Camelus dromedarius (Arabian camel): 105090026 Help Entry 105090026         CDS       T04642                                  Symbol RYR3 Name (RefSeq) ryanodine receptor 3 isoform X1   KO K04963   ryanodine receptor 3 Organism cdk  Camelus dromedarius (Arabian camel) Pathway cdk04020   Calcium signaling pathway cdk04371   Apelin signaling pathway cdk04713   Circadian entrainment cdk04921   Oxytocin signaling pathway cdk04970   Salivary secretion cdk05010   Alzheimer disease cdk05012   Parkinson disease cdk05020   Prion disease cdk05022   Pathways of neurodegeneration - multiple diseases Brite KEGG Orthology (KO) [BR:cdk00001]  09130 Environmental Information Processing   09132 Signal transduction    04371 Apelin signaling pathway     105090026 (RYR3)    04020 Calcium signaling pathway     105090026 (RYR3)  09150 Organismal Systems   09152 Endocrine system    04921 Oxytocin signaling pathway     105090026 (RYR3)   09154 Digestive system    04970 Salivary secretion     105090026 (RYR3)   09159 Environmental adaptation    04713 Circadian entrainment     105090026 (RYR3)  09160 Human Diseases   09164 Neurodegenerative disease    05010 Alzheimer disease     105090026 (RYR3)    05012 Parkinson disease     105090026 (RYR3)    05020 Prion disease     105090026 (RYR3)    05022 Pathways of neurodegeneration - multiple diseases     105090026 (RYR3)  09180 Brite Hierarchies   09183 Protein families: signaling and cellular processes    04040 Ion channels [BR:cdk04040]     105090026 (RYR3) Ion channels [BR:cdk04040]  Voltage-gated cation channels   Ryanodine receptor    105090026 (RYR3) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  RYDR_Jsol RYDR_ITPR RyR RR_TM4-6 MIR SPRY Ins145_P3_rec RIH_assoc Ion_trans EF-hand_7 EF-hand_1 EF-hand_6 EF-hand_8 EF-hand_5 Motif Other DBs NCBI-GeneID:  105090026 NCBI-ProteinID:  XP_031309212 LinkDB All DBs Position 6:28931278..29443806 Genome browser AA seq 4879 aa AA seqDB search MAEGGEGGEDEIQFLRTEDEVVLQCIANVHKEQRKFCLAAEGLGNRLCFLEPTSEAKFVP PDLCVCNFVLEQSLSVRALQEMLANTGENGGEGFQRKAAQGGGHRTLLYGHAILLRHSFS GMYLTCLTTSRSQTDKLAFDVGLREHATGEACWWTIHPASKQRSEGEKVRIGDDLILVSV SSERYLHLSISNGNIQVDASFMQTLWNVHPTCSGSSVEEGYLLGGHVVRLFHGHDECLTI PSTDQNDSQHRRVFYEAGGAGTRARSLWRVEPLRISWSGSNIRWGQAFRLRHLTTGHYLA LTEDQGLILQDRGKSDTKSTAFSFRASKEIKEKLDSSHKRDIEGMGVPEIKYGDSVCFVQ HVASGLWVTYKAQDAKTSRLGPLKRKVILHQEGHMDDGLTLQRCQQEESQAARIIRNTTA LFSQFVSGNNRTTAPVTLPIEEVLQTLQDLIAYFQPPEEEMQHEDKQNKLRSLKNRQNLF KEEGMLALVLNCIDRLNIYNSIAHFAGIAREESGMAWKEILNLLYKLLAALIRGNRNNCA QFSNNLDWLISKLDRLESSSGILEVLHCILIESPEALNLIAEGHIKSIISLLDKHGRNHK VLDVLCSLCLCNGVAVRANQNLICDNLLPRRNLLLQTRLINDVTSIRPNIFLGVAEGSAQ YKKWYFELIIDQVDPFLTAEPTHLRVGWASSSGYAPYPGGGEGWGGNGVGDDLYSYGFDG LHLWSGRIPRAVASVNQHLLRSDDVVSCCLDLGAPSISFRINGQPVQGMFENFNTDGLFF