Crocuta crocuta (spotted hyena): 144230910
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Entry
144230910 CDS
T11532
Symbol
PLA2G4A
Name
(RefSeq) cytosolic phospholipase A2 isoform X1
KO
K16342
cytosolic phospholipase A2 [EC:
3.1.1.4
]
Organism
ccru Crocuta crocuta (spotted hyena)
Pathway
ccru00564
Glycerophospholipid metabolism
ccru00565
Ether lipid metabolism
ccru00590
Arachidonic acid metabolism
ccru00591
Linoleic acid metabolism
ccru00592
alpha-Linolenic acid metabolism
ccru01100
Metabolic pathways
ccru04010
MAPK signaling pathway
ccru04014
Ras signaling pathway
ccru04072
Phospholipase D signaling pathway
ccru04217
Necroptosis
ccru04270
Vascular smooth muscle contraction
ccru04370
VEGF signaling pathway
ccru04611
Platelet activation
ccru04664
Fc epsilon RI signaling pathway
ccru04666
Fc gamma R-mediated phagocytosis
ccru04724
Glutamatergic synapse
ccru04726
Serotonergic synapse
ccru04730
Long-term depression
ccru04750
Inflammatory mediator regulation of TRP channels
ccru04912
GnRH signaling pathway
ccru04913
Ovarian steroidogenesis
ccru04921
Oxytocin signaling pathway
ccru05231
Choline metabolism in cancer
Brite
KEGG Orthology (KO) [BR:
ccru00001
]
09100 Metabolism
09103 Lipid metabolism
00564 Glycerophospholipid metabolism
144230910 (PLA2G4A)
00565 Ether lipid metabolism
144230910 (PLA2G4A)
00590 Arachidonic acid metabolism
144230910 (PLA2G4A)
00591 Linoleic acid metabolism
144230910 (PLA2G4A)
00592 alpha-Linolenic acid metabolism
144230910 (PLA2G4A)
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
144230910 (PLA2G4A)
04014 Ras signaling pathway
144230910 (PLA2G4A)
04370 VEGF signaling pathway
144230910 (PLA2G4A)
04072 Phospholipase D signaling pathway
144230910 (PLA2G4A)
09140 Cellular Processes
09143 Cell growth and death
04217 Necroptosis
144230910 (PLA2G4A)
09150 Organismal Systems
09151 Immune system
04611 Platelet activation
144230910 (PLA2G4A)
04664 Fc epsilon RI signaling pathway
144230910 (PLA2G4A)
04666 Fc gamma R-mediated phagocytosis
144230910 (PLA2G4A)
09152 Endocrine system
04912 GnRH signaling pathway
144230910 (PLA2G4A)
04913 Ovarian steroidogenesis
144230910 (PLA2G4A)
04921 Oxytocin signaling pathway
144230910 (PLA2G4A)
09153 Circulatory system
04270 Vascular smooth muscle contraction
144230910 (PLA2G4A)
09156 Nervous system
04724 Glutamatergic synapse
144230910 (PLA2G4A)
04726 Serotonergic synapse
144230910 (PLA2G4A)
04730 Long-term depression
144230910 (PLA2G4A)
09157 Sensory system
04750 Inflammatory mediator regulation of TRP channels
144230910 (PLA2G4A)
09160 Human Diseases
09161 Cancer: overview
05231 Choline metabolism in cancer
144230910 (PLA2G4A)
Enzymes [BR:
ccru01000
]
3. Hydrolases
3.1 Acting on ester bonds
3.1.1 Carboxylic-ester hydrolases
3.1.1.4 phospholipase A2
144230910 (PLA2G4A)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
PLA2_B
C2
cPLA2_C2
Motif
Other DBs
NCBI-GeneID:
144230910
NCBI-ProteinID:
XP_077619412
LinkDB
All DBs
Position
Unknown
AA seq
749 aa
AA seq
DB search
MSFIDPYQHIIVEHQYSHKFTVVVLCATKVTKGAFGDMLDTPDPYVELFISSTPDSRKRT
RHFNNDINPVWNETFEFILDPNQENVLEVTLMDANYVMDETLGTATFPISSMRVGEKKEV
PFIFNQVTEMFLEMSLEVCSSPDLRFSMALCDQEKTFRQQRKENIKENMKKLLGPEKSGG
LYSIRDVPVVAILGSGGGFRAMVGFSGVMKALYESGILDCATYVAGLSGSTWYMSTLYSH
PDFPEKGPEEINKELMKNVSHNPLLLLTPQKVKRYVESLWKKKSSGQPVTFTDIFGMLIG
ETLIHNRMNTTLSSLKEKVNSAQCPLPLFTCLHVKPDVSELMFADWVEFSPYEIGMAKYG
TFMAPDLFGSKFFMGTVVKKYEENPLHFLMGVWGSAFSILFNRVLGVSGSQNKGSTMEEE
LENITAEHIVSNDSSDSDDESQEPKGTENEDAKREYQNDNQASWVHRMIMALVSDSTLFN
TREGRAGKVHNFMLGLNLNTSYPMSPLKDFTTQESLDEDELDTAVADPDEFEQIYEPLDV
KSKKIHVVDSGLTFNLPYPLILRPQRGVDLIISFDFSARPSDSSPPFKELLLAEKWARMN
KLPFPKIDPNVFDREGLKECYVFKPKNPDVEKDCPTIIHFVLANINFRNYKAPGVPRETK
EEKEIADFDIFDDPESPFSTFNFQYPNQAFKRLHDLMHFNTLNNIEVIKNAIVESIEYRR
QNPSRCSVSLSNVEARRFFNKEFLSKPAA
NT seq
2250 nt
NT seq
+upstream
nt +downstream
nt
atgtcatttatagatccttatcagcacattatagtggagcaccagtattcccacaagttc
acagtagtggtgttatgtgccaccaaagtgacaaagggggccttcggtgacatgcttgat
actccagatccgtatgtggaacttttcatctcctcaacccctgacagcaggaagagaaca
agacacttcaataatgacataaacccagtgtggaatgagacctttgaatttattttggat
cctaatcaggaaaatgttttggaggtcacattaatggatgccaattatgtgatggatgaa
actctaggaacagccacattccccatatcctctatgagagtcggagagaagaaagaggtt
ccttttattttcaaccaagtcactgaaatgtttctggaaatgtctcttgaagtttgttca
tccccagacctccgattcagtatggctctgtgtgatcaggagaagactttcagacaacag
agaaaagaaaacataaaggaaaacatgaagaaactcctgggtccagagaagagtggaggc
ctgtattctatacgtgatgtgcctgtggtggccatactgggttcgggtggagggttccga
gccatggtcggattctccggtgtgatgaaggcactatatgaatcaggaattttagattgt
gctacttatgttgctggtctttctggctccacatggtacatgtcaaccttgtattctcac
cctgattttccagagaaagggccagaggagattaataaagagctaatgaaaaatgttagc
cacaacccacttttacttctcacaccgcagaaagttaaaagatatgttgaatctctatgg
aagaagaaaagctctgggcaacctgtcacctttactgatatctttgggatgttaatagga
gaaacactaattcacaatagaatgaacacgaccttgagtagtttgaaggaaaaagttaat
tctgcacaatgccctttaccccttttcacctgtctccatgtcaaacctgatgtttctgag
ctaatgtttgcagattgggttgaatttagtccatatgagattggcatggcaaaatatggt
acttttatggctcctgacttatttggaagcaaattttttatgggaacagttgtgaagaaa
tatgaagaaaaccccttgcatttcttaatgggtgtctggggcagtgccttttctatattg
ttcaacagagtcttaggagtttctggctcacaaaataaaggttccacaatggaggaggaa
ctagaaaatatcacagctgagcatattgtgagtaatgacagctcagatagcgatgatgaa
tcacaagaacccaaaggcactgaaaatgaagatgctaaaagggaatatcaaaatgataac
caagcaagttgggtccatcgtatgataatggctttggtgagtgattcaactttattcaat
accagagaaggacgtgctgggaaggtacacaacttcatgttgggcttgaatctcaataca
tcctatccaatgtctcctctgaaagactttaccacacaggaatccttggatgaagatgaa
ctggatacagctgtagcagatcctgatgaatttgagcaaatatatgagcctctggatgtc
aaaagtaaaaagattcatgtagtggacagtggtctcacatttaacctgccctatcccttg
atcctgagacctcaaagaggagtcgatctcattatctcctttgacttttctgcacggcca
agtgactctagtcctccattcaaggaacttctacttgcagaaaagtgggccagaatgaac
aagctcccctttccaaagattgatcctaatgtgtttgatcgagaaggactgaaggaatgc
tatgtctttaaacccaagaatcctgatgtcgagaaagattgtccaactatcatccacttt
gttctggccaacatcaacttcaggaattacaaggcaccaggtgtcccaagagaaactaag
gaagagaaagaaatagctgattttgatatttttgatgaccccgaatcaccattttcaacc
ttcaactttcaatatccaaatcaagcattcaaaaggctccatgatctcatgcacttcaat
accctgaacaacattgaggtgatcaagaacgccatagttgaaagcattgaatacagaaga
caaaatccttctcgttgctctgtttctcttagtaatgttgaagcaagacgattcttcaac
aaggagtttctaagcaaacccgcagcatag
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