KEGG   Crocuta crocuta (spotted hyena): 144242191
Entry
144242191         CDS       T11532                                 
Symbol
GNAI2
Name
(RefSeq) guanine nucleotide-binding protein G(i) subunit alpha-2
  KO
K04630  guanine nucleotide-binding protein G(i) subunit alpha
Organism
ccru  Crocuta crocuta (spotted hyena)
Pathway
ccru04015  Rap1 signaling pathway
ccru04022  cGMP-PKG signaling pathway
ccru04024  cAMP signaling pathway
ccru04062  Chemokine signaling pathway
ccru04071  Sphingolipid signaling pathway
ccru04081  Hormone signaling
ccru04082  Neuroactive ligand signaling
ccru04261  Adrenergic signaling in cardiomyocytes
ccru04360  Axon guidance
ccru04371  Apelin signaling pathway
ccru04540  Gap junction
ccru04611  Platelet activation
ccru04670  Leukocyte transendothelial migration
ccru04713  Circadian entrainment
ccru04723  Retrograde endocannabinoid signaling
ccru04724  Glutamatergic synapse
ccru04725  Cholinergic synapse
ccru04726  Serotonergic synapse
ccru04727  GABAergic synapse
ccru04728  Dopaminergic synapse
ccru04730  Long-term depression
ccru04914  Progesterone-mediated oocyte maturation
ccru04915  Estrogen signaling pathway
ccru04916  Melanogenesis
ccru04921  Oxytocin signaling pathway
ccru04923  Regulation of lipolysis in adipocytes
ccru04924  Renin secretion
ccru04926  Relaxin signaling pathway
ccru04928  Parathyroid hormone synthesis, secretion and action
ccru04934  Cushing syndrome
ccru04935  Growth hormone synthesis, secretion and action
ccru04971  Gastric acid secretion
ccru05012  Parkinson disease
ccru05030  Cocaine addiction
ccru05032  Morphine addiction
ccru05034  Alcoholism
ccru05133  Pertussis
ccru05142  Chagas disease
ccru05145  Toxoplasmosis
ccru05163  Human cytomegalovirus infection
ccru05170  Human immunodeficiency virus 1 infection
ccru05200  Pathways in cancer
ccru05207  Chemical carcinogenesis - receptor activation
Brite
KEGG Orthology (KO) [BR:ccru00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04015 Rap1 signaling pathway
    144242191 (GNAI2)
   04371 Apelin signaling pathway
    144242191 (GNAI2)
   04071 Sphingolipid signaling pathway
    144242191 (GNAI2)
   04024 cAMP signaling pathway
    144242191 (GNAI2)
   04022 cGMP-PKG signaling pathway
    144242191 (GNAI2)
  09133 Signaling molecules and interaction
   04082 Neuroactive ligand signaling
    144242191 (GNAI2)
   04081 Hormone signaling
    144242191 (GNAI2)
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04540 Gap junction
    144242191 (GNAI2)
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    144242191 (GNAI2)
   04670 Leukocyte transendothelial migration
    144242191 (GNAI2)
   04062 Chemokine signaling pathway
    144242191 (GNAI2)
  09152 Endocrine system
   04923 Regulation of lipolysis in adipocytes
    144242191 (GNAI2)
   04915 Estrogen signaling pathway
    144242191 (GNAI2)
   04914 Progesterone-mediated oocyte maturation
    144242191 (GNAI2)
   04921 Oxytocin signaling pathway
    144242191 (GNAI2)
   04926 Relaxin signaling pathway
    144242191 (GNAI2)
   04935 Growth hormone synthesis, secretion and action
    144242191 (GNAI2)
   04928 Parathyroid hormone synthesis, secretion and action
    144242191 (GNAI2)
   04916 Melanogenesis
    144242191 (GNAI2)
   04924 Renin secretion
    144242191 (GNAI2)
  09153 Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    144242191 (GNAI2)
  09154 Digestive system
   04971 Gastric acid secretion
    144242191 (GNAI2)
  09156 Nervous system
   04724 Glutamatergic synapse
    144242191 (GNAI2)
   04727 GABAergic synapse
    144242191 (GNAI2)
   04725 Cholinergic synapse
    144242191 (GNAI2)
   04728 Dopaminergic synapse
    144242191 (GNAI2)
   04726 Serotonergic synapse
    144242191 (GNAI2)
   04730 Long-term depression
    144242191 (GNAI2)
   04723 Retrograde endocannabinoid signaling
    144242191 (GNAI2)
  09158 Development and regeneration
   04360 Axon guidance
    144242191 (GNAI2)
  09159 Environmental adaptation
   04713 Circadian entrainment
    144242191 (GNAI2)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    144242191 (GNAI2)
   05207 Chemical carcinogenesis - receptor activation
    144242191 (GNAI2)
  09172 Infectious disease: viral
   05170 Human immunodeficiency virus 1 infection
    144242191 (GNAI2)
   05163 Human cytomegalovirus infection
    144242191 (GNAI2)
  09171 Infectious disease: bacterial
   05133 Pertussis
    144242191 (GNAI2)
  09174 Infectious disease: parasitic
   05145 Toxoplasmosis
    144242191 (GNAI2)
   05142 Chagas disease
    144242191 (GNAI2)
  09164 Neurodegenerative disease
   05012 Parkinson disease
    144242191 (GNAI2)
  09165 Substance dependence
   05030 Cocaine addiction
    144242191 (GNAI2)
   05032 Morphine addiction
    144242191 (GNAI2)
   05034 Alcoholism
    144242191 (GNAI2)
  09167 Endocrine and metabolic disease
   04934 Cushing syndrome
    144242191 (GNAI2)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04147 Exosome [BR:ccru04147]
    144242191 (GNAI2)
   04031 GTP-binding proteins [BR:ccru04031]
    144242191 (GNAI2)
Exosome [BR:ccru04147]
 Exosomal proteins
  Proteins found in most exosomes
   144242191 (GNAI2)
GTP-binding proteins [BR:ccru04031]
 Heterotrimeric G-proteins
  Alpha Subunits
   Alpha type 1 (Gi/o) [OT]
    144242191 (GNAI2)
SSDB
Motif
Pfam: G-alpha Arf Gtr1_RagA Roc TniB GTP_EFTU AAA_16 FtsK_SpoIIIE AAA_29
Other DBs
NCBI-GeneID: 144242191
NCBI-ProteinID: XP_077633126
LinkDB
Position
Unknown
AA seq 355 aa
MGCTVSAEDKAAAERSKMIDKNLREDGEKAAREVKLLLLGAGESGKSTIVKQMKIIHEDG
YSEEECRQYRAVVYSNTIQSIMAIVKAMGNLQIDFADPSRADDARQLFALSCTAEEQGVL
PEDLSGVIRRLWADHGVQACFGRSREYQLNDSAAYYLNDLERIAQSDYIPTQQDVLRTRV
KTTGIVETHFTFKDLHFKMFDVGGQRSERKKWIHCFEGVTAIIFCVALSAYDLVLAEDEE
MNRMHESMKLFDSICNNKWFTDTSIILFLNKKDLFEEKITHSPLTICFPEYTGANKYDEA
ASYIQSKFEDLNKRKDTKEIYTHFTCATDTKNVQFVFDAVTDVIIKNNLKDCGLF
NT seq 1068 nt   +upstreamnt  +downstreamnt
atgggctgcaccgtgagtgccgaggacaaggcggcggccgagcgctctaagatgatcgac
aagaacctgcgggaagacggcgagaaggcggcgcgggaggtgaagttgctgcttttgggt
gctggagagtcagggaagagcaccattgtcaagcagatgaagatcatccacgaggatggc
tattccgaggaggagtgccggcagtaccgggcggttgtctacagcaacaccatccagtcc
atcatggccattgtcaaagccatgggcaatctgcagattgactttgccgacccctcccga
gcggatgatgccaggcagctgtttgcactgtcctgcactgctgaggagcaaggcgtgctt
cctgaggatctgtccggtgtcatccggaggctctgggctgaccacggagtgcaggcttgc
tttggccgctctcgggagtaccagctcaatgactctgctgcctactacctgaatgacctg
gagcgcattgcacagagtgactacatccccacacagcaggatgtgctgcggacccgtgtg
aagaccacgggcattgtggagacgcacttcactttcaaggaccttcatttcaagatgttt
gatgtgggcggtcagcggtctgagcggaagaagtggatccactgctttgagggtgtcaca
gccatcatcttctgcgtagccttgagcgcctatgacctggtgctagctgaggacgaggag
atgaaccgcatgcacgagagcatgaagctgtttgacagtatctgcaacaacaagtggttc
acagacacgtccatcatcctcttcctcaacaagaaggacctgtttgaggagaagatcaca
cacagccccctgaccatctgcttccctgagtacacaggggccaacaagtacgacgaggca
gccagctacattcagagtaagtttgaggacctgaacaagcgcaaggacaccaaggagatc
tacacgcacttcacgtgcgccaccgacaccaagaacgtgcagtttgtgtttgatgccgtc
accgacgtcatcatcaagaacaacctgaaggactgcggcctcttctga

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