Corvus cornix (hooded crow): 104693503
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Entry
104693503 CDS
T03546
Symbol
GCLC
Name
(RefSeq) glutamate--cysteine ligase catalytic subunit isoform X1
KO
K11204
glutamate--cysteine ligase catalytic subunit [EC:
6.3.2.2
]
Organism
ccw
Corvus cornix (hooded crow)
Pathway
ccw00270
Cysteine and methionine metabolism
ccw00480
Glutathione metabolism
ccw01100
Metabolic pathways
ccw01240
Biosynthesis of cofactors
ccw04216
Ferroptosis
Module
ccw_M00118
Glutathione biosynthesis, glutamate => glutathione
Brite
KEGG Orthology (KO) [BR:
ccw00001
]
09100 Metabolism
09105 Amino acid metabolism
00270 Cysteine and methionine metabolism
104693503 (GCLC)
09106 Metabolism of other amino acids
00480 Glutathione metabolism
104693503 (GCLC)
09140 Cellular Processes
09143 Cell growth and death
04216 Ferroptosis
104693503 (GCLC)
Enzymes [BR:
ccw01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.2 glutamate---cysteine ligase
104693503 (GCLC)
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Motif
Pfam:
GCS
GCS2
SANT_DAMP1_like
Motif
Other DBs
NCBI-GeneID:
104693503
NCBI-ProteinID:
XP_039425290
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Position
3:91210910..91248046
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AA seq
647 aa
AA seq
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MGLLSQGSPLSWEETRRYAEHVRRHGILQFLHIYRALRDRHKDVLKWGDEVEYMLVKFDH
ENKKVRLVLCGEEVLQTLQDKGEKVNPNHPTLWRPEYGSYMIEGTPGQPYGGTMSEFNTV
QDNMRKRRQEAASVLKENEAVCTVTSFPRLGCPGFTLPEYKPTPVEGGASKSLFFPDEAI
NKHPRFSTLTRNIRHRRGEKVVINVPIFKDKNTPSPFIETFPNDDGEAAKAAKPDYIYMD
AMGFGMGNCCLQVTFQACSISEARYLYDQLATICPIVMALSAASPFYRGYVSDIDCRWGV
ISASVDDRTREERGLEPLKNNHYRISKSRYDSIDSYLSECGEKYNDIDLTIDKDIYERLI
KEGIDHLLAQHIAHLFIRDPLTLFEEKIHLDDANESDHFEVTFDLEEFNKHNIQSTNWQT
MRFKPPPPNSDIGWRVEFRPMEVQLTDFENSAYVVFVVLLTRVILSYKLDFLIPLSKVDE
NMKVAQKRDAVRQGMFYFRKDICKGGNAVVDGCGSAQNGTGTDTEEYTLMSIDTIINGKE
GVFPGLIPILNSYLENMEVDVDTRCTILNYLKLIKKRASGELMTVARWMREFIAQHPDYK
QDSVITDEINYSLMWKCNQIAQGQAECPELLGVGFNKKQSGNKTDSL
NT seq
1944 nt
NT seq
+upstream
nt +downstream
nt
atggggctgctgtcgcagggctcgccgctgagctgggaggagacgcggcggtacgcggag
cacgtgcggcggcacggcatcctccagttcctccacatctaccgcgccctgcgcgaccgc
cacaaggacgtgctcaagtggggcgacgaggtggaatatatgttggtaaaatttgaccat
gaaaataagaaagtgcgcttggtactctgtggtgaagaagttcttcaaacactgcaagac
aagggggagaaggtaaaccccaatcacccaacactctggagaccagaatatggaagttac
atgattgaagggacacctggacagccatatgggggaaccatgtctgaattcaacactgtg
caagacaacatgaggaaaagacggcaagaggctgcttctgtacttaaagaaaatgaggct
gtttgcacagtgacatcatttccaaggttagggtgtcctgggtttacactgccggaatat
aagccaacaccagtagaaggaggagcttcaaaatccctcttttttccagatgaagccatc
aataaacatcctagatttagtacgctgaccagaaacattcgacaccgaagaggagagaag
gttgtgataaatgtaccaatatttaaagataagaacacgccatcaccttttattgaaaca
tttcctaatgatgatggagaagcagcaaaggcagctaagccagactacatatatatggat
gctatgggttttggaatgggaaactgttgtctccaggtaacatttcaggcttgcagcatt
tctgaagcaaggtatctttatgatcagctagctacaatttgtcccattgtgatggcgttg
agtgctgcatctccattctacagaggctacgtgtctgacattgactgtcgctggggagtg
atctctgcttccgtggatgatcgaacgcgggaggagagagggctagagccactgaagaac
aaccattatagaatcagtaaatccagatatgattccatagacagttatctatctgaatgt
ggtgagaaatacaatgacattgatttgacaatagacaaagatatctacgagcgcctaata
aaggaaggtattgaccatcttttggcacagcatattgcacacttgttcattcgagaccca
ttgactttgtttgaggagaaaatacatctagatgatgcaaatgaatccgaccattttgag
gttacgtttgatttagaggaatttaataaacataatattcagtctacaaactggcagaca
atgaggtttaagccaccacctccaaattcagatattggatggagagtggaattcagacct
atggaggtccagttaacagactttgaaaactctgcatatgttgtgtttgtggtattgcta
accagagtgattctgtcatataaactggattttctcattcctttgtccaaggtggatgaa
aacatgaaggtggcccagaaaagagatgctgtccgacagggaatgttttacttcagaaaa
gatatatgcaaaggtggaaatgctgttgtggatggatgtggctctgcacagaatgggaca
ggcaccgacacagaagagtacaccttaatgagcattgatacaattatcaatgggaaggaa
ggagtctttcctggtttgatcccaattttgaattcctatcttgaaaacatggaagtggat
gtggacacaagatgcaccatcctaaactatctgaagctaataaaaaagagagcctctgga
gaattaatgacagttgctcgatggatgagggaatttatcgcacagcatccagactacaag
caagacagtgtgataactgatgaaattaattacagccttatgtggaaatgcaaccaaatt
gcacaaggccaggcagagtgtcctgaactgttgggggtaggattcaataagaaacaaagt
ggaaacaaaactgattctttgtaa
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