Corynebacterium diphtheriae HC02: CDHC02_2025
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Entry
CDHC02_2025 CDS
T01694
Symbol
purL
Name
(GenBank) phosphoribosylformylglycinamidine synthase
KO
K01952
phosphoribosylformylglycinamidine synthase [EC:
6.3.5.3
]
Organism
cde
Corynebacterium diphtheriae HC02
Pathway
cde00230
Purine metabolism
cde01100
Metabolic pathways
cde01110
Biosynthesis of secondary metabolites
Module
cde_M00048
De novo purine biosynthesis, PRPP + glutamine => IMP
Brite
KEGG Orthology (KO) [BR:
cde00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
CDHC02_2025 (purL)
Enzymes [BR:
cde01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.5 Carbon-nitrogen ligases with glutamine as amido-N-donor
6.3.5.3 phosphoribosylformylglycinamidine synthase
CDHC02_2025 (purL)
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Ortholog
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Gene cluster
GFIT
Motif
Pfam:
GATase_5
AIRS_C
FGAR-AT_linker
AIRS
DJ-1_PfpI
GATase_3
Motif
Other DBs
NCBI-ProteinID:
AEX77512
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All DBs
Position
2190880..2194596
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AA seq
1238 aa
AA seq
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MDARLAIRRSPNFRDEERALLRSLNNLEGAPLTDVQIINIYDVFDATEADITALTNSVVS
DPKVDTVLTTAELDTIVEQAPAHLAVEPLPGQYDQRADAAEQALRLLNPHTNARVTSGEL
YIFSDLTEEAFANIRDYLINPVEAGEKNLDVLRAPSMGNIAPLKQYPDFLELDDAGLSAL
LASEGMAMSLADLKLIQEYFRTEGRAPTEVELAALDTYWSDHCRHTTFNTELREITNSSS
RYGAQLDRALKRYDELREANGRAHKPRTLMDLGTIMGRELRRNGTMTDQEISEEINACSV
YVDVDTPEGDKPWLLMFKNETHNHPTEIEPFGGASTCLGGAIRDPLSGRSWVYQAMRISG
AGDINTPRTETIDGKLPQADISARATHGYSSYGNQIGLATTSVRELIHPGYVAKHMELGA
VVAAAPQENVKRLEPQPGDVVIILGGRTGRDGVGGATGSSKAHDEESLARSGAEVQKGNP
VNERKIQRLFRRPEIAQMIVRCNDFGAGGVSVAVGELTDSIDIHLDRVPLKYAGLNAREI
AISESQERMAVVVRPEDAAAFIEAAATENIEAVELATVTDSGRLRMFLGKDLVLDLSREF
LETNGAARSQSVEMRDAGDVEKPAQPATILESLTRHGSQEGMVEQFDATVGRSTVLMPYG
GRTQKTDELASVQTFPVPGGSHTASVMTYGFSPELADVSPYLMGSYSVVEALSRLVATGA
NARGAWLSVQEYFQRLDQKPELWGEVTQALLGLLEAQDAFEVAAIGGKDSMSGTYGDDLH
VPATLVTFAVATMDARRTLSAAIPSGEFDVYHLAHTPLETGEANYEQLRANFDAFHELAA
TGTLSAASPIIPGGLGATIVNMLLGNELGFQGTATTNAALGGLVFAVPAGTAVELADAQL
IGHTNPSGEIAFGEETFTIAQALDTLERDYREVYPLNVTTADVDALPEFATALPTADSDS
VKANASAGDKAVHVLLPVFPGTNSEYDMAEAFEAAGATTEFHIIRNLNSEMLAADTEAFI
TKLQSANILAFSGGFSLGDEPDGSAKFMAAFLRSDAVATAVKDFVAGDGLVLGICNGFQA
LVKSGFLPYGDPAKMSAESPTLAHNRQLRHVSRIATTRVSSVASPWLSTFTPGQQHLMPV
SHGEGRFVVSEKEAQALFSAGQVAFQYVDAEGTPTMEAPANPNGSNYAIEGIISPDGRIL
GKMGHPERFRDGLMRNIPGMEIQDIFANAVNYCRKSQR
NT seq
3717 nt
NT seq
+upstream
nt +downstream
nt
atggacgcgcgtcttgccattcgccgctcacccaacttccgcgacgaggagcgcgcgcta
ctgcgttccctcaacaacctagaaggcgcccccctcaccgacgtccagatcatcaatatc
tacgacgtcttcgacgccaccgaagcagacatcaccgccctaacaaactccgtagtcagc
gaccccaaggtggacaccgtacttactacagctgagctcgacaccatcgtcgaacaagca
ccagctcatctcgcggtcgaaccactacctggccaatacgaccagcgcgccgacgcagcc
gaacaagcactacgactgctcaacccccacaccaacgcacgtgtaacctccggggagctt
tatatcttcagcgacctaaccgaagaggcattcgccaacatccgcgactacctgatcaac
cccgtcgaagcaggcgagaaaaacctcgatgtactgcgcgcaccatccatgggtaacatc
gccccactcaagcaatacccagatttccttgagctcgacgacgctggcttgagcgcattg
ctggccagcgaaggcatggccatgagcttggcggacctgaagcttattcaagaatacttc
