Clostridioides difficile 630: CD630_26550
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Entry
CD630_26550 CDS
T00487
Symbol
murF
Name
(GenBank) UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase (UDP-MurNAc-pentapeptide synthetase) (D-alanyl-D-alanine-adding enzyme)
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
cdf
Clostridioides difficile 630
Pathway
cdf00300
Lysine biosynthesis
cdf00550
Peptidoglycan biosynthesis
cdf01100
Metabolic pathways
cdf01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
cdf00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
CD630_26550 (murF)
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
CD630_26550 (murF)
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
CD630_26550 (murF)
Enzymes [BR:
cdf01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
CD630_26550 (murF)
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Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
DUF3822
Motif
Other DBs
NCBI-ProteinID:
CAJ69541
UniProt:
Q182Y9
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Position
complement(3063141..3064514)
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AA seq
457 aa
AA seq
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MECLTIKELVLATNGKLIYGDYNDCVSDIVIDSREANAQNAFVAIVGENLDGHTFMKSAY
DSGCKTFIKNESNGIKLESSDINLIDVKDTSLALGDISKYYKEKFDIPFIGVTGSVGKTT
TRDMIYSAISAKLNILKNEKNLNNHFGVPLTLFNLNKEHECAVIEMGMSGFNEIKYLVDI
VNPKIAVISNIGLSHVEKLGSQEGILKAKMEITSNFDETNTLIVNGDDKFLSTLKEKEHV
YKLKTFGFNKNNDVYCESYTMEEDSLTFICVINGKKEEIFIPTIGEHNIYNAMSAILVGL
CLNISLDYIKKGLKNFKGTKMRLDIIKNEKLTIINDSYNASPDSMDAALKILGRYKGRRV
AILGDILEMGEISEYGHRLVGKSSMNNTDIIITIGENSVFIGEEAKQLGFNSANIYHFEN
REDVFNKLNELVKTGDTILVKGSRGMRLEKIVEYLNK
NT seq
1374 nt
NT seq
+upstream
nt +downstream
nt
atggagtgcttaacaataaaagagttagtacttgcaactaatgggaagttaatatatgga
gattataatgactgtgtaagtgatatagttatagatagcagggaggcaaatgcccaaaat
gcatttgtagccatagttggagaaaatttagatgggcatacatttatgaagtctgcatat
gatagtggatgtaaaacttttataaaaaatgaaagtaatggaataaaattagaaagttcg
gatataaatttaatagatgtaaaagatacatctttggctctaggagatatttcaaaatac
tataaagaaaaatttgatattccatttataggtgttacaggtagtgtgggaaaaactact
actagagatatgatttactctgccatatctgcaaagttaaatatactaaaaaatgaaaaa
aacttaaataatcattttggagttccattgactttatttaatctaaataaagaacatgag
tgtgctgtaatagagatgggtatgtctggattcaatgaaataaaatatttagtggatata
gtaaatcctaaaattgcagtcatatcgaatataggattatcacatgtagaaaaactaggt
tcacaagagggtattttgaaagcaaagatggagattacttcaaactttgatgaaacaaat
actttaattgtaaatggagatgataagtttttatctacattaaaagaaaaagaacatgta
tataagttaaaaacatttggctttaataaaaacaatgatgtttattgtgaaagttatact
atggaagaggatagtttaacatttatatgtgtaataaatgggaaaaaagaggaaatattt
ataccaacaataggagaacataatatatataatgcaatgtctgctatattagttggtttg
tgtctaaatatttctttagattatataaaaaaaggtttaaaaaattttaaagggacaaaa
atgagactagacataataaaaaatgaaaaattaacaataattaatgattcatataatgct
agtccagattctatggatgctgctttaaagatacttggaagatataaaggtagaagggta
gcgatacttggagatatactagaaatgggtgaaatttcagagtatggtcatagattagtt
ggaaaatcatctatgaataatactgatattataataactataggtgaaaattcagtgttt
attggagaagaagcaaaacaattaggattcaattcagccaatatatatcactttgagaat
agagaagatgtgtttaacaagttaaatgaattagtaaaaacaggagacactattttagta
aaaggctcaagaggcatgagattagaaaaaatagtcgaatatctaaataaataa
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