Crocuta crocuta (spotted hyena): 144237912
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Entry
144237912 CDS
T11532
Symbol
NOTCH3
Name
(RefSeq) LOW QUALITY PROTEIN: neurogenic locus notch homolog protein 3
KO
K20995
Notch 3
Organism
ccru Crocuta crocuta (spotted hyena)
Pathway
ccru01522
Endocrine resistance
ccru04330
Notch signaling pathway
ccru04371
Apelin signaling pathway
ccru04658
Th1 and Th2 cell differentiation
ccru04919
Thyroid hormone signaling pathway
ccru05165
Human papillomavirus infection
ccru05200
Pathways in cancer
ccru05206
MicroRNAs in cancer
ccru05224
Breast cancer
Brite
KEGG Orthology (KO) [BR:
ccru00001
]
09130 Environmental Information Processing
09132 Signal transduction
04330 Notch signaling pathway
144237912 (NOTCH3)
04371 Apelin signaling pathway
144237912 (NOTCH3)
09150 Organismal Systems
09151 Immune system
04658 Th1 and Th2 cell differentiation
144237912 (NOTCH3)
09152 Endocrine system
04919 Thyroid hormone signaling pathway
144237912 (NOTCH3)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
144237912 (NOTCH3)
05206 MicroRNAs in cancer
144237912 (NOTCH3)
09162 Cancer: specific types
05224 Breast cancer
144237912 (NOTCH3)
09172 Infectious disease: viral
05165 Human papillomavirus infection
144237912 (NOTCH3)
09176 Drug resistance: antineoplastic
01522 Endocrine resistance
144237912 (NOTCH3)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
EGF
hEGF
EGF_TEN
EGF_CA
Ank_2
Ank
Notch
EGF_2
Ank_4
NODP
Ank_3
NOD
Ank_5
EGF_Teneurin
EGF_3
cEGF
JAG1-like_EGF2
Motif
Other DBs
NCBI-GeneID:
144237912
NCBI-ProteinID:
XP_077627755
LinkDB
All DBs
Position
Unknown
AA seq
2106 aa
AA seq
DB search
MGVVQATKDEAQIQALGDEQIRRKDQKHVWKARARTQQPSPLLVIVGLSWPTAWAWGPGP
GFGAEGRTVVPGGEAEGTFSGSRSSAWARQLCLGLAPAPPCLDGSPCLNGGRCTQLPSRE
AACLCPPGWVGERCQLEDPCHSGPCAGRGVCQSSVVAGTARFSCRCPRGFRGPDCSLPDP
CLSSPCSHGARCSVGPDGRYLCSCPPGYQGRSCRSDVDECRVGGPCRHGGTCLNTPGSFR
CQCPAGYTGPLCENAAVPCAPSPCRNGGTCRQSGDLTYDCACLPGFKGQNCEVNVDDCPG
HRCLNGGTCVDGVNTYNCQCPPEWTGQFCTEDVDECQLQPNACHNGGTCFNTLGGHSCVC
VNGWTGESCSQNIDDCATAVCFHGATCHDRVASFYCACPMGKTGLLCHLDDACVSNPCHE
DAICDTNPVNGRAIXCLPXAGANPCEHLGRCVNTQGSFLCQCGRGYTGPRCETDVNECLS
GPCRNQATCLDRIGQFTCICMAGFTGTYCEVDMDECQSSPCVNGGVCKDRVNGFSCTCPS
GFSGAMCQLDVDECASTPCRNGAKCVDQPDGYECRCAEGFEGTLCERNVDDCSPDPCHHG
RCVDGIASFSCACAPGYTGTRCESQVDECRSQPCRHGGKCLDLVDKYLCRCPPGTTGVNC
EVNIDDCASNPCTFGVCRDGINRYDCVCQPGFTGPLCNVEINECASSPCGDGGSCVDGEN
GFRCLCPPGSLPPLCLPPSHPCAQEPCSHGLCHNAPGGFHCVCEPGWSGPRCSQSLARDA
CESQPCRSGGTCTSDGMGFRCTCPPGVQGRQCELPSPCTPNPCEHGGHCESAPGQLPVCS
CLPGWQGPRCQQDVDECAGPSPCGPHGTCTNLAGSFSCTCHGGYSGPSCDQDIDDCDPNP
