KEGG   Crocuta crocuta (spotted hyena): 144243953
Entry
144243953         CDS       T11532                                 
Symbol
BECN1
Name
(RefSeq) beclin-1 isoform X1
  KO
K08334  beclin
Organism
ccru  Crocuta crocuta (spotted hyena)
Pathway
ccru04136  Autophagy - other
ccru04137  Mitophagy - animal
ccru04140  Autophagy - animal
ccru04145  Phagocytosis
ccru04215  Apoptosis - multiple species
ccru04371  Apelin signaling pathway
ccru05010  Alzheimer disease
ccru05014  Amyotrophic lateral sclerosis
ccru05016  Huntington disease
ccru05017  Spinocerebellar ataxia
ccru05022  Pathways of neurodegeneration - multiple diseases
ccru05167  Kaposi sarcoma-associated herpesvirus infection
Brite
KEGG Orthology (KO) [BR:ccru00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04371 Apelin signaling pathway
    144243953 (BECN1)
 09140 Cellular Processes
  09141 Transport and catabolism
   04145 Phagocytosis
    144243953 (BECN1)
   04140 Autophagy - animal
    144243953 (BECN1)
   04136 Autophagy - other
    144243953 (BECN1)
   04137 Mitophagy - animal
    144243953 (BECN1)
  09143 Cell growth and death
   04215 Apoptosis - multiple species
    144243953 (BECN1)
 09160 Human Diseases
  09172 Infectious disease: viral
   05167 Kaposi sarcoma-associated herpesvirus infection
    144243953 (BECN1)
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    144243953 (BECN1)
   05014 Amyotrophic lateral sclerosis
    144243953 (BECN1)
   05016 Huntington disease
    144243953 (BECN1)
   05017 Spinocerebellar ataxia
    144243953 (BECN1)
   05022 Pathways of neurodegeneration - multiple diseases
    144243953 (BECN1)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:ccru04131]
    144243953 (BECN1)
   03029 Mitochondrial biogenesis [BR:ccru03029]
    144243953 (BECN1)
Membrane trafficking [BR:ccru04131]
 Autophagy
  Autophagosome formation proteins
   PI3K complex
    144243953 (BECN1)
Mitochondrial biogenesis [BR:ccru03029]
 Mitochondrial quality control factors
  Mitophagy factors
   Autophagy-related proteins
    144243953 (BECN1)
SSDB
Motif
Pfam: APG6 APG6_N BH3 NDC80_loop HAUS-augmin3 CC_Bre1 MT FPP LMBR1 V_ATPase_I DUF4200
Other DBs
NCBI-GeneID: 144243953
NCBI-ProteinID: XP_077635223
LinkDB
Position
Unknown
AA seq 448 aa
MEGSKTSSSTMQVSFVCQRCSQPLKLDTSFKILDRVTIQELTAPLLATAQAKPGETQEEE
ANSGEEPFIETRQDGVSRRFIPPARMMSTESANSFTLIGEASDGGTMENLSRRLKVTGDL
FDIMSGQTDVDHPLCEECTDTLLDQLDTQLNVTENECQNYKRCLEILEQMNEDDSEQLQM
ELKELALEEERLIQELEDVEKNRKLVAENLEKVQAEAERLDQEEAQYQREYSEFKRQQLE
LDDELKSVENQMRYAQIQLDKLKKTNVFNATFHIWHSGQFGTINNFRLGRLPSVPVEWNE
INAAWGQTVLLLHALANKMGLKFQRYRLVPYGNHSYLESLTDKSKELPLYCSGGLRFFWD
NKFDHAMVAFLDCVQQFKEEVEKGETRFCLPYRMDVEKGKIEDTGGSGGSYSIKTQFNSE
EQWTKALKFMLTNLKWGLAWVSSQFYNK
NT seq 1347 nt   +upstreamnt  +downstreamnt
atggaggggtctaaaacgtccagcagcaccatgcaggtgagcttcgtgtgccagcgctgc
agccagcccctgaaactggacacgagcttcaagatcctggaccgtgtcactatccaggag
ctcacagctccattacttgccacagcccaggcgaaaccaggagagacccaagaggaagag
gctaactcaggagaagagccatttattgaaactcgccaggatggtgtctctcgcagattc
atccccccagccaggatgatgtccacagaaagtgccaacagcttcactctgatcggggag
gcatctgacggcggcaccatggagaacctcagccgaagactgaaggtcactggggacctt
tttgacatcatgtcaggccagacagatgtggatcacccgctgtgtgaggaatgcacagat
actcttttagaccaactggacactcagctcaacgtcactgaaaatgagtgtcagaactac
aaacgctgtttagagatcttagagcagatgaacgaggatgacagtgagcagctgcagatg
gagctaaaggagctggcgttagaggaggagaggctgatccaggagctggaagatgtggaa
aagaaccgcaagttagtggcagagaatctcgagaaggtccaggctgaggctgagagactg
gatcaggaggaagctcagtatcagagggaatacagtgaatttaagcgacagcagctggag
ctggacgatgagctgaagagtgtggaaaaccagatgcgttacgcccagatacagctggac
aagctgaagaaaaccaatgtctttaatgcaaccttccacatctggcacagtggacagttt
ggcaccatcaataacttccgactgggtcgcctgcccagtgttcctgtggaatggaatgag
atcaacgctgcgtggggccagacggtgctgctgctccatgccctggccaataagatgggt
ctgaaatttcagaggtatcgacttgttccctacggaaaccattcctatctggagtctctg
acagacaaatctaaggagctgccgttatactgttccggggggctgcggtttttctgggac
aacaagtttgaccatgccatggtggctttcctggactgtgtgcagcagttcaaagaagag
gttgagaaaggcgagacacgtttttgtcttccttacaggatggatgtggagaaaggcaag
attgaagacacaggaggcagcggcggctcctattccatcaaaacccagtttaactctgag
gaacagtggacaaaagctctcaagttcatgctgacaaatcttaagtggggtcttgcttgg
gtatcctcacagttttataacaaatga

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