Camelus dromedarius (Arabian camel): 105099540
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Entry
105099540 CDS
T04