Crocuta crocuta (spotted hyena): 144228099
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Entry
144228099 CDS
T11532
Symbol
PDE8B
Name
(RefSeq) high affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8B
KO
K18437
high affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8 [EC:
3.1.4.53
]
Organism
ccru Crocuta crocuta (spotted hyena)
Pathway
ccru00230
Purine metabolism
ccru01100
Metabolic pathways
ccru04927
Cortisol synthesis and secretion
ccru04934
Cushing syndrome
ccru05032
Morphine addiction
Brite
KEGG Orthology (KO) [BR:
ccru00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
144228099 (PDE8B)
09150 Organismal Systems
09152 Endocrine system
04927 Cortisol synthesis and secretion
144228099 (PDE8B)
09160 Human Diseases
09165 Substance dependence
05032 Morphine addiction
144228099 (PDE8B)
09167 Endocrine and metabolic disease
04934 Cushing syndrome
144228099 (PDE8B)
Enzymes [BR:
ccru01000
]
3. Hydrolases
3.1 Acting on ester bonds
3.1.4 Phosphoric-diester hydrolases
3.1.4.53 3',5'-cyclic-AMP phosphodiesterase
144228099 (PDE8B)
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
PDEase_I
PDE8A_N
PAS_9
PAS
PAS_3
PDE8_3rd
PAS_4
PAS_8
JetB
DHH
Motif
Other DBs
NCBI-GeneID:
144228099
NCBI-ProteinID:
XP_077616027
LinkDB
All DBs
Position
Unknown
AA seq
761 aa
AA seq
DB search
MRLTQDPIQVLLIFAKEDSQSDGFWWACDRAGYRCNIARTPESALECFLDKHHEIIVIDH
RQTRNFDAEAVCRSIRATNPSEHTVILAVVSQASGDHEEASVLPLLHAGFNRRFMENSSI
IACYNELIQIEHGEVRSQFKLRACNSVFTALDHCHEAIEITSDDHVIQYVNPAFERMMGY
HKGELLGKELAELPKSDKNRADLLDTINTCIKKGKEWQGVYYARRKSGDSIQQHVKITPV
IGQGGKIRHFVSLKKLCCTTDNNKQIHKIHRDSGDNSQTESHSFRYKNRRKESIDVKSIS
SRGSDAPSLQNRRYPSMARIHSMTIEAPITKVINIINAAQENSPVTVAEALDRVLEILRT
TELYSPQLGTKDEDPHTSDLVGGLMTDGLRRLSGNEYVFTKNVHQSHSHLAMPITINDVP
PCIAQLLDNEESWEFNIFELEAVTHKRPLVYLGLKVFSRFGVCEFLHCSETTLRAWLQVI
EANYHSSNAYHNSTHAADVLHATAFFLGKERVKGSLDQLDEVAALIAATVHDVDHPGRTN
SFLCNAGSELAVLYNDTAVLESHHTALAFQLTVKDSKCNIFKNIDRNHYRTLRQAIIDMV
LATEMTKHFEHVNKFVNSINKPLAAETEGSDCECNPTGKNFPENQILIKRMMIKCADVAN
PCRPLDLCIEWAGRISEEYFAQTDEEKRQGLPVVMPVFDRNTCSIPKSQISFIDYFITDM
FDAWDAFAHLPALMQHLADNYKHWKTLDDLKCKSLRLPSDS
NT seq
2286 nt
NT seq
+upstream
nt +downstream
nt
atgagactgacgcaggatcctattcaggttttgctgatctttgcaaaggaagatagtcag
agtgatggattctggtgggcctgtgaccgagctggttatagatgcaatattgcccggact
ccagagtcagctcttgaatgctttctagataaacatcatgaaattattgtaatagatcac
agacagactcgaaactttgatgcagaagctgtgtgcaggtcgatccgtgccacaaatccc
tccgagcacacggtgatcctggcagtggtttctcaagcatcgggcgaccatgaagaggcc
tcggtcctcccgctcctgcatgcaggcttcaacaggagatttatggagaatagcagcata
attgcttgctataatgaactgattcaaatagaacacggggaagttcgctcgcagttcaaa
ttacgggcctgtaattcagtgtttacagcattagaccactgtcatgaagccatagaaatt
acaagtgatgaccatgtgattcagtatgtcaacccagcttttgaaaggatgatgggctac
cacaaaggcgagctcctggggaaagagcttgccgagctgcccaaaagtgataagaaccgg
gcagaccttcttgacaccatcaacacgtgcatcaagaagggcaaggagtggcagggggtt
tactatgccagaaggaaatccggggacagcatccagcagcacgtgaagatcaccccagtg
attggccaaggagggaaaattaggcattttgtctccctcaagaagctgtgttgtaccact
gacaataataagcagattcacaagattcatcgtgactcaggagacaattctcagacagag
tctcattcattcagatacaagaacaggaggaaagagtccattgatgtgaaatcgatatca
tctcgaggcagtgatgcaccaagcctccagaatcgtcgctatccatccatggcgaggatt
cattccatgaccattgaggctcccatcacaaaggttataaatataatcaatgcagcccaa
gaaaacagccctgtgacagtagcagaagccttggatagagttttggaaattttacggacc
acagaactgtattcccctcagctgggtaccaaagatgaagatcctcacaccagtgatctc
gttggaggcctgatgaccgatggcttgagaaggttgtcaggaaacgagtatgtgttcact
aagaatgtgcaccagagtcacagtcaccttgcgatgccaataaccatcaacgatgtcccc
ccttgtatcgctcaattacttgataatgaggaaagttgggagttcaacatctttgaattg
gaagctgttacacataaaaggccattggtttacctgggcttaaaagtattttcccggttt
ggagtatgtgaatttctacattgttctgaaactactctgcgggcctggctccaagtgatt
gaggccaactaccactcttccaatgcttaccataactccacccatgctgccgatgtcctg
cacgccactgccttcttccttggaaaggaaagagtaaagggaagcctcgatcagctggat
gaggtggcagcactgattgctgccacagtccacgacgtggatcacccgggcaggaccaac
tcattcctgtgcaacgcgggcagtgaacttgctgtgctctataatgacaccgctgtcttg
gagagtcaccacaccgccctggccttccagctcaccgtcaaggacagcaaatgcaacatt
tttaagaacattgacaggaaccactatcgaacactgcgccaggctattattgacatggtt
ttagcaacagagatgacaaaacactttgaacatgtgaacaaatttgtgaacagcatcaat
aagcctctggcggctgagactgagggcagcgactgtgaatgcaaccctactgggaaaaac
tttcctgaaaaccaaatcctgatcaagcgtatgatgatcaagtgtgctgatgtcgccaac
ccatgccgccctctggacctgtgcatcgaatgggccggaaggatctctgaggagtatttt
gcacagactgatgaagagaaaagacaggggctccctgtggtgatgccagtgtttgaccgg
aatacctgcagcatccccaagtcccaaatctctttcattgactacttcataacagacatg
tttgatgcttgggatgccttcgcccatctgccagccctgatgcaacatttggctgataac
tacaaacactggaagacattagatgacctaaagtgcaaaagtctgaggcttccatctgac
agctaa
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