CLNGGSCQDGVGSFSCSCLPGFAGPRCARDVDECLSSPCGPGTCTDHVASFTCTCPPGYG
GFRCEQDLPDCSPSSCFHGGTCVDGVNSFSCQCRPGYTGAHCQHEADPCLSRPCLHGGVC
TAAHPGFRCTCPEGFTGAQCQTLVDWCSRAPCQNGGHCARTGTSFYCLCPPGWSGRICDI
RSVPCREAAAQIGVRLEELCQTGGQCVDKDNSHYCVCPEGRTGSHCEQEVDPCSAQRCQH
GGTCRGYMGGYVCECPAGYTGDNCEEDVDECASQPCQNGGFCIDLVARYLCSCPPGTLGV
LCEINEDDCGPGPPLDQGPRCLHNGTCVDLVGGFRCTCPPGYTGLRCEADINECHPGACH
EAHTRDCLQDPGGGFRCLCRTGFTGPRCQTVLSPCESQPCQHGGQCRPSPGPGGMLTFTC
RCIPPFWGPRCERVARSCRELQCPAGVPCQQTVRGPRCACPPGXARASCLASPCLHGGSC
GPAPLAPFFRCACAPGWDGPRCEVPAAAPEAPEEPLCPSAACEAKSGDKRCDRECNSPGC
GWDGGDCSLSVGDPWRQCAALQCWRLFNNSRCDPACSSPACLYDNFDCRAGGRDRACNPV
YEKYCADHFADGRCDQGCNTEECGWDGLDCAAEVPALLARGVLVLTVLLPPEELLRSSAD
FLQRLSGILRTSLRFRLDEHGQAMVFPYHRPGPGPEARNRRELAPEVIGSVVMLEIDNRL
CLQSPENDHCFPDAQSAADYLGALSAVERLDFPYPNMAKSESLMGQVATDWMDTECPEAK
RLKVEDAGAGAEDAVDCRQWTQHHLVAADIRVAPAMALTPPQGDVDADGMDVNVRGPDGF
TPLMLASFCGGALEPVPTEEDEAEDTSASIISDLICQGAQLGARTDRTGETALHLAARYA
RADAAKRLLDAGADTNAQDHSGRTPLHTAVTADAQGVFQILIRNRSTDLDARMADGSTAL
ILAARLAVEGMVEELIASHADVNAVDELGKSALHWAAAVNNVEATLALLKNGANKDMQDS
KEETPLFLAAREGSYEAAKLLLDHFANREITDHLDRLPRDVAQERLHQDIVRLLDQPSGP
RSPPGPHGLGPLLCPPGAFLPGLKVAQSGGKKSRRPPGKAGLGPQGARGRGKKLTLACLG
PXXXXXSLSDWSDSTPSPATATGPAATAAGALPAQPLPLSVPGPLAQAQTQLGPQPEVTP
KRQVLA
NT seq
6315 nt
NT seq
+upstream
nt +downstream
nt
atgggcgtggtccaggccacaaaggatgaggcccaaatccaggctctgggtgacgagcag
atacgaaggaaagaccagaagcacgtttggaaggcacgggcccgcacccagcagccctca
cccctgctggtcattgtcgggctctcatggcccactgcctgggcctgggggcctggcccc
ggctttggtgcagagggcaggactgtggtccctggaggagaagctgagggcacgttctca
ggttcccggtcatcggcctgggcccggcagctgtgtcttggcctggccccagcccccccc
tgcctggacggaagcccgtgcctgaatggaggtcgttgcacccagctgccctcccgggag
gctgcctgcctgtgccctccaggatgggtgggcgagcggtgccagctggaggacccatgc
cattcgggcccctgtgctggccgcggcgtctgccagagctcggtggtggcaggcactgcc
cgcttctcctgccgctgcccgcgtggcttccgaggtcccgactgctccctgccggacccc
tgcctcagcagcccctgtagccacggtgctcgctgctctgtgggacccgatggccggtac
ctctgctcctgcccgcccggctaccagggccgcagctgccgaagcgacgtggatgagtgc
cgcgtgggagggccatgccgccatggtggcacctgcctcaacacgcccgggtccttccgc
tgccagtgccccgctggctacacgggcccactgtgtgagaacgccgcagtgccctgcgcc
ccctcgccgtgccgaaacgggggcacatgtagacagagtggcgatctcacctacgactgc
gcctgcctccctgggttcaagggccagaactgtgaagtgaatgtggacgactgtccaggg
caccgatgtctcaatggcggcacgtgtgtggatggcgtcaacacctacaattgccagtgc
cctcctgaatggacaggccagttctgcacggaggatgtggatgaatgccagctgcagccc
aacgcttgccacaacgggggcacctgcttcaacacactgggcggccacagctgtgtctgc
gtcaatggctggacaggcgagagctgcagtcagaatatcgatgactgtgccacggccgtg
tgcttccacggggccacctgccatgaccgcgtggcttcgttctactgtgcctgtcccatg
ggcaagactgggcttctgtgtcatctggatgatgcctgtgtcagcaatccctgtcacgag
gatgctatctgtgacacgaacccagtgaatggacgggccatcngatgcctccttgcaggc
