Camelus dromedarius (Arabian camel): 105087635
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Entry
105087635 CDS
T04642
Symbol
PDE4A
Name
(RefSeq) cAMP-specific 3',5'-cyclic phosphodiesterase 4A isoform X1
KO
K13293
cAMP-specific phosphodiesterase 4 [EC:
3.1.4.53
]
Organism
cdk
Camelus dromedarius (Arabian camel)
Pathway
cdk00230
Purine metabolism
cdk01100
Metabolic pathways
cdk04024
cAMP signaling pathway
cdk04928
Parathyroid hormone synthesis, secretion and action
cdk05032
Morphine addiction
Brite
KEGG Orthology (KO) [BR:
cdk00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
105087635 (PDE4A)
09130 Environmental Information Processing
09132 Signal transduction
04024 cAMP signaling pathway
105087635 (PDE4A)
09150 Organismal Systems
09152 Endocrine system
04928 Parathyroid hormone synthesis, secretion and action
105087635 (PDE4A)
09160 Human Diseases
09165 Substance dependence
05032 Morphine addiction
105087635 (PDE4A)
Enzymes [BR:
cdk01000
]
3. Hydrolases
3.1 Acting on ester bonds
3.1.4 Phosphoric-diester hydrolases
3.1.4.53 3',5'-cyclic-AMP phosphodiesterase
105087635 (PDE4A)
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Gene cluster
GFIT
Motif
Pfam:
PDEase_I
PDE4_UCR
Motif
Other DBs
NCBI-GeneID:
105087635
NCBI-ProteinID:
XP_031293136
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Position
22:complement(7191244..7225632)
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AA seq
845 aa
AA seq
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MARPRGLGRDPELQLVAFPAAAAAATEDEAFLPEPPARRSPRRPRSPPSSPVFFASPSPT
FRRRLRLLRSFQDFGRQAWAGFEAENGPTPSPGRSPLDSQASPGLVLHAGVATSQRRESF
LYRSDSDYDMSPKTMSRNSSVTSEAHAEDLIVTPFAQVLASLRSVRSNFSLLTNVPIPTN
KWSPLGGPTPVCKATLSEETCQQLAKETLEELDWCLEQLETMQTYRSVSEMASHKFKRML
NRELTHLSEMSRSGNQVSEYISTTFLDKQNEVEIPSPKMKDRDKQQAPRQRPSQQPPPPG
PQFQPMSQITGVKKLMHSSSLNDSNIPRFGVKTDQEELLAQELENLNKWGLNIFCVSDYA
RGRSLSCIMYTIFQERDLLKKFRIPVDTMVTYMLTLEDHYHPDVAYHNSLHAADVLQSTH
VLLATPALDAVFTDLEILAALFAAAIHDVDHPGVSNQFLINTNSELALMYNDESVLENHH
LAVGFKLLQEDNCDIFQNLSKRQRQSLRKMVIDMVLATDMSKHMTLLADLKTMVETKKVT
SSGVLLLDNYSDRIQVLRNMVHCADLSNPTKPLELYRQWTDRIMAEFFQQGDRERERGME
ISPMCDKHTASVEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEDNRDWYYSAIRQS
PSPPPEEEPGGPGHPPPPDKFQFELTLEEEEEEELSTAPGKIGVQELSTAQDASPAEDPL
EVDGQYRSTEVEVEEMYLTQQKDSADSVAPGQDESASPDASVDAVGCSLLPALSPEGPPL
PALRTPPPAEEDPGLLGLPSMAAEVGAQKEHQAAKRACCACTGTSSEDPPTLPTPGGWGS
AGDLT
NT seq
2538 nt
NT seq
+upstream
nt +downstream
nt
atggcgcggccgcgcggcctgggccgcgatcccgaactgcagctggtggccttcccggcg
gcggcagcggcggccaccgaggacgaggcgttcctgcccgagcccccggcccggcgctcg
ccccgccgcccacgttcgccgccttcttcgccggtcttctttgccagcccgtccccaact
ttccgcaggcgccttcggcttctccgcagctttcaggatttcggccgccaggcttgggcc
ggcttcgaggcggagaatgggccgacgccatcgccaggccgcagccccctggactcgcag
gcgagcccgggcctcgtgctgcatgccggggtggccaccagccagcgccgagagtccttc
ctctaccgctcagacagtgactatgacatgtcacccaagaccatgtcccggaactcgtcg
gtcaccagcgaggcgcatgcagaggacctcattgtgacgccgttcgcccaggtgctggcg
agtctccggagcgttcgcagcaacttctcactcctgaccaatgtgcccattcccaccaac
aagtggtccccgctgggcggcccaacccccgtctgcaaggccacactgtcagaggagacg
tgtcagcagttggccaaagagacgttggaggaactggactggtgtttggagcagctggag
accatgcagacttaccgctccgtcagtgagatggcgtcccacaagttcaagaggatgcta
aaccgtgaactcacacacctgtcagagatgagcaggtcaggaaaccaggtctctgagtac
atctccaccacattcctggacaagcagaatgaagtggaaatcccatcacccaagatgaag
gatagagataaacagcaagcaccacgacagagaccctcccagcagcccccgcccccgggg
ccacagttccagcccatgtctcagatcactggcgtgaagaaactgatgcatagcagcagc
ctgaacgattccaacatccctcgctttggggtgaagaccgaccaagaggaactcctggcc
caagaactagagaacctgaacaagtggggcctgaacatcttttgcgtgtcggattacgcc
aggggccgttccctcagctgcatcatgtacacgatattccaggagcgggacctgctgaag
aagttccgcatcccggtggacacgatggtaacatatatgctgaccctggaggaccattac
caccctgatgtggcctaccacaacagcctgcacgcggcggacgtgctgcagtccacccac
gtgctgctggccacacctgcgctggacgccgtgttcacggacttggagattcttgctgct
ctcttcgcggctgccatccatgacgtggaccaccctggggtctccaaccagttcctcatc
aacaccaattcagagctggcgctcatgtacaacgatgaatcggtgctggagaaccaccac
ctggccgtgggcttcaagctgctgcaggaagacaactgtgacatcttccagaacctcagc
aagcgccagcggcagagcctgcgcaagatggtcatcgacatggtgctggccacggacatg
tcaaagcacatgaccctcctggctgacctgaagaccatggtggagaccaagaaagtgacc
agctcgggggtcctcttgttggataactattccgaccgcatccaggtcctgaggaacatg
gtgcactgcgcagacctcagcaaccccaccaagccgctggagctgtaccgccagtggacc
gatcgcatcatggctgagttcttccagcagggcgaccgtgaacgcgagcgtggcatggag
atcagccccatgtgcgacaagcacacggcctcggtggagaagtctcaggtgggtttcatt
gactatattgtacatccgctgtgggagacatgggctgacttggtccacccagatgcccaa
gatatcctggacacactggaggacaaccgggactggtactacagtgccatccgacagagc
ccatcgccaccacccgaggaggagcctgggggaccaggccaccctcccccaccagataag
ttccaatttgaactgacgctggaggaggaagaggaggaggagttgtccaccgccccgggt
aaaattggagtgcaggaattgtccacagcccaggatgcatcccccgctgaggacccgttg
gaggtggatggccagtaccggtctacagaggtggaggtagaggaaatgtacttgacacag
caaaaagactcggcagatagtgtggctccaggccaggacgagtccgcgtccccagatgca
tctgtggatgctgtaggctgcagccttctccctgccctgtctcctgagggcccccctctg
cctgccttgaggaccccgccccctgcagaggaggacccgggccttctgggcctcccctcc
atggcggccgaggtgggggcccaaaaagagcatcaggctgccaagagggcatgctgtgcc
tgcacagggacatccagcgaggacccacccacactcccaactcctggagggtgggggtca
gctggagaccttacctga
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