KEGG   Camelus dromedarius (Arabian camel): 105086172
Entry
105086172         CDS       T04642                                 
Symbol
EIF2S1
Name
(RefSeq) eukaryotic translation initiation factor 2 subunit 1
  KO
K03237  translation initiation factor 2 subunit 1
Organism
cdk  Camelus dromedarius (Arabian camel)
Pathway
cdk04137  Mitophagy - animal
cdk04140  Autophagy - animal
cdk04141  Protein processing in endoplasmic reticulum
cdk04156  Integrated stress response (ISR) signaling pathway
cdk04210  Apoptosis
cdk04932  Non-alcoholic fatty liver disease
cdk05010  Alzheimer disease
cdk05012  Parkinson disease
cdk05014  Amyotrophic lateral sclerosis
cdk05020  Prion disease
cdk05022  Pathways of neurodegeneration - multiple diseases
cdk05160  Hepatitis C
cdk05162  Measles
cdk05164  Influenza A
cdk05168  Herpes simplex virus 1 infection
cdk05417  Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:cdk00001]
 09120 Genetic Information Processing
  09123 Folding, sorting and degradation
   04141 Protein processing in endoplasmic reticulum
    105086172 (EIF2S1)
 09140 Cellular Processes
  09141 Transport and catabolism
   04140 Autophagy - animal
    105086172 (EIF2S1)
   04137 Mitophagy - animal
    105086172 (EIF2S1)
  09143 Cell growth and death
   04210 Apoptosis
    105086172 (EIF2S1)
   04156 Integrated stress response (ISR) signaling pathway
    105086172 (EIF2S1)
 09160 Human Diseases
  09172 Infectious disease: viral
   05160 Hepatitis C
    105086172 (EIF2S1)
   05164 Influenza A
    105086172 (EIF2S1)
   05162 Measles
    105086172 (EIF2S1)
   05168 Herpes simplex virus 1 infection
    105086172 (EIF2S1)
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    105086172 (EIF2S1)
   05012 Parkinson disease
    105086172 (EIF2S1)
   05014 Amyotrophic lateral sclerosis
    105086172 (EIF2S1)
   05020 Prion disease
    105086172 (EIF2S1)
   05022 Pathways of neurodegeneration - multiple diseases
    105086172 (EIF2S1)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    105086172 (EIF2S1)
  09167 Endocrine and metabolic disease
   04932 Non-alcoholic fatty liver disease
    105086172 (EIF2S1)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03012 Translation factors [BR:cdk03012]
    105086172 (EIF2S1)
   04131 Membrane trafficking [BR:cdk04131]
    105086172 (EIF2S1)
Translation factors [BR:cdk03012]
 Eukaryotic type
  Initiation factors
   eIF-2
    105086172 (EIF2S1)
Membrane trafficking [BR:cdk04131]
 Autophagy
  ER-phagy
   ER stress-related proteins
    105086172 (EIF2S1)
SSDB
Motif
Pfam: EIF_2_alpha S1
Other DBs
NCBI-GeneID: 105086172
NCBI-ProteinID: XP_010974921
UniProt: A0A5N4E4V1
LinkDB
Position
6:66058983..66075901
AA seq 315 aa
MPGLSCRFYQHKFPEVEDVVMVNVRSIAEMGAYVSLLEYNNIEGMILLSELSRRRIRSIN
KLIRIGRNECVVVIRVDKEKGYIDLSKRRVSPEEAIKCEDKFTKSKTVYSILRHVAEVLE
YTKDEQLESLFQRTAWVFDDKYKRPGYGAYDAFKHAVSDPSILDSLDLNEDEREVLINNI
NRRLTPQAVKIRADIEVACYGYEGIDAVKEALRAGLNCSTETMPIKINLIAPPRYVMTTT
TLERTEGLSVLNQAMAVIKEKIEEKRGVFNVQMEPKVVTDTDETELARQLERLERENAEV
DGDDDAEEMEAKAED
NT seq 948 nt   +upstreamnt  +downstreamnt
atgccgggtctaagttgtagattttatcagcacaaatttcctgaggtggaagatgtagtg
atggtgaacgtaaggtctattgctgaaatgggggcttatgtcagcttgctggaatacaac
aacatcgaaggcatgattcttctgagtgagttgtccagaaggcgtattcgttctataaac
aaactcatccggattggcaggaatgaatgtgtggttgtcattagagtggacaaagaaaaa
gggtatattgatttgtcaaaaagaagagtttctccagaggaagcaatcaaatgtgaagac
aaattcaccaaatccaaaactgtttacagcattctgcgtcatgttgctgaggtgttagaa
tacaccaaggacgagcagctggaaagcctgttccagaggactgcctgggtctttgatgac
aagtacaagagacccggatatggtgcctatgatgcatttaagcatgcagtctcagaccca
tctattttggatagtttagatttgaatgaagatgaacgggaagtactcattaacaatatt
aataggcgtttgaccccacaggctgtcaaaattcgagcagatattgaagtggcttgttat
ggttatgaaggcattgatgccgtaaaagaagccctgagagcaggtttgaattgttcaaca
gaaaccatgcccatcaagattaatctaatagctcctcctcggtatgtaatgaccacaacc
accctggagagaacagaaggcctctctgtccttaatcaagctatggctgttataaaagaa
aagattgaggaaaagaggggtgtcttcaatgttcaaatggagcccaaagtggtcacagat
acagatgagacggaacttgcaaggcagctggagaggcttgagagagaaaatgccgaagta
gatggagatgatgatgcggaagaaatggaagccaaagccgaagattaa

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