Crocuta crocuta (spotted hyena): 144229205
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Entry
144229205 CDS
T11532
Symbol
PDE10A
Name
(RefSeq) cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A
KO
K18438
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10 [EC:
3.1.4.17
3.1.4.35
]
Organism
ccru Crocuta crocuta (spotted hyena)
Pathway
ccru00230
Purine metabolism
ccru01100
Metabolic pathways
ccru04024
cAMP signaling pathway
ccru05032
Morphine addiction
Brite
KEGG Orthology (KO) [BR:
ccru00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
144229205 (PDE10A)
09130 Environmental Information Processing
09132 Signal transduction
04024 cAMP signaling pathway
144229205 (PDE10A)
09160 Human Diseases
09165 Substance dependence
05032 Morphine addiction
144229205 (PDE10A)
Enzymes [BR:
ccru01000
]
3. Hydrolases
3.1 Acting on ester bonds
3.1.4 Phosphoric-diester hydrolases
3.1.4.17 3',5'-cyclic-nucleotide phosphodiesterase
144229205 (PDE10A)
3.1.4.35 3',5'-cyclic-GMP phosphodiesterase
144229205 (PDE10A)
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
PDEase_I
GAF
GAF_2
GAF_3
SpoVT_C
HD
HD-CE
PEX15_N
Motif
Other DBs
NCBI-GeneID:
144229205
NCBI-ProteinID:
XP_077617333
LinkDB
All DBs
Position
Unknown
AA seq
972 aa
AA seq
DB search
MGVEKTLKERKYRMRIEERKSQHVTGLTDEKVKAYLSLHPQVLDEFVSESVSAETVEKWL
KRKNNKSEDESAPKEVSRYQDTNMQGVVYELNSYIEQRLDTGGDNQLLLYELSSIIKIAT
KADGFALYFLGECNNSLCVFTPPGIKEGKPRLIPAGPIAQGTTISAYVAKSRKTLLVEDI
LGDERFPRGTGLESGTRIQSVLCLPIVTAIGDLIGILELYRHWGKEAFCMSHQEVATANL
AWASVAIHQVQVCRGLAKQTELNDFLLDVSNNPVPKGVSSSPGFMRHTAVFLSDTTAAEG
AVEGAPWLSCGPRDAVTPQSCGPRDAVPPQSCGPRDAVTPPSCGPRDAVPPRPVGPGTLS
PPQSCGPRDAVPAPVLWALGARPLPHSGHRRQLSGRPLCGLQAPSGCKGPARLADTLRLA
NKPPSGTFSGASPAAAFALEPEACECACEPFQESVRVPTECGPIYAKNLVNADRCALFQV
DHKNKELYSDLFDIGEEKEGKPIFKKTKEIRFSIEKGIAGQVARTGEVLNIPDAYADPRF
NREVDLYTGYTTRNILCMPIVSRGSVIGVVQMVNKLSGSAFSKTDENNFKMFAVFCALAL
HCANMYHRIRHSECIYRVTMEKLSYHSICTAEEWQGLMSFNLPVRLCKEIELFHFDIGPF
ENMWPGIFVYMVHRSCGTSCFELEKLCRFIMSVKKNYRRVPYHNWKHAVTVAHCMYAILQ
NNHGLFTDLELKGLLIACLCHDLDHRGFSNSYLQKFDHPLAALYSTSTMEQHHFSQTVSI
LQLEGHNIFSTLSSSEYEQVLEIIRKAIIATDLALYFGNRKQLEEMYQTGSLNLNNQSHR
DRVIGLMMTACDLCSVTKLWPVTKLTANDIYAEFWAEGDEMKKLGIQPIPMMDRDKKDEV
PQGQLGFYNAVAIPCYTTLTQIFPPTEPLLKACRNNLSQWEKVIRGEESAVWISSQPGAH
APSDKPLAKTDD
NT seq
2919 nt
NT seq
+upstream
nt +downstream
nt
atgggggtagagaagactttgaaggaaaggaaatatagaatgagaatagaagagaggaaa
tcccaacatgtaacaggtctgacagatgaaaaagtgaaggcatatctttcccttcacccc
caggtattagatgagtttgtatctgaaagtgttagtgcagagaccgtagaaaaatggctg
aagaggaaaaacaacaaatcagaagatgaatcggctcctaaggaagtcagcaggtaccaa
gatacgaatatgcagggggttgtatatgagttaaacagctacatcgaacagcggctggac
acaggtggggacaatcaactcctcctctatgagttgagtagcatcattaaaatagccaca
