Corallococcus coralloides: COCOR_00009
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Entry
COCOR_00009 CDS
T01780
Symbol
thrA
Name
(GenBank) aspartate kinase/homoserine dehydrogenase
KO
K12524
bifunctional aspartokinase / homoserine dehydrogenase 1 [EC:
2.7.2.4
1.1.1.3
]
Organism
ccx
Corallococcus coralloides
Pathway
ccx00260
Glycine, serine and threonine metabolism
ccx00261
Monobactam biosynthesis
ccx00270
Cysteine and methionine metabolism
ccx00300
Lysine biosynthesis
ccx01100
Metabolic pathways
ccx01110
Biosynthesis of secondary metabolites
ccx01120
Microbial metabolism in diverse environments
ccx01230
Biosynthesis of amino acids
Module
ccx_M00016
Lysine biosynthesis, succinyl-DAP pathway, aspartate => lysine
ccx_M00018
Threonine biosynthesis, aspartate => homoserine => threonine
Brite
KEGG Orthology (KO) [BR:
ccx00001
]
09100 Metabolism
09105 Amino acid metabolism
00260 Glycine, serine and threonine metabolism
COCOR_00009 (thrA)
00270 Cysteine and methionine metabolism
COCOR_00009 (thrA)
00300 Lysine biosynthesis
COCOR_00009 (thrA)
09110 Biosynthesis of other secondary metabolites
00261 Monobactam biosynthesis
COCOR_00009 (thrA)
Enzymes [BR:
ccx01000
]
1. Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.1.1 With NAD+ or NADP+ as acceptor
1.1.1.3 homoserine dehydrogenase
COCOR_00009 (thrA)
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.2 Phosphotransferases with a carboxy group as acceptor
2.7.2.4 aspartate kinase
COCOR_00009 (thrA)
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GFIT
Motif
Pfam:
Homoserine_dh
AA_kinase
ACT_9
NAD_binding_3
ACT_7
ACT
Motif
Other DBs
NCBI-ProteinID:
AFE10482
UniProt:
H8MRX3
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Position
8356..10812
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AA seq
818 aa
AA seq
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MRVMKFGGTSVGDAERMRGVVALVEEARKAERVMVVASAVSGITNLLVEAAKVAQEGESV
QEACARFDDTHSAIAKALSVDLKPAQTRPLAEGLVALGVELRGLLQGVGLLRECSPSVLA
HLSGLGERASCLLLAALLEARGLSPVSLDPRQVLVCSGDPLQATPRVEEIRARFATLREG
GPGLMLMPGFFGGDARGKTMSLGRGGSDYSAALAASALDARLLEIWTDVDGIFSADPRLV
PEAFTLEEVSFEEAMELAYFGAKVLHPKTIAPARERGIPVRVCNSFRPEHPGTRVTATAP
ASRHPVRGLSFLPDIALINIAGAGLKGVPGTAARVFEAMALASISVVLITQGSSESSISF
CVGETEATRAVLALEDEFEVEREAGKVDPIEHQPGLAVLSIVGDGMRHRVGVAGTFFSAL
ADVDCSIAAIAQGSSERSISAVISREDGPRAMAHVHRKAFGTTEVVELLVAGVGTVGGEL
LRQIHQQAPKLRAHGLDLRVCAIANSRHSLVAPEGVALDGWKARLEASESGFTLDTFQAW
AKARRPGRPIFVDCTSSEDVALGYPALMASGLHVVTANKKANAGRQEHWRALRETAVRHQ
RKFLYETNVGAGLPVIDTLKNMLRTGDTVHRVEGILSGSLSFILGLTEAGVPLSKAVGTA
MEKGFTEPDPRDDLEGTDVARKVLILARELGRSLELEEVALASLLPEEFDAKGPLPEFLA
RLPQADEIFQRRVDAHRKEGKVLRYVGSVGPEGVRVGLVPVPLEHPLAAVKGGENALSFL
SERYSPTPLVIRGYGAGAAVTAAGVLADVLRLVEGPLP
NT seq
2457 nt
NT seq
+upstream
nt +downstream
nt
atgcgcgtgatgaaattcggtggcaccagtgtcggagatgcggagcggatgcgcggcgtg
gtggcgctggtggaggaggcgcgcaaggccgagcgggtgatggtggtggcctccgcggtg
tcgggcatcacgaatctgttggtggaggctgcgaaggtggcgcaggagggcgagtccgtg
caggaggcctgcgcccggttcgacgacacgcactccgccatcgcgaaggcgctgagcgtg
gacctgaagcccgcgcagacgcgtccgctggcggaggggttggtggcgcttggcgtcgag
ctgcgcgggctgttgcagggcgtggggctcctgcgggagtgctcgccgtcggtgctggcg
cacctgtcggggctgggggagcgggcgtcgtgtttgctgctcgcggcgctgctggaggca
cgggggctttcgcccgtgagcctggacccgaggcaggtgctggtgtgttcaggagacccg
ctacaggcgacgccccgggtggaggagatccgcgcgcggttcgcgacgctgcgtgagggc
gggccggggctgatgttgatgccgggcttcttcggtggggatgcgcgcggcaagacgatg
tcgctggggcggggagggtcggactactcggcggcgctggcggcgtcggcgctggatgcg
cggctgttggagatctggacggacgtggacggcatcttcagcgcggatccgcggctggtg
ccggaggcgttcacgctggaggaggtgagcttcgaggaggcgatggagctggcctacttc
ggggcgaaggtgctgcatccgaagacgattgctcccgcgagggagcggggcatcccggtg
cgggtgtgcaacagcttccggcccgagcatccgggcacgcgggtgacggccacggcgccg
gcttcacggcacccggtgcgggggttgtcgttcctgccggacatcgcgctcatcaacatc
gcgggcgcggggttgaagggtgtgccgggcacggccgcgcgcgtcttcgaggcgatggcg
ctggcgtccatctccgtggtgctgatcacccagggctccagcgagtcctccatcagcttc
tgcgtgggggagacggaggccacgcgggcggtgctggcgctggaggacgagttcgaggtg
gagcgcgaggcggggaaggtagaccccatcgagcaccagccggggctcgcggtgttgagc
atcgtgggagacgggatgcggcaccgggtgggcgtggcggggacgttcttcagcgcgctg
gcggacgtggattgcagcatcgcggccatcgcgcaggggtcgagcgagcggagcatctcc
gcggtgatttctcgcgaggacgggccgcgagcgatggcccacgtgcaccgcaaggccttt
ggcaccacggaggtggtggagctgctggtggcgggcgtgggcacggtgggcggggagctg
ttgcggcagattcatcagcaggcgccgaagctgcgggcacacgggttggatttgcgcgtg
tgtgccattgcgaatagcagacacagcctggtggcgccggagggtgtggcgctggatgga
tggaaggcgcggctggaggcaagcgagtctggtttcacgttggacacgttccaagcgtgg
gcgaaggcgaggcgtccgggccggcccatcttcgtggactgcacgagcagcgaggacgtg
gcgctggggtatccggcgttgatggcgtccgggctgcacgtggtgacggcgaacaagaag
gccaatgcggggcggcaggagcactggagggcgctgcgggagacggcggtgcggcaccag
cggaagttcctctacgagacgaacgtgggggcggggctgccggtcatcgacacgttgaag
aacatgctgcgcacgggagacacggtgcaccgggtggagggcatcctgtcgggttcgctg
tcgttcatcctggggctgacggaggccggggtgccgctgtcgaaggccgtgggcacggcg
atggagaagggcttcacggagccggatccgcgcgacgacctggagggcacggacgtggcg
cgcaaggtgctcatcctcgcgcgcgagctggggcggtcgctggagctggaggaggtggcg
ctggcgtcgctgttgccggaggagttcgacgcgaaggggccgctgccggagttcctggcg
cggctgccgcaggcggatgagatcttccagagacgggtggatgcgcaccggaaggaaggc
aaggtgctgcgctacgtgggcagcgtggggccggagggcgtgcgcgtgggcctggtgccg
gtgccactggagcatccgctggcggcggtgaagggcggcgagaacgcgctgagcttcctg
tcggagcggtacagccccacgccgctggtgattcgaggctacggcgcgggcgcggcggtg
acggcggcgggagtgctcgcggatgtattgcgattggtggaggggccgttgccctga
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