Clostridioides difficile 630: CD630_02250
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Entry
CD630_02250 CDS
T00487
Symbol
purL
Name
(GenBank) Phosphoribosylformylglycinamidine synthase
KO
K01952
phosphoribosylformylglycinamidine synthase [EC:
6.3.5.3
]
Organism
cdf
Clostridioides difficile 630
Pathway
cdf00230
Purine metabolism
cdf01100
Metabolic pathways
cdf01110
Biosynthesis of secondary metabolites
Module
cdf_M00048
De novo purine biosynthesis, PRPP + glutamine => IMP
Brite
KEGG Orthology (KO) [BR:
cdf00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
CD630_02250 (purL)
Enzymes [BR:
cdf01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.5 Carbon-nitrogen ligases with glutamine as amido-N-donor
6.3.5.3 phosphoribosylformylglycinamidine synthase
CD630_02250 (purL)
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Ortholog
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Gene cluster
GFIT
Motif
Pfam:
GATase_5
AIRS_C
FGAR-AT_linker
TRM
DJ-1_PfpI
Motif
Other DBs
NCBI-ProteinID:
CAJ67046
UniProt:
Q18CW3
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All DBs
Position
288750..292556
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AA seq
1268 aa
AA seq
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MLNTENKDSMVRRVLVEKREGFDLEAKALKKDLVESLHIDNIENLRILNRYDVEGISEEV
YENAAKTIFSEPNLDVVYYEEIPKLNDERVFAIEFLPGQYDQRGDWAAQCVQIVNQGIRP
AINTAKVYILSGKITDEEFSKIKDYCINPVDSREASLEKPETLKMETEIPTTVEVLDGFI
DLDEKGLRTFVSEKGLAMTLGDLQHVQKYFKDTEKRNPTITEIKVLDTYWSDHCRHTTFM
TEIENVKIEDGKFNDIVKEAYQMYLNSRDNVYVNRHKDICLMDIATVAVKELKKNGKLND
LDESEEINACSINVDVEVDGKMEKYLVMFKNETHNHPTEIEPFGGAATCLGGAIRDPLSG
RSYVYQAMRVTGSADPRTTLEDTLPGKLMQRKITTEAAHGYSSYGNQIGLTTGQVAEVYD
ENFVAKRMEIGAVIAAAPKENVVRERPEAGDVIVLLGGKTGRDGCGGATGSSKEHSEESI
LTCSAEVQKGDAPNERKIQRFFRNKEVAQMIKRCNDFGAGGVCVAIGEIADSLDINLDLV
PKKYDGLDGTELAISESQERMAVAIKKENKDKFIQLAVEENLEATHVATVTDTGYLRMFW
NGKAIVDINREFLDTNGVKQTTDVHVTKVDEENTFFSSNEIVKDVKCSSMKDKFTKVLSD
LNVCSQKGLVEMFDNTIGGNTVLMPFGGKYQATPTQGMVAKIPVLGGETNTSTIMTYGYN
PKVGKWSPFHGALYAVVESVCKLVAIGGNYSTTRLTFQEYFEKLGNNPEKWGKPFSALLG
AFYAQSKFEIPAIGGKDSMSGTFKDIEVPPTLVSFAVDTVDAKKVVSPEFKKADSKVVML
CVNKAENDVVDFEELKRNLDKVRELIHGNKVLSTYALGFAGVGEAISKMAFGNKIGFKFS
EEAEKAFTDDKLFEASYGNIVLELANDDLSMLEGYNYVVLGSTVKEASIFIKGEELALDE
LYKAHCSTLEPIFPTKTEEVKSKIETISYISQGEAKKSSLSIATPRVFIPAFPGTNCEYD
SARAFERAGANASIRVFKNLTYKDIEDSIDTIVNEIKSSQIIMLPGGFSAGDEPDGSGKF
IATVFRNPRVQEAINEFLTQKDGLMLGICNGFQVLIKLGLVPYGEIRVPSESAPTLTYNN
IGRHQAKIARTRISSNKSPWLAQTNVGDIHNIAISHGEGKFVASEDVMRELIANGQVATQ
YVDFNNEATYDIEFNPNGSFYAVEGITSADGRVFGKMGHSERIGEEVYKNIIGEKEQKIF
ESGVKYFR
NT seq
3807 nt
NT seq
+upstream
nt +downstream
nt
atgttgaatactgaaaataaagactcaatggttagaagagtattggttgaaaaaagagaa
ggttttgaccttgaggctaaagctttaaaaaaagacttagtagaaagtttacacatagat
aatatagaaaatttaagaatattaaatagatatgatgtagaaggaatatcagaagaagtt
tatgaaaatgcagcaaagacaatattctctgaaccaaatttagatgtggtatattatgaa
gaaataccaaaattaaatgatgaaagagtatttgcaatagaatttcttcctggtcaatac
gaccaaagaggtgattgggcagctcaatgtgtacaaattgtaaatcaagggataagacct
gctattaatacagcaaaagtttatatattatcaggcaaaataactgatgaagagttttct
aaaataaaagattactgtataaatccagtagatagtagagaagcatctttagagaaacca
gaaacgttaaaaatggaaactgaaataccaacaacagttgaagtattagatggatttata
gatttagatgaaaaaggattaagaacatttgtaagtgaaaaaggattagcaatgacttta
ggagacttacaacacgttcaaaaatactttaaagatacagaaaagagaaatccaactata