aaagctgacggatttgcactgtatttccttggggagtgcaataatagtctgtgtgtgttc
accccacctggaatcaaggaagggaaaccccggctcatccctgctgggcccatcgcccag
ggcaccaccatctctgcctacgtggccaaatccagaaaaacgttgcttgtggaagacatc
cttggggatgaacgatttccaagaggtactggactggagtcagggactcgtatacagtct
gttctttgtttaccgattgtcactgcaattggtgatttgattggtatccttgagctgtat
cggcactggggcaaagaagccttctgtatgagtcaccaggaggtcgcgacagcaaacctc
gcctgggcttcagtagcaatacatcaggtgcaggtatgcagaggccttgccaagcagacc
gaattgaatgacttcctacttgacgtatcaaacaatcctgtgccgaaaggggtctcgtca
tctccaggtttcatgcgacacacggctgtgtttctctctgataccacggcggccgagggg
gcggtagaaggggccccgtggctttcctgtgggccccgggacgcagtcaccccccagtcc
tgtgggccccgggacgctgtccccccccagtcctgtgggccccgggacgcagtcaccccc
ccgtcctgtgggccccgggacgctgtccccccccgtcctgtgggccccgggacgctgtcc
ccaccccagtcctgtgggccccgggacgctgtccccgccccagtcctgtgggccctggga
gcgcggccgctcccccactccggccaccggaggcagctgtcagggaggcccctgtgtggg
ctgcaggcccccagcggctgtaagggtcctgcccgcctggcagacactttaagattagca
aacaaacctccttcaggtacgttttcaggagcttctccagctgctgcctttgcgctggaa
cccgaggcgtgtgagtgtgcgtgtgagccctttcaggaaagtgtccgggtccccaccgag
tgtggccctatatatgcaaaaaacctggtgaatgcagaccgttgcgcacttttccaggtg
gaccataagaacaaggagttatattcagacctttttgatatcggagaggaaaaggaagga
aagcccatcttcaagaagaccaaagagatcagattttcaattgagaaaggaattgcgggt
caggtggcgagaacgggggaggtcctgaacattccagacgcctatgcggacccacgcttc
aacagagaagtggacttgtacacaggatacaccacgcggaacatactatgcatgcccatc
gtgagtcgggggagtgtcatcggtgtggtgcagatggtcaacaagctgagcggcagcgcc
ttctcgaaaacggacgagaacaacttcaagatgtttgcggtcttctgcgcgctagcctta
cactgtgccaatatgtaccacaggatccgacactcggagtgcatttaccgggtgacgatg
gagaagctgtcctaccacagcatctgtaccgccgaggagtggcaaggcctcatgagcttt
aacctcccggtgcgcctctgcaaggagattgaattattccactttgacattggtcctttt
gaaaacatgtggcctggaatttttgtctacatggtccatcggtcctgtgggacatcctgc
tttgagcttgaaaagttgtgtcgcttcattatgtctgtgaagaagaactaccggcgggtt
ccgtatcacaactggaagcacgcagtcaccgtggcgcactgcatgtacgccatactccag
aataaccacgggctcttcaccgacctggagctcaaaggactgctgattgcgtgtctgtgt
cacgacctggaccacaggggcttcagtaacagctacctgcagaaattcgaccaccccctg
gccgccctctactccacgtccaccatggagcagcaccacttctctcagaccgtgtccatc
ctgcagctggaagggcacaatatcttctccaccctcagctccagcgaatacgaacaggtg
cttgagatcatccgcaaagccatcattgccacagaccttgctttatactttggaaacagg
aaacagctggaagagatgtaccagaccggatcgctaaaccttaataatcaatcacataga
gaccgtgtcattggtttgatgatgactgcctgtgatctttgttccgtaacgaaactgtgg
ccagttacaaaattgacggcaaatgatatatatgcagagttctgggctgagggtgacgag
atgaagaagctgggaatccagcccatccccatgatggacagagacaagaaggacgaggtc
ccccagggccagctgggtttctacaacgccgtggccattccctgctacaccaccctcacc
cagatcttcccgcccaccgagcccctcctgaaggcgtgcaggaataacctgagccagtgg
gagaaggtgatccgaggggaggagagtgccgtgtggatctcatcccagccgggggcccat
gcgccgtccgacaagccactggcaaagacagacgactga
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