cgcaccgaaggccgcgcccccaccgaggtggaactggcagcactggacacctactggtcc
gatcactgccgccacaccacctttaacaccgagctgagggagatcaccaactccagcagt
cgttacggtgcacagctcgaccgcgcactgaagcgttacgacgaactccgcgaagccaac
ggtcgcgcccataagccacgcaccctcatggacttgggcaccatcatgggccgtgagctg
cgtcgcaacggaaccatgaccgatcaagagatcagcgaagaaatcaacgcctgctccgta
tacgttgacgtggacaccccagaaggtgacaagccttggctgctgatgttcaaaaacgaa
acccacaaccaccccaccgaaatcgaaccattcggtggcgcatccacctgcctcggtggc
gcaatccgcgacccactatccggtcgctcctgggtttaccaagcaatgcgcatctccggc
gccggtgacatcaacaccccacgcaccgaaacgatcgacggcaaactcccgcaggcagac
atcagtgcccgcgcaacccacggctactccagctacggcaaccagatcggtctggcaacc
accagcgtccgcgaactgattcacccaggttacgtcgccaagcacatggaactcggcgcc
gttgtggcagccgcaccacaagaaaacgtcaagcgcctagagccacaaccaggcgacgta
gtgatcatcctcggtggccgcaccggacgcgacggcgtgggcggagccaccggctcctcc
aaagcacacgacgaagaatccttggcacgctcgggtgcagaagtccaaaagggcaacccc
gtcaacgaacgcaagatccaacgcctgttccgccgaccagaaatcgcccaaatgatcgtg
cgctgcaatgacttcggcgcaggtggcgtgtccgtcgcagtcggcgaactcaccgacagc
atcgacatccacctcgatcgcgtaccactgaaatacgccggcctcaacgcccgcgaaatc
gccatctccgagtcccaggaacgcatggcagtcgtcgtgcgcccagaagacgcagccgcc
ttcattgaagcagccgcaaccgaaaacatcgaggcagtagagctcgccaccgtcaccgac
agcggacgcctacgcatgttcctcggcaaggacctagtcctcgacctctcccgcgaattc
ctcgaaaccaacggcgcagcacgctcccagagcgtagaaatgcgcgatgcaggagacgtc
gaaaagcctgctcagccagcaaccatcctcgaatccttgacccgccacggctcccaagaa
ggcatggtcgaacaattcgacgccaccgtcggacgctccaccgtactcatgccatacggc
ggccgcacccaaaaaaccgacgaactcgcatccgtacaaaccttcccagtaccaggcgga
tcccacaccgcatcggtcatgacctacggattcagcccagagcttgccgacgtctccccc
tacctcatgggctcctactccgtcgtcgaagcactcagccgactcgtcgccaccggtgcc
aacgcacgcggcgcatggctgtccgtccaagaatatttccagcgcctcgaccaaaaaccc
gaactctggggcgaagtaacccaggcactcctgggccttcttgaagcacaagacgccttc
gaagtagctgccatcggcggcaaggactccatgagcggcacctacggcgatgacctgcac
gttccagcaacgctggtcaccttcgcagtcgcaaccatggacgcacgacgcaccctcagc
gccgccatcccaagcggcgaattcgacgtctatcatctcgcccacaccccgctggaaacc
ggcgaagccaactacgagcaactccgcgccaacttcgacgccttccatgagctcgccgcc
accggcaccctctcggcagcctcccccatcatcccaggagggctcggcgccaccatcgtg
aacatgctgctcggcaacgaactcggattccagggcaccgccaccaccaacgcagccctc
ggtggcctcgtattcgcggtcccagccggcaccgcagtcgagcttgccgacgcccaactc
atcggtcacaccaacccatccggcgagatcgccttcggcgaagaaactttcaccatcgcc
caagcactcgacaccttggagcgcgactaccgcgaggtctaccccctcaacgtaaccacc
gcagacgtagacgctctcccagagtttgcaaccgccctacccacggcggactcggattct
gtcaaagccaacgcctccgccggtgacaaagccgtacacgtgttgcttccagtattccca
ggtactaactccgaatacgacatggccgaggccttcgaagcagcaggtgccaccaccgaa
ttccacatcatccgaaacctcaactcggagatgctggctgctgacacagaagcattcatc
accaagctgcaatccgccaacatcctggcattctccggcggattctccctcggcgacgaa
ccagacggctccgcaaaattcatggcagccttcctacgctccgacgccgtagccacagcg
gtcaaggacttcgtcgccggcgacggcctcgtcctcggaatctgcaacggcttccaagca
ctggtcaagagcggattcctgccatacggcgaccccgccaagatgagcgcagaatcccca
acgttggcacacaaccgccaactgcgacacgtctcacgcatcgccaccactcgcgtcagc
tccgtagcctccccatggctgagcaccttcaccccaggccagcagcacctcatgccagta
tcccacggcgaaggccgcttcgtagtatccgaaaaggaagcccaagcactgtttagcgca
ggtcaagtagcattccagtatgtggatgccgagggcacccccaccatggaagcacctgcg
aaccccaacggatccaactacgccatcgagggcatcatctccccagatggtcgtattctt
ggcaagatgggacaccccgagcgcttccgcgacggcctcatgcgcaacattcctggtatg
gagatccaagacatcttcgctaacgcggtgaactactgccgtaagagtcaacgctag
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