gccaacccgtgtgagcacctgggccggtgtgtgaacacacagggctccttcctgtgccag
tgtggccgtgggtacaccggcccgcgctgcgagactgatgtcaacgagtgcctatcgggg
ccctgccgcaaccaggccacatgccttgaccgcataggccagttcacctgcatctgcatg
gcaggctttacaggcacttattgcgaggtggacatggatgagtgtcaaagcagcccatgt
gtcaatggcggggtctgcaaggacagagtcaacggcttcagctgcacctgcccttcaggc
ttcagcggggccatgtgtcagctggatgtggatgagtgcgcgagcacaccctgccggaac
ggagccaaatgtgtggatcagcccgacggttacgaatgccgctgcgcagagggctttgaa
ggcactctgtgtgagcgcaacgtggatgactgctccccggacccgtgccaccacgggcgc
tgcgtagatggcattgccagcttctcgtgcgcctgtgccccgggatacacaggcacgcgc
tgtgagagccaggtggacgagtgccgcagccagccctgccgccacggaggcaaatgtcta
gacttggtggacaagtatctctgccgctgccctcctggcaccacaggagtgaactgcgag
gtgaacattgatgattgtgccagcaacccctgcacctttggagtctgccgggatggcatc
aaccgctatgactgtgtctgccagcctggcttcacagggcccctttgcaacgtggagatc
aacgagtgtgcgtccagcccgtgcggtgacggaggctcctgtgtggatggggaaaatggc
ttccgctgcctctgcccccctggctccctgcccccgctctgccttcccccgagccatccc
tgtgcccaagagccctgcagtcacggcctctgccacaacgcacctggagggttccactgc
gtgtgtgagcctggctggagcggcccccgatgcagccagagccttgctcgagatgcctgt
gaatcccagccctgccggtctggcggcacttgtaccagcgatggaatgggcttccgctgc
acctgtccccctggtgtccagggccgtcagtgtgagctgccatccccctgtaccccaaac
ccctgtgagcatgggggccactgcgagtctgcccctggccagctgcctgtgtgctcctgc
ctccctggatggcaaggcccacgatgccagcaggatgtggatgaatgtgctggcccctcg
ccctgtggcccccacgggacttgcaccaacctggcggggagtttcagctgcacctgccat
ggggggtacagcggcccctcctgtgatcaggacatcgatgactgtgaccccaacccctgc
ctgaatggtggctcctgccaggatggcgtgggctccttttcatgctcctgcctccctggc
tttgccggtccccgctgtgcccgcgacgtggacgagtgtctgagcagcccctgtggcccg
ggcacctgcaccgaccacgtggcctcctttacctgcacctgcccacctggatatggtggc
ttccgctgtgagcaggacctacccgactgcagccccagctcctgcttccacggcgggacc
tgcgtggacggcgtgaattcgttcagctgccagtgccgccccggctacacgggcgcacac
tgccaacacgaggccgacccctgcctctctcggccctgcctgcatgggggcgtctgcact
gccgcccaccccggcttccgctgcacctgccccgagggcttcactggcgctcagtgccag
acactggtagactggtgcagccgcgcgccctgtcagaacgggggtcactgtgcccggacc
gggacctccttctactgcctttgccctccggggtggagcggccgcatctgtgacatccgg
agcgtgccctgcagggaggctgcagcccagatcggggtgcggctggaagagctgtgtcag
actggtgggcagtgtgtggacaaggacaattcccactattgcgtgtgtccggaaggccgc
accggaagccactgtgagcaggaggtggacccctgctctgcccagcgctgccagcacggg
ggcacctgccgtggctacatgggtggttatgtgtgcgagtgtccagctggctacactggg
gacaactgtgaggaggatgtggatgagtgtgcctcccagccctgccagaacgggggcttc
tgcattgacctcgtggcccgctatctctgctcctgccccccgggaacgctgggcgtgctc
tgtgagattaatgaggatgattgtggcccaggcccgcccctggaccagggcccccgctgc
ctgcacaatggtacctgcgtggacctcgtgggtggcttccgctgcacctgcccccccggg
tacaccggcctgcgctgtgaggcagacatcaatgagtgtcacccgggtgcctgccacgag
gcacacactcgggattgtctgcaggacccaggtgggggcttccgctgcctctgtcgtact
ggcttcacaggtccccgctgtcagaccgtcctgtctccctgcgagtcccagccatgccag
cacggaggccagtgccgtcccagcccaggacctgggggcatgctgacatttacctgccgc
tgcattccaccattctggggcccgcgttgcgagcgggtggcgcgctcctgccgggagctg
cagtgcccggcaggcgtcccgtgccagcagacggtccgtgggccgcgctgcgcctgcccc
ccggcngccagggccagctgcctggcctccccctgcctccacggcggctcctgcggccca
gcgccccttgcacctttcttccgttgcgcgtgcgcgccaggctgggatggaccgcgctgc
gaggtgcccgcggcggcgcccgaggcccctgaggagccgctgtgcccgagcgccgcctgc
gaggccaagagcggggacaagcgctgcgaccgcgagtgcaacagcccgggctgcggctgg
gacggcggcgactgctcgctgagcgtgggcgacccctggcggcagtgcgcggcgctgcag
tgctggcgcctcttcaacaacagccgctgcgaccccgcctgcagctcgcccgcctgcctc
tatgacaacttcgattgccgcgcgggcggccgggaccgcgcctgcaaccccgtgtacgag
aagtactgcgcggaccacttcgcggacggccgctgcgaccagggctgcaacacggaggag
tgcggctgggacgggctggactgcgcggccgaggtgcccgcgctgctggcccgcggggtg
ctggtgctcaccgtgctgctgccgcccgaggagctgctgcgctccagcgccgacttcctg
cagcggctgagcggcatcctgcgcacgtcgctgcgcttccgcctggacgagcacggtcag
gccatggtcttcccgtaccaccggcccggccccggccccgaagcccggaaccggcgggag
ctggccccggaggtgatcggctctgtggtgatgctggagatcgacaaccggctgtgcctg
cagtcgcccgagaatgaccactgcttccccgacgcccagagtgcggccgactacctggga
gccctgtcggcggtggagcgccttgacttcccgtacccgaacatggccaagagcgagagt
ctcatggggcaggtggccacagactggatggatacggagtgcccagaagcaaagcgactg
aaggtagaggatgctggcgcgggggccgaggatgccgtggactgccgccagtggacgcaa
caccacctggttgccgcggacatccgtgtggcaccagccatggccttgacgcccccacag
ggcgacgtggatgccgacggcatggacgtcaatgtgcgtggcccagacggcttcacccct
ctgatgctggcctccttctgtgggggggctctggagcccgtgcccaccgaagaggacgag
gcggaagacacgtcagccagcatcatctcggacttgatctgccagggagcccagcttggg
gcaaggacggaccgcacgggcgagacggccctgcacctggctgcccgctacgcccgggcc
gatgcggccaagcggctgctggatgctggggcggacaccaatgcccaggaccattcaggc
cgcactcctctgcacactgctgtcaccgctgatgcccagggcgtcttccagattctcatc
cggaaccgatccacagacctggatgcccgcatggcggatggctcaacagcactaatcctg
gcagcccgcctggcggtggagggcatggtggaagagctcattgccagccatgccgatgtc
aatgcggtggatgagcttgggaaatcagccttacactgggcagcagccgtcaacaatgtg
gaggccaccttggccctgctgaaaaatggagccaacaaggacatgcaggatagcaaggag
gaaacgccgctgtttctggccgcccgagagggcagctatgaggctgccaagctgctgctg
gaccacttcgccaaccgcgagatcacagaccacctggacaggctgccgcgggatgtggcc
caggagcggctgcaccaggacatcgtgcgcttgctggaccagcccagtgggccccggagc
cctcccggcccgcacggcctggggcccctcctctgccctccgggggccttcctcccgggc
ctcaaggtggcacagtctgggggcaagaagagccggaggccgccggggaaggcggggctg
gggccgcagggcgcccgggggcggggcaagaagctgacgctggcctgcctggggcccnnn
nnnnnnnnnnnntccctctcggactggtcagactccacgcccagcccagccacggccacc
gggcccgcggccacagccgctggggcactgcccgcccagccgctgcccctttccgtccca
ggccccctagctcaggcccagacccagctggggccccagcccgaagtcacccccaagagg
caggtgttggcctga
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