Camelus dromedarius (Arabian camel): 105089274
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Entry
105089274 CDS
T04642
Symbol
LRRK2
Name
(RefSeq) leucine-rich repeat serine/threonine-protein kinase 2 isoform X1
KO
K08844
leucine-rich repeat kinase 2 [EC:
2.7.11.1
]
Organism
cdk
Camelus dromedarius (Arabian camel)
Pathway
cdk05012
Parkinson disease
cdk05022
Pathways of neurodegeneration - multiple diseases
Brite
KEGG Orthology (KO) [BR:
cdk00001
]
09160 Human Diseases
09164 Neurodegenerative disease
05012 Parkinson disease
105089274 (LRRK2)
05022 Pathways of neurodegeneration - multiple diseases
105089274 (LRRK2)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
cdk01001
]
105089274 (LRRK2)
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:
cdk04131
]
105089274 (LRRK2)
09183 Protein families: signaling and cellular processes
04147 Exosome [BR:
cdk04147
]
105089274 (LRRK2)
Enzymes [BR:
cdk01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.1 non-specific serine/threonine protein kinase
105089274 (LRRK2)
Protein kinases [BR:
cdk01001
]
Serine/threonine kinases: TKL group
LRRK family
105089274 (LRRK2)
Membrane trafficking [BR:
cdk04131
]
Exocytosis
Calcium ion-dependent exocytosis
Kinases and associated proteins
105089274 (LRRK2)
Exosome [BR:
cdk04147
]
Exosomal proteins
Exosomal proteins of other body fluids (saliva and urine)
105089274 (LRRK2)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
ARM_LRRK2
Beta-prop_LRRK2
ANK_LRRK2
Pkinase
PK_Tyr_Ser-Thr
LRR_8
LRR_4
Roc
COR
Ras
LRR_9
LRR_14
Arf
WDR55
WD40_CDC20-Fz
Beta-prop_RSE1_2nd
G-alpha
Beta-prop_EML_2
Beta-prop_BBS7
LRR_NXF1-5
LRR_13
Ank_2
WD40_Prp19
Kdo
Beta-prop_EML
GTP_EFTU
LRR_6
MMR_HSR1
MobB
PduV-EutP
T2SSE
nSTAND3
TniB
Motif
Other DBs
NCBI-GeneID:
105089274
NCBI-ProteinID:
XP_010978604
LinkDB
All DBs
Position
12:complement(19241133..19376605)
Genome browser
AA seq
2558 aa
AA seq
DB search
MGRAGRGRGAALPPFPEPRPWCRFGAASVMASGSCQGCEEEEDEETLKKLIVRLNNVQEG
KQIETLVQILEDMLVLTYADYASKLFQDKNVHVPLLIVLDSYMRVASVQQVGWSLLCKLI
EICPNTMQSLMGPQDIGNDWEVLGVHQLILKMLTVHNASVTLSTVGLKTLDLLLTSGKIT
LLILEEEHDIFLLIFDAMRTFSANDEIQKLGCKALHVLFEKVSEEQLTEFVENKDYMILL
SALNSFKDEEEIVLHVLHCLHSLAIPCNNVEVLMSGNVRCYNIVVEAMKAFPINEKIQEV
SCCLLHRLTLGNFFNILVLNEVHEFVVKAVQRYSKNADLQIAALSCLALLTETIFLNQDL
EEKNEHQENEEEEEEEKLFWLEACYKALTWHRKNKHVQEAACWALNNLLMYQNSLHEKIG
DEDGQFPAHREVMLSMLMHSSSKEVFQASANALSTLLEQNVNFRKILLSKGIYLNVLELM
QKHIHSPEAAESGCKMLNHLFEGSNTSLDTMAAVAPKIITVMKSHQTSLSVQLEALRAIL
HFIVPGFPEESTEDCEYQHKLNMVKKQCFRNDIHKLVLAAVNRFIGNPGIQKCGLKVISS
