Crocuta crocuta (spotted hyena): 144224240
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Entry
144224240 CDS
T11532
Symbol
PRKN
Name
(RefSeq) E3 ubiquitin-protein ligase parkin isoform X1
KO
K04556
parkin [EC:
2.3.2.31
]
Organism
ccru Crocuta crocuta (spotted hyena)
Pathway
ccru04120
Ubiquitin mediated proteolysis
ccru04137
Mitophagy - animal
ccru04141
Protein processing in endoplasmic reticulum
ccru05012
Parkinson disease
ccru05014
Amyotrophic lateral sclerosis
ccru05022
Pathways of neurodegeneration - multiple diseases
Brite
KEGG Orthology (KO) [BR:
ccru00001
]
09120 Genetic Information Processing
09123 Folding, sorting and degradation
04141 Protein processing in endoplasmic reticulum
144224240 (PRKN)
04120 Ubiquitin mediated proteolysis
144224240 (PRKN)
09140 Cellular Processes
09141 Transport and catabolism
04137 Mitophagy - animal
144224240 (PRKN)
09160 Human Diseases
09164 Neurodegenerative disease
05012 Parkinson disease
144224240 (PRKN)
05014 Amyotrophic lateral sclerosis
144224240 (PRKN)
05022 Pathways of neurodegeneration - multiple diseases
144224240 (PRKN)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:
ccru04131
]
144224240 (PRKN)
04121 Ubiquitin system [BR:
ccru04121
]
144224240 (PRKN)
03029 Mitochondrial biogenesis [BR:
ccru03029
]
144224240 (PRKN)
Enzymes [BR:
ccru01000
]
2. Transferases
2.3 Acyltransferases
2.3.2 Aminoacyltransferases
2.3.2.31 RBR-type E3 ubiquitin transferase
144224240 (PRKN)
Membrane trafficking [BR:
ccru04131
]
Autophagy
Mitophagy
PINK1-Parkin associated proteins
144224240 (PRKN)
Aggrephagy
Other aggrephagy associated proteins
144224240 (PRKN)
Xenophagy
Other xenophagy associated proteins
144224240 (PRKN)
Ubiquitin system [BR:
ccru04121
]
Ubiquitin ligases (E3)
Single Ring-finger type E3
RBR proteins
144224240 (PRKN)
Mitochondrial biogenesis [BR:
ccru03029
]
Mitochondrial quality control factors
Mitophagy factors
Parkin-dependent mechanism factors
144224240 (PRKN)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
zf-RING_14
zf-RING_12
ubiquitin
IBR_2
IBR_1
IBR
Rad60-SLD
Rcat_RNF216
Rad60-SLD_2
Dsc3_N
Crinkler
Motif
Other DBs
NCBI-GeneID:
144224240
NCBI-ProteinID:
XP_077611275
LinkDB
All DBs
Position
Unknown
AA seq
462 aa
AA seq
DB search
MIVLVRFNSSHGFPVEVDSDTSIFQLKEVVAKRQGVPADQLRVIFAGKELRNDLTVQSCD
LDQQSIVHVVLRPCRKGQEREESDGAQNAAEGAGRQPESLTRVDLSRSVLPALSGGLAVI
LNNDREETLPTGRPAGRRPYNSFYVYCKGPCQRIQPGKLRVRCGTCRQTTLTLAQGPSCW
DDVLVPNRMTGECQTASCPGTTAEFFFKCGAHPTSDKETSVALNLITANSRDISCITCTD
IRSPVLVFQCNHRHVICLDCFYLYCVTRLNDRQFIHDPQLGYSLPCVAGCPNSLIKELHH
FRILGEEQYNRYQQYGAEECVLQMGGVLCPRPGCGAGLLPEPGRRRVTCEGGNGLGCGFV
FCQDCKEAYHEGECSALFEASGAVSQAYRVDEKAAERARWEEASKETIKKTTKPCPRCHV
PIEKNGGCMHMTCPQPPCGLEWCWACGCEWNRACMGDHWFDV
NT seq
1389 nt
NT seq
+upstream
nt +downstream
nt
atgatagtgttggtcaggttcaactccagccatggcttccctgtggaggtcgattccgac
accagcatcttccagctcaaggaggtggttgctaagcgacagggggttccagctgaccag
ttgcgtgtgattttcgctgggaaggagctcaggaatgacttgacagtgcagagctgtgac
ctggatcagcagagcatcgttcatgtcgtgctgagaccctgcagaaaaggccaagaaagg
gaagaaagtgatggcgcacagaacgctgcagagggcgcggggagacagcccgagagcttg
acgcgcgtggacctcagccgctcggtcctccctgcgctctcggggggtctggctgtgatc
ctgaacaatgaccgcgaggagaccctaccgactggaaggccagcaggtagaagaccctac
aacagcttttatgtttattgcaaaggcccctgtcaaagaatacagccaggaaaactcagg
gtgcggtgtggtacctgccgacagacaacgctcaccttggcccagggtccatcttgctgg
gacgatgtcttagtcccaaaccggatgactggtgaatgtcaaactgcaagttgtcctggg
actacagccgaatttttctttaaatgtggagcacacccaacctctgacaaggaaacatca
gtagctttgaacctgatcaccgcaaacagccgcgacatcagctgcatcacgtgtaccgac
atcaggagtcctgtcctggttttccagtgcaaccaccgccatgtgatttgcttagactgt
ttctacttatactgtgtgacaagacttaatgacaggcagtttatccatgaccctcagctg
ggctactctctgccgtgtgtggctggctgccccaactccttgattaaagagctccatcac
ttcaggattcttggagaagagcagtacaaccggtaccagcaatatggcgctgaagagtgc
gtgctacagatggggggcgtgctgtgtcctcgcccaggctgtggagcagggctgcttccc
gagcccggcagaaggagggtcacttgtgaagggggaaatggtctgggctgtgggttcgtc
ttttgccaggactgtaaggaagcgtaccatgaaggtgaatgcagcgccctatttgaagcc
tcgggagcagtttctcaggcctacagagttgacgagaaggccgcggagcgggctcggtgg
gaagaggcctctaaagaaacaatcaagaaaaccaccaagccctgtccccgttgccacgtg
ccaattgaaaaaaatggaggatgcatgcacatgacgtgcccgcagcccccgtgcggtctg
gagtggtgctgggcctgcggctgcgagtggaaccgcgcctgcatgggggaccactggttc
gacgtgtag
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integrated database retrieval system
