KEGG   Camelus dromedarius (Arabian camel): 105085694
Entry
105085694         CDS       T04642                                 
Symbol
MAP2K6
Name
(RefSeq) dual specificity mitogen-activated protein kinase kinase 6
  KO
K04433  mitogen-activated protein kinase kinase 6 [EC:2.7.12.2]
Organism
cdk  Camelus dromedarius (Arabian camel)
Pathway
cdk04010  MAPK signaling pathway
cdk04015  Rap1 signaling pathway
cdk04218  Cellular senescence
cdk04380  Osteoclast differentiation
cdk04620  Toll-like receptor signaling pathway
cdk04664  Fc epsilon RI signaling pathway
cdk04668  TNF signaling pathway
cdk04750  Inflammatory mediator regulation of TRP channels
cdk04912  GnRH signaling pathway
cdk04935  Growth hormone synthesis, secretion and action
cdk04936  Alcoholic liver disease
cdk05014  Amyotrophic lateral sclerosis
cdk05022  Pathways of neurodegeneration - multiple diseases
cdk05132  Salmonella infection
cdk05135  Yersinia infection
cdk05145  Toxoplasmosis
cdk05161  Hepatitis B
cdk05163  Human cytomegalovirus infection
cdk05167  Kaposi sarcoma-associated herpesvirus infection
cdk05169  Epstein-Barr virus infection
cdk05170  Human immunodeficiency virus 1 infection
cdk05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
cdk05417  Lipid and atherosclerosis
cdk05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:cdk00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    105085694 (MAP2K6)
   04015 Rap1 signaling pathway
    105085694 (MAP2K6)
   04668 TNF signaling pathway
    105085694 (MAP2K6)
 09140 Cellular Processes
  09143 Cell growth and death
   04218 Cellular senescence
    105085694 (MAP2K6)
 09150 Organismal Systems
  09151 Immune system
   04620 Toll-like receptor signaling pathway
    105085694 (MAP2K6)
   04664 Fc epsilon RI signaling pathway
    105085694 (MAP2K6)
  09152 Endocrine system
   04912 GnRH signaling pathway
    105085694 (MAP2K6)
   04935 Growth hormone synthesis, secretion and action
    105085694 (MAP2K6)
  09157 Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    105085694 (MAP2K6)
  09158 Development and regeneration
   04380 Osteoclast differentiation
    105085694 (MAP2K6)
 09160 Human Diseases
  09161 Cancer: overview
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    105085694 (MAP2K6)
  09172 Infectious disease: viral
   05170 Human immunodeficiency virus 1 infection
    105085694 (MAP2K6)
   05161 Hepatitis B
    105085694 (MAP2K6)
   05163 Human cytomegalovirus infection
    105085694 (MAP2K6)
   05167 Kaposi sarcoma-associated herpesvirus infection
    105085694 (MAP2K6)
   05169 Epstein-Barr virus infection
    105085694 (MAP2K6)
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    105085694 (MAP2K6)
   05135 Yersinia infection
    105085694 (MAP2K6)
  09174 Infectious disease: parasitic
   05145 Toxoplasmosis
    105085694 (MAP2K6)
  09164 Neurodegenerative disease
   05014 Amyotrophic lateral sclerosis
    105085694 (MAP2K6)
   05022 Pathways of neurodegeneration - multiple diseases
    105085694 (MAP2K6)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    105085694 (MAP2K6)
   05418 Fluid shear stress and atherosclerosis
    105085694 (MAP2K6)
  09167 Endocrine and metabolic disease
   04936 Alcoholic liver disease
    105085694 (MAP2K6)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:cdk01001]
    105085694 (MAP2K6)
Enzymes [BR:cdk01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.12  Dual-specificity kinases (those acting on Ser/Thr and Tyr residues)
    2.7.12.2  mitogen-activated protein kinase kinase
     105085694 (MAP2K6)
Protein kinases [BR:cdk01001]
 Serine/threonine kinases: STE group
  STE7 family
   105085694 (MAP2K6)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr Kinase-like ABC1 Pkinase_fungal Seadorna_VP7 Choline_kinase Haspin_kinase CLP1_P DUF4344 APH
Other DBs
NCBI-GeneID: 105085694
NCBI-ProteinID: XP_010974258
LinkDB
Position
16:45553777..45676970
AA seq 334 aa
MSQSKGKKRNPGLKIPKEAFEQPQTSSTPPRDLDSKACISIGNQNFEVKADDLEPIVELG
RGAYGVVEKMRHVPSGQIMAVKRIRATVNSQEQKRLLMDLDISMRTVDCPFTVTFYGALF
REGDVWICMELMDTSLDKFYKQVIDKGQTIPEDILGKIAVSIVKALEHLHSKLSVIHRDV
KPSNVLINTLGQVKMCDFGISGYLVDSVAKTIDAGCKPYMAPERINPELNQKGYSVKSDI
WSLGITMIELAILRFPYDSWGTPFQQLKQVVEEPSPQLPADKFSEEFVDFTSQCLKKNSK
ERPTYPELMQHPFFTLHESKGTDVASFVKSILGD
NT seq 1005 nt   +upstreamnt  +downstreamnt
atgtctcagtcgaaaggcaagaagcgaaatcctggccttaaaattccaaaggaagcattt
gaacaacctcagaccagttccacgccacctcgagatttagactccaaagcttgcatttct
attggaaatcagaactttgaggtgaaggcggatgacctggagcccatagtggaactgggg
cgaggtgcctacggggtggtggagaagatgcggcacgtgcccagcgggcagatcatggcg
gtgaagcggatccgggccacagtaaatagccaggagcagaaaaggctactgatggatctg
gatatttccatgaggactgtggactgtccttttacggtcaccttttacggcgcactcttc
cgtgagggtgatgtctggatctgcatggagctcatggatacatccctagacaaattctac
aaacaagtgatcgataaaggccaaacaattccagaggacatcttagggaaaatagcagtt
tctattgtaaaagcattagaacatttacacagtaagctctctgtcattcatcgagatgtc
aagccttccaatgtgctgatcaacaccttgggccaagtgaagatgtgcgattttggaatc
agcggctaccttgtcgactctgtcgctaaaacaattgacgcaggatgcaaaccgtacatg
gctcctgagagaataaacccagagctcaaccagaagggatacagtgtgaaatctgacatt
tggagtctaggcatcaccatgattgagttggccatccttcggtttccctatgattcgtgg
ggaacgccttttcagcagctcaaacaggtagtagaggagccatcaccacaactccccgca
gacaagttctccgaagagtttgttgactttacctcacagtgcttgaagaagaattccaaa
gaaaggccaacatatccagagcttatgcaacatccatttttcactctacacgaatccaaa
ggaacagatgtggcatcctttgtaaaatcaattcttggagactaa

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