IACFPDALEVLTLEGAVDSVLHTLQMYPDDQEIQCLGLSLIGCLITKKNLCTGTGHLLAK
ILISSLQRFKDIGEVQIKGFQAIFTILELSVSFSKLLLQHSFDSVIFHQMSSGVLEQKDQ
QFLSLCCKCFAKLALDDELKSVMLQRACDQNNSIMVECLLLLGADANRAKEATSLICQVC
EKASSPKLVELLLDSGSREQDVRRALTVSIGKGDSRIISLLLRRLALDLANNSICLGGFC
MGKIEPSWLGPLFPDKTSQLRKETNMGSTLARMVLRYQMKSAVEEGAASGSNGNLSEEIL
DKFDEWTFIPESYVDSVFGQSDDLDSEGSEGSFLVKKKSNSISVGEFYRDPALQRCSPNL
QRHSSSLGPIFDHEDLLKRKRKILSSDDSLRTSKLQSHVRHSDSVSSLASERDCITSLDL
SANELRDIDALSQKSCISGHLEHLEKLELHQNALTSFPQQLCETLKCLTHLDLHSNKFTS
FPPYLLKMNCIANLDVSRNDIGPSVVLDPAVKCPTLKQLNLSYNQLSSLPENLGDVVEKL
EQLILEGNKISEICSPLSLKELKILNLSKNHISSLSEDFLETCPKVESLSARMNFLVAMP
FLPSSMTSLKLSQNRFTCVPEAILSLPHLRSLDMSSNDIQYLPGPVHWRSLNLRELLFSH
NRISVLDLSEKACAWSRVEKLHLSHNKLKEIPPEIGCLENLTSLDVSYNLELRSFPNEMG
KLSKIWDLPLDELHLNFDFKHIGCKAKDIIRFLQQRLKKAVPYNRMKLMIVGNTESGKTT
LLQQLMKIKKSDLGMQGATVGIDVKDWPIQVRGKGKKDLILNVWDFAGREEFYSTHPHFM
TQRALYLAVYDLSKGQAEVDAMKPWLFNIKARASSSPVILVGTHLDVSDEKQRKACIGKI
TKELLNKRGFPAIRDYHFVNATEESDALAKLRKTIINESLNFKIRDQPVVGQLIPDCYVE
LEKIILSERKNVPTEFPVIDRKRLLQLVEDHQLQLDENELPHAVHFLNESGVLLHFQDPA
LQLSDLYFVEPRWLCKVMAQILTVKVEGCPKHPKGIISRRDVEKFLSKKKRFPKNYMSQY
FKLLEKFQIALPNGEENLLVPSSLSDQRPVIELPHCENSEIIIRLYEMPYFPMGFWSRLI
NRLLEISPYMLSGREQALRPNRMYWRQGIYLIWSPEAYCLVGSEVLDNHGESFLKITVPS
CRKGCILLGQVVDHIDSLMEEWFPGLLEIDICGEGETLLKKWALYSFNDGEEHQKILLDD
LMKKAEEGDLLINPDQPRLTIPISQIAPDLILADLPRSIMLNNDELEFEQAPEFLLGDGS
FGSVYQATYEGEEVAVKIFNKHTSLRLLRQELVVLCHLHHPSLVSLLAAGIRPRMLVMEL
ASKGSLDRLLQQDKASLTRTLQHRIALHVADGLRYLHSAMIIYRDLKPHNVLLFTLYPNA
AIIAKIADYGIAQYCCRMGIKTSEGTPGFRAPEVARGNVIYNQQADVYSFGLLLYDILTT
GGRIAEGLKFPNEFDELAIQGKLPDPVKEYGCAPWPMVEKLIKKCLKENPQERPTSAQVF
DILNSAELICLMRRISIPKNFTVECMVASNHISKNASIWLGCGHTDKGLLSLLDLNTERY
ISEEVTDSRILCLALVHLPVEKESWIVSGTQSGTLLAINTEDERKRHTLEKMTDSVTCLY
CHSFSRQSKQKNFLLVGTADGNLAIFEGKTVKCKGAAPLKILNIGNVSTPLMCLSESMNS
TEKNIMWGGCGTKIFSFSDDFTIQKLIESRTNQLFSYASYSDSNIIAVVVDTVLYVAKKN
SPFVEVWDKKTEKLCELIDCVHFLKEELVKVNKESKHKMSYSGRVKTLSLQKNTALWIGT
GGGHILLLDLSTRRIIRIIHNFCDSVRVMMTAQLGNLKNVMLVLGYNRKNTEGMQHQKEI
QSCLSVWDINLPHEVQNLEKHIEVRKELAEKMRRISVE
NT seq
7677 nt
NT seq
+upstream
nt +downstream
nt
atggggcgcgccggccgcgggcggggagctgcgctcccacccttcccggagccgcggcct
tggtgcaggtttggagcagcgtctgtcatggccagtggcagctgccagggctgcgaggag
gaggaggacgaggaaactctgaagaagttgatagtcaggctgaacaatgtccaggaagga
aaacagatagagacgctggtccaaatcctggaggatatgctggtgctcacttatgccgac
tacgcctccaagttatttcaagacaaaaatgtccacgtgcctctgttgatcgtcttggac
tcgtatatgagagtcgctagcgtgcagcaggtgggttggtcacttttatgcaaattaata
gaaatctgtccaaatacaatgcaaagcttaatgggaccccaggatattggaaacgattgg
