Crocuta crocuta (spotted hyena): 144234050 Help Entry 144234050         CDS       T11532                                  Symbol SYNE2 Name (RefSeq) nesprin-2 isoform X1   KO K19346   nesprin-2 Organism ccru  Crocuta crocuta (spotted hyena) Pathway ccru04820   Cytoskeleton in muscle cells Brite KEGG Orthology (KO) [BR:ccru00001]  09140 Cellular Processes   09142 Cell motility    04820 Cytoskeleton in muscle cells     144234050 (SYNE2)  09180 Brite Hierarchies   09182 Protein families: genetic information processing    03036 Chromosome and associated proteins [BR:ccru03036]     144234050 (SYNE2) Chromosome and associated proteins [BR:ccru03036]  Eukaryotic type   Centrosome formation proteins    LINC complex     144234050 (SYNE2) BRITE hierarchy SSDB OrthologParalogGFIT Other DBs NCBI-GeneID:  144234050 NCBI-ProteinID:  XP_077623324 LinkDB All DBs Position Unknown AA seq 6913 aa AA seqDB search MASGPVLPTEDEQASLGIDGRHITLQAEQEDTQKKTFTCWINSQLAKHTPPSVVSDLFAD IKKGHVLLDLLEVLSGQQLPRDKGSNTFQCRINIEHALTFLKNRSIKLINIHVTDIIDGN PSIILGLIWTIILHFHIEELARTLSCNYHQPSLDSVSVADSSPTSSPPAKKCSKAQERWQ MSAKKALLLWAQEQCALCESVNVTDFKSSWRNGMAFLAVIHALRPDLIDMKTVKHRSNKD NLREAFGIAEREFKIPKLLEPEDVDVVDPDEKSIMTYVAQFLQYSKDASGTGDEAQGRMK DAVVWLTLQEKKLQEVLKESENETYSKKYDSLLSFLESFNEGKKPFLDILPVERTLDELN ENQLQLREAWDGLNCQINMWKRDLNHALPSPLHHIEAWLQEVEGLIEEDLPASQDYCEAV ALIQEKMTLIKNLMDKFDCHSNTLLAFENRDEKNLPLVPPKKLEEMKARINNISGEKFIP LLEFHYYKYSVLGLLDEVKTKLDVWDVKYGSKESVELLLEDWHKFIEEEEFLAQLETSLQ KCEEIHKTLDGEYQDISKQYMALEYNICTYRKNIYNVKSTLQKVLTCWATYLEKLRLLKA CFEETKKEQIKEIPFETISQWNVEHTTLNEVGNFLIQVSNDEVGSSISKELRRLNKRWRK FITKTQLEMKLPFIKKQDQPIFDNYENTLLYQEEKPTVDFSTDMSIELPEDHNQDVKAGE GHEKENEFTGQLKVAEDVEKLIEHVETWEAETASLLEPLRCHEGVEASVEESLQHLVAKG SMYEELVSRIEDTLQLDVQNISSQESLQHVLTAGLQAKIQEAKEKVQITMVKLVAMLKNS ADASPDLDVRLKVEESRRELESYMTRAEQLLGQGESRSGLISKYKEALIILNSKSLVKYL KAVEELKNDVTDDVKLSLEEETRGVCAKWESLHHEMSLYSQQLKIDIEKGKLSDSISKLE KQINKEKKLIRRGRTKGLIREHEACFSEEGGLYQLDHHMDVLRELCEELTSQKSQQEVRR ALKDYEQKIERLRKCASEIHTTLQPMVGGLSKNKEPMSTSENGGRSAHGAVASANSDHQP SAEQALGSIEKFSLESKLKPQQEEGVTEKYEKDHNASISSLQESYDIHRENLELCLQNNK FRIISDFSSDEVRSSACLQAKLTDLQVLENDTDACWKEFENTSLKLEELESDIKKPFIRE ARERLKEKEREFQMTLNTRMESLETALKIVLPVEKESLLLCGSDLLLHEMAIQEFHLIDA DGIYQNLRNIQDSIIKQIEVCNNLDQWGDFALKELHPVDLHATQNIILKHRTQLEETNHE VQNCKDALKALEDFLASLRTARLSSELVTDRSAPDTPVASENTLTVENKEEETNLMKDKA RHLDKRLKMLGISFKDAERGDDTCEKLLDALPETLFETRGYGVPEEFPENRLLETCIFKN NELLKNIQDVYNQISKISLKDPTAPAVKQRKKSLMRLDKDLDEYEEEKKCLQEMVNSLPQ FRDGREKSLNQQCQNTALLWENTKASVTECLDQCERVLELLKQYQNFKNVLTTLIQKEEN VISLQASYMGKENLKKRIGEIEVVKEEFNEHLEVVDKINQICRNLQFHLNKMRIFEEPPF EKEANIIVDRWLDINEKTEDYYENLGRALALWDKLFNLKNVIDEWTEKVLRKMELYQLTE EEREKLKEELQVHEQKSLEFSKRVAKIQFLLQSSEIPLELQVMESSVLNKIENVKMSLTG ESNCFALSGHTAELREDLDQAKTQIGMTESLLKALSPTDSLEIFTKLEEIQQQILQQKHS MMLLENQIGCLTPELSELKKQYESVSDLFNTKKSLLQDHFSKLLNDQCKNFNDWFGNIKM NLKECFESSETKKSVEQKLQNLSDFLTLEGRGSKIQQVGTVLNHVKKHLPKAHVKELNSW IINQEIELEKMESICQARAKELNDYLQQLLSLQDDHRNLIMWLTSQEEKWKEMEKSGEKT ELFCEAVARRREQFESMAQLNNSLKEYGLTEEEEIIMESTHLIDRYQTFLRQLCETDEED KLPSTEDQSFNDLAHDIIHWIAGIKESLMVLNSSEGKMPLEERIQKIKEIILLKPEGDAK IQTIMSQAECSKAPLASKTLTDIKNQWDNTLHLANTYLSHQEKLLLEGEKYLQSKEDLRL MLTELKKKQEVGFALQHGLQEKKAQLKIYKKFLQKAQDLTSLLKELKSQGSYLLECTKNP SFSEEPWLEIKLLHESLLQQLQDSVQKLEGHVQEHHSYQDCVTDLNTTLDNISKEFANFL DKPVDQIAVEEKLQKLQELEKRLHLQDDTLEKTLALAKSIKKNTSSVGQKIIKDDIKSLK CKRKDLENRLESAKQETESCLNSILQSKRSMEQKEKFSPPGREKEVTCDVQGSTRDSAAL EKFEQDWEINKNSAVEMVLSKQLSLDVQESMKNTGDEHKVNELQNQPLELDVVLRNEQLK EIEELYARLDAKKAAIEPLEQTEYLNKAETRALVLHNTGYSVNYLDNLLQALITLKKNKE SQYCFLKDFQEQLATVESSVKTLLTEKESLKVGPLGSAAYLDKIKNYLASIEKEKVFLSK MKIEWESLSNCVTDMDKKLLESQIRQLAHSWEQLQQLAQKKYSQQVAKSDEFILLMRQIQ DLEISLQQQQWHLQLGLNSPGEQEGSPGTVALAIELRTVKHRFSVLKGQAEFQMKRIWGE KEKNTLEDAMNNLQKQLKALEPLNTEVEHQIRTCETKTRMKEIILWVKNLLAELTPTIPL LPDDILSQIRKCKVTHDDILDKHQIVELLVEEAKDIIPSLPADESTDLSHLLQDLQNQYQ MLVLKSTERSQQLEFKLEERSQFFAAMEKVQLSLQANEALIIPKMKTASTETELEHERVA LMSSLKELQEAESVTSTHLQEQTDICKDLNVFERLFLDDQLKNLKTRVHRAQRFIQNKCN EVEQKIHFCREFHEKTSMLQKEVDHIQHDKLLLNQEINQDVKEELYNLKDRVTGIQSSIL QALKLKEVFDYIGLSWDCSQLDQLHTQVAKKEKELEEKIKQLDTLVADHSRYQTSLSKLR AMDLQIKKRAEAVLEMHQTSPENSLLDAQILNRRIEKAMSLCQEIIKKLNESKAFDDTFK EKEMLRIKLYAEENDKLHKVLRNNILKAQPKEMDEKNVQDKLENALHVLKQIKTQLEQPL VINLDIEHIQNEKDNCEAFQEQVQAEMDSVRSMTIIEKQRGDNSSGANDVEAKLCDIEDL HIQLTTSIDLRTDVLNDAYESLTRYNEAVTRAMGNFTAREAIVAAHRVDLADPEESLEMS HWQEEELQTAIADIRDLTEKLGTIASPEAKQQLQYTIHELALKDSAVREAAKVRETEIER CLENYKCYRKIKENICTHLSQMETVLGQSIFPLPVSYKEALERLEQSKALESNLVSTKEE FMKLRQVLRHLRHTCTDGDDACLLRTTLALWDKWLSLLEAAKEWEIWCEELKQEWKFVNE EIERETIILDNLQEDLPEVSKTKEVATTEELCELLDCLCRYQDNVEKQQLLLTLLLQRLR SIQIAPQSLEPVETGAAFQEITSMQERCNKLFQKARENKELVENETQERHSLTKEIITLK NLFQQTATSFQNMELQDHPEKAEQFEELQSIFKKGKLTFENIMEKLRIKYSEMYTLVPAE IESQVEECRKALEDIDEKISNEVLKSSPLYTMSRKIDEINNGLHNVEKMLQQKSKNIEKA QGIQKKMWDELDLWHSKLNELDSEVQDLVEQDPGQAQEWMDNLMIPFQQYQQVSQRAESR TSQLNKATVKMEEYHDLLKSTEAWIENTSRLLANPADYASSKMLSQHASTLQMALEDSEQ KHSLLHSIFTDLEDWSIIFETDDLAQSVQKLSGQVAALQQTIMVSLPQIQRMADDVVAIE TEVKSMEKKVSKIKAILLSKEIFDFSPEEHLKHGEVILENIRPMKKTIAEIVSYQVALRL PQTGGKPLPVFPRTDHLLQDIKLLENVTQEQNELLKIVIKQTNECNEEIENLKQILNNYS AEFSHEHVSPDQTANRPQVQGEMEGMEEQILSLNQRKEDLLVDLKAAILNLHQHLQRDQQ ELEQEMPSTGASEEEGVAEREGSEWKLNKTSSMSFLPALKEEVEESSLKSENGDKRAEPT SRSWSSLWKHDKDMEEDRASPSSGTIIQEAAEKISTCENSMAQILAPDSINAEQGPEFSL SPNQREEGATPPPKAVALGFSDEQGAFEATVEKPRPEPAEILHACKTRVAELERWLHQAN VAFEPETLNADMQQLVEQQLVGCQAMLTEIEHKVASLLESCKDQGPGDSGATQQEAEALS LKLKTVKCNLEKVQIMLQEKYSEDQHAATLKKPSEHQNDLQPDNLSEFEPIVTERPQFSR QKDFQQQQVLELKPTEQKDFIKFIEFNAEKIWPQFCQPDKDTTQKSESIKASSSENDAPE SVLSTQGRSGDKWQYLHHELSSKIRLPLPSLVQPQVATNMSILPSVSVYNFRYPTTEELK AYTTQLEDLRQEANNLWIQENLTEETYINLDKKLFELFLALTQCLGSVEEMLQTPGLFRE DVCAQQVHCETLALELKKLYLAMGDKKDGLLKVMTCPGKSTNLFPECFDRLQVYLEHAQA AAASRSKSLKAGLDYTRSYQNEIKRLYDHLTKNKTSLQQSLNEISGQSIDEQLQKADAYT AELQNSESRVAKLRDEGERLRLPYVLLQEVYKLEDVLDTMWGILRARYTELSSPFITESQ QDALLQGMVELVDIGKEKLAHDHLKQAKSKDALQAQIQSHKLFFQKLVADMLLIQTYSNR MLPSSLQKKETFWAEQIKEVKLLEEKSHQRGIKLQSLLQKWEAFDENYASLEKDLEMLVS TLPSVSLVEETEERLVERISFYQQIKRNIDDKHARLYQTLNEGKELVASVSCPELEGQIA KLEEQWLALNKKIDHELHRLQTLLKHLLSYNRDSDQLTKWLESSQQTLNYWKEQSLNVSQ DLDTIRSNINKFFEFSKELDDKSSLKTAVISTGNQLLHLKEADTATLRASLAQFEQKWTM LVTQLPDIQEKLHQLQMEKMPSRKAITEMISWMNNVEHQTAEEDSEHSLSSASQVKNLLH KYKEFRMELDYKQWIVDFVNQSLLQLSTCDVESKRYERTEFAEHLGEMNRQWHRIHGTLN RKIQHLEQLLESITEHENKIQILNNWMEAQEERLKTLQKPGSVISVHKVLPDCQDIENQL ASKSKALEELRQCYLTSESGTMPLLEDTASRIDALFQKRNHVISQVNELKTSMQSVLQEW KIYDDLYDEVTMMTIRFWYCMEHGKPGLLSLEALGCQVQNLQSLQDEAESSEASWEKLQK VIGKLKDRCPLVAEIIEEKCQDTHARWTQVNQDIAEQLQKAQSLLQLWKAHDSAHTEAAA RLKQQEAKYQQLENINMSGNNLAEILTPALQDVKELQDDVQKTKEAFLQNSALLDRLAQL TESSTHVPFSTQQHSLQRASYLENMLLVKANEFEFVLSQFKDFGERLESLKGLITHEEEH LEKLCHQEKEENPDLFLNRVLALTAQSPDVEHLNEVSLKLPLSDIAIKTLQNMNRQWIRA TATALERCSELQATRLNEKFLYCCDKWVQLLEKVEETLKVTVADGLPALLEQQKTYEMLE AEVSINQTVADSYITQSLQLLDTAEIEKRPEFVSKFTKLKERWQSAAQSVRQRKSHIDGL VGQWRYFTTSVEDLLRFLTNTGHLLSAVKSQDCHSLHQIRRLIRELKSKEIHFERWHTTY ALTVETGETLLNTANLETKEVINKKISQLRDDWKDTKLHVGEMINQLQSTSETWDQCEKK IKELKSRLQVLKAQCRDPLPELHEDLHKEKELIKELEKSLANWTQSLSELHTLKTDLSQH ILAEDVMVLEEQTEHLHRQWEDLCLRVAIRKQEVEDRLNSWIVFNEKNKELCAWLVQMEN KVLQTADLSIEEMIEKLQKDCMEEINLFSENKLQLKQMGEQLMKASNKTRAAEIDDKLSK INDRWQHLFDVIGSRVKKLKETFAFIQQLDKNMSNLRTWLARIESELSKPVVYDVCNDQE IQKRLAEQQDLQRDIEQHSAGVESVFNICDVLLHDSDACANETECDSIQQTTRSLDRRWR NICAMSMERRMKIEETWRLWQKFLDDYSRFEDWLKSAERIAAYPNSSEVLYTNAKEELKR FEAFQRQIHERLTQLELINKQYRRLARENRTDSASKLKQMVHEGNQRWDNLQKRVTAVLR RLRHFTNQREEFEGTRESILVWLTEMDLQLTNVEHFSESDADDKMRQLNGFQQEITLNTN KIDQLIVFGEQLIQKSEPLDAVLIEDELEELHRYCQEVFGRVSRFHRRLTSRAPGLEDEK EASENETDMEDPRELQADSWRKRRESEEPSSPQSLCHLVPPAPGPERSGCETPVSVDSIP LEWDHTGDVGGSSSHEDDEEGPYYSALSDIEIPESPEAYLKMTTKTLKASSGKSISEDHS WHVPDSPSCPKHRYKPMGSDRSVQPIPSDSSTPYKPAYVKLLLSPGTDGGKESARVLNSS SQQEDEGLTALTRQHSGAFDRWELIQAQELHNQLRIKQNLQQLNSKISDITTWLKKTEAE LETLKTADPPSGLHEMELRVKQLKEILKAFDTYKALVVSVNMSSKEFLQTESAESKELQG RVGQLALHWDAARGAAERWRESLRRALVQCQDFHQLSQDLLLWLASAESRRQKARVTDPE ADPQMLLECQEELMQLKTELVEREPQVNTLQEISNSLLIKGHGEDYIEAEEKVHVIEKKL KQLLEQVSQDLMSLQGSQNPDPSLPSMDEVDSGDQPPAAPAPAPQAKLGAERMTKDQNKA DSRVPGPGSSRPRRSFLSRVIRAALPLQLLLLLLLLLACLLPASEDDYSCTQANNFARSF YPMLRYTNGPPPT NT seq 20742 nt NT seq  +upstreamnt  +downstreamnt atggcgtctggtcctgtgctacccactgaggatgaacaggcttccttgggcattgatggt cgccatattacactgcaagctgagcaggaagacactcagaagaaaactttcacctgctgg ataaactcacagttggcaaagcacactcctccgtcggttgtatcagacctatttgcggac attaaaaaggggcatgtcctcctggacctgcttgaagtactgtcaggacaacagttgcct cgagacaaaggatctaatacatttcagtgtagaatcaatatagaacatgccctgacattc ctaaaaaaccgttcaatcaagctaataaatattcatgtgactgatattatagatggaaac ccatccattattcttggtctaatttggacaattatactgcactttcacatcgaagagctt gcccggactctttcttgcaattaccatcagccttccctggacagtgtgagtgtggctgac tcatctcctacctcaagtcctccagctaagaaatgctccaaagcccaagaaagatggcag atgtctgcaaagaaggctcttctcttgtgggctcaggagcagtgtgccctgtgtgaatct gtcaatgtgacagattttaagtcaagctggagaaatgggatggcttttctggctgtcatt catgccttgcgaccagacctgattgacatgaaaacagtgaagcacagatccaacaaagac aatctgagagaggcctttggaattgctgaacgggaatttaaaattcccaaattgctagaa ccagaagatgtggatgttgtcgatcctgatgaaaagtcgatcatgacctatgtggcacag tttctacagtattcgaaggatgcatctgggactggagatgaagctcagggcaggatgaaa gacgctgtggtctggttaactctacaagagaaaaaactacaggaagtgctaaaggagtca gagaatgagacctactctaaaaagtatgatagcctgctgtcctttttggagtccttcaat gaaggaaaaaagccctttttggacatcctgccagtggaaaggaccttggatgagctgaat gaaaatcagttgcagctgagagaagcctgggatggcctcaactgccagattaacatgtgg aaaagagacctgaatcatgccttgccctcaccgctgcatcacattgaagcctggctccag gaggtagagggacttatagaggaagacttgccagcttcccaggattactgtgaagccgtg gctctaatacaagaaaaaatgactttaatcaagaatctgatggataaatttgattgtcat tcgaatactctcctggcatttgaaaatagagatgaaaaaaatttgccactggtaccacct aagaaattggaggaaatgaaagcacgaatcaacaacatttcaggggaaaaattcattcca cttctagaatttcattactataagtactcagttcttggtttgctagatgaagtgaagaca aaattggatgtttgggacgtcaaatatgggagcaaagaatctgtggaattgttgctggaa gactggcataaatttattgaagaagaagagttcctagctcaacttgaaacttccttgcaa aaatgtgaagaaatacataagactttagatggagaatatcaggatattagtaaacagtat atggcactggaatataatatttgtacgtatagaaaaaatatatataatgtcaagtccact cttcagaaagttttgacatgttgggctacttatctggaaaaacttcgcttactaaaggct tgttttgaggagacaaagaaggaacagattaaagagattccctttgagacaatatcccag tggaatgtagaacatacaactttaaatgaagtgggaaatttcttaattcaagtcagtaat gatgaagttggatcatctatttctaaagaactgagaaggctgaataaaagatggaggaaa tttattacaaaaactcaacttgaaatgaagctgccctttataaaaaaacaggatcagccc atttttgacaattatgaaaatactctgctatatcaagaagaaaaaccaactgttgatttt tcaacagatatgtcaatagaacttcctgaagatcataatcaggatgtaaaggctggggaa ggacatgaaaaagaaaatgaattcacagggcaactcaaagtggctgaagatgttgaaaaa ctcatcgaacacgtggaaacctgggaggcagaaactgcatctcttttggagcctctgaga tgtcatgagggtgtagaggcctcagtggaagaatctttgcagcatcttgttgccaaaggc tctatgtatgaagagcttgtgtctagaatcgaagacaccttacaactggatgtgcaaaac atttccagccaggagtcccttcaacatgttctcacagctgggcttcaggcaaagattcaa gaagctaaagagaaagttcagatcactatggtaaaattagttgccatgttgaaaaattca gctgatgcttcaccagatctggatgtcaggctgaaagtagaggagtcacggagggaactt gagtcatacatgacgagggctgagcaattacttggacaaggagagagccggagtggacta atttcaaaatacaaggaagcactaataattcttaattctaaaagtctggtcaagtatttg aaagctgttgaggaactgaaaaatgatgtaactgacgatgtaaagctgtctttggaagaa gagactagaggtgtctgtgccaagtgggagtctcttcaccatgagatgtctttgtacagt caacaattgaaaatagacattgaaaaaggaaaactcagtgacagtatttcaaaacttgaa aaacaaataaataaagaaaagaaactaattcgcagaggaaggaccaagggtctcatcagg gaacatgaggcctgcttttctgaggaaggcggtctgtaccagctagatcaccacatggat gtcctgcgggagctgtgtgaagagctgacttcacagaagagtcaacaagaagtgaggaga gccctcaaagattatgaacaaaagattgaaagacttcggaaatgtgcctccgagattcat acgacgctgcagcccatggtgggaggtctgtcgaaaaacaaggagcccatgagcacatct gagaatggagggagaagtgcccacggtgcggtggcgtctgcaaactcagatcatcagcca tcagctgaacaggcactgggatcaattgagaagtttagcctggaatccaagttaaagcct caacaggaagaaggtgttacggagaagtatgagaaggatcacaatgcatctattagtagt ttacaagagagctatgatatccatagagaaaatcttgagctgtgcctgcaaaacaacaaa ttcagaattatttctgatttctccagtgacgaagtaaggagtagtgcttgtctccaggct aagctgacagatctacaggtcttagaaaatgacaccgatgcttgctggaaagagtttgaa aacacttcattgaagttagaagagcttgagagtgacataaagaagccttttataagagag gcaagagagagattaaaagaaaaagaaagagagtttcagatgactctaaataccagaatg gagtctttggagactgcgctgaagattgtgttacctgtggagaaggaatcacttcttctc tgtggctcagacctgctcctccatgaaatggccattcaagaatttcatctcattgatgct gacggcatttatcaaaacctgaggaatatccaagattccatcataaaacagattgaagta tgtaataatttggaccagtggggtgactttgcattaaaggaattacacccagttgatctc catgcaacacagaatatcatactgaaacacagaacacaacttgaagaaacgaaccacgag gtgcagaattgtaaagatgccctcaaagccctggaggactttctagcttctctgagaaca gctagactctcttctgagcttgttacagaccgttcagccccagatacaccggtggcatca gaaaacactttgacagtagaaaataaagaagaagaaaccaatctgatgaaggacaaggcc agacatttggataaacgtctgaagatgcttggtataagctttaaagatgctgaacggggt gacgacacctgtgaaaaacttcttgatgctttgcccgaaacgttatttgagacgcgtggc tatggtgtgccggaggagttccctgaaaacagattactagagacttgtattttcaaaaat aatgaactcctgaaaaatattcaagatgtgtacaatcagatcagtaaaatcagtcttaag gatcccactgctccagctgtgaaacaacggaaaaaatcactaatgagactggataaggat ctagatgaatatgaagaagagaagaaatgcttgcaagaaatggtcaattctcttccgcag ttcagagacggcagagaaaaatcgctgaatcagcagtgccaaaatacggcccttttgtgg gagaataccaaagcttcggtcactgagtgccttgaccaatgtgaaagagttttggagctc ttaaaacagtatcagaattttaaaaatgtcttgacaactttgattcaaaaagaagagaat gtcatctctctgcaggcttcctacatgggaaaagaaaacctgaagaaaagaataggagag attgaagttgtcaaagaagaatttaatgaacatttagaagttgtagacaagattaaccag atctgtagaaacctacaatttcatctaaataaaatgagaatttttgaagagcctcctttt gagaaagaagctaatattattgtggatagatggcttgatataaatgaaaaaaccgaagac tactatgaaaatcttggtcgagctctagctttgtgggacaaactttttaacttaaaaaat gtaattgatgagtggactgaaaaggtccttcgaaaaatggaattatatcaactgactgag gaggaaagagaaaagctgaaggaagagttacaagtccacgaacaaaaatctttagagttt tctaaaagagtggctaaaatacagtttctccttcaaagcagtgaaatacctcttgaattg caggtcatggagtcctctgttttaaacaagatagaaaatgtaaaaatgagtttaacagga gaatccaactgctttgcactcagcggccatacagctgagctaagggaagatctcgaccaa gccaagacccagatcggaatgaccgagtccctgttaaaagccctgtctcctactgacagc ctagagatctttactaaactcgaggagatacaacagcaaatcctacagcaaaagcacagt atgatgttactggagaatcaaataggttgtctgactcctgaactctctgaattaaaaaag caatatgaaagcgtcagtgatttatttaataccaaaaaaagccttttgcaagatcatttt tctaagttattgaatgatcagtgcaagaactttaatgattggtttggcaacattaaaatg aaccttaaggagtgtttcgaatcctcagaaacaaaaaagagtgtggaacaaaagctacaa aacctttctgatttcttaactcttgaaggaagaggcagtaaaatacagcaggtgggaact gtactaaatcatgtgaagaaacatctgcccaaagcacatgttaaggagcttaacagctgg attataaatcaagaaattgaattagaaaaaatggagtccatttgccaggcacgagcaaag gagcttaatgactacttgcagcagctactgagcctccaggatgaccacagaaatctgatt atgtggttgactagtcaagaagagaaatggaaagaaatggaaaaatcaggagagaaaact gagctattttgtgaagctgtagctagaagaagggaacaatttgaatctatggcccagttg aacaattctttgaaggaatatgggcttactgaagaagaagaaataataatggaatcaaca catttgattgatagataccagacatttttgagacaattgtgtgaaactgacgaagaggat aagttaccttctacagaggaccagagctttaatgatcttgcacatgatatcattcattgg atagcagggattaaagagtcccttatggttttgaattcatctgaaggcaaaatgccactt gaggagagaatccagaaaataaaggaaatcattttgctaaagcctgaaggggacgctaaa atacagaccatcatgagtcaggctgagtgcagcaaggctccattggcttccaagaccctt actgatatcaagaaccagtgggacaacacactccatttagccaacacgtatctaagccat caagaaaaacttctactagaaggggagaagtatttgcaaagtaaggaggatctgagatta atgctcacagaactgaaaaagaaacaagaggtgggctttgctcttcaacatggcttgcag gagaagaaagctcagttaaaaatttataagaaattcctccaaaaagcacaggatttgaca tccttgctcaaagagttaaaatctcaaggaagttacctcttagagtgcactaagaatccc agcttcagtgaagagccttggctggagataaagctactacatgaaagtcttctgcaacaa ctacaggattctgtgcaaaaattggaaggtcatgttcaagaacaccactcataccaggat tgtgtcacagacctgaatactacgttggacaatatctccaaggaatttgccaattttctt gataagcctgtggatcaaatagcagttgaggaaaaactgcagaaactgcaggaactagag aaaagactccatttacaagatgacacattggagaagactttagctttagcaaaatccatc aagaaaaatacatcttcagtgggacagaagattattaaagatgatataaaatcacttaag tgtaaacgaaaggatttggaaaacagacttgaatctgctaagcaggagacagaaagttgt ctcaatagcattctccaatcgaaacgctccatggaacagaaagaaaagtttagtcctcca ggcagagagaaggaggtcacttgtgatgtgcaggggtccactcgggactcagctgcactg gaaaagtttgaacaagattgggaaataaacaagaattcagctgtggaaatggttttgtca aaacaactttctctcgatgttcaagaaagcatgaaaaacactggcgacgagcataaagtc aatgagctgcaaaatcaacctttagaattagatgttgtgttaagaaatgaacaattaaag gagatagaggaattgtatgcccggttggatgcaaagaaagcagccattgagccactggaa caaactgagtatctcaataaagcagaaacacgtgccttggttcttcacaatacagggtat 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gcccagagtctgctccagctctggaaggcccatgacagcgctcacaccgaagccgcagca aggctgaagcagcaggaagccaagtaccaacagcttgaaaacatcaacatgtctggaaac aacttggcagagatcctgaccccagccctgcaggatgtaaaggaactgcaggatgatgta cagaagacaaaagaagcctttctccagaattccgctctcctggatcgacttgcgcagctc acggagtccagtacccatgtgcccttctccacacaacagcactccctccagagggcttcc tacttggaaaacatgttgcttgtgaaagctaatgaatttgagtttgtcctttcacagttc aaggattttggggaacggttggaatctttaaaaggtctcattacgcatgaagaagagcat ttagaaaaactctgccatcaagaaaaagaagaaaatcccgacttattcctgaaccgtgtg ctggcactgacagcccaatcacctgatgttgaacatttgaatgaagtaagcctcaagctc cctcttagtgacatagcaataaagacgttacaaaatatgaaccgacagtggattcgggcc acagccacagcccttgaacgatgcagtgagcttcaggcaactagattgaatgaaaagttt ctttattgctgtgacaaatgggtccagcttctagagaaggtagaagagacgctcaaagtg accgtggctgacggcctcccggctctcctggaacagcagaaaacatatgagatgttagaa gctgaagtttctataaaccagacagtggctgattcctatattacccagtccttacagctc ttggacacagcagaaatagagaagagaccggaatttgtctcaaagttcacaaaactgaag gagcggtggcagagtgctgcccagagtgtccggcagaggaagagccacatcgatgggctg gtgggacaatggcggtacttcaccacctccgtggaggacttgctccgcttcctcaccaac accggccacctgctgtctgcagtgaagagccaggattgccacagcctccaccaaatcaga aggctgatccgtgagctgaagagtaaagaaatccatttcgagagatggcacaccacctat gcactaaccgtggaaactggggagacgttactgaacacggctaacctggaaacaaaagag gtgattaacaagaaaatcagtcaactccgggatgactggaaagacacaaagctccacgta ggagagatgattaaccagctgcagagcactagtgagacctgggaccagtgtgaaaagaaa atcaaggagctgaaaagcaggctgcaagttttaaaggcacaatgtagagatcctctccca gaacttcatgaggacctccataaggaaaaagagctgattaaggaactagagaagtctttg gccaactggacccagagcctttcagaacttcacactttgaagaccgacttaagccagcac attcttgcggaggacgtgatggttttggaagagcaaacggagcatttgcacagacaatgg gaagacctctgcttgcgagtggctatacgcaaacaggaggttgaagacagactcaattca tggattgtgttcaatgaaaaaaataaagagttgtgtgcgtggctggtgcagatggaaaac aaagttctacagacagcagatcttagtattgaagaaatgattgaaaagttacagaaggac tgcatggaagaaataaacttgtttagtgaaaacaagttacagctgaagcaaatgggtgag cagctgatgaaagccagcaacaagaccagagcagctgagatcgatgacaagctcagcaaa atcaatgaccgctggcagcacctttttgatgtcattggatcaagggtgaagaagctgaag 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