Camelus dromedarius (Arabian camel): 105088819 Help Entry 105088819         CDS       T04642                                  Symbol PKLR Name (RefSeq) pyruvate kinase PKLR isoform X1   KO K12406   pyruvate kinase isozymes R/L [EC:2.7.1.40] Organism cdk  Camelus dromedarius (Arabian camel) Pathway cdk00010   Glycolysis / Gluconeogenesis cdk00620   Pyruvate metabolism cdk01100   Metabolic pathways cdk01200   Carbon metabolism cdk01230   Biosynthesis of amino acids cdk04910   Insulin signaling pathway cdk04930   Type II diabetes mellitus cdk04932   Non-alcoholic fatty liver disease cdk04950   Maturity onset diabetes of the young Module cdk_M00001   Glycolysis (Embden-Meyerhof pathway), glucose => pyruvate cdk_M00002   Glycolysis, core module involving three-carbon compounds Brite KEGG Orthology (KO) [BR:cdk00001]  09100 Metabolism   09101 Carbohydrate metabolism    00010 Glycolysis / Gluconeogenesis     105088819 (PKLR)    00620 Pyruvate metabolism     105088819 (PKLR)  09150 Organismal Systems   09152 Endocrine system    04910 Insulin signaling pathway     105088819 (PKLR)  09160 Human Diseases   09167 Endocrine and metabolic disease    04930 Type II diabetes mellitus     105088819 (PKLR)    04950 Maturity onset diabetes of the young     105088819 (PKLR)    04932 Non-alcoholic fatty liver disease     105088819 (PKLR)  09180 Brite Hierarchies   09183 Protein families: signaling and cellular processes    04147 Exosome [BR:cdk04147]     105088819 (PKLR) Enzymes [BR:cdk01000]  2. Transferases   2.7  Transferring phosphorus-containing groups    2.7.1  Phosphotransferases with an alcohol group as acceptor     2.7.1.40  pyruvate kinase      105088819 (PKLR) Exosome [BR:cdk04147]  Exosomal proteins   Exosomal proteins of other body fluids (saliva and urine)    105088819 (PKLR) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  PK PK_C IMPDH HpcH_HpaI Neuregulin Motif Other DBs NCBI-GeneID:  105088819 NCBI-ProteinID:  XP_010978076 LinkDB All DBs Position 21:23000573..23008906 Genome browser AA seq 556 aa AA seqDB search MEPTPRDRQLCSGMEGPAGYLRRASVAQLTQELGIAFFQRQQLPAAMADTFLEHLCLLDI DSEPMAARSTSIIATIGPASRSVERLKEMIKAGMNIARLNFSHGSHEYHAESIANIREAV ESFATSPFSYRPVAIALDTKGPEIRTGILQGGPASEVQLVKGSQVLVTVDLEFRTRGDAN TVWVDYPNIVRVVPVGGRIYIDDGLISLVVKKIGPEWLETQVENGGVLGSRKGVNLPGTQ VDLPGLSEQDVQDLRFGVEHGVDIIFASFVRNASDVAAVRAALGPEGQGIKIISKIENHE GVKKFDEILEVSDGIMVARGDLGIEIPAEKVFLAQKMMIGRCNLAGKPVVCATQMLESMI TKPRPTRAETSDVANAVLDGADCIMLSGETAKGNFPVEAVKMQHAIAREAEAAVYHRQLF EELRRAAPLSRDPTEVTAIGAVEAAFKCCASAIIVLTTTGRSAQLLSRYRPQAAVIAVTR SAQAARQAHLCRGVFPVLYREPPEAIWADDVDRRVQFGIESGKLRGFLRSGDLVIVVTGW RPGSGYTNIMRVLSIT NT seq 1671 nt NT seq  +upstreamnt  +downstreamnt atggagccgactcccagagacagacagctgtgcagtggcatggaggggccagcagggtac ctgcggcgggccagcgtggcccagctgacccaggagctgggcattgccttcttccagcgg cagcagctgccggcagccatggcagacaccttcctggagcacctctgcctgctggacatc gactccgagcccatggccgctcgcagtaccagcatcattgccaccatcgggccggcatct cgctccgtggagcgcctcaaggagatgatcaaggccgggatgaacattgcgcgactcaac ttctcccacggctcccacgagtaccacgctgagtccatcgccaacatccgggaggcggtg gagagctttgcaacttccccgttcagctaccgacccgtggccatagctctggacaccaag ggaccggagatacgcactgggatcctgcaggggggcccggcgtcggaagtgcagctagtg aagggctcccaggtgctagtgaccgtggacctggagttccggacgcggggggacgcgaac accgtgtgggtggactaccccaatatcgtccgggtcgtgccggtggggggccgcatctac attgacgacgggctcatctccctagtggtcaagaaaatcggtccagagtggctagagacc caagtggaaaatggcggtgtcctgggcagccggaagggcgtgaacttgccgggcacccaa gtggacctgcccgggctgtctgagcaagatgtccaggacctgcgcttcggggtggaacat ggcgtggacatcatctttgcctcctttgtgcggaatgccagcgacgtggctgccgtcagg gctgctctggggccggaaggacagggcatcaagatcattagcaaaattgagaaccatgaa ggcgtcaagaagtttgatgaaatcctggaagtgagcgatggcattatggttgcacggggt gacctgggcattgagatcccagcggagaaggttttcctggctcagaagatgatgattggc cgttgcaacttggcgggcaagcctgtcgtctgtgctacacagatgttggagagcatgatc actaagcctcggccaactcgggcagagacaagtgatgtggccaacgccgtgctggatgga gcagactgcatcatgctgtcgggggagactgccaagggcaactttcctgtggaggctgta aagatgcagcatgcgattgcccgggaggcagaggctgcagtgtaccaccggcagctcttt gaggagctgcgccgggcggcaccgctgagccgggatcccacagaggtcaccgctattggc gctgtggaggctgccttcaagtgctgtgcctctgccatcatcgtgctgaccacaactggc cgttcagcacagcttctgtctcggtaccgacctcaggcagcagtcattgctgtcacccgc tctgcccaggctgcccgccaggcccacctatgccgaggagtcttccctgtgctctaccgt gaacctccagaggccatctgggcagacgatgtggatcgccgggtccaatttggcattgaa agtggaaagctccgtggcttcctccgttctggggacctggtgattgtggtgacaggctgg cgaccaggctctggctataccaacatcatgcgagtgctgagcataacctga

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