Crocuta crocuta (spotted hyena): 144232328
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Entry
144232328 CDS
T11532
Symbol
MAPK10
Name
(RefSeq) mitogen-activated protein kinase 10 isoform X1
KO
K04440
mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:
2.7.11.24
]
Organism
ccru Crocuta crocuta (spotted hyena)
Pathway
ccru01522
Endocrine resistance
ccru04010
MAPK signaling pathway
ccru04012
ErbB signaling pathway
ccru04014
Ras signaling pathway
ccru04024
cAMP signaling pathway
ccru04068
FoxO signaling pathway
ccru04071
Sphingolipid signaling pathway
ccru04137
Mitophagy - animal
ccru04140
Autophagy - animal
ccru04141
Protein processing in endoplasmic reticulum
ccru04210
Apoptosis
ccru04215
Apoptosis - multiple species
ccru04217
Necroptosis
ccru04310
Wnt signaling pathway
ccru04380
Osteoclast differentiation
ccru04510
Focal adhesion
ccru04517
IgSF CAM signaling
ccru04519
Cadherin signaling
ccru04530
Tight junction
ccru04620
Toll-like receptor signaling pathway
ccru04621
NOD-like receptor signaling pathway
ccru04622
RIG-I-like receptor signaling pathway
ccru04625
C-type lectin receptor signaling pathway
ccru04657
IL-17 signaling pathway
ccru04658
Th1 and Th2 cell differentiation
ccru04659
Th17 cell differentiation
ccru04660
T cell receptor signaling pathway
ccru04664
Fc epsilon RI signaling pathway
ccru04668
TNF signaling pathway
ccru04722
Neurotrophin signaling pathway
ccru04723
Retrograde endocannabinoid signaling
ccru04728
Dopaminergic synapse
ccru04750
Inflammatory mediator regulation of TRP channels
ccru04910
Insulin signaling pathway
ccru04912
GnRH signaling pathway
ccru04914
Progesterone-mediated oocyte maturation
ccru04917
Prolactin signaling pathway
ccru04920
Adipocytokine signaling pathway
ccru04926
Relaxin signaling pathway
ccru04930
Type II diabetes mellitus
ccru04931
Insulin resistance
ccru04932
Non-alcoholic fatty liver disease
ccru04933
AGE-RAGE signaling pathway in diabetic complications
ccru04935
Growth hormone synthesis, secretion and action
ccru04936
Alcoholic liver disease
ccru05010
Alzheimer disease
ccru05012
Parkinson disease
ccru05016
Huntington disease
ccru05017
Spinocerebellar ataxia
ccru05020
Prion disease
ccru05022
Pathways of neurodegeneration - multiple diseases
ccru05132
Salmonella infection
ccru05133
Pertussis
ccru05135
Yersinia infection
ccru05142
Chagas disease
ccru05145
Toxoplasmosis
ccru05152
Tuberculosis
ccru05161
Hepatitis B
ccru05162
Measles
ccru05166
Human T-cell leukemia virus 1 infection
ccru05167
Kaposi sarcoma-associated herpesvirus infection
ccru05169
Epstein-Barr virus infection
ccru05170
Human immunodeficiency virus 1 infection
ccru05171
Coronavirus disease - COVID-19
ccru05200
Pathways in cancer
ccru05208
Chemical carcinogenesis - reactive oxygen species
ccru05210
Colorectal cancer
ccru05212
Pancreatic cancer
ccru05231
Choline metabolism in cancer
ccru05415
Diabetic cardiomyopathy
ccru05417
Lipid and atherosclerosis
ccru05418
Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:
ccru00001
]
09120 Genetic Information Processing
09123 Folding, sorting and degradation
04141 Protein processing in endoplasmic reticulum
144232328 (MAPK10)
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
144232328 (MAPK10)
04012 ErbB signaling pathway
144232328 (MAPK10)
04014 Ras signaling pathway
144232328 (MAPK10)
04310 Wnt signaling pathway
