| Entry |
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| Symbol |
IDH2
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| Name |
(RefSeq) isocitrate dehydrogenase [NADP], mitochondrial
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| KO |
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| Organism |
cdk Camelus dromedarius (Arabian camel)
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| Pathway |
| cdk01210 | 2-Oxocarboxylic acid metabolism |
| cdk05230 | Central carbon metabolism in cancer |
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| Module |
| cdk_M00010 | Citrate cycle, first carbon oxidation, oxaloacetate => 2-oxoglutarate |
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| Brite |
KEGG Orthology (KO) [BR:cdk00001]
09100 Metabolism
09101 Carbohydrate metabolism
00020 Citrate cycle (TCA cycle)
105094685 (IDH2)
09106 Metabolism of other amino acids
00480 Glutathione metabolism
105094685 (IDH2)
09140 Cellular Processes
09141 Transport and catabolism
04146 Peroxisome
105094685 (IDH2)
09160 Human Diseases
09161 Cancer: overview
05230 Central carbon metabolism in cancer
105094685 (IDH2)
Enzymes [BR:cdk01000]
1. Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.1.1 With NAD+ or NADP+ as acceptor
1.1.1.42 isocitrate dehydrogenase (NADP+)
105094685 (IDH2)
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| SSDB |
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| Motif |
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| Other DBs |
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| LinkDB |
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| Position |
27:complement(17181917..17196400)
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| AA seq |
452 aa
MAGYLRVVRSLCRASGSGPAWAPAALTAPNLQEQPRRHYADKRIKVAKPVVEMDGDEMTR
IIWQFIKEKLILPHVDVQLKYFDLGLPNRDQTNDQVTIDSALATQKYSVAVKCATITPDE
ARVEEFKLKKMWKSPNGTIRNILGGTVFREPIICKNIPRLVPGWTKPITIGRHAHGDQYK
ATDFVADRAGTFKVVFTPKDGSGAREWEVYNFPAGGVGMGMYNTDESISGFAHSCFQYAI
RKKWPLYMSTKNTILKAYDGRFKDIFQEIFEKHYKTEFDKNKIWYEHRLIDDMVAQVLKS
SGGFVWACKNYDGDVQSDILAQGFGSLGLMTSVLVCPDGKTIEAEAAHGTVTRHYREHQK
GRPTSTNPIASIFAWTRGLEHRGKLDGNQDLMRFAQTLEKVCVETVESGAMTKDLAGCIH
GLSNVKLNEHFLNTSDFLDTIKNNLDKALGQQ |
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| NT seq |
1359 nt +upstreamnt +downstreamnt
atggctggttacctgcgggtcgtacgctcgctctgcagagcctccggctccgggccggcc
tgggcaccggcagccctgacagcccccaacttgcaagagcagccgcggcgccactatgct
gacaagaggatcaaggtggcgaagccagtggtggagatggatggcgatgagatgacccgt
atcatctggcagttcatcaaggagaagctcatcctgccccacgtggacgtccagctcaag
tattttgacctggggcttccaaaccgggaccagaccaatgatcaggtcaccatcgactca
gcgttggccacccagaagtacagtgtggctgtcaagtgtgccaccatcacccccgatgag
gcccgtgtggaagagttcaagctgaagaagatgtggaagagtcccaatggaaccatccgg
aacatccttggggggactgtcttccgggagcccatcatctgtaaaaacatcccacgcctc
gtgcctggctggaccaagcccatcaccattggcaggcacgcccacggcgaccagtacaag
gccacagacttcgtggctgaccgggccggcacgttcaaggtggtcttcaccccgaaggac
ggcagcggcgctagggagtgggaggtgtacaacttccctgctggcggcgtgggcatgggc
atgtataacacggacgagtccatctcgggttttgcgcacagctgcttccaatatgccatc
cggaagaagtggccgctgtacatgagcaccaagaacaccattctgaaagcctacgacggg
cgcttcaaggacatcttccaggagatctttgagaagcactataagaccgaattcgacaag
aacaagatctggtacgagcaccggctcattgatgacatggtggctcaggtcctcaagtct
tcaggtggctttgtgtgggcctgcaagaactatgacggagacgtgcagtcagacatcctg
gcccagggctttggttcccttggcctgatgacgtccgtgctggtctgcccggatgggaag
accattgaggctgaggctgctcatgggactgtcactcgccactatcgggagcaccagaag
ggccggcctaccagcaccaaccccattgccagcatctttgcctggacacgtggcctagag
caccggggaaagttggacggaaaccaagatctcatgaggtttgcccagaccctggagaag
gtgtgtgtcgagacagtggagagtggagccatgaccaaggacctggcaggctgcatccac
ggcctcagcaatgtgaagctgaatgagcacttcctgaacacctcggacttcctggacacc
atcaagaacaacctggacaaagctctgggccagcagtag |
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