Corynebacterium diphtheriae BH8: CDBH8_2099
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Entry
CDBH8_2099 CDS
T01698
Symbol
purL
Name
(GenBank) phosphoribosylformylglycinamidine synthase
KO
K01952
phosphoribosylformylglycinamidine synthase [EC:
6.3.5.3
]
Organism
cdb
Corynebacterium diphtheriae BH8
Pathway
cdb00230
Purine metabolism
cdb01100
Metabolic pathways
cdb01110
Biosynthesis of secondary metabolites
Module
cdb_M00048
De novo purine biosynthesis, PRPP + glutamine => IMP
Brite
KEGG Orthology (KO) [BR:
cdb00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
CDBH8_2099 (purL)
Enzymes [BR:
cdb01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.5 Carbon-nitrogen ligases with glutamine as amido-N-donor
6.3.5.3 phosphoribosylformylglycinamidine synthase
CDBH8_2099 (purL)
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Gene cluster
GFIT
Motif
Pfam:
GATase_5
AIRS_C
FGAR-AT_linker
AIRS
DJ-1_PfpI
GATase_3
Motif
Other DBs
NCBI-ProteinID:
AEX49614
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All DBs
Position
2186825..2190541
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AA seq
1238 aa
AA seq
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MDARLAIRRSPNFRDEERALLRSLNNLEGAPLTDVQIINVYDVFDATEADITALTNSIVS
DPKVDTVLTTAELDTIVEQAPAHLAVEPLPGQYDQRADAAEQALRLLNPHTNARVTSGEL
YIFSDLTEEAFANIRDYLINPVEAGEKNLDVLRAPSMGDIAPLKQYPDFLELDEAGLSAL
LASEGMAMSLADLKLIQEYFRTEGRTPTEVELAALDTYWSDHCRHTTFNTELTEITNSSS
RYGAQLDRALKRYDELREANGRAHKPRTLMDLGTIMGRELRRNGTMTDQEVSEEINACSV
YVDVDTPEGDKPWLLMFKNETHNHPTEIEPFGGASTCLGGAIRDPLSGRSWVYQAMRISG
AGDINTPRTETIDGKLPQADISARATHGYSSYGNQIGLATTSVRELIHPGYVAKRMELGA
VVAAAPQENVKRLEPQPGDVVIILGGRTGRDGVGGATGSSKAHDEESLARSGAEVQKGNP
VNERKIQRLFRRPEIAQMIVRCNDFGAGGVSVAVGELTDSIDIHLDRVPLKYAGLNAREI
AISESQERMAVVVRPEDAAAFIEAAATENIEAVELATVTDSGRLRMFLGEDVVLDLSREF
LETNGAARSQSVEMRDAGDVEKPAQPATVLESLTRHGSQEGMVEQFDATVGRSTVLMPYG
GRTQKTDELASVQTFPVPGGSHTASVMTYGFSPELADVSPYLMGSYSVVEALSRLVATGA
NARGAWLSVQEYFQRLDQKPELWGEVTQALLGLLEAQDAFEVAAIGGKDSMSGTYGDDLH
VPATLVTFAVATMDARRTLSAAIPSGEFDVYHLAHTPLETGEANYEQLRSNFDAFHELAA
TGTLSAASPIIPSGLGATIVNMLLGNELGFQGTATTNAALGGLVFAVPAGTAVELADAQL
IGHTNPSGEIAFGEETFTIAQALDTLERDYREVYPLNVTTADVEALPEFATALRMADSDS
EEANASAGDKAVHVLLPVFPGTNSEYDMAEAFEAAGATTEFHIIRNLNSEMLAADTEAFI
TKLQSANILAFSGGFSLGDEPDGSAKFMAAFLRSDAVATAVKDFVAGDGLVLGICNGFQA
LVKSGFLPYGDPAKMSAESPTLAHNRQLRHVSRIATTRVSSVASPWLSTFTPGQQHLMPV
SHGEGRFVVSETEAQALFSAGQIAFQYVDADGTPTMEAPANPNGSNYAIEGIISPDGRIL
GKMGHPERFRDGLMRNIPGMAVQDIFANAVNYCRKSQR
NT seq
3717 nt
NT seq
+upstream
nt +downstream
nt
atggacgcgcgtcttgccattcgccgctcacccaacttccgcgacgaggagcgcgcgcta
ctgcgttccctcaacaacctagaaggcgcccccctcaccgacgtccagatcatcaatgtc
tacgacgtcttcgacgccaccgaagcagacatcaccgccctaacaaactccatagtcagc
gaccccaaggtggacaccgtactcactacagctgagctcgacaccatcgtcgaacaagca
ccagctcatctcgcggtcgaaccactacctggccaatacgaccagcgcgccgacgcagcc
gaacaagcactacgactgctcaacccccacaccaacgcacgtgtaacctccggcgagctt
tatatcttcagcgacctaaccgaagaggcattcgccaacatccgcgactacctgatcaac
cccgtcgaagcaggcgagaaaaacctcgacgtactgcgcgcaccatccatgggcgacatc
gccccactcaagcaatacccagatttccttgagctcgacgaagctggcttgagcgcattg
ctggccagcgaaggcatggccatgagcttggcggacctgaagcttattcaggaatacttc
cgcaccgaaggccgcacccccaccgaggtggaactggcagcactggacacctactggtcc
