Camelus dromedarius (Arabian camel): 105098309
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Entry
105098309 CDS
T04642
Symbol
SHMT2
Name
(RefSeq) serine hydroxymethyltransferase, mitochondrial isoform X1
KO
K00600
glycine hydroxymethyltransferase [EC:
2.1.2.1
]
Organism
cdk
Camelus dromedarius (Arabian camel)
Pathway
cdk00260
Glycine, serine and threonine metabolism
cdk00630
Glyoxylate and dicarboxylate metabolism
cdk00670
One carbon pool by folate
cdk01100
Metabolic pathways
cdk01200
Carbon metabolism
cdk01230
Biosynthesis of amino acids
cdk01240
Biosynthesis of cofactors
cdk01523
Antifolate resistance
cdk04981
Folate transport and metabolism
Module
cdk_M00141
C1-unit interconversion, eukaryotes
Brite
KEGG Orthology (KO) [BR:
cdk00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00630 Glyoxylate and dicarboxylate metabolism
105098309 (SHMT2)
09105 Amino acid metabolism
00260 Glycine, serine and threonine metabolism
105098309 (SHMT2)
09108 Metabolism of cofactors and vitamins
00670 One carbon pool by folate
105098309 (SHMT2)
09150 Organismal Systems
09154 Digestive system
04981 Folate transport and metabolism
105098309 (SHMT2)
09160 Human Diseases
09176 Drug resistance: antineoplastic
01523 Antifolate resistance
105098309 (SHMT2)
Enzymes [BR:
cdk01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.2 Hydroxymethyl-, formyl- and related transferases
2.1.2.1 glycine hydroxymethyltransferase
105098309 (SHMT2)
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Gene cluster
GFIT
Motif
Pfam:
SHMT
Aminotran_1_2
Motif
Other DBs
NCBI-GeneID:
105098309
NCBI-ProteinID:
XP_031318123
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All DBs
Position
12:616205..623038
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AA seq
512 aa
AA seq
DB search
MLPFSLFWATRPLQRCGQLVGMVRRCQHSEAAQTPTGEATGGWSGQESLSDSDPEMWELL
RREKDRQCRGLELIASENFCSRAALEALGSCLNNKYSEGYPGKRYYGGAEVVDEIELLCQ
RRALEAFDLDPAQWGVNVQPYSGSPANLAAYTALLQPHDRIMGLDLPDGGHLTHGYMSDV
KRISATSIFFESMPYKLNPQTGLIDYDQLALTARLFRPRLIIAGTSAYARLIDYARMREV
CDEVKAHLLADMAHISGLVAAKVIPSPFQHADVVTTTTHKTLRGARSGLIFFRKGVRAVD
PKTGQEIPYTFEDRINFAVFPSLQGGPHNHAIAAVAVALKQARTPMFREYSLQVLKNARA
MADALLERGYSLVSGGTDNHLVLVDLRPKGLDGARAERVLELVSITANKNTCPGDRSAIT
PGGLRLGAPALTSRQFREDDFRKVVDFIDEGVNIGLEVKRRTALAPEAPPTAHPATPTPP
CLGSKIEVPKGCQRWRRQRRQQSHVAMVTRPV
NT seq
1539 nt
NT seq
+upstream
nt +downstream
nt
atgctacctttctctttgttctgggcgactcggcctctgcagagatgtggtcagctggtc
gggatggtcagaaggtgccagcacagcgaagcagcccagactccaactggagaagcaact
gggggctggtcaggccaggagagtctatcagacagtgatcctgaaatgtgggagctactg
cggagagagaaggacaggcaatgtcgtggcctggagctcattgcctcagagaacttctgc
agccgagctgcgctggaggccctggggtcctgtctgaacaacaagtactcggagggttat
cctggcaagagatattacgggggagctgaagtagtggatgaaattgaactgctgtgtcag
cgccgggccttggaggcctttgacctggaccctgcacagtggggagtcaatgtccagccc
tactctgggtccccagccaatctggctgcctacacagctcttctgcagcctcatgaccga
ataatggggctggacctgcctgatgggggccatctcacccatggctatatgtctgatgtc
aagcggatctccgccacttccatcttcttcgagtctatgccctataagctgaatccccag
accggcctcattgactacgaccagctggcactcactgctcggctcttccgaccgagactc
atcatagccggtaccagtgcctatgcgcgcctcattgactacgcccgcatgagagaggtg
tgtgatgaggtcaaggcacacctgctggcagacatggcccacatcagtggcctggtggct
gccaaggtgatcccctcacctttccagcatgcggacgttgtcaccaccaccactcacaag
acccttcgcggggccaggtcaggactcatcttcttccggaagggggtgcgagctgtggac
cccaagactggccaagagatcccttacacatttgaggaccgaatcaactttgctgtgttc
ccatccctgcaggggggaccccacaaccatgccattgctgcagtggctgtggccctaaag
caggcccgcacccccatgttccgggagtactccctgcaggtcctgaagaatgcgcgggcc
atggctgatgccctgctagagcgaggctactcgctggtgtctggtggcactgacaaccac
ctagtgctggtagacctgcggcccaagggccttgatggggctcgagctgagcgggtgctg
gaactcgtatccatcacggccaacaagaacacctgtcctggagatcgaagcgccatcaca
cctgggggcctgcggcttggggccccagctctgacttcaagacagttccgcgaggatgac
ttccggaaagttgtggactttatcgatgaaggcgtcaacattggcttggaagtgaagaga
aggaccgccctggccccagaagcacccccaacagctcacccagccacccccactccaccg
tgcttgggcagcaagatagaggtacccaaaggctgccagcggtggcggcggcagcggagg
cagcagagccacgtcgccatggtaaccaggccggtataa
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