Crocuta crocuta (spotted hyena): 144234884
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Entry
144234884 CDS
T11532
Symbol
HSPA5
Name
(RefSeq) endoplasmic reticulum chaperone BiP
KO
K09490
endoplasmic reticulum chaperone BiP [EC:
5.6.1.10
]
Organism
ccru Crocuta crocuta (spotted hyena)
Pathway
ccru03060
Protein export
ccru04141
Protein processing in endoplasmic reticulum
ccru04612
Antigen processing and presentation
ccru04918
Thyroid hormone synthesis
ccru05012
Parkinson disease
ccru05014
Amyotrophic lateral sclerosis
ccru05020
Prion disease
ccru05022
Pathways of neurodegeneration - multiple diseases
ccru05417
Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:
ccru00001
]
09120 Genetic Information Processing
09123 Folding, sorting and degradation
03060 Protein export
144234884 (HSPA5)
04141 Protein processing in endoplasmic reticulum
144234884 (HSPA5)
09150 Organismal Systems
09151 Immune system
04612 Antigen processing and presentation
144234884 (HSPA5)
09152 Endocrine system
04918 Thyroid hormone synthesis
144234884 (HSPA5)
09160 Human Diseases
09164 Neurodegenerative disease
05012 Parkinson disease
144234884 (HSPA5)
05014 Amyotrophic lateral sclerosis
144234884 (HSPA5)
05020 Prion disease
144234884 (HSPA5)
05022 Pathways of neurodegeneration - multiple diseases
144234884 (HSPA5)
09166 Cardiovascular disease
05417 Lipid and atherosclerosis
144234884 (HSPA5)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03110 Chaperones and folding catalysts [BR:
ccru03110
]
144234884 (HSPA5)
04131 Membrane trafficking [BR:
ccru04131
]
144234884 (HSPA5)
09183 Protein families: signaling and cellular processes
04147 Exosome [BR:
ccru04147
]
144234884 (HSPA5)
Enzymes [BR:
ccru01000
]
5. Isomerases
5.6 Isomerases altering macromolecular conformation
5.6.1 Enzymes altering polypeptide conformation or assembly
5.6.1.10 non-chaperonin molecular chaperone ATPase
144234884 (HSPA5)
Chaperones and folding catalysts [BR:
ccru03110
]
Heat shock proteins
HSP70 / DNAK
144234884 (HSPA5)
Membrane trafficking [BR:
ccru04131
]
Endoplasmic reticulum (ER) - Golgi transport
Forward pathways
ER-Golgi intermediate compartment (ERGIC) proteins
144234884 (HSPA5)
Autophagy
ER-phagy
ER stress-related proteins
144234884 (HSPA5)
Exosome [BR:
ccru04147
]
Exosomal proteins
Exosomal proteins of haemopoietic cells (B-cell, T-cell, DC-cell, reticulocyte, and mast cell)
144234884 (HSPA5)
Exosomal proteins of other body fluids (saliva and urine)
144234884 (HSPA5)
Exosomal proteins of colorectal cancer cells
144234884 (HSPA5)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
HSP70
MreB_Mbl
Hydantoinase_A
FtsA
FGGY_C
DDR
ParM_N
Motif
Other DBs
NCBI-GeneID:
144234884
NCBI-ProteinID:
XP_077624350
LinkDB
All DBs
Position
Unknown
AA seq
654 aa
AA seq
DB search
MKLTLVAAVLLLLGAARAEEEDKKEDVGTVVGIDLGTTYSCVGVFKNGRVEIIANDQGNR
ITPSYVAFTPEGERLIGDAAKNQLTSNPENTVFDAKRLIGRTWNDPSVQQDIKFLPFKVV
EKKTKPYIQVDIGGGQTKTFAPEEISAMVLTKMKETAEAYLGKKVTHAVVTVPAYFNDAQ
RQATKDAGTIAGLNVMRIINEPTAAAIAYGLDKREGEKNILVFDLGGGTFDVSLLTIDNG
VFEVVATNGDTHLGGEDFDQRVMEHFIKLYKKKTGKDVRKDNRAVQKLRREVEKAKRALS
SQHQARIEIESFYEGEDFSETLTRAKFEELNMDLFRSTMKPVQKVLEDSDLKKSDIDEIV
LVGGSTRIPKIQQLVKEFFNGKEPSRGINPDEAVAYGAAVQAGVLSGDQDTGDLVLLDVC
PLTLGIETVGGVMTKLIPRNTVVPTKKSQIFSTASDNQPTVTIKVYEGERPLTKDNHLLG
TFDLTGIPPAPRGVPQIEVTFEIDVNGILRVTAEDKGTGNKNKITITNDQNRLTPEEIER
MVNDAEKFAEEDKKLKERIDTRNELESYAYSLKNQIGDKEKLGGKLSSEDKETMEKAVEE
KIEWLESHQDADIEDFKAKKKELEEIVQPIISKLYGSAGPPPTGDEEPADKDEL
NT seq
1965 nt
NT seq
+upstream
nt +downstream
nt
atgaagctgaccctggtggctgcggtgctgctgctgctcggcgcggcacgggccgaggag
gaggacaagaaggaggacgtgggcacggtggtcggcatcgacctggggaccacctactcc
tgcgtcggggtgttcaagaacggccgcgtggagatcatcgccaacgatcagggcaatcgc
atcacgccgtcttatgtggccttcactcctgaaggggagcggctgatcggcgatgcagcc
aagaaccagctcacctccaaccctgagaacactgtcttcgacgccaagcggctcatcggc
cgcacatggaacgacccatctgtgcagcaggacataaagttcttgcctttcaaggtggtt
gaaaagaaaactaaaccatatattcaagttgatattggaggagggcaaacaaagacattt
gctcctgaagaaatttctgccatggttctcactaaaatgaaggaaactgctgaggcttat
ttgggaaagaaggttacccatgcagttgttactgtaccagcctattttaacgatgcccaa
cgccaggcaaccaaagatgctggaactattgctggattgaatgttatgagaatcatcaac
gagcctacagcagctgccattgcttatggcttggataaaagggagggggagaagaacatc
ctggtatttgacctcggtggtggaacttttgatgtgtctcttctcaccatcgataatggt
gtttttgaagtcgtggctactaatggagacactcatttgggtggagaagactttgatcaa
cgtgtcatggaacacttcattaagctctacaaaaagaagactggcaaagatgtcaggaaa
gacaacagagctgtgcagaaactccgacgtgaggtagaaaaggccaaacgggccctgtct
tctcaacatcaagcaagaattgaaattgagtctttctatgaaggagaagacttctctgaa
actctgactcgggccaaatttgaagagctaaacatggacctgttccgttctaccatgaag
cctgtccagaaggtgctggaggattctgacttaaagaagtctgatattgatgaaattgtt
cttgttggtggctctactcgaattccaaagattcaacaactggttaaagagttcttcaat
ggcaaggagccatcccgtggcataaacccagatgaggctgtagcatatggtgctgctgtc
caggctggggtactctctggtgatcaagatacaggtgatctggtactgcttgatgtatgt
ccccttacacttggtattgagactgtgggaggtgtcatgaccaaactgattccaaggaac
accgtggtgcccaccaagaagtctcagatcttttctacagcttctgataatcaaccgact
gttacgatcaaggtctatgaaggtgaacgacccctgaccaaagacaatcacctcctggga
acttttgatctgactggaattcctcctgctcctcgtggggtcccacagattgaagtcacc
tttgaaatagatgtgaatggcattcttcgagtgacagccgaagacaaaggtacaggtaac
aaaaataagatcacaattaccaatgaccaaaatcgcctgacacctgaagaaattgaaagg
atggttaatgatgctgagaagtttgccgaggaagacaagaagctcaaggagcgcattgat
actagaaatgagttggaaagctatgcctactctctaaagaatcagattggagataaagaa
aagctgggaggtaaactctcttctgaagacaaggagaccatggaaaaagccgtagaggaa
aagattgaatggctagaaagtcaccaagatgctgacattgaagatttcaaagctaaaaag
aaggaactagaagaaattgttcagccaattatcagcaaactctatggaagtgcaggccct
cccccaactggtgatgaagaaccagcagataaagatgagttgtag
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