KEGG   Crocuta crocuta (spotted hyena): 144239539
Entry
144239539         CDS       T11532                                 
Symbol
BCKDHA
Name
(RefSeq) LOW QUALITY PROTEIN: 2-oxoisovalerate dehydrogenase subunit alpha, mitochondrial
  KO
K00166  2-oxoisovalerate dehydrogenase E1 component subunit alpha [EC:1.2.4.4]
Organism
ccru  Crocuta crocuta (spotted hyena)
Pathway
ccru00280  Valine, leucine and isoleucine degradation
ccru00640  Propanoate metabolism
ccru00785  Lipoic acid metabolism
ccru01100  Metabolic pathways
ccru01210  2-Oxocarboxylic acid metabolism
Module
ccru_M00036  Leucine degradation, leucine => acetoacetate + acetyl-CoA
Brite
KEGG Orthology (KO) [BR:ccru00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00640 Propanoate metabolism
    144239539 (BCKDHA)
  09105 Amino acid metabolism
   00280 Valine, leucine and isoleucine degradation
    144239539 (BCKDHA)
  09108 Metabolism of cofactors and vitamins
   00785 Lipoic acid metabolism
    144239539 (BCKDHA)
Enzymes [BR:ccru01000]
 1. Oxidoreductases
  1.2  Acting on the aldehyde or oxo group of donors
   1.2.4  With a disulfide as acceptor
    1.2.4.4  3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring)
     144239539 (BCKDHA)
SSDB
Motif
Pfam: E1_dh TPP_enzyme_C DXP_synthase_N
Other DBs
NCBI-GeneID: 144239539
NCBI-ProteinID: XP_077629735
LinkDB
Position
Unknown
AA seq 438 aa
MAVAAAAKLWGSGRGLGRAGHLLLRRFGARGLARYHPQRQEQQQHFLSPDDKPQFPGASA
EFVDKLEFIQPNVISGIPVYRVMDRQGQIINPSEDPHLPQETVLKFYKSMTLLNTMDRIL
YESQRQGRISFYMTNYGEEGTHVGSAAALDSMDLVFGQYREAGVLMYRDYPLELFMAQCY
GNVSDPGKGRQMPVHYGCKERHFVTISSPLATQIPQAVGAAYAAKRANTNRVVICYFGEG
AASEGDAHAGFNFAATLECPVIFFCLSPGAXPASVPTAARGPGYGIMSIRVDGNDVFAVY
NATKEARRRAVAENQPFLIEAMTYRIGHHSTSDDSSAYRSVDEVNYWDKQDHPISRLRHY
LQGRGWWDDEQEKAWRKQSRRKVMEAFEQAERKPKPNPNLLFSDVYQEMPTQLRKQQESL
ARHLQTYGEHYPLDHFEK
NT seq 1317 nt   +upstreamnt  +downstreamnt
atggcggtggcggcggcggcgaagctctggggctcaggtcgaggcttgggccgggctggc
cacctgctcctgcggcggtttggtgctcgggggctggctagatatcacccccagagacag
gagcagcagcagcacttcctgtccccggatgacaagccccagttcccgggggcctcggcg
gagtttgtggacaagctcgaattcatccagcccaatgtcatctctgggatccccgtctac
cgcgtcatggaccggcagggccagatcatcaaccccagcgaggatccccacctgccccag
gagacggtgctcaagttctacaagagcatgactctgctcaacaccatggaccgcatcctc
tacgagtcccagcggcagggccggatctccttctacatgaccaactatggcgaggagggg
acacacgtggggagcgcagcagcgctggacagcatggacctggtgttcggccagtaccgg
gaggcaggcgtgctcatgtaccgggactaccctctggagctgttcatggcccagtgctac
ggcaacgtgagcgacccgggcaaggggcgccagatgcccgtgcactacggctgcaaggag
cgccacttcgtcaccatctcttctccactggccacgcagatcccgcaggcggtgggggcg
gcctacgcggccaagcgtgccaacaccaacagagtggtcatctgttacttcggggagggg
gcggccagcgagggggatgcccacgccggcttcaacttcgctgccaccctcgagtgcccc
gtcatcttcttctgtctgagccctggggcctgacctgcctctgtccccacagctgctcga
ggcccgggctacggcatcatgtccatccgcgtggacggcaatgacgtgttcgccgtgtac
aacgccaccaaggaggcccggcggcgggctgtggccgagaaccagcccttcctcattgag
gccatgacctacaggatcgggcaccacagcaccagtgacgacagctcggcctaccgctcg
gtggatgaggtcaattactgggacaagcaggaccaccccatctcccggctgcggcactac
ttgcagggccgaggctggtgggacgacgagcaggagaaggcctggagaaagcagtcccgc
aggaaggtgatggaggcctttgagcaggcggagcggaagccgaagcccaaccccaacctg
ctcttctcggacgtgtaccaggagatgcccacccagcttcgcaagcagcaggagtccctg
gcccggcacctccagacctacggcgagcactaccccctggaccacttcgagaagtga

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