gaagttcttggggttcaccaactgattcttaaaatgctaacagttcataatgccagtgtc
accctgtcaacggttggattgaagaccttagatctccttctaacatcaggtaaaatcact
ttgctgatattggaggaagaacatgatattttcttgttaatttttgatgccatgcgcaca
ttttcagccaatgatgaaatccagaaacttggatgcaaagctttacatgtgctgtttgaa
aaagtttcagaggagcaactgactgaatttgtcgaaaataaagattatatgatactgcta
agtgcgttaaacagttttaaggatgaagaggaaattgtgctgcatgtattgcactgttta
cattccctagcgattccttgcaataatgttgaagtcctcatgagtggcaatgtcagatgt
tataatattgtggtagaagccatgaaagcattccctatcaatgaaaaaattcaagaagtg
agttgctgcttgctgcataggcttacattaggtaatttttttaatatcttggtgttaaac
gaggtgcatgagttcgtggtaaaagccgtgcagcgatattcaaagaacgcagacttacag
atcgcggcactcagctgtttggcgctcctcactgagaccattttcttaaatcaagactta
gaggaaaagaatgagcatcaggagaatgaggaggaggaggaagaagaaaagttgttttgg
ctggaagcctgttacaaagcattgacatggcacagaaagaacaagcatgtgcaggaggcc
gcatgctgggccctgaacaatctcctcatgtatcaaaacagtttacacgagaagattgga
gatgaagatggccagttcccggctcacagggaagtgatgctgtccatgctaatgcattct
tcttcaaaagaagtcttccaggcatctgcaaatgcgttgtcgactctgttagaacaaaat
gttaatttcagaaaaatcctgttgtcaaaaggaatatatctgaatgtgttggaattaatg
cagaagcatatacattctcctgaggcggctgaaagcggctgtaaaatgctaaatcatctt
tttgaaggaagtaacacctccctggatacaatggcagcagtggcccccaaaataataaca
gttatgaaaagtcatcagacatcgttatcagtgcagctggaggcacttcgagctatttta
cattttatagttccaggcttcccagaagaatccacggaagactgtgaatatcaacataag
ctaaatatggttaaaaaacaatgtttcaggaatgatattcacaaactggtcctagcagcc
gtgaacaggttcattggaaatcctgggattcagaaatgtggattaaaagtaatttcttct
atagcatgttttcctgatgcattagaggtgttaaccctggaaggtgctgttgattcggtg
ctccacacgctgcagatgtatccggatgaccaagaaattcagtgtctgggtttgagtctt
ataggatgcttgattacaaagaagaatttatgcacagggactgggcatcttttggcaaaa
attctgatttccagcttacaacgatttaaggatattggtgaagtacagattaaaggattt
caggcgatctttacgatactggagttgtcagtgtctttttccaagctactgctgcagcat
tcctttgattcagtaatattccatcagatgtcttccggtgtcctggaacaaaaggatcag
cagtttctaagcctctgttgcaagtgctttgcaaaactagctctggatgatgaattaaag
agcgtgatgctccagagggcgtgtgatcagaataacagcatcatggttgaatgcttgctt
ctgttgggagcggacgccaatcgagcaaaagaggcaacctctttaatttgtcaggtgtgt
gagaaagcgagcagtcccaaactggtggaactgttactggacagtgggtcccgggaacaa
gatgtgcggagagctctgacagtcagcattgggaaaggtgacagccggatcatcagccta
cttttaaggaggcttgccctggatctggccaataatagcatttgccttggaggattttgt
atgggcaaaattgaaccttcttggctgggtcctttatttccagataagacatctcagtta
aggaaagaaacaaatatgggctccaccctagcaagaatggtgctcagatatcagatgaaa
agtgctgtggaagaaggagcagcctcaggcagcaatggcaatctttctgaagaaatactg
gataaatttgacgaatggaccttcattcctgagtcttacgtggacagtgtgtttggtcaa
agtgatgacctggatagtgaaggaagtgaaggctcatttcttgtgaaaaagaaatcaaat
