KEGG   Crocuta crocuta (spotted hyena): 144237741
Entry
144237741         CDS       T11532                                 
Symbol
PPP1CA
Name
(RefSeq) serine/threonine-protein phosphatase PP1-alpha catalytic subunit
  KO
K06269  serine/threonine-protein phosphatase PP1 catalytic subunit [EC:3.1.3.16]
Organism
ccru  Crocuta crocuta (spotted hyena)
Pathway
ccru03015  mRNA surveillance pathway
ccru04022  cGMP-PKG signaling pathway
ccru04024  cAMP signaling pathway
ccru04114  Oocyte meiosis
ccru04218  Cellular senescence
ccru04261  Adrenergic signaling in cardiomyocytes
ccru04270  Vascular smooth muscle contraction
ccru04390  Hippo signaling pathway
ccru04510  Focal adhesion
ccru04611  Platelet activation
ccru04720  Long-term potentiation
ccru04728  Dopaminergic synapse
ccru04750  Inflammatory mediator regulation of TRP channels
ccru04810  Regulation of actin cytoskeleton
ccru04910  Insulin signaling pathway
ccru04921  Oxytocin signaling pathway
ccru04931  Insulin resistance
ccru05031  Amphetamine addiction
ccru05034  Alcoholism
ccru05168  Herpes simplex virus 1 infection
ccru05205  Proteoglycans in cancer
ccru05415  Diabetic cardiomyopathy
Brite
KEGG Orthology (KO) [BR:ccru00001]
 09120 Genetic Information Processing
  09122 Translation
   03015 mRNA surveillance pathway
    144237741 (PPP1CA)
 09130 Environmental Information Processing
  09132 Signal transduction
   04390 Hippo signaling pathway
    144237741 (PPP1CA)
   04024 cAMP signaling pathway
    144237741 (PPP1CA)
   04022 cGMP-PKG signaling pathway
    144237741 (PPP1CA)
 09140 Cellular Processes
  09143 Cell growth and death
   04114 Oocyte meiosis
    144237741 (PPP1CA)
   04218 Cellular senescence
    144237741 (PPP1CA)
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    144237741 (PPP1CA)
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    144237741 (PPP1CA)
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    144237741 (PPP1CA)
  09152 Endocrine system
   04910 Insulin signaling pathway
    144237741 (PPP1CA)
   04921 Oxytocin signaling pathway
    144237741 (PPP1CA)
  09153 Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    144237741 (PPP1CA)
   04270 Vascular smooth muscle contraction
    144237741 (PPP1CA)
  09156 Nervous system
   04728 Dopaminergic synapse
    144237741 (PPP1CA)
   04720 Long-term potentiation
    144237741 (PPP1CA)
  09157 Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    144237741 (PPP1CA)
 09160 Human Diseases
  09161 Cancer: overview
   05205 Proteoglycans in cancer
    144237741 (PPP1CA)
  09172 Infectious disease: viral
   05168 Herpes simplex virus 1 infection
    144237741 (PPP1CA)
  09165 Substance dependence
   05031 Amphetamine addiction
    144237741 (PPP1CA)
   05034 Alcoholism
    144237741 (PPP1CA)
  09166 Cardiovascular disease
   05415 Diabetic cardiomyopathy
    144237741 (PPP1CA)
  09167 Endocrine and metabolic disease
   04931 Insulin resistance
    144237741 (PPP1CA)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01009 Protein phosphatases and associated proteins [BR:ccru01009]
    144237741 (PPP1CA)
  09182 Protein families: genetic information processing
   03021 Transcription machinery [BR:ccru03021]
    144237741 (PPP1CA)
   03019 Messenger RNA biogenesis [BR:ccru03019]
    144237741 (PPP1CA)
   03041 Spliceosome [BR:ccru03041]
    144237741 (PPP1CA)
Enzymes [BR:ccru01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.3  Phosphoric-monoester hydrolases
    3.1.3.16  protein-serine/threonine phosphatase
     144237741 (PPP1CA)
Protein phosphatases and associated proteins [BR:ccru01009]
 Protein serine/threonine phosphatases
  Phosphoprotein phosphatases (PPPs)
   Protein phosphatase-1
    Catalytic subunits
     144237741 (PPP1CA)
Transcription machinery [BR:ccru03021]
 Eukaryotic type
  RNA polymerase II system
   Other transcription-related factors
    Transcription termination factor
     144237741 (PPP1CA)
Messenger RNA biogenesis [BR:ccru03019]
 Eukaryotic type
  mRNA processing factors
   3' end processing
    Cleavage and polyadenylation specificity factor (CPSF) complex
     144237741 (PPP1CA)
Spliceosome [BR:ccru03041]
 Other splicing related proteins
  Spliceosome associated proteins (SAPs)
   Other SAPs
    144237741 (PPP1CA)
SSDB
Motif
Pfam: Metallophos STPPase_N
Other DBs
NCBI-GeneID: 144237741
NCBI-ProteinID: XP_077627576
LinkDB
Position
Unknown
AA seq 317 aa
PIPPPVQGSRPGKNVQLTENEIRGLCLKSREIFLSQPILLELEAPLKICGDIHGQYYDLL
RLFEYGGFPPESNYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFLLRGNHECASINRI
YGFYDECKRRYNIKLWKTFTDCFNCLPIAAIVDEKIFCCHGGLSPDLQSMEQIRRIMRPT
DVPDQGLLCDLLWSDPDKDVQGWGENDRGVSFTFGAEVVAKFLHKHDLDLICRAHQVVED
GYEFFAKRQLVTLFSAPNYCGEFDNAGAMMSVDETLMCSFQILKPADKNKGKYGQFSGLN
PGGRPITPPRNSAKAKK
NT seq 954 nt   +upstreamnt  +downstreamnt
cccattccgcccccagtgcagggctcgcggcctgggaagaatgtgcagctaacagaaaac
gagatccgtggtctgtgcctcaaatcgagggagattttcctgagccagcccattcttctg
gagctggaggcacccctcaagatctgcggtgacatccatggccagtactacgaccttctg
cggctgtttgagtacggcggcttccctccggagagcaactacctcttcctgggggactac
gtggaccggggcaagcagtctctggagaccatctgcctgctgctggcctataagatcaag
taccccgagaacttcttcctgctccgtgggaaccacgagtgtgccagcatcaaccgcatc
tatggtttctatgatgagtgcaagaggcgctacaacattaaactgtggaaaacctttacc
gactgcttcaactgcctgcccatcgctgccattgtggacgagaaaatcttctgctgccat
ggaggcctgtccccagacctgcagtccatggagcagattcggcgtatcatgaggccaaca
gacgtgcctgaccagggcctgctctgcgacctgctgtggtccgaccctgacaaggacgtg
cagggctggggcgagaatgaccgtggtgtctcctttaccttcggggctgaggtagtggcc
aagttcctgcacaagcacgacctggacctcatctgccgggcgcaccaggtggtggaagac
ggctatgagttctttgccaagcggcagctggtgacactcttctcggctcccaactactgt
ggcgagtttgacaacgcaggcgccatgatgagcgtggatgagacgctcatgtgctccttc
cagatcctcaagcccgccgacaagaacaaggggaaatacgggcagttcagtggcttgaac
cctggaggccggcccatcaccccaccccgcaactccgccaaagccaagaaatag

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