PVVSFSAGVKVRFLMGGRHGEFKFLPPSGYAPCYEALLPKEKMRLEPVKEYKRDAEGVRD LLGTTQFLSQASFIPCPIDTSQVVLPPHLEKVRDKLAENIHELWGMNKIELGWTFGKIRD DNKRQHPCLVEFSKLPETEKNYNLQMSTETLKTLLALGCHIAHVNPAAEEDLKKVKLPKN YMMSNGYKPAPLDLSDVKLLPPQEILVDKLAENAHNVWAKDRLKQGWTYGIQQDLKNKRN PRLVPYALLDERTKKSNRDSLREAVRTFVGYGYNIEPSDQELADPAVEKVSIDKIRFFRV ERSYAVRSGKWYFEFEVVTGGDMRVGWARPGCRPDVELGADDQAFVFEGSRGQRWHQGSG YFGRTWQPGDVVGCMINLDDASMIFTLNGELLITNKGSELAFADYEIHNGFVPICSLGLS QIGRMNLGTDASTFKFYTMCGLQEGFEPFAVNMNRDVAMWFSKRLPTFVNVPKDHPQIEV VRIDGTMDSPPCLKVTHKTFGTQNSNATMIYCRLSMPIECHSSFSHSPCLDSEAFQKRKQ MQEILSHTTTQCYYAIRIFAGQDPSCVWVGWVTPDYHLYSEKFDLSKNCTVTVTLGDERG RVHESVKRSNCYMVWGGDVVATSQRASRSNVDLEIGCLVDLAMGMLSFSANGRELGTCYQ VEPNTKVFPAVFLQPTSTSLFQFELGNLKNAMPLSAAIFKSEEKNPVPQCPPRLDVQTIQ PVLWSRMPNSFLKVETERVSERHGWVVQCLEPLQMMALHIPEENRCVDILELCEQEDLMQ FHYHTLRLYSAVCALGNSRVAYALCSHVDLSQLFYAIDNKYLPGLLRSGFYDLLISIHLA SAKERKLMMKNEYIIPITGTTRKIRLYPDASKRHGLPGVGPRTCLKPGFRFSTPCFVVTS EEHQKQSPEIPLELLKTKALSMLTEAVQCSGAHIRDPVGGSVEFQFVPVLKLIGTLLVMG VFDDEDVRQILLLIDPSVFGEHSAEMEEGAEKEEVTQVEEKAVEAGEKASKEAGKEAPVK GLLQTRLPESVKLQMCELLSYLCDCELQHRVEAIVAFGDIYVSKLQANQKFRYNELMQAL NMSAALTARKTREFRSPPQEQINMLLNFQLGENCPCPEEIREELYDFHEDLLIHCGVPLE EEEEEEEDASWTGRFRALVYKIKGLPKLEKEQPTEEEERSPTTLKELVSQTMIRWAQEDQ IQDAELVRMMFTLLRRQYDSIGELLQALRKTYTISQASVSDTIGLLAALGQIRCLLSVRM GKEEELLMINGLGDIMNNKVFYQHPNLMRVLGMHETVMEVMVNVLGTEKSQIAFPKMVAS CCRFLCYFCRISRQNQKAMFEHLSYLLENSSVGLASPSMRGSTPLDVAASSVMDNNELAL GLEEPDLEKVVTYLAGCGLQSCPMLLAKGYPDVGWNPIEGERYLSFLRFAVFVNSESVEE NASVVVKLLIRRPECFGPALRGEGGNGLLAAMQGAIKISENPALDLPSQVYKREVSTEGD GDEEEIVHMGNAIMSFYSALIDLLGRCAPEMHLIQTGKGEAIRIRSILRSLVPTEDLVGI ISIPLKLPSLNKDGSIYEPDMAANFCPDHKAPMVLFLDRVYGIKDQAFLLHLLEVGFLPD LRASASLDTVALSTTEAALALNRYLCAAVLPLLTRCAPLFAGTEHYTSLIDSTLQTIYRL SKGRSLTKAQRDTIEQCLLAICNHLRPSMLQQLLRRLVFDVPQLNEYCKMPLKLLTNHYE QCWKYYCLPSGWGSYGLAVEEELHLTEKLFWGIFDSLSHKRYDSDLFRMALPCLSAIAGA LPPDYLDTRMSATLEKQVSVDADGNFDPKPINTVNFSLPEKLEYIVTKYAEHSHDKWACD KSQNGWKYGISLDENVKTHPLIRPFKTLTEKEKEIYRWPARESLKTMLAVGWTVERTKEG EALVQQRENEKLRSVSQASQGNSYSPTPLDLSNVVLSRELQGMVEVVAENYHNIWAKKKK LELESKGGGSHPLLVPYDTLTAKEKFRDREKAQDLFKFLQVNGVVVSRGMKDMELDASSM EKRFAYKFLKKILKYVDSAQEFIAHLEAIVSSGKTEKPPHDQEIKFFAKVLLPLVDQYFT NHRLYFLSSPLKPLSSSGYASHKEKEMVASLFCKLAALVRHRISLFGSDSATMVSCLHIL AQTLDTRTVVKSGSELAKAGLRAFFENAAEDLEKTSENLKLGKFTHSRTQIKGVSQNINY TTVALLPILTSIFEHVAQHQFGVDLLLGDVQISCYHILCSLYSLGTGKNIYVERQRPALG ECLASLAAAIPVAFLEPTLNRYNPLSVFNTKTPRERAILGMPDTVEEMCPDIPQLEGLMK EINDLAESGARYTEMPHVIEVILPMLCNYLSYWWERGPEHLPPSTGPWCTKVTSEHLSVV LGNILKIINNNLGIDEASWMKRIAVFAQPIISKARPDLLRSHFIPTLEKLKKKALKTVQE EEQLKADSKGDTQEAELLILDEFAILCRDLYAFYPMLIRYVDNNRSNWLKSPDADSDQLF RMVAEVFILWCKSHNFKREEQNFVIQNEINNLAFLTGDSKSKMSKAMQVKSGGQDQERKK TKRRGDLYSIQTSLIVAALKKMLPIGLNMCTPGDQELISLAKSRYSYKDTDEEVKEHLRN NLHLQEKSDDPAVKWQLNLYKDVLKSEEPSNPEKTVERVQRISAAVFHLEQVEQPLRSKK AVWHKLLSKQRKRAVVACFRMAPLYNLPRHRSINLFLHGYQRFWIETEEYSFEEKLVQDL AKSPKLEEEEEEETEKQPDPLHQIILHFSRNALTERSKLENDPLYTSYSSMMAKSCQSGE DEEEEEDKEKTFEEKETEKQKTLYQQARLHERGAAEMVLQMISASKGEMSPMVVETLKLG IAILNGGNASVQQKMLDYLKEKKDAGFFQSLSGLMQSCSVLDLNAFERQNKAEGLGMVTE EGTLIVRERGEKVLQNDEFTRDLFRFLQLLCEGHNSDFQNFLRTQMGNTTTVNVIISTVD YLLRLQESISDFYWYYSGKDIIDESGQHNFSKALAVTKQIFNSLTEYIQGPCIGNQQSLA HSRLWDAVVGFLHVFANMQMKLSQDSSQIELLKELLDLLQDMVVMLLSLLEGNVVNGTIG KQMVDTLVESSANVEMILKFFDMFLKLKDLTSSDTFKEYDPDGKGIISKKEFQKAMEGQK QYTQSEIDFLLSCAEADENDMFNYIDFVDRFHEPAKDIGFNVAVLLTNLSEHMPNDSRLK CLLEPAESVLNYFEPYLGRIEIMGGAKKIERVYFEISESSRTQWEKPQVKESKRQFIFDV VNEGGEQEKMELFVNFCEDTIFEMQLASQISESDSADRPEEEEEDEEDAPYTLEMEGEEE DDKSFECASAFAVACASVRRNVANFLRRATLKNLRKQYRKVKKMSLKELVKVFFSFFWML IMGFFQLVFAILGGIFQILWSTVFGGGLVEGAKNIRVTKILGDMPDPTQFGIHDDALEAE RAEGPELGITTELIHFVKGEKGNADVMSDLFGFHPKKEGGVKHGPEVGLGDLSEIIGKDE PPTLESTIRRKRKAQAAERKTAHEAEGRVESEKAGIEDGEKEDAAKEEEQPEALWADVTK RKKRRCGQKAEKPEAFMANFFKGLEIYQTKLLHYLARNFYNLRFLALFVAFAINFILLFY KVTEEPLEEETEDIANLWNSFNDEDEEEAMVFFVLQESTGYMAPALRALAVIHTIISLVC VVGYYCLKVPLVVFKREKEIARKLEFDGLYITEQPSEDDIKGQWDRLVINTPSFPNNYWD KFVKRKVINKYGDLYGAERIAELLGLDKNALDFSPVEETKAEAASLVSWLSSIDMKYHIW KLGVVFTDNSFLYLAWYTTMSVLGHYNNFFFAAHLLDIAMGFKTLRTILSSVTHNGKQLV LTVGLLAVVVYLYTVVAFNFFRKFYNKSEDDEEPDMKCDDMMTCYLFHMYVGVRAGGGIG DEIEDPAGDPYEMYRIVFDITFFFFVIVILLAIIQGLIIDAFGELRDQQEQVREDMETKC FICGIGNDYFDTTPHGFETHTLQEHNLANYLFFLMYLINKDETEHTGQESYVWKMYQERC WDFFPAGDCFRKQYEDQLG NT seq 14640 nt NT seq  +upstreamnt  +downstreamnt atggccgaagggggagaaggaggcgaggacgagatccagtttctgcggactgaggatgaa gtggtcctccagtgcatcgcgaacgttcacaaggagcagaggaagttctgcctggcagcc gagggactagggaatcgcctgtgcttcttggaacccacatcagaagccaagtttgttcct ccagatctctgcgtctgcaattttgtgctggagcagtccctctctgtcagagccctgcag gaaatgcttgccaacacaggtgaaaatggcggcgaagggtttcaaaggaaggcagcacaa ggcggtggccacaggaccctgctgtacggccacgcgattctcctgcggcactctttcagc ggaatgtatctaacatgcttgactacatcgagatcccagacagataaacttgcctttgat gtaggtctacgcgaacatgccacaggtgaagcctgttggtggaccatacatcctgcttcc aagcagaggtctgagggagaaaaggttcgaattggcgatgacctcatccttgtcagcgtg tcctctgaaagataccttcatctctcaatatccaatggtaacatacaagtggatgcctcc ttcatgcaaaccctctggaacgtacatccgacgtgctcaggaagtagcgtagaagaagga tacctgcttggtgggcacgtagtacgtcttttccatggtcatgatgagtgtttgacgata ccatctacagaccagaatgattcccagcacaggagggtattctatgaagccgggggagct ggcacgagagctagatctctgtggagagtggaaccccttcggataagctggagtggcagt aacatcagatggggccaggctttccgacttcggcacctcaccacaggccactacctggcc ttgacagaggaccaaggccttatactgcaagaccggggaaaatcagacaccaagtccaca gccttctctttccgggcatcaaaggaaatcaaggagaaattggattccagccacaagcga gatatagaaggcatgggagtcccggaaatcaagtatggagattccgtctgctttgtccag cacgtagccagtggtctgtgggtgacctacaaagcacaggatgccaagacatcccgcctt ggacctctgaaaagaaaggtcatactccatcaggaaggccacatggatgacggcttaacc ctgcagagatgccagcaggaggagtcccaggctgctcggatcatacggaatacgacagcc ttgttcagccagttcgtcagtggaaacaatcgcacaactgcccctgtcaccctgccgata gaagaggtcctacagaccttgcaggacttgattgcctacttccagcccccagaggaggag atgcagcatgaagacaagcagaacaagctccgctcactcaaaaacagacagaatcttttc aaggaagagggaatgttggcccttgtgttaaactgcattgatcgcttaaatatctacaat agcatcgctcacttcgcagggattgccagggaggagagtggcatggcctggaaagaaatt ctgaacctcctgtacaaactgctggctgctctcatccgtggaaacagaaacaattgcgct caattctccaataaccttgattggctaatcagcaaactggacagactagaatcttcctca ggtatcttggaagttctgcactgcatcctgatcgaaagcccagaagccttaaatctgata gcagagggtcacatcaagtctatcatctccctgttggataagcacgggcggaatcacaag gtgctggatgtgctgtgctccctctgtctctgcaatggggtcgcagtgagagccaaccag aatctgatctgcgacaacttgctgccccggagaaatctgctcctgcagacgcggctgatt aacgatgtgacaagtattcggccaaacatcttcctgggagtcgctgagggctcagcgcag tacaagaagtggtacttcgagctgatcatcgaccaggtggaccccttcctcacagcagag cccacacacctgcgggtgggctgggcctcttcctcaggctatgctccgtaccccggaggt ggggaaggatggggaggcaacggtgttggcgacgacctgtactcctatggctttgatggg ctgcacctttggtcaggccgcataccccgagccgtggcctccgtcaaccagcacctcctc cggtcggacgacgtggtgagctgctgcctggaccttggagcgcccagcatctctttccgc atcaacgggcagcctgtccaggggatgtttgagaacttcaacacagatgggctcttcttc cctgtggtgagcttttcagcaggtgtcaaagtacgtttcctgatgggtggacgtcatgga gaatttaagtttctgcctccctccggctatgccccttgctatgaagccttacttccaaaa gaaaagatgagattggagcctgtcaaagagtataaacgagatgccgaaggcgtcagagat ctgttgggtaccacccagtttctgtcccaagcctctttcatcccgtgccccatagacacc agccaggtggttttgccgcctcacctagagaaggtccgggacaagctggcagaaaacatc cacgagctttggggaatgaataagatagagctgggctggacttttggcaagatacgggat gacaataaaagacaacacccctgccttgtcgagttttcaaagctgcccgaaactgagaag aattataacctacaaatgtcaaccgaaactctaaagaccctcctggccctggggtgtcac atcgctcacgttaacccggctgccgaagaggatctaaagaaggtcaaattgcccaaaaac tacatgatgtccaacggctataagcctgcccctttggatttgtctgatgtgaagctgcta cctcctcaagaaattctagtggataagcttgcagaaaatgcacacaacgtttgggcaaaa gacaggctaaaacagggatggacctatggcattcaacaggatttaaagaacaaaagaaac ccccggctggtaccatacgcgctactggatgagcgtaccaagaagtccaacagagacagc cttcgtgaagctgttcggacgtttgtcggttatggctataacattgagccatcagaccaa gaactggccgacccagctgtggagaaagtcagcatagacaagatccggtttttccgagta gagcggtcatatgccgtgagatctggaaagtggtattttgagtttgaggtggtgaccgga ggagacatgcgcgtcggctgggccaggccaggctgtcggccggacgttgagctgggggcc gatgaccaagcctttgtgtttgaaggcagcaggggccagcgctggcatcaagggagtggg tattttggacggacctggcaaccaggagacgtggttggatgtatgattaacctggatgat gcttcaatgatcttcacactgaacggggagctgctgatcaccaacaaaggctctgaactt gccttcgctgactatgagattcacaacggctttgtgcccatctgctccctgggactctct cagatcgggcgcatgaatctcgggacagatgccagcaccttcaagttttataccatgtgt ggcctccaagagggctttgagccttttgctgtcaacatgaaccgagacgtggccatgtgg ttcagcaagcggctcccgacatttgtcaacgtgccaaaggaccatccacagatagaggtc gtgaggatcgacggcaccatggacagccctccgtgtctcaaggtgacccacaagacgttc ggcacccaaaacagcaatgccaccatgatctactgccgcctgagcatgcccatcgagtgc cactcttccttcagtcacagcccctgtctggacagtgaggctttccagaaaaggaaacag atgcaagaaatactctctcacacaacaacacagtgctactatgcaatccgcatctttgct gggcaggacccttcctgcgtctgggtcggatgggtgactccggactatcacttgtatagt gagaagttcgacctgagtaaaaactgtaccgtgactgttactctgggggatgaaagaggc cgagtccatgaaagtgtgaagcgcagcaactgctacatggtctggggtggggacgttgtg gccacatcccaaagggcgagtcgcagcaacgtggacctggagatcggctgcctcgtggac ctggccatgggcatgttgtccttctcggccaacgggagggaactcggcacctgctaccag gtggagcccaataccaaagtgtttccagcggtcttcctgcaacctacaagcacctctttg tttcagtttgaacttgggaacctgaagaacgcgatgcccctgtctgcggccatatttaag agtgaagagaagaacccagtcccacagtgcccgccccggctggacgtccaaaccatccag cccgtgctctggagccgcatgcccaacagcttcctgaaggtggagacggagcgggtgagc gagcgccacggctgggtggtgcagtgcctggagcccctgcagatgatggcgctccacatc ccggaggagaacaggtgtgtggacatcctggagctatgtgagcaggaggacctgatgcag ttccactaccacacgctgagactctacagcgccgtgtgtgccctgggaaacagccgggtg gcctacgccctgtgcagccacgtggacctctcccagctcttctacgccattgacaacaag tacctccccggcctcctgcgctctggcttctatgacctgctcatcagcatccacctggcc agcgcgaaggagaggaagctgatgatgaagaatgagtacatcatccccatcaccggcacc acccggaaaatccgcctgtaccccgacgcgtccaagaggcatgggctccctggggtgggc ccaagaacgtgcctcaagccagggttcaggttctccaccccttgtttcgtcgtgaccagc gaggagcaccagaagcagagccctgagatccccttggagctcctcaagacgaaggcgctg agcatgctgacggaggccgtgcagtgcagcggggctcacatccgggaccccgtcggcggg tctgtggagttccagtttgtgcccgtgctgaaactcattggaactctgttggtcatgggg gtatttgacgatgaagacgttcggcagatcctcctcctcatcgacccctctgtgtttggg gaacacagtgcagagatggaggagggggcagagaaggaggaggtgacccaggtggaggag aaggctgtggaggctggggaaaaggccagcaaggaggccggcaaggaggctcccgtcaaa ggcttgctgcagacccggttaccggagtctgtcaagctgcagatgtgtgagctcctcagc tatctctgtgactgtgagctgcagcaccgagtggaggccattgtggcatttggcgacatt tatgtctctaagctccaggcaaatcagaagttccgctacaatgagctcatgcaagccctg aacatgtctgcagccctgaccgcccggaagaccagggagttccgctcacccccgcaggag cagatcaacatgcttcttaactttcaactcggggagaactgcccgtgcccagaggagatc cgggaggagctctatgacttccacgaggaccttctcattcactgtggggttcccctggag gaagaggaagaagaggaggaagacgcctcctggacaggaagattccgtgccctggtgtat aaaatcaaaggccttcccaagctggagaaggagcagccaacggaggaagaggagagaagc cctacgacgctgaaggagcttgtctcccagaccatgatccgctgggcgcaggaggaccag atccaggacgcggagctggtccggatgatgttcacactcctgcggaggcagtacgacagc atcggggagctactgcaggctctgaggaagacctacaccatcagccaggcctccgtgagc gacaccattggcctgctggctgccctgggccagattcgctgcctgctcagcgtccggatg ggcaaggaggaggagctgctcatgatcaacggtctgggagacataatgaacaacaaggtg ttttaccagcaccccaacctcatgcgcgtcctcggcatgcacgaaacggtgatggaggtg atggtgaacgtgctgggtacagagaagtctcagatcgcctttccaaagatggttgctagc tgttgccgcttcctgtgctatttctgccgaattagccgacaaaaccagaaggccatgttt gagcatctaagttacctgctggagaatagcagtgttggcctagcctccccgtcgatgaga gggtccaccccgctggatgtggcagcttcctccgtgatggacaacaacgagctggcgctg ggcttagaggagccagacctcgagaaggtggtgacctacttggcaggctgcggcctgcag agctgccccatgcttctggccaaaggatacccggacgtcggctggaaccccattgaaggg gagcgctacctgtccttcctgaggtttgccgtcttcgtgaacagtgaaagtgtggaggaa aatgctagtgtcgtggtcaaactgctcatcagacgccccgagtgcttcggcccagccctg cggggtgaaggaggaaacggtctgctggcagccatgcaaggcgccattaagatctccgag aacccagccctcgacctcccctcgcaggtctacaagagagaagtcagcacagagggcgat ggagatgaagaggagattgtgcacatgggcaatgcaattatgtcattttactcggctcta atagacctgttgggccgctgtgctcctgaaatgcaccttatccagacaggaaaaggggaa gccatccggatcaggtccatcctgcgctccctggtccccactgaggacttggtcgggatc atcagcatccccttgaaactgccctccctgaacaaagacgggtcaatctacgagccggat atggcggccaacttctgccccgaccacaaggcacccatggtgctgttcttggaccgcgtt tacggcatcaaggaccaggctttcctgctccacttgctggaggttggatttttacctgac ttaagagcctctgcctctctagatacggttgccctgagcaccacagaggcggcgctggcg ctgaacaggtacctctgcgcggccgtgctcccgctgctcacacggtgcgccccgctcttt gccggaacagagcactacacctctttgatcgattctacgctgcagaccatctacaggctt tccaagggccgttccctcaccaaagctcagagggacaccatcgagcaatgcttgcttgcc atctgcaatcacttgaggccttccatgttacagcagctcctgcgacgtctagtttttgat gtgccacaactcaacgaatactgcaaaatgcctctgaagcttctgacaaatcactacgag cagtgctggaagtattactgtctgccttcgggctgggggagctacggtctggctgtggag gaagagctgcacctgacagagaagctcttctgggggatttttgactccctgtcccataag aggtatgactcagatcttttccggatggccctgccttgtctcagtgctattgccggggcc ttgccaccagattacttagataccagaatgtcagccacgttggagaagcaggtctcagtg gatgctgatggcaactttgaccccaaacccatcaacaccgtgaatttctccctgcctgaa aaattggaatacatagtcaccaagtatgcggagcattcacatgataaatgggcctgtgac aagagtcagaatggatggaaatacggcatttccctggacgaaaatgtgaagacacatcca ttgatcaggcctttcaagacattaacagagaaggagaaggaaatttatcgctggcctgcc agggagtccctgaaaacgatgctggctgtgggctggaccgtggagaggaccaaagaggga gaagccctagttcaacagcgggaaaatgagaagctacgaagcgtgtcccaggccagccag ggcaacagctacagccccactcccctggacctctccaacgtcgtgctctccagagagctc caggggatggtggaggtggtagctgagaactatcacaatatctgggccaagaagaagaag ctggaactggagagcaaaggtggcggcagtcaccctcttttggtaccatatgacacgctg actgccaaggaaaagttcagggaccgagagaaggcgcaggacctgtttaaattcctccaa gtgaatggcgtcgtggtttctagaggtatgaaggatatggaactggacgcctcctccatg gaaaagaggtttgcctataagtttttgaagaagatcctgaaatatgttgattctgctcaa gagtttattgcccatttggaagccattgtcagcagtgggaaaactgaaaagcctccccat gaccaggagatcaaattctttgccaaagttctcctcccgctggttgaccagtacttcacc aatcaccgcctctactttctctcgtcccctctgaagccccttagcagcagcgggtatgcc tcccataaggagaaagaaatggtggccagcctgttctgcaaactcgctgctcttgttcgg cacaggatttccctcttcgggagcgattctgctacaatggtgagctgtcttcacatctta gcacagacacttgacacaaggactgtcgtgaagtcaggctcagagctggcaaaggctggg ctacgagcattctttgaaaacgccgcagaagatttggagaagacttcggaaaacctgaag cttgggaagtttacccattccaggacgcagatcaaaggcgtttcccagaacattaactac accacagtggctctgctccccatcctgacatccatctttgagcacgtcgctcagcatcag ttcggggtggacttgctcttgggtgacgtgcagatttcatgctaccacatactgtgcagc ctctactccctcgggacgggcaagaacatctatgttgaaaggcaacgtcctgctcttgga gaatgcctggcctctctggcagccgccataccagtggccttcctggagcccacccttaac cgctacaatccgctctcagtcttcaacaccaaaacccccagggagagggccattctgggg atgccagacacggtggaggagatgtgccccgacatcccccagctggaaggcctgatgaag gaaatcaacgacctggccgagtcgggggcccggtacacggagatgccgcacgtcatcgag gtgatcttgcccatgctctgcaactacctgtcctactggtgggagcggggacctgagcac ctgccccccagcacaggcccctggtgcaccaaggtcacctctgaacacctcagtgtcgtc ctgggcaacattctgaaaatcatcaacaacaacctgggcatcgacgaggcctcgtggatg aagcgcatcgcagtgttcgcccagcccatcatcagcaaagccaggccggacctgctgaga agccacttcatcccgaccctggagaagctgaagaagaaggccctcaagaccgtgcaggag gaggagcagctgaaagccgacagcaaaggggacactcaggaggcggagctcctcatcctg gacgagtttgccatcctctgcagagacctgtacgccttctaccccatgctgatccgctac gtggacaacaacaggtctaactggctcaaaagccctgatgctgactctgaccagctcttc cgcatggtggcagaggtcttcatcctgtggtgcaaatctcacaacttcaagagggaggag caaaattttgtgattcagaatgaaattaataacttggcatttttaactggagacagcaaa agcaagatgtcaaaagccatgcaagtaaagtctggaggacaggaccaggaacggaagaag acaaagcggagaggagacttgtattccatccagacctccctcattgtggctgcactcaag aagatgctacccattggtttgaatatgtgcacccctggcgatcaggagctgatctccctc gcaaaatcacgatacagctataaggatacagatgaagaggtaaaggaacatctgcggaat aacttgcacttgcaggaaaagtctgatgacccagctgtaaagtggcagctgaacctgtac aaagatgtcctgaagagtgaagaaccttccaacccagaaaagacagtggagcgtgtgcag agaatttcagcagctgtcttccacctggagcaggtggaacagcctttgagatccaagaag gcagtctggcacaaactgctgtcaaagcagcggaaacgggcagtggtggcctgtttcagg atggcccctctctacaacctgcccaggcaccgctctattaacctcttcctccatggctat cagagattttggatagaaacagaggagtattcctttgaagagaaactagtacaggatttg gctaaatcccccaagttggaagaggaggaggaggaggagacggaaaagcagccagaccca cttcatcagatcattctccacttcagccgcaatgctctcacggagaggagcaaactggaa aatgaccctttgtacacgtcctactccagcatgatggccaagagttgtcagagtggggag gacgaagaagaggaggaagacaaggaaaaaacatttgaagagaaagaaacggaaaagcag aaaaccctctatcagcaggctcggctgcacgagcgtggagccgcagagatggtccttcag atgatcagcgccagcaaaggtgagatgagccccatggtggttgagacgctgaagctgggg atcgccatcctgaatgggggcaacgccagcgtgcagcagaaaatgctagattacctaaag gagaagaaggatgctgggttctttcaaagcctttctggtcttatgcagtcttgcagtgtc ctcgatttgaatgcatttgagaggcagaataaagctgaaggcctggggatggttactgag gaaggaacactcattgttcgtgagcgtggtgaaaaagtactgcagaatgacgagtttaca cgcgatctctttagattcctgcagctactttgtgaaggacataacagtgacttccagaac ttcctgcggacgcagatgggcaacaccaccaccgtgaacgtcatcatcagcaccgtggac taccttctgcgcctgcaggaatcaatcagtgatttctactggtattactcagggaaggac atcattgatgaatccggacagcacaatttttctaaagctttggcggtcaccaagcagatt ttcaattcgcttacagaatacatccagggcccctgcattgggaaccagcagagcctggcc cacagcaggctgtgggacgcggtggtcggcttcctccacgtgtttgctaacatgcagatg aaactctctcaggattccagtcagatcgagctgctgaaggaactcttggatctccttcag gacatggtggtgatgcttctgtccctcctggaagggaatgtggtaaatggaactattggc aagcagatggttgacaccctggtagagtcctctgccaatgtagaaatgatcttgaaattc tttgacatgttcttgaaacttaaagacttaaccagctcagacactttcaaagaatatgac cctgatggtaaagggatcatctctaaaaaggaattccagaaggccatggaagggcaaaaa cagtacacgcagtcggagattgactttctcctctcgtgcgcagaagctgatgagaatgac atgtttaattacattgattttgtggaccggttccatgagccggccaaggacatagggttt aacgtggcagtgttgttgacaaacctctcagagcatatgccgaatgattctcgccttaag tgtctattggaaccagcagaaagtgtactaaactacttcgaaccatacctcggacgcatt gagatcatgggtggggccaagaaaattgaacgtgtttactttgagatcagcgagtccagt cgaactcagtgggagaagccccaggtgaaggagtcgaagcgacagttcatctttgacgtc gtcaatgaaggcggagagcaggagaagatggaactgttcgtgaacttctgtgaggatacc atctttgagatgcagttagcatctcagatctctgagtcggactcagctgaccggccggaa gaggaggaggaggacgaggaagacgctccttatacgttggagatggagggtgaagaggag gacgacaagtctttcgaatgtgcctctgcatttgccgtggcctgtgcctcggtgaggagg aacgtggccaactttctgaggagggccaccctgaagaacctcaggaagcagtacaggaag gtgaagaagatgagcctcaaggagctggtgaaggtgttcttctctttcttctggatgttg atcatggggttcttccagttggtcttcgccatcttgggaggaatctttcagatcctctgg agcacagtgtttggagggggcctcgtggaaggggccaagaacatccgagtcaccaagatc ctgggtgacatgcctgacccgacccagtttggtatccacgatgatgctctggaggctgag cgggcagaggggcctgagctgggcatcaccacggaactcatacacttcgtcaagggggag aagggcaatgcggatgttatgtcggatctctttggattccaccctaagaaagaaggtggc gtaaagcatgggcccgaagtgggtttgggtgacctctctgagattattggcaaggatgag ccccctacgttagagagtactatacggaggaaaaggaaagcacaggcagcagagaggaaa acagctcatgaagcagaaggaagagtggagtctgagaaggcaggcatagaagatggggag aaagaggatgcagccaaggaagaagagcagcccgaggccctctgggcggacgtgacaaag aggaagaagcgacggtgtggccagaaagctgagaagcccgaagccttcatggccaatttc tttaaagggctggaaatctatcagaccaagttgctgcactacctggccaggaatttctac aacctgaggttccttgctctgtttgtagccttcgctatcaacttcatcctgctcttttac aaggtcaccgaggaacctttagaagaagagacagaggacattgcaaacctgtggaattcc tttaatgatgaggacgaggaagaagcaatggtgttctttgtcctgcaggagagcacgggg tatatggcgccagcactgcgggccctggccgtcatccacaccatcatctctttggtctgc gtggtgggctactactgcctgaaggtccctctggtggtcttcaaaagagaaaaagaaatt gccaggaagctggagtttgatggcctgtatatcaccgaacagccttctgaagatgacatc aaggggcagtgggatcgcctggtgatcaacaccccatcttttcctaataactactgggac aagtttgtcaagagaaaggtgatcaacaaatacggagacctctacggagcggaacgcatt gcagaactgctgggtttggacaaaaatgcccttgactttagcccagtggaagagaccaaa gcagaggcggcctccctggtgtcatggctgagttccatcgacatgaagtaccatatctgg aagctgggagttgtttttaccgacaactccttcctctacctcgcctggtacacgaccatg tcagtcctgggccactacaacaacttcttcttcgctgctcatctgctggacatcgccatg ggcttcaagactctgaggacgatcctgtcgtccgtcactcacaacggcaaacagctggtc ctgactgtcgggctgctggccgtggtggtctatctctacacggtggtggcattcaacttc ttccgcaagttctacaacaaaagcgaggatgacgaggagcccgatatgaagtgtgacgac atgatgacgtgttacctgttccacatgtacgtgggagtgagagctggaggtggcatcggc gatgaaattgaagaccctgccggggacccctacgaaatgtaccgcatcgtctttgacatt accttcttcttcttcgtcatcgtcatcctgctggccatcatccaaggtcttattatcgat gcttttggagagctgagagaccagcaggaacaagtgcgggaggatatggagacaaaatgt ttcatctgcgggattggcaatgactacttcgacacgacccctcatggttttgaaacacac accttacaagagcacaacttagccaactacttgttcttcctgatgtatctgattaataaa gacgaaacagagcatacgggtcaggaatcttacgtctggaagatgtaccaggaaaggtgc tgggatttcttcccggctggcgactgcttccggaaacagtacgaagatcagcttggataa

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