acagaaataaaagtattagatacttattggtctgatcattgtagacatactacttttatg
actgaaatagaaaatgtaaagatagaagatggtaagtttaatgatatagtaaaagaagcg
tatcaaatgtatcttaactcaagagacaatgtatatgtgaacagacataaagatatatgt
ttaatggatatagccactgttgcagtaaaagaattaaagaaaaatgggaaattaaatgac
ctagatgaaagtgaagaaataaatgcatgtagtataaacgtagatgttgaagttgatggt
aagatggaaaaatatctagtaatgtttaaaaatgaaactcacaaccatccaactgaaata
gaaccatttggtggagcagctacttgtttaggtggagctataagagacccattatcagga
agaagttatgtttatcaagcaatgcgtgttacaggaagtgctgacccaagaacgacttta
gaagatactttacctggaaaacttatgcaaagaaaaataactacagaagctgctcatgga
tatagttcatatggtaaccaaataggtcttacaactgggcaagttgcagaagtatatgat
gaaaactttgttgcaaagagaatggaaataggtgcagttatagcagcagcaccaaaagag
aatgtagtaagagaaagacctgaagcaggagatgtaatcgttcttcttggaggaaaaaca
ggaagagatggctgtggaggagcaactggttcatctaaagaacatagtgaagagtcaatc
ttaacttgtagtgcagaagttcaaaaaggagatgctcctaacgaaagaaaaatacaaaga
ttctttagaaataaagaagttgctcaaatgataaaaagatgtaatgattttggagcaggt
ggagtttgtgttgctataggagagattgctgatagcttagatataaacttagacttagtt
cctaaaaaatatgatggacttgatggaactgagcttgcaatttcagagtcacaagagcgt
atggcagtagccataaaaaaagaaaataaagataaatttatacaattagcagtagaagaa
aacttagaagctacacatgtagctacagtaacagatacaggatatttaagaatgttctgg
aatggaaaagcaattgtagatataaatagagagtttttagatacaaacggagtaaaacaa
actactgatgttcatgttactaaagtagatgaagaaaatacattctttagctctaatgaa
atagtaaaagatgttaagtgttcaagtatgaaagacaagtttacaaaagtactatctgac
cttaatgtttgttctcaaaaaggattagtagagatgtttgataatacaattggtggtaat
acagtacttatgccatttggaggaaagtatcaagcgactccaacacaaggtatggttgct
aagataccagtacttggaggagaaactaatacttctacaataatgacttatggatacaat
ccaaaggtaggaaaatggagtccattccatggtgccttgtatgcagtagtagaatctgtg
tgtaaattggttgctattggaggaaattatagtacaacaagacttacattccaagagtat
tttgaaaaacttggtaacaatccagaaaaatggggtaaaccattctcagcacttttagga
gcattttatgcacaaagtaaatttgagatacctgctataggtggaaaagacagtatgtct
ggtacatttaaagatattgaagttccaccaacattagtttcatttgctgttgacacagta
gatgcgaagaaagtagtatctccagaatttaaaaaagcagactcaaaagtagtaatgtta
tgtgtaaacaaggcagaaaatgatgttgtagattttgaggaattaaagagaaacttagat
aaagtaagagaacttatacatggaaataaagtcttatcaacatatgcattaggatttgca
ggtgtaggtgaagcaataagtaaaatggcttttggtaataaaataggatttaagtttagt
gaagaggctgaaaaagcatttacagatgataaattatttgaggctagttatggaaatata
gtacttgaattagcaaatgatgatttaagtatgttagaaggatacaattatgttgtgctt
ggaagtacagttaaagaagctagtatatttatcaaaggtgaagaacttgcattagatgaa
ttatataaagcacattgtagtactttagagcctatattcccaactaaaacagaagaagta
aaatcaaagatagaaactataagttatatatcacaaggagaagctaaaaaatcatcatta
agtatagctactccaagagtatttataccagcattccctggaacaaactgtgaatatgac
tctgcaagagcatttgaaagagcaggagctaatgcaagtataagagtatttaagaattta
acttataaagacatagaagattctatagatacaatagtaaacgaaataaaatcttctcaa
ataataatgttaccaggtggatttagtgctggtgatgagccagatggttctggtaaattt
atagctactgtatttagaaatcctagagtgcaagaagctataaatgaatttttaactcaa
aaagatggactaatgttaggtatctgtaatggattccaagtattaattaaattagggtta
gttccatatggagaaataagagttccaagtgaaagtgctccaacacttacttacaataat
attggtcgccatcaagctaagattgctagaactagaatttcatctaataaatctccttgg
ttagctcaaactaatgttggagatattcataatatagcaatttctcatggagaaggtaag
tttgttgccagtgaagatgttatgagagaattaattgctaatggacaagtagcaactcaa
tatgttgactttaataatgaagctacttatgatattgagtttaatccaaatggttcattc
tatgctgttgaaggtataactagtgctgatggtagagtgtttggtaaaatgggacattct
gaaagaattggtgaggaagtatataagaatatcataggggaaaaagaacagaagatattt
gaatctggagttaagtattttagataa
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