Crocuta crocuta (spotted hyena): 144240021
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Entry
144240021 CDS
T11532
Symbol
IDH2
Name
(RefSeq) isocitrate dehydrogenase [NADP], mitochondrial
KO
K00031
isocitrate dehydrogenase [EC:
1.1.1.42
]
Organism
ccru Crocuta crocuta (spotted hyena)
Pathway
ccru00020
Citrate cycle (TCA cycle)
ccru00480
Glutathione metabolism
ccru01100
Metabolic pathways
ccru01200
Carbon metabolism
ccru01210
2-Oxocarboxylic acid metabolism
ccru01230
Biosynthesis of amino acids
ccru04146
Peroxisome
ccru05230
Central carbon metabolism in cancer
Module
ccru_M00009
Citrate cycle (TCA cycle, Krebs cycle)
ccru_M00010
Citrate cycle, first carbon oxidation, oxaloacetate => 2-oxoglutarate
Brite
KEGG Orthology (KO) [BR:
ccru00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00020 Citrate cycle (TCA cycle)
144240021 (IDH2)
09106 Metabolism of other amino acids
00480 Glutathione metabolism
144240021 (IDH2)
09140 Cellular Processes
09141 Transport and catabolism
04146 Peroxisome
144240021 (IDH2)
09160 Human Diseases
09161 Cancer: overview
05230 Central carbon metabolism in cancer
144240021 (IDH2)
Enzymes [BR:
ccru01000
]
1. Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.1.1 With NAD+ or NADP+ as acceptor
1.1.1.42 isocitrate dehydrogenase (NADP+)
144240021 (IDH2)
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Paralog
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Motif
Pfam:
Iso_dh
Motif
Other DBs
NCBI-GeneID:
144240021
NCBI-ProteinID:
XP_077630389
LinkDB
All DBs
Position
Unknown
AA seq
433 aa
AA seq
DB search
MDGDEMTRIIWQFIKEKLILPHVDVQLKYFDLGLPNRDQTNDQVTIDSALATQKYSVAVK
CATITPDEARVEEFKLKKMWKSPNGTIRNILGGTVFREPIICKNIPRLVPGWTKPITIGR
HAHGDQYKATDFVVDRAGTFKIVFSPKDGSGAKEWEVYNFPAGGVGMGMYNTDESISGFA
HSCFQYAIQKKWPLYMSTKNTILKAYDGRFKDIFQEIFEKHYKTDFDKNKIWYEHRLIDD
MVAQVLKSSGGFVWACKNYDGDVQSDILAQGFGSLGLMTSVLVCPDGKTIEAEAAHGTVT
RHYREHQKGRPTSTNPIASIFAWTRGLEHRGKLDGNQDLIRFAQTLEKVCVQTVESGAMT
KDLAGCIHGLSNVKLNEHFLNTSDFLDTIKNNLDKALVSGVGGGGDSGLLKPESWDLRSS
DGFSPPLPLVASV
NT seq
1302 nt
NT seq
+upstream
nt +downstream
nt
atggacggcgatgagatgacccggatcatctggcagttcatcaaggagaagctcatcctg
ccgcacgtggacgtccagctcaagtattttgacctggggctcccaaaccgtgaccagacc
aacgaccaggtcaccatagactccgcgttggccacccagaagtacagtgtggctgtcaaa
tgtgccaccatcacccccgatgaagcccgggtggaagagttcaagctgaagaagatgtgg
aagagtcccaatggaaccatccgaaacatcctaggagggactgtcttccgggaacccatc
atctgcaaaaacatcccacgcctcgtcccgggctggaccaagcccatcaccatcggcagg
cacgcccacggcgaccagtacaaggctacagacttcgtggtcgaccgggccggcacgttc
aagattgtcttctccccgaaggacggcagcggcgctaaggagtgggaggtgtacaatttc
ccggccggcggcgtggggatgggcatgtataacacggacgagtccatctcaggctttgcg
cacagctgtttccagtacgccatccagaagaaatggccgctatacatgagcaccaagaac
accattctgaaggcctatgacgggcgcttcaaggacatcttccaggaaatctttgagaag
cactataagaccgacttcgacaagaataagatctggtacgagcaccggctcatcgatgac
atggtggctcaggtcctcaagtcttcaggcggcttcgtgtgggcctgcaagaactacgat
ggagatgtgcagtcagacatcctggcgcagggctttggctcccttggcctgatgacgtct
gtgctggtctgcccggatgggaagaccattgaggctgaggctgctcatgggacggtcacc
cgccattatagggagcaccagaagggccggcctactagcaccaaccccatcgccagcatc
tttgcctggacgcgcggcctggagcaccggggaaagctggacgggaaccaggacctcatc
aggtttgcacagaccctggagaaggtgtgtgtccagacagtggagagcggagccatgacc
aaggacctggccggctgcatccacggcctcagcaatgtgaagctgaacgagcacttcctg
aacacgtcggacttcctggacaccatcaagaacaacctggacaaggccctggtttccggc
gttgggggcgggggagactctgggctcctgaaaccggagagctgggacctccgcagctca
gatgggttctccccgccgctccccctggtggcctccgtctga
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