gatcactgccgccacaccacctttaacaccgagctgacggagatcaccaactccagcagt
cgttacggtgcacagctcgaccgcgcactgaagcgttacgacgaactccgcgaagccaac
ggtcgcgcccataagccacgcaccctcatggacttgggcaccatcatgggccgtgagctg
cgtcgcaacggaaccatgaccgatcaagaagtcagcgaagaaatcaacgcctgctccgta
tacgttgacgtggacaccccagaaggtgacaagccttggctgctgatgttcaaaaacgaa
acccacaaccaccccaccgaaatcgaaccattcggtggcgcatccacctgcctcggtggc
gcaatccgcgacccactatccggtcgctcttgggtttaccaagcaatgcgcatctccggc
gccggtgacatcaacaccccacgcaccgaaacgatcgacggcaaactgccccaggcagac
atcagtgcccgcgcaacccacggctactccagctacggcaaccagatcggtctggcaacc
accagcgtccgcgaactgattcacccaggttacgtcgccaagcgcatggaactcggcgcc
gttgtggcagccgcaccacaagaaaacgtcaagcgcctagagccacaaccaggcgacgta
gtgatcatcctcggtggccgcaccggacgcgacggcgtgggcggagccaccggctcctcc
aaggcacacgacgaagaatccttggcacgctcgggtgcagaagtccaaaaaggcaacccc
gtcaacgaacgcaagatccaacgcctgttccgccgaccagaaatcgcccaaatgatcgtg
cgctgcaatgacttcggcgcaggtggcgtgtccgtcgcagtcggcgaactcaccgacagc
atcgacatccacctcgatcgcgtaccactgaaatacgccggcctcaatgcccgcgaaatc
gccatctccgagtcccaggaacgcatggcagtcgtcgtgcgcccagaagacgcagccgcc
ttcattgaagcagccgcaaccgaaaacatcgaggctgtagagctcgccaccgtcaccgac
agcggacgcctgcgcatgttcctcggcgaagacgtagtcctcgacctctcccgcgaattc
ctcgaaaccaacggcgcagcacgctcccagagcgtagaaatgcgcgatgcaggagacgtc
gaaaagcctgctcagccggcaaccgtcctcgaatccttgacccgccacggctcccaagaa
ggcatggtcgaacaattcgacgccaccgtcggacgctccaccgtactcatgccttacggc
ggccgcacccaaaaaaccgacgaactcgcatccgtacaaaccttcccagtaccaggcgga
tcccacaccgcatcggtcatgacctacggattcagcccagagcttgccgacgtctccccc
tacctcatgggctcctactccgtcgtcgaagcactcagccgactcgtcgccaccggtgcc
aacgcacgcggcgcatggctgtccgtccaagaatatttccaacgcctcgaccaaaaaccc
gaactctggggcgaagtaacccaagcactcctgggccttcttgaagcacaagacgccttc
gaagtagctgccatcggcggcaaagactccatgagcggcacctacggcgatgacctgcac
gttcccgcaacgctggtcaccttcgcagtcgcaaccatggacgcacgacgcaccctcagc
gccgccatcccaagcggcgaattcgacgtctaccacctcgcccacaccccgctggaaacc
ggcgaagccaactacgagcaactccgctccaacttcgacgccttccatgagctcgccgcc
accggcaccctctcggcagcttcccccatcatcccaagtgggctcggcgccaccatcgtg
aacatgctgctcggcaacgaactcggattccagggcaccgccaccaccaacgcagccctc
ggtggcctcgtattcgcggtcccagccggcaccgcagtcgagcttgccgacgcccaactc
atcggtcacaccaacccatccggcgagatcgccttcggcgaagaaaccttcaccatcgcc
caagcactcgacaccctagagcgcgactaccgcgaggtctaccccctcaacgtaaccacc
gcagacgtagaggccctcccagagtttgcgaccgccctacgcatggcagactcggattct
gaagaagccaacgcctccgccggtgacaaagccgtacacgtgttgcttccagtattccca
ggtactaactccgaatacgacatggcagaggccttcgaagcagcaggtgccaccactgaa
ttccacatcatccgaaacctcaactcggagatgctggctgctgacacagaagcattcatc
accaagctgcaatccgccaacatcctggcattctccggcggattctccctcggcgacgaa
ccagacggctccgcaaaattcatggcagccttcctacgctccgacgccgtagccacagcg
gtcaaggacttcgtcgccggcgacggcctcgtcctcggaatctgcaacggcttccaagca
ctggtcaagagcggattcctgccatacggcgaccccgccaagatgagcgcagaatcccca
acgttggcacacaaccgccaactgcgacacgtctcacgcatcgccaccactcgcgtcagc
tccgtagcctccccatggctgagcaccttcaccccaggccagcagcacctcatgccagta
tcccacggcgaaggccgcttcgtggtatccgaaacggaagcccaagcactgtttagcgca
ggtcagatagcattccagtatgtggatgccgacggcacccccaccatggaagcacctgcg
aaccccaacggatccaactatgccatcgagggcatcatctccccagatggtcgcatcctt
ggcaagatgggtcacccagagcgcttccgcgacggcctcatgcgcaacattcctggtatg
gcggtccaagacatcttcgctaacgcggtgaactactgccgtaagagtcaacgctag
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