144232328 (MAPK10)
04668 TNF signaling pathway
144232328 (MAPK10)
04068 FoxO signaling pathway
144232328 (MAPK10)
04071 Sphingolipid signaling pathway
144232328 (MAPK10)
04024 cAMP signaling pathway
144232328 (MAPK10)
09133 Signaling molecules and interaction
04517 IgSF CAM signaling
144232328 (MAPK10)
04519 Cadherin signaling
144232328 (MAPK10)
09140 Cellular Processes
09141 Transport and catabolism
04140 Autophagy - animal
144232328 (MAPK10)
04137 Mitophagy - animal
144232328 (MAPK10)
09143 Cell growth and death
04210 Apoptosis
144232328 (MAPK10)
04215 Apoptosis - multiple species
144232328 (MAPK10)
04217 Necroptosis
144232328 (MAPK10)
09144 Cellular community - eukaryotes
04510 Focal adhesion
144232328 (MAPK10)
04530 Tight junction
144232328 (MAPK10)
09150 Organismal Systems
09151 Immune system
04620 Toll-like receptor signaling pathway
144232328 (MAPK10)
04621 NOD-like receptor signaling pathway
144232328 (MAPK10)
04622 RIG-I-like receptor signaling pathway
144232328 (MAPK10)
04625 C-type lectin receptor signaling pathway
144232328 (MAPK10)
04660 T cell receptor signaling pathway
144232328 (MAPK10)
04658 Th1 and Th2 cell differentiation
144232328 (MAPK10)
04659 Th17 cell differentiation
144232328 (MAPK10)
04657 IL-17 signaling pathway
144232328 (MAPK10)
04664 Fc epsilon RI signaling pathway
144232328 (MAPK10)
09152 Endocrine system
04910 Insulin signaling pathway
144232328 (MAPK10)
04920 Adipocytokine signaling pathway
144232328 (MAPK10)
04912 GnRH signaling pathway
144232328 (MAPK10)
04914 Progesterone-mediated oocyte maturation
144232328 (MAPK10)
04917 Prolactin signaling pathway
144232328 (MAPK10)
04926 Relaxin signaling pathway
144232328 (MAPK10)
04935 Growth hormone synthesis, secretion and action
144232328 (MAPK10)
09156 Nervous system
04728 Dopaminergic synapse
144232328 (MAPK10)
04723 Retrograde endocannabinoid signaling
144232328 (MAPK10)
04722 Neurotrophin signaling pathway
144232328 (MAPK10)
09157 Sensory system
04750 Inflammatory mediator regulation of TRP channels
144232328 (MAPK10)
09158 Development and regeneration
04380 Osteoclast differentiation
144232328 (MAPK10)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
144232328 (MAPK10)
05208 Chemical carcinogenesis - reactive oxygen species
144232328 (MAPK10)
05231 Choline metabolism in cancer
144232328 (MAPK10)
09162 Cancer: specific types
05210 Colorectal cancer
144232328 (MAPK10)
05212 Pancreatic cancer
144232328 (MAPK10)
09172 Infectious disease: viral
05166 Human T-cell leukemia virus 1 infection
144232328 (MAPK10)
05170 Human immunodeficiency virus 1 infection
144232328 (MAPK10)
05161 Hepatitis B
144232328 (MAPK10)
05171 Coronavirus disease - COVID-19
144232328 (MAPK10)
05162 Measles
144232328 (MAPK10)
05167 Kaposi sarcoma-associated herpesvirus infection
144232328 (MAPK10)
05169 Epstein-Barr virus infection
144232328 (MAPK10)
09171 Infectious disease: bacterial
05132 Salmonella infection
144232328 (MAPK10)
05135 Yersinia infection
144232328 (MAPK10)
05133 Pertussis
144232328 (MAPK10)
05152 Tuberculosis
144232328 (MAPK10)
09174 Infectious disease: parasitic
05145 Toxoplasmosis
144232328 (MAPK10)
05142 Chagas disease
144232328 (MAPK10)
09164 Neurodegenerative disease
05010 Alzheimer disease
144232328 (MAPK10)
05012 Parkinson disease
144232328 (MAPK10)
05016 Huntington disease
144232328 (MAPK10)
05017 Spinocerebellar ataxia
144232328 (MAPK10)
05020 Prion disease
144232328 (MAPK10)
05022 Pathways of neurodegeneration - multiple diseases
144232328 (MAPK10)
09166 Cardiovascular disease
05417 Lipid and atherosclerosis
144232328 (MAPK10)
05418 Fluid shear stress and atherosclerosis
144232328 (MAPK10)
05415 Diabetic cardiomyopathy
144232328 (MAPK10)
09167 Endocrine and metabolic disease
04930 Type II diabetes mellitus
144232328 (MAPK10)
04936 Alcoholic liver disease
144232328 (MAPK10)
04932 Non-alcoholic fatty liver disease
144232328 (MAPK10)
04931 Insulin resistance
144232328 (MAPK10)
04933 AGE-RAGE signaling pathway in diabetic complications
144232328 (MAPK10)
09176 Drug resistance: antineoplastic
01522 Endocrine resistance
144232328 (MAPK10)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
ccru01001
]
144232328 (MAPK10)
Enzymes [BR:
ccru01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.24 mitogen-activated protein kinase
144232328 (MAPK10)
Protein kinases [BR:
ccru01001
]
Serine/threonine kinases: CMGC group
MAPK family [OT]
144232328 (MAPK10)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
Pkinase
PK_Tyr_Ser-Thr
ABC1
Kdo
RIO1
Kinase-like
APH
FTA2
Motif
Other DBs
NCBI-GeneID:
144232328
NCBI-ProteinID:
XP_077621280
LinkDB
All DBs
Position
Unknown
AA seq
464 aa
AA seq
DB search
MSLHLLYYCSEPTLDVKIAFCQGFDKQVDVSYIAKHYNMSKSKVDNQFYSVEVGDSTFTV
LKRYQNLKPIGSGAQGIVCAAYDAVLDRNVAIKKLSRPFQNQTHAKRAYRELVLMKCVNH
KNIISLLNVFTPQKTLEEFQDVYLVMELMDANLCQVIQMELDHERMSYLLYQMLCGIKHL
HSAGIIHRDLKPSNIVVKSDCTLKILDFGLARTAGTSFMMTPYVVTRYYRAPEVILGMGY
KENVDMWSVGCIMGEMIKGAVLFPGTDHIDQWNKVIEQLGTPCPEFMKKLQPTVRNYVEN
RPKYAGLTFPKLFPDSLFPADSEHNKLKASQARDLLSKMLVIDPAKRISVDDALQHPYIN
VWYDPAEVEAPPPQIYDKQLDEREHTIEEWKELIYKEVMNSEEKTKNGVVKGQPSPSGAA
VNSSESLPPSSSVNDISSMSTDQTLASDTDSSLEASAGPLGCCR
NT seq
1395 nt
NT seq
+upstream
nt +downstream
nt
atgagcctccatttattgtactactgcagtgaaccaaccttggatgtgaaaattgccttt
tgtcagggattcgataaacaagtggatgtgtcatatattgccaaacattacaacatgagc
aaaagcaaagttgacaaccaattctacagtgtggaagtgggagactcaaccttcacagtt
ctcaagcgctaccagaatttaaagcctattggctctggggctcagggaatagtttgtgct
gcgtatgatgccgttcttgacagaaatgtggccattaagaagctcagcagaccctttcag
aaccaaacgcatgccaagagagcttaccgggagctagtcctcatgaagtgtgtgaaccat
aaaaacattattagtttattaaatgtcttcacaccccagaaaacactggaggagttccag
gatgtttacttagtaatggaactgatggatgccaacttgtgtcaggtgattcagatggaa
ttagaccatgagcgaatgtcttacctgctataccaaatgttgtgtggcatcaagcacctt
cactctgctggaattattcacagggatttaaaaccaagtaacattgtagtcaagtctgat
tgtacgttgaaaatcctcgactttggactggccaggacggcaggcacaagcttcatgatg
actccttatgtggttacacgttattacagagcccccgaggttattctgggaatgggctac
aaggagaacgttgacatgtggtcagtagggtgcatcatgggagaaatgataaaaggtgca
gtgctctttcctggcactgatcatattgaccaatggaacaaggtaattgagcaactagga
acaccatgtccagaattcatgaagaaattgcaacccacagtaagaaactatgtggagaat
cggccgaagtatgcaggactcacctttcccaagctctttccagattccctattcccagcg
gactccgagcacaataaactcaaagccagccaagccagggacttattgtcaaagatgcta
gtgattgacccagcaaaaaggatatctgtggatgacgccttacaacacccttacatcaat
gtctggtacgaccctgccgaagtggaggcgcctccacctcagatatatgacaaacagttg
gatgaaagagaacacaccattgaagaatggaaagaacttatctacaaggaagtaatgaat
tcagaagaaaagactaaaaatggtgttgtaaaaggacaaccttctccttcaggtgcagca
gtgaacagcagtgagagtctccctccatcttcgtctgtcaatgacatctcctccatgtcc
accgaccagaccctggcatctgacactgacagcagcctggaagcctcagcaggacccctg
ggttgttgcaggtga
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