Crocuta crocuta (spotted hyena): 144240455
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Entry
144240455 CDS
T11532
Symbol
HPSE
Name
(RefSeq) heparanase
KO
K07964
heparanase [EC:
3.2.1.166
]
Organism
ccru Crocuta crocuta (spotted hyena)
Pathway
ccru00531
Glycosaminoglycan degradation
ccru01100
Metabolic pathways
ccru05205
Proteoglycans in cancer
Module
ccru_M00078
Heparan sulfate degradation
Brite
KEGG Orthology (KO) [BR:
ccru00001
]
09100 Metabolism
09107 Glycan biosynthesis and metabolism
00531 Glycosaminoglycan degradation
144240455 (HPSE)
09160 Human Diseases
09161 Cancer: overview
05205 Proteoglycans in cancer
144240455 (HPSE)
09180 Brite Hierarchies
09183 Protein families: signaling and cellular processes
00536 Glycosaminoglycan binding proteins [BR:
ccru00536
]
144240455 (HPSE)
Enzymes [BR:
ccru01000
]
3. Hydrolases
3.2 Glycosylases
3.2.1 Glycosidases, i.e. enzymes that hydrolyse O- and S-glycosyl compounds
3.2.1.166 heparanase
144240455 (HPSE)
Glycosaminoglycan binding proteins [BR:
ccru00536
]
Heparan sulfate / Heparin
Enzymes
144240455 (HPSE)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
Glyco_hydro_79n
Motif
Other DBs
NCBI-GeneID:
144240455
NCBI-ProteinID:
XP_077630917
LinkDB
All DBs
Position
Unknown
AA seq
545 aa
AA seq
DB search
MLLRWQPGLPLPQPQLLLLLGSLAPFSLRAPVALAQAEDPVALDFSTERPVHLVSPAFLS
FTIDANLATDPRFLTFLGSTKLRTLARGLSPAFLRFGGTKTDFLIFDPKKEPTFEERSYW
QSQVNQDICKSGSIPSDVEKRLQLEWPFQEQLLLREQYQKKFKNSTYSRSSVDMLYTFAN
CSGLDLIFGLNALLRTADLQWNSSNAQLLLDYCSSKNYNISWELGNEPNSFRKKAGIFID
GLQLGEDFVKLHKLLGKSTFETANLYGPDIGQPRGKTVKMLTSFLKAGGEVIDSVTWHHY
YVNGRIATKEDFLNPDVLDTFTSSVQKIFQVVEETRPHKKVWLGETSSAYGGGAPLLSNT
YAAGFMWLDKLGLSARMGIEVVMRQVLFGAGNYHLVDQNFKPLPDYWLSLLFKKLVGTHV
LMVRVKGPDSSKLRVYLHCTNINHPRYKAGDLTLYALNLHNVTKRLQLPYHLFDKEVDKY
LVKPLGPDGLLSKSVQLNGQTLKMVDDHTLPALTEKPLRPGSTLGLPAFSYGFFVIRNAK
VTACL
NT seq
1638 nt
NT seq
+upstream
nt +downstream
nt
atgctgctgcgctggcagccggggctgccgctgccgcagccgcagctgctgctgctcctg
gggtcgctcgctcccttctccctgcgcgcgccggtggccctcgcgcaggccgaggacccc
gtggcgctggacttctccaccgagcggccggtgcacctggtgagtcccgccttcctgtcc
ttcaccatcgacgccaacctggccacggacccgcggttcctcaccttcctgggttccaca
aagcttcgcactttggccagaggtttgtctcctgcgttcctgagatttggtggcaccaag
acagacttcctcatttttgatcccaagaaagaaccaacctttgaagagagaagttactgg
cagtctcaagtcaaccaggatatttgtaaatctggatccatcccttctgatgtagagaag
agattacagttggaatggcccttccaggagcaattgctactcagagaacagtatcagaag
aagttcaaaaacagcacttactcaaggagctccgtggatatgctgtacacttttgcaaat
tgctcaggactggacttgatctttggtctaaatgccttactacgaacagcagatttgcag
tggaacagttccaatgctcagttgctcctggattattgctcttctaagaattataacatt
tcttgggaactaggcaatgaacctaacagtttccggaagaaggctggtattttcatcgat
ggattgcagttaggagaagattttgtcaagttgcataaacttctaggaaaatccactttc
gaaactgcgaatctctatggtcctgatattggccagcctcgaggaaagactgtcaagatg
ctaacgagtttcctgaaggctgggggagaagtgattgattcagttacatggcaccactac
tacgtgaatggacgaattgctaccaaagaggattttctaaaccctgatgtgttagacact
tttacttcatctgtgcaaaaaattttccaggttgttgaggagaccagacctcacaagaag
gtttggttaggagaaacgagctctgcgtacgggggtggagcgccactgctgtccaacacg
tatgcggctggctttatgtggctggataaactgggcctgtccgccagaatgggcatagaa
gtggtgatgaggcaagtgctctttggagctggaaactaccacttagtggatcaaaacttc
aaacctttacctgattattggctatctcttctgttcaagaaattggtaggcacccatgta
ttaatggtgagagtgaaaggtccagacagcagcaaacttcgagtataccttcactgtacc
aacatcaatcacccaaggtataaagcaggagatttaaccctgtatgccttaaacctccat
aatgtcaccaaacgcttgcagttgccatatcatttatttgacaaagaagtggacaaatac
ctcgtaaaacctttagggcctgatggattactttctaaatctgtccaactcaacggtcaa
actctgaagatggtagatgatcacactctcccagctttgacagaaaaacctctccgccca
ggaagtacactgggcttgccagctttctcctatgggttttttgtgataaggaatgccaaa
gttaccgcttgcctctga
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