Corynebacterium diphtheriae NCTC11397: ERS451417_01624
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Entry
ERS451417_01624 CDS
T04861
Symbol
murF
Name
(GenBank) UDP-N-acetylmuramoylalanyl-D-glutamyl-2%2C 6-diamino pimelate-D-alanyl-D-alanyl ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
cdip
Corynebacterium diphtheriae NCTC11397
Pathway
cdip00300
Lysine biosynthesis
cdip00550
Peptidoglycan biosynthesis
cdip01100
Metabolic pathways
cdip01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
cdip00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
ERS451417_01624 (murF)
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
ERS451417_01624 (murF)
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
ERS451417_01624 (murF)
Enzymes [BR:
cdip01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
ERS451417_01624 (murF)
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Gene cluster
GFIT
Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
Motif
Other DBs
NCBI-ProteinID:
CKH04580
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Position
1:complement(1625577..1627067)
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AA seq
496 aa
AA seq
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MIDLTVEQIAGILGGTLTQGTDPETVVTGPVEFDSRKVSEGSLFVALAGSRVDGHDFVPA
ALESGAAAALVAHPVKIDSGLAPAIVVPPATGQQQSANSYATEHDEDGSIAAVLQGMGLI
ARKVIDTLTAQGLTVMGVTGSAGKTSTKDMLASILSNQAPTVAPPGSFNNEIGHPYTALR
CTEQTRYLVAEMSARGIGHIAHLAQIAPPKIGVVLNVGTAHLGEFGSREIIAQAKGELAE
ALPHDGVAVLNADDDLVAGMRTRTDAKVITFSANSQDADVYATDIELDDYARARFTLHIG
EAENVVTLQVAGQHQVSNALAAAAAAYAAGITIDDIAEALSSHLGASAHRMALMHRSDGA
TIIDDAYNANTESMRAGLTALSTTAHNKSFKGEASHAWAVLGPMSELGEESVAAHEEIGR
LLGELNVHGLIVVGDSADSLALADGARRSNVTTLMARDTAEAADLLDQNMGSADVALVKA
SNAYRLWETAEILASK
NT seq
1491 nt
NT seq
+upstream
nt +downstream
nt
atgattgatctgactgttgaacagatcgcaggtatcttgggtggaacactcacacaaggc
actgatccagaaaccgtagtgacggggcctgtggaatttgactcgcgtaaggtatcggaa
ggttctttgtttgtggcgttggccggatcgcgtgtcgacggccatgatttcgtgccagct
gcgttagaaagtggcgctgcagcagcattggtagcgcatcctgtgaagatcgattctgga
ttagcgcccgctattgtggtgccacctgcgactggtcaacagcaatcggccaacagttac
gcaactgaacatgatgaagacggttcaattgcggctgttctccaaggtatgggacttatt
gcgcgaaaagtcatcgatacgttgactgctcaggggttaaccgtcatgggtgttactggt
tcggcagggaaaacctcgaccaaagacatgttggcgtcaattctgagtaatcaggcccct
accgtggctcctcctggatctttcaataacgagatcgggcatccgtatacagctttacgc
tgtaccgaacagacccgttatctagtagcggagatgtctgcccgcggcattggccacata
gcgcatctagcacagattgcccctcctaaaatcggtgttgtgctcaatgttggcaccgcg
catctaggcgaatttggttcgcgcgaaattattgctcaagccaaaggcgaattagcggag
gcacttcctcacgacggtgtggctgtacttaatgcagatgatgatctcgttgcaggcatg
cgtactcgaactgatgcgaaggtgatcactttttccgcgaattcgcaggacgcggatgtt
tatgccaccgatattgaacttgacgattatgcgcgtgctcgttttaccctccacatcggc
gaagcggagaacgtcgtaacgctccaagttgctggccagcatcaagtttccaatgcactg
gcagctgcagcggcggcatatgcggcaggcataaccattgacgatattgccgaagcattg
agtagccaccttggcgcttctgcgcaccgtatggctcttatgcaccgtagcgatggcgca
accatcattgatgatgcttataacgccaacactgagtcgatgcgtgccggtcttacggcg
ctttccactactgctcacaacaagtcattcaagggcgaagcctcgcacgcgtgggcagtg
ttgggtcccatgagtgagctaggggaggagtcggttgcggcacacgaagagattggcagg
ctcctcggtgagttgaatgtgcatggattaatcgttgtcggagactctgctgattctttg
gcattggcagatggagcccgacgcagcaatgtgactacacttatggctcgcgataccgca
gaagcagcagatctccttgatcagaatatgggttctgcagacgtagctcttgtaaaagca
tctaatgcatatcgtttgtgggaaaccgcagagattttagcttcaaaataa
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