tcaattagcgtaggagaattttaccgagatcctgccttgcagcgttgctcaccaaatttg
caaagacattccagttcgttgggacccatttttgatcatgaagatttactgaagagaaaa
agaaaaatactgtcctcagatgattcactcagaacgtcaaaactccagtcacatgtgagg
cattcagacagcgtttcttccctggcttctgagagagactgtattacatcattagacctt
tcagccaatgaactcagagatattgacgccctgagccagaagtcctgcataagcggtcat
ctggagcaccttgaaaagctggagcttcaccagaatgcactcacgagctttccacaacaa
ctctgtgaaactctgaagtgtttgacacatttggacttgcacagtaataaatttacatca
tttcctccctacttgttgaaaatgaattgtattgccaacctcgatgtctctcgaaacgac
attggaccctcagtagttttggatcctgctgtgaagtgcccgaccttgaaacagcttaac
ctctcctataatcagctgtcttctcttcctgagaaccttggtgatgtggtagagaaactg
gagcagctcattttagaaggcaataaaatatcagaaatatgttcccctttgagcctgaag
gaactgaagattttaaaccttagtaaaaaccacatttcatctctgtcggaggactttctg
gagacttgtcctaaagtggagagtttaagtgccaggatgaattttcttgttgctatgcct
tttttgccttcctccatgacaagcctaaaattatctcagaacagattcacatgtgttccg
gaagcaattttaagtcttccacacctgcggtccttagatatgagcagcaatgatattcag
tatctgccgggtcctgtgcactggagatctctgaacttacgggaactcttgtttagccat
aatcggatcagtgtcttggacttgagtgaaaaagcctgtgcctggtctagagtagagaaa
ctacatctttcccataataaactgaaagagattcctcccgagattggctgtctggaaaac
ctgacatctcttgatgttagttacaacttggaactgagatcttttcccaatgaaatgggg
aaattaagcaaaatatgggatcttcctttggatgaactgcatcttaattttgattttaaa
catataggatgtaaagccaaagacatcataaggttccttcagcagcggttaaaaaaggct
gtgccttataaccgaatgaagcttatgattgtgggaaatactgagagcggtaaaaccacc
ttattgcagcaattaatgaaaatcaagaaatcagatcttgggatgcaaggtgccacagtt
ggcatagacgtgaaagactggcccatccaagtaagaggcaaagggaagaaagaccttatt
ctaaacgtgtgggattttgcaggtcgtgaggagttctacagcactcatccccacttcatg
acccagcgagccctgtatcttgctgtctatgacctcagcaaagggcaagctgaagtggac
gccatgaagccttggctcttcaatataaaggcgcgtgcttcttcttcgcccgtgattctt
gttggcacacatttggatgtttctgatgagaagcagcgcaaagcctgtataggtaaaatc
accaaggagctcttgaacaagcgagggtttcctgccatacgggattaccactttgtaaat
gccacggaggaatccgacgctttggcaaaacttcggaaaaccatcattaatgagagcctg
aatttcaagatccgagatcagcctgttgttgggcagctgattccagactgctatgtagaa
cttgagaaaatcattttatcggagcgtaaaaatgtgccaactgaatttcctgtaattgac
cggaaacgattattacagctcgtggaagaccatcagctgcagttggatgaaaatgagctc
cctcatgcagttcacttcctaaatgaatcaggggttcttcttcattttcaagacccagca
ctgcagttaagtgatttatattttgtggaacccaggtggctttgtaaagtcatggcacag
attttgacagtgaaagtggaaggctgtcccaaacatcctaagggaattatttcacgtaga
gatgtggagaagtttctttcgaagaaaaagagatttccaaagaactacatgtcacaatac
tttaaactcctagagaaattccagattgccttgccaaacggtgaagaaaatttgctggtc
ccaagcagtctgtctgaccaaaggcctgtgatagagctcccgcactgtgagaactctgaa
attatcattcggctctacgaaatgccttattttccaatgggcttttggtcgagattaatc
aatcgattacttgaaatttcaccttacatgctttcaggaagagagcaagcacttcgccca
aacagaatgtactggcgacaaggcatctacctgatctggtctcctgaagcttactgcctg
gtaggatctgaagtcttagacaatcacggggagagtttcttaaaaattacagttccttct
tgtagaaaaggctgtattcttttgggccaagttgtggaccacattgattctctcatggaa
gagtggtttcctgggttattggagattgatatttgtggcgaaggagaaactctgttgaag
aaatgggccttgtatagttttaacgatggggaagagcatcaaaaaatcttacttgacgac
ttgatgaagaaagcagaagaaggagaccttctaataaatccagatcaaccaaggctcacc
attccaatatctcagattgcccctgacttgattttggctgacctgcctagaagcattatg
ttgaacaatgatgaactggaatttgaacaagctccagagtttctcttaggcgatggcagt
tttggatccgtttatcaagcaacctatgaaggagaagaagtggctgtgaagatctttaat
aaacatacatcactcagactgctaagacaagagctggtggtgctctgccacctccaccat
cccagcttagtatctctgctggcggctgggattcgtcctcgaatgttggtgatggagttg
gcctccaaggggtccctggatcgcctgcttcagcaagacaaagccagcctcaccaggacg
ctgcagcacaggatcgcgctccacgtggctgatggcttgagatacctccactcagccatg
attatataccgtgacttgaagccccacaacgtgctgctcttcaccctgtatcccaacgct
gccatcattgccaagattgccgactacgggattgcccagtactgctgtagaatggggata
aaaacgtccgagggcacaccagggttccgtgcacctgaagttgctagaggaaatgttatt
tataaccagcaagctgatgtatattcatttggtttgcttctctatgacattttgacaact
ggaggcagaatagcagagggtttgaagtttccaaatgagtttgatgaattggcaatacaa
ggaaaattacctgatccagttaaagaatatggttgtgccccatggcccatggttgagaag
ttaattaaaaagtgtttgaaagaaaatcctcaagaaagacctacttctgcccaggtcttt
gacattttgaattcagctgagttaatctgtctcatgagacgtatatcaatacctaaaaac
ttcactgttgaatgcatggttgcttcaaatcatattagcaagaatgcaagcatttggctg
ggctgtgggcacactgacaaaggactgctctcacttcttgacttaaatactgaaagatac
atttctgaggaagttactgacagcagaatactgtgcctggccttggtgcatcttccagtg
gaaaaggaaagctggatcgtgtctggaacccagtctggcacgctcctcgccatcaatact
gaagacgagagaaagaggcatacccttgaaaagatgactgattctgttacttgcttgtac
tgccattccttctccaggcaaagcaagcaaaaaaatttcctcttagtgggaactgctgat
ggcaacttagcgatttttgaaggtaaaactgttaagtgtaaaggagctgcccctttgaag
atactcaatataggaaatgtcagcacccccctgatgtgtctgagtgaatctatgaattct
actgaaaaaaacatcatgtggggaggatgtggtacaaaaattttttcattttctgatgat
ttcaccattcagaaactcattgagagcaggacaaatcagctgttttcttatgcatcttac
agtgattccaacatcatagcagtggtggtagacacggttctttatgttgctaagaaaaat
agcccatttgtggaagtgtgggacaagaagactgaaaaactctgtgaactgatagactgt
gtgcactttttaaaggaggaactggtaaaagtgaacaaggaatcaaaacacaaaatgtct
tattctgggagagtgaaaactctcagcctgcaaaagaacactgctctctggataggaact
ggagggggccacatcttactccttgatctctcaacgcgtcgaattatacgtataattcac
aacttttgtgattctgttagagtcatgatgacagcacagctaggaaaccttaaaaatgtc
atgctggttctgggatataatcggaaaaatactgaaggtatgcaacaccaaaaagaaata
cagtcttgcttgtctgtttgggacatcaatctgccacatgaagtgcaaaatttagagaaa
catattgaagtgagaaaagaattagctgaaaaaatgagaagaatatctgttgaataa
DBGET
integrated database retrieval system
