQKDILMLGAVGAYAWSGTVVQQTSHGHLIFPKQA FDQILQDKNHSSYLGYSVATISTGKGVHFVAGAPRANYTGQIVLYRVNESGNVTIIQAHR GDQIGSYFGSVLCSVDVNKDSVTDVLLVGAPMYMNDLKKEEGRVYLFTITKGILNWHQFL EGPDGVENSRFGSAIAALSDINMDGFNDVIVGSPLENQNSGAVYIYNGHEGTIHREYSQK ILGSDGAFRSHLQYFGRSLDGYSDLNGDSITDVSIGAFGQVVQLWSQSIADVSVNASFTP EKITLFNKNADIKLKLCFSAKFRPTKQNSQVAITYNITIDADLYSSRVTSRGLFKENNER CLQKNMTVSQTQSCSEYIIHIQKPSDVVSSLDLCVNISLENPGTSPALEAYSEKAKVFSI PFYKDCGDDGVCSSDLVLDVQQLSAAQDQPFIVSNQNKRLTFSVMLKNKRESAYNTGIVI DFSENLFFASWTMPVDGTEVICQIASSQKSVTCDVGYPALKRQQQVTFMINFDFNLQNLQ NQASLNFQALSESSEENKADNLVNFKIPLLYDADIHITRSTNINFYEVSSDGNIPSIVHS FEDIGPKFIFSVKVTTGSIPVSMASMIIHIPQYTKEKNPLMYVTGVHTDQAGDISCNAEI NPLKIGHTASSVSFNSENFRHIKELNCRSASCSNVTCWLKDLQVKREYFLNVSTRIWNGT FAASTFQTVQLTASAEIDTYNPQIYVIEENTVTIPITIMKPHEKAEVPTGVIVGSVIAGI LLLLALVAVLWKLGFFKRKYEKMSKTADEIDETTELNS NT seq 3537 nt NT seq  +upstreamnt  +downstreamnt atgcggccaggatggacggggggcgcgcccttgctggtgttactgctcagtcaaggcatt ttaaaatgttgtatggcatacaatatcggtctcctaggagcaaagatattttccggtcct tcaagtgaacagtttggctatgctgtgcagcagtttataaatccaaaaggcaactggtta ctagttggttcaccttggagtggctttcctgagaacagaatgggagacgtgtataaatgt cctatagatctgtccactgctacatgtgaaaaactgaatctggaaactgctacaaccatt cccaacgttaccgaaatgaaaaccaacatgagccttggcttgacactcacaaggaacgta ggaaccggaggatttctcacgtgcggtcccctgtgggcacagcagtgcggaagccagtat tatgcaactggtgtttgttctgatatcagtcccgattttcagctcttggccagctttgca cctgcagttcagacctgcccttctctcatagatgttgtggttgtatgtgatgagtcaaac agtatttatccctgggaagcagtaaagaattttttggaaaaatttgtccaaggcctggat ataggccccacaaagacacaggtggggttaattcagtatgccaacaatccaagagttata tttaacctgaacactttcaaaaccaaagatgcaatgattgaagcaacatcccggacatac caatttggtggagatctcacaaatacattcaaagcaattcaatacgcaaaagattttgct tataaggcagctgccggaggacgaccaggtgctaccaaagtaatggtggttgtaactgat ggtgaatcgcatgatggttccatgttgaaggccgtgattgatgaatgcaacaatgacaat atattgaggtttggcatagcggttcttgggtacttaaacagaaatgcccttgacactaaa aatttaataaaagaaattaaagcaattgccagtattccaacagaaagatattttttcaat gtgtctgatgaagcagctctactagaaaaggctggtacactcggagaacaaatttttagc attgaaggtactattcaaggaggggacaacttccagatggaaatgtcacaagtgggattc agcgcagattactctcctcaaaaggatattctgatgctgggtgcagtaggagcttatgcc tggagtggtactgtggtccagcagacatctcatggacatttgatctttcctaaacaagcc tttgaccaaattctgcaagataaaaatcacagttcatacttaggttactctgtggctacg atttctactggaaaaggcgttcactttgttgctggtgctcctcgggcaaattatactggc cagatagtgctatacagggttaatgagagtggcaatgtcaccattattcaagctcaccga ggtgaccagattggctcctattttggtagtgtgctgtgctcagttgacgtgaataaagac agtgttacagatgtgctcctggtgggtgcaccgatgtacatgaatgacctaaagaaagag gaaggaagagtctacctatttactatcacaaagggcattttgaattggcaccaatttctt gaaggccctgatggtgttgaaaattctcggtttggttcagcgattgcagctctttcagat atcaacatggatggttttaatgatgtaatagttggttcacccttggaaaatcagaactct ggagctgtgtacatctacaatggtcatgagggcaccattcacagggagtattcccagaaa atcttgggatctgatggagcctttaggagccatctccaatactttgggagatctttggat ggctacagtgatttaaatggggattccatcaccgatgtgtccattggagcttttggacaa gtggttcagctctggtcacagagtattgctgatgtatctgtgaatgcttccttcacacca gaaaaaattactttgttcaacaagaatgctgacataaaactcaaactctgtttcagtgca aagtttagacctactaagcaaaacagtcaagtggccattacatacaatatcacaattgat gcagacctgtattcatccagagtaacctctagggggttatttaaagaaaataatgaaaga tgcctgcagaagaatatgacagtaagtcaaacacagagttgctctgagtacatcatccac atacagaaaccctccgatgttgtcagctctttggatctgtgtgtgaacatcagtctggaa aaccctggcaccagccctgcgcttgaagcctactctgagaaggccaaggtcttcagtatc cctttctacaaggactgtggggatgacggagtctgcagctctgatctagttctagatgtc caacagctgtcagctgctcaagatcaaccctttattgtcagcaaccaaaacaaaaggtta acattttcagtaatgctgaagaataaaagggaaagtgcctacaacactggaattgttatt gatttttcagaaaacttgttttttgcttcctggaccatgccggttgatggaacagaagtc atatgccagattgcttcatctcagaagtctgttacctgtgatgtaggctaccctgcttta aagagacagcaacaggtgactttcatgattaactttgacttcaatcttcaaaaccttcag aatcaggcgtctctcaatttccaagccttaagcgaaagctctgaagaaaacaaggcagat aatttggtcaatttcaaaatccctctgctgtatgacgctgatattcatataacaagatct accaatataaatttctatgaagtctcctcagatgggaatattccgtcaatcgtgcacagt tttgaagatattggtccaaaattcatcttctctgttaaggtaacaacagggagtatccca gtcagcatggcatccatgatcatccacatccctcaatacaccaaagaaaagaacccgttg atgtacgtgactggggtgcacacagatcaggctggcgacatcagttgtaatgccgaaata aatccactgaaaataggacacacggcttcttctgtatctttcaacagtgaaaatttccgg cacataaaagaattgaactgcagaagtgcttcatgtagtaatgttacctgctggctgaaa gacctccaggtcaaaagagagtacttccttaatgtgtcaaccagaatttggaacgggact tttgcagcatcaaccttccagacagtacagctgacggcatctgcagaaatcgacacctat aacccccagatatatgtgatcgaagaaaacacagtcacgattcccattacgataatgaaa cctcatgagaaagctgaagtaccaactggagttatagtaggaagtgtaattgctggaatc cttttgctattagctctggttgcggttttatggaagctcggcttcttcaaaagaaaatat gaaaaaatgtccaaaactgcggatgagatcgacgagaccacagaactcaacagctga

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