Crocuta crocuta (spotted hyena): 144226380
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Entry
144226380 CDS
T11532
Symbol
KIT
Name
(RefSeq) mast/stem cell growth factor receptor Kit isoform X1
KO
K05091
proto-oncogene tyrosine-protein kinase Kit [EC:
2.7.10.1
]
Organism
ccru Crocuta crocuta (spotted hyena)
Pathway
ccru04010
MAPK signaling pathway
ccru04014
Ras signaling pathway
ccru04015
Rap1 signaling pathway
ccru04072
Phospholipase D signaling pathway
ccru04151
PI3K-Akt signaling pathway
ccru04640
Hematopoietic cell lineage
ccru04916
Melanogenesis
ccru05200
Pathways in cancer
ccru05221
Acute myeloid leukemia
ccru05224
Breast cancer
ccru05230
Central carbon metabolism in cancer
Brite
KEGG Orthology (KO) [BR:
ccru00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
144226380 (KIT)
04014 Ras signaling pathway
144226380 (KIT)
04015 Rap1 signaling pathway
144226380 (KIT)
04072 Phospholipase D signaling pathway
144226380 (KIT)
04151 PI3K-Akt signaling pathway
144226380 (KIT)
09150 Organismal Systems
09151 Immune system
04640 Hematopoietic cell lineage
144226380 (KIT)
09152 Endocrine system
04916 Melanogenesis
144226380 (KIT)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
144226380 (KIT)
05230 Central carbon metabolism in cancer
144226380 (KIT)
09162 Cancer: specific types
05221 Acute myeloid leukemia
144226380 (KIT)
05224 Breast cancer
144226380 (KIT)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
ccru01001
]
144226380 (KIT)
09183 Protein families: signaling and cellular processes
04090 CD molecules [BR:
ccru04090
]
144226380 (KIT)
Enzymes [BR:
ccru01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.1 receptor protein-tyrosine kinase
144226380 (KIT)
Protein kinases [BR:
ccru01001
]
Receptor tyrosine kinases (RTK)
PDGFR family [OT]
144226380 (KIT)
CD molecules [BR:
ccru04090
]
Proteins
144226380 (KIT)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Pkinase
Ig_3
I-set
ig
Ig_2
Ig_PDGFR_d4
IBV_3B
C1-set
C2-set_2
Motif
Other DBs
NCBI-GeneID:
144226380
NCBI-ProteinID:
XP_077613896
LinkDB
All DBs
Position
Unknown
AA seq
978 aa
AA seq
DB search
MRGARGAWDFLCVLLLLLRVQTGSSQPSVSPGERSPPSIHPATSELIVSVGDEIRLLCTD
PGFVKWTFETLGQSSENTHYEWITEKAEATNTGNYTCTNGGGLSSSIYVFVRDPAKLFLV
DAPLYGKEDHDTLVRCPLTDPEVTNYSLRGCEGKPLPKDLTFTADPKAGITIRNVKREYH
RLCLHCSADQKGKSVLSKKFTLKVRAAIRAVPVVSVSKASYLLREGEEFSVLCLIKDVSS
SVDSMWIKENSPQTNAQPQSNSWHQGDFNFVRQERLTISSARVNDSGVFMCYANNTFGSA
NVTTTLEVVDKGFINIFPMMNTTIFVNDGENVDLIVEYEAYPKPEHQRWVYMNRTLTDKW
EDYPKSDNESNIRYVSELHLTRLKGNEGGTYTFQVSNSDVNSSVTLNVYVNTKPEILTHE
SLPNGMLQCVVAGFPEPTVNWYFCPGPEPRCPVPIGPLDVQLQNSSVSPSGKLVVQSSID
YSAFKHNGTIECRAFNNVGKTSAFFNFAFKGNSKEQIHPHTLFTPLLIGFVIAAGMMCII
VMILTYKYLQKPMYEVQWKVVEEINGNNYVYIDPTQLPYDHKWEFPRNRLSFGKTLGAGA
FGKVVEATAYGLIKSDAAMTVAVKMLKPSAHLTEREALMSELKVLSYLGNHMNIVNLLGA
CTVGGPTLVITEYCCYGDLLNFLRRKRDSFICSKQEDQAEVALYKNLLHSKESSCNDSTN
EYMDMKPGVSYVVPTKPDKRRSARIGSYIERDVTPAIMEDDELALDLEDLLSFSYQVAKG
MAFLASKNCIHRDLAARNILLTHGRITKICDFGLARDIKNDSNYVVKGNARLPVKWMAPE
SIFNCVYTFESDVWSYGIFLWELFSLGSSPYPGMPVDSKFYKMIKEGFRMLSPEHAPAEM
YDIMKTCWDADPLKRPTFKQIVQLIEKQISDSTNHIYSNLANCSPSRERPSAVDHCVRIN
SVGSSASSTQPLLVHEEA
NT seq
2937 nt
NT seq
+upstream
nt +downstream
nt
atgagaggcgctcgcggcgcctgggattttctctgcgtcctgctcctcctgctccgcgtc
cagacaggctcttcccaaccatctgtgagtccaggggaacggtctcccccgtccatccat
ccggcaacatcagagttaatagtcagtgttggcgacgagattaggctgttgtgcaccgat
ccaggatttgtcaaatggacttttgagaccctgggtcaatcgagtgagaacacacactat
gaatggatcacggagaaagctgaggccaccaacacgggcaattacacgtgtaccaatgga
ggcggcttaagcagttccatttatgtgtttgtgagagatcctgcaaagcttttcctcgtg
gacgctcccttgtatgggaaagaagaccatgatacactggtccgctgccctctgacagac
ccagaggtgaccaattactccctccgggggtgtgaggggaagcctctgcccaaggacttg
actttcaccgctgaccccaaggctggcatcacaatcagaaacgtgaagcgtgaatatcat
cgcctctgtctgcactgctctgcggaccagaagggcaagtctgtgctgtcaaagaagttc
accctgaaagtgagggcagccatcagagctgtcccagttgtgtctgtgtcgaaagcaagc
tatcttcttagggaaggggaagaattctccgtgttgtgcttgataaaagatgtgtctagt
tccgtggactcgatgtggataaaggaaaacagcccgcaaacgaacgcacagccacagagt
aatagctggcatcaaggtgacttcaattttgtacgtcaggaaagattgactatcagctca
gcaagagttaacgattctggagtgttcatgtgttatgccaataatacttttggatcagca
aatgtcacaacaaccttggaagtagtagataaaggattcattaatatcttccctatgatg
aatactacaatattcgtgaatgatggagagaatgtggatctgattgttgaatatgaggca
tatcccaagcctgagcaccaacggtgggtctatatgaacagaacactcaccgataaatgg
gaagattatcccaaatctgacaacgaaagtaatatcagatatgtgagtgaacttcatcta
accagattaaaagggaacgaaggaggcacttacacatttcaggtgtccaattccgatgtc
aattcttccgtgacattgaatgtttacgtgaacacaaaaccagaaatcctgactcatgaa
agtctcccgaatggcatgctccagtgtgtggtagccggattcccggagcccacagtaaat
tggtacttttgtccaggacctgagccaagatgccctgttcctatcgggccgctggatgtg
cagctgcaaaactcatctgtatcaccatccggaaaactagtggttcaaagctccatcgat
tatagtgctttcaagcacaacggcacaatcgagtgtagggcttttaacaatgtgggcaag
acctctgccttttttaactttgcatttaaaggtaacagcaaagaacaaatccatccccac
accctgttcacacctttgctgattggttttgtgattgcggctggtatgatgtgcattatc
gtgatgatacttacctacaaatatttacagaaacccatgtatgaagtccagtggaaggtt
gttgaggagataaatggaaacaattacgtttacatagacccaacacaacttccttatgat
cacaaatgggagtttcccagaaacaggctgagttttgggaaaaccttgggtgccggtgcc
tttgggaaagtggttgaggccactgcgtatggcctgattaagtcggatgcggccatgacc
gttgctgttaagatgctcaaaccaagtgcccatttaaccgaacgagaagccctcatgtcc
gagctcaaagtcttgagttacctcggcaatcatatgaatattgtgaatcttcttggagca
tgcaccgttggagggcccaccctggtcatcactgagtattgttgctatggtgatcttttg
aattttttgagaagaaaacgtgattcatttatttgctcaaagcaggaagatcaagcagaa
gtagcactttataagaaccttctgcattcaaaggagtcttcctgcaacgatagtactaat
gaatacatggacatgaaacccggcgtttcttatgttgtgccaaccaagccagacaaaagg
agatctgcgagaataggctcatacatagaaagagatgtgactcccgccatcatggaagac
gatgagttggctcttgacctggaggacttgctgagcttctcgtaccaggtggccaagggc
atggcattcctcgcctcgaagaactgtattcacagagacttggctgctagaaatatcctc
cttactcatggtcgaatcacaaagatttgtgattttggtctagccagagacatcaagaat
gattctaattatgtggtcaaaggaaacgctcggctacctgtgaagtggatggcacctgaa
agcattttcaactgtgtgtacacatttgaaagtgatgtctggtcctatgggatttttctg
tgggagctgttctctttaggaagcagcccctaccctggaatgccggtcgattctaagttc
tacaagatgatcaaggaagggttccgaatgctcagccctgagcatgcacctgctgaaatg
tatgacataatgaagacttgctgggatgctgatcccctgaaaaggccaacattcaagcag
atcgtgcagctcattgagaagcagatttcagatagcaccaatcatatttattccaaccta
gcaaactgcagcccgagccgggagcgcccctcggcggtggaccattgtgtgcggatcaat
tctgtgggcagcagcgcgtcttccactcagcctctgctggtgcacgaggaggcctga
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