Corallococcus coralloides: COCOR_06423
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Entry
COCOR_06423 CDS
T01780
Symbol
thrA1
Name
(GenBank) aspartate kinase/homoserine dehydrogenase
KO
K12524
bifunctional aspartokinase / homoserine dehydrogenase 1 [EC:
2.7.2.4
1.1.1.3
]
Organism
ccx
Corallococcus coralloides
Pathway
ccx00260
Glycine, serine and threonine metabolism
ccx00261
Monobactam biosynthesis
ccx00270
Cysteine and methionine metabolism
ccx00300
Lysine biosynthesis
ccx01100
Metabolic pathways
ccx01110
Biosynthesis of secondary metabolites
ccx01120
Microbial metabolism in diverse environments
ccx01230
Biosynthesis of amino acids
Module
ccx_M00016
Lysine biosynthesis, succinyl-DAP pathway, aspartate => lysine
ccx_M00018
Threonine biosynthesis, aspartate => homoserine => threonine
Brite
KEGG Orthology (KO) [BR:
ccx00001
]
09100 Metabolism
09105 Amino acid metabolism
00260 Glycine, serine and threonine metabolism
COCOR_06423 (thrA1)
00270 Cysteine and methionine metabolism
COCOR_06423 (thrA1)
00300 Lysine biosynthesis
COCOR_06423 (thrA1)
09110 Biosynthesis of other secondary metabolites
00261 Monobactam biosynthesis
COCOR_06423 (thrA1)
Enzymes [BR:
ccx01000
]
1. Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.1.1 With NAD+ or NADP+ as acceptor
1.1.1.3 homoserine dehydrogenase
COCOR_06423 (thrA1)
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.2 Phosphotransferases with a carboxy group as acceptor
2.7.2.4 aspartate kinase
COCOR_06423 (thrA1)
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GFIT
Motif
Pfam:
Homoserine_dh
AA_kinase
ACT_9
NAD_binding_3
ACT
Motif
Other DBs
NCBI-ProteinID:
AFE10483
UniProt:
H8MSX6
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All DBs
Position
8091078..8093591
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AA seq
837 aa
AA seq
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MTAPVSITRYAPFLLDTAQGLASVATHLSRRDAGSTRAAIVSSPPWLAAGLESALSTALK
GNSTLARQELDGLLARGLLMLEEAERRLGAPPGSTSVEADGSRTLASLLEPARRALDGAS
LVRERRPALEDVVRGTGERLTAALLAKLLGARGVPSLEVDAADWTVTEGEPGQARVNREH
TRARVATLRPSWEGRLTLHAGGRGTAVDGRSTTLGVEGADETAAVLSVLLGTPLTLWTDV
PGVMTADPLHVADARPVPHLSYTEALELVYLGLPTLHPRALSTLRDADIPLRVRHLQQPD
EPGTLIDVRGAGNGTVPTCVVSLEDLALLGLEGGTEEAARPVGPRALQALEAAGIDAWMA
AQSSPGRSVAVVLRRAHAARAEQVLRRELAPELERGALQPPQVRAPVTQVALVAEAMGQG
ANVAGRLFQPLGALGVNVRAIAQTASARSISFIVDGAETALTVRTVHAAFHFAHEEVSLL
VLGHGVVGSQLLEQLRMLQETLAQGHGIQLNLVGLADSRRVLFSPEGIPLKQWRERIQSV
PEGASPPVVRALLEPLRRLPVPVLVDCTAAEGMQELYLEAFRSGIHVVAANKKPLTQPLE
VWERLRSTAHLNHRAYHYETTVGAGLPVIQTLKDLVRTGDRVHGVEGSFSGTLGYLSQQL
MDGVPLSKAVRTAREKGFTEPHPREDLAGTDAARKALILAREQGLDLSMEDVEVEPFVPR
EYLEEADVERFLTGLEKLDRTFTSRIEGLRAEGKVLRYLARIDPAAKDGPVLRVGPVAVP
KEHPATRLRGSEAFVAFSTERYADYPLLVQGAGAGGPVTAAGVLADILKIAQNLRGR
NT seq
2514 nt
NT seq
+upstream
nt +downstream
nt
atgaccgcccctgtgagcatcacccgttacgctccgttcctgctcgacacggcccaggga
ctcgcgtccgtggccacgcacctgtcgcgccgcgacgcgggcagcacgcgcgccgccatc
gtgtcctcaccgccctggctcgccgcggggctggagtccgcgctgtccaccgcgttgaag
ggcaactccacgctggcccggcaggagctggatggcctgctcgcgcgaggcctgttgatg
ctggaggaggccgagcgccggctgggcgcgcccccgggctccacgtcggtggaggcggac
ggctcgcgcacgttggcatcgctgctggagcccgcgcgccgcgcgctggatggcgcgagc
ctggtgcgcgagcggcggcccgcgctggaggacgtggtgcgcggcaccggcgagcggttg
acggcggcgctgctggcgaagctgctgggtgcgcgcggcgtgccgtcgctggaggtggac
gcggcggactggacggtgacggagggtgagcccggacaggcgcgcgtgaaccgcgagcac
acccgcgcccgggtggccacgctgcggccttcgtgggagggacggctgacgttgcacgcg
ggtggccgggggacggcggtggatggccgctccacgacgctgggcgtggagggcgcggac
gagacggcggcggtgctgtccgtgctgctgggcacgccgctgacgctgtggacggacgtg
cctggggtgatgacggcggatccgctgcacgtcgcggatgcgcggccggtgccacacctg
agctacacggaggcgctggagctggtgtacctgggcctgcccacgctgcacccgcgcgcg
ctgtccacgctgcgcgacgcggacatcccgctgcgcgtgcgccacctgcaacagcctgac
gagcccggcacgctcatcgacgtgcgcggcgcgggcaacggcaccgtgcccacgtgcgtg
gtgtccctggaggacctggcgctgctgggcctggagggcggcacggaggaggcggcgcgt
ccggtggggcctcgcgcgttgcaggcgctggaggccgcgggcatcgacgcgtggatggcg
gcgcagtcgtcaccggggcgctcggtggcggtggtgctgcgccgggcgcacgcggcccgc
gcggagcaggtgctgcggcgggagctggcgccagagctggagcgcggcgcgttgcagccg
ccacaggtgcgcgcgccggtgacgcaggtggcgctggtggcggaggccatgggccagggc
gccaacgtggcgggacggctgttccaaccgctgggcgcgctgggcgtcaacgtgcgcgcc
atcgcgcagacggcgagcgctcgctccatctcgttcatcgtggatggggcggagacggcg
ctgacggtgcgcacggtgcacgcggccttccacttcgcgcatgaagaggtgagcctgctg
gtgctgggccatggcgtggtgggcagccagttgctggagcagctgcgcatgttgcaggag
acgctggcgcaggggcacggcatccagctcaatctggtggggctcgcggacagccggcgg
gtgctcttctcgccggagggcatcccgctgaagcagtggcgcgagcgcatccagtccgtg
cccgagggcgcgtcaccgcccgtggtgcgcgcgctgctggagccgctgcgccggctgccc
gtgccggtgctggtggactgcactgcggcggagggcatgcaggagctgtacctggaagcg
ttccgcagcggcatccacgtggtggcggcgaacaagaagccgctgacccagccactcgag
gtctgggagcggctgcggagcacggcgcacctgaaccaccgcgcgtaccactacgagacg
acggtgggcgcgggcctgccggtcatccagacgctgaaggacctggtgcgcacgggcgac
cgggtgcacggcgtggagggttcgttctccgggacgctcggctacttgagccagcagttg
atggacggagtgccgctgtcgaaggcggtgcgcaccgcgcgcgagaagggcttcacggag
ccgcaccctcgcgaggacctggcgggcacggacgccgcgcgcaaggcgctcatcctcgcg
cgtgagcaaggcctggacctgtcgatggaggacgtggaggtggagccgttcgtgccgcgc
gagtacctggaggaggcggacgtggagcgcttcctcacggggctggagaagctggaccgg
acgttcacctcgcgcatcgagggactgcgcgcggagggcaaggtgctgcgctacctggcg
cgcatcgacccggcggcgaaggacgggccggtgctgcgggtggggccggtggcggtgccg
aaggagcatccggcgacacggctgcgcggctcggaggcgttcgtggccttctccacggag
cgctacgcggactacccgctgctggtccagggcgcgggggcaggcggccctgtcacggcg
gcgggcgtcctcgcggacatcctgaagatcgcccagaacctgcgggggcgctga
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