Crocuta crocuta (spotted hyena): 144237705
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Entry
144237705 CDS
T11532
Symbol
RPS6KB2
Name
(RefSeq) ribosomal protein S6 kinase beta-2
KO
K04688
ribosomal protein S6 kinase beta [EC:
2.7.11.1
]
Organism
ccru Crocuta crocuta (spotted hyena)
Pathway
ccru01521
EGFR tyrosine kinase inhibitor resistance
ccru01522
Endocrine resistance
ccru04012
ErbB signaling pathway
ccru04066
HIF-1 signaling pathway
ccru04140
Autophagy - animal
ccru04150
mTOR signaling pathway
ccru04151
PI3K-Akt signaling pathway
ccru04152
AMPK signaling pathway
ccru04211
Longevity regulating pathway
ccru04213
Longevity regulating pathway - multiple species
ccru04350
TGF-beta signaling pathway
ccru04371
Apelin signaling pathway
ccru04666
Fc gamma R-mediated phagosome formation
ccru04714
Thermogenesis
ccru04910
Insulin signaling pathway
ccru04931
Insulin resistance
ccru05163
Human cytomegalovirus infection
ccru05165
Human papillomavirus infection
ccru05170
Human immunodeficiency virus 1 infection
ccru05200
Pathways in cancer
ccru05205
Proteoglycans in cancer
ccru05207
Chemical carcinogenesis - receptor activation
ccru05210
Colorectal cancer
ccru05212
Pancreatic cancer
ccru05221
Acute myeloid leukemia
ccru05224
Breast cancer
ccru05225
Hepatocellular carcinoma
ccru05226
Gastric cancer
ccru05231
Choline metabolism in cancer
ccru05235
PD-L1 expression and PD-1 checkpoint pathway in cancer
Brite
KEGG Orthology (KO) [BR:
ccru00001
]
09130 Environmental Information Processing
09132 Signal transduction
04012 ErbB signaling pathway
144237705 (RPS6KB2)
04350 TGF-beta signaling pathway
144237705 (RPS6KB2)
04371 Apelin signaling pathway
144237705 (RPS6KB2)
04066 HIF-1 signaling pathway
144237705 (RPS6KB2)
04151 PI3K-Akt signaling pathway
144237705 (RPS6KB2)
04152 AMPK signaling pathway
144237705 (RPS6KB2)
04150 mTOR signaling pathway
144237705 (RPS6KB2)
09140 Cellular Processes
09141 Transport and catabolism
04140 Autophagy - animal
144237705 (RPS6KB2)
09150 Organismal Systems
09151 Immune system
04666 Fc gamma R-mediated phagosome formation
144237705 (RPS6KB2)
09152 Endocrine system
04910 Insulin signaling pathway
144237705 (RPS6KB2)
09149 Aging
04211 Longevity regulating pathway
144237705 (RPS6KB2)
04213 Longevity regulating pathway - multiple species
144237705 (RPS6KB2)
09159 Environmental adaptation
04714 Thermogenesis
144237705 (RPS6KB2)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
144237705 (RPS6KB2)
05205 Proteoglycans in cancer
144237705 (RPS6KB2)
05207 Chemical carcinogenesis - receptor activation
144237705 (RPS6KB2)
05231 Choline metabolism in cancer
144237705 (RPS6KB2)
05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
144237705 (RPS6KB2)
09162 Cancer: specific types
05210 Colorectal cancer
144237705 (RPS6KB2)
05212 Pancreatic cancer
144237705 (RPS6KB2)
05225 Hepatocellular carcinoma
144237705 (RPS6KB2)
05226 Gastric cancer
144237705 (RPS6KB2)
05221 Acute myeloid leukemia
144237705 (RPS6KB2)
05224 Breast cancer
144237705 (RPS6KB2)
09172 Infectious disease: viral
05170 Human immunodeficiency virus 1 infection
144237705 (RPS6KB2)
05163 Human cytomegalovirus infection
144237705 (RPS6KB2)
05165 Human papillomavirus infection
144237705 (RPS6KB2)
09167 Endocrine and metabolic disease
04931 Insulin resistance
144237705 (RPS6KB2)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
144237705 (RPS6KB2)
01522 Endocrine resistance
144237705 (RPS6KB2)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
ccru01001
]
144237705 (RPS6KB2)
Enzymes [BR:
ccru01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.1 non-specific serine/threonine protein kinase
144237705 (RPS6KB2)
Protein kinases [BR:
ccru01001
]
Serine/threonine kinases: AGC group
RSK family [OT]
144237705 (RPS6KB2)
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
Pkinase
PK_Tyr_Ser-Thr
Pkinase_C
Kinase-like
Pkinase_fungal
ABC1
Seadorna_VP7
Motif
Other DBs
NCBI-GeneID:
144237705
NCBI-ProteinID:
XP_077627521
LinkDB
All DBs
Position
Unknown
AA seq
488 aa
AA seq
DB search
MAAVFDLDLETEEGSEGEPEFSPSDVCPLGELRAAGLEPVGHCEEVELTETSVNLGPECI
GPHCFELLRVLGKGGYGKVFQVRKVQGTNLGKIYAMKVLRKAKIVRNAKDTAHTRAERNI
LESVKHPFIVELAYAFQTGGKLYLILECLSGGELFTHLEREGIFLEDTACFYLAEITLAL
GHLHSQGIIYRDLKPENIMLNSQGHIKLTDFGLCKESIHEGAVTHTFCGTIEYMAPEILV
RSGHNRAVDWWSLGALMYDMLTGSPPFTAENRKKTMDKIIKGKLTLPPYLTPDARDLVKK
FLKRNPSQRIGGGPGDAADVQRHPFFRHIHWDDLLARRDPLGRPLTPAPCSGCLQQSEED
VSQFDIHFTRQTPVDSPDDTALSESANQAFLGFTYVAPSVLDSIKEGFSFQPKLRSPRRL
NSSPRTPVSPLKFSPFEGFRPSPGPVEPSEPPLPPLLPPPPPSSSAPLPIRPPSGTKKSK
RGRGRPGR
NT seq
1467 nt
NT seq
+upstream
nt +downstream
nt
atggcggccgtgtttgacctggacctggagacagaggaaggcagcgagggtgagccagag
ttcagcccctcggacgtgtgtccccttggcgagttgagggcagctggcctggagcctgtg
ggacactgtgaggaggtggagctgacggagaccagtgtgaacctgggccctgagtgcatc
gggccccactgctttgagctgctgcgtgtgctgggcaaggggggttacggcaaggtgttc
caggtgcgaaaggtgcagggcaccaacttggggaaaatatatgccatgaaagtcctgagg
aaggccaaaattgtgcgcaacgccaaggacacagcacacacgcgagctgaacggaacatt
ctggagtcggtgaagcaccccttcattgtggagctggcctatgccttccagaccggcggc
aaactctacctcatcctcgagtgcctcagtggcggtgagctcttcacgcatctggagcga
gaaggcatcttcctggaagacacagcctgcttctacctggcagagatcacgctggccctg
ggacatctccactcccaaggcatcatctaccgggacctcaagcctgagaacatcatgctc
aacagccagggccacatcaaactgacagacttcggactctgcaaggagtcgatccacgag
ggcgctgtcacccacactttctgtggcaccattgagtacatggcccctgagattctggtg
cgcagtggccacaaccgggcggtggactggtggagcctgggggccctgatgtatgacatg
ctcactggatcgccacccttcaccgcagagaaccggaagaaaaccatggacaagatcatc
aaagggaagctgacgctgcccccctacctcaccccggatgcccgggacctcgtcaaaaag
tttctgaagcggaatcccagccagcggatcgggggtggccccggggacgctgctgatgtg
cagagacaccccttcttccggcacattcactgggacgacctcctggctcgccgggacccg
cttggacgccccctgacccctgctccctgttcggggtgcttgcagcagtcagaggaggac
gtgagccagtttgacatccacttcacacggcagacgccggtggacagtcccgatgacacg
gccctcagcgagagcgccaaccaggccttcctgggcttcacgtacgtggctccctccgtc
ctggacagcatcaaggagggcttctccttccagcccaagctccgctcccccaggcggctg
aacagcagcccccggaccccggtcagccccctgaaattctcgccctttgaggggttccgg
cccagccctggcccagtggagccctcggagccccccctacctcctctcctgccgccgccg
ccgccctcgagctctgcacccctccccatccgacccccctcagggaccaagaagtccaag
aggggccgtgggcgccctgggcgctag
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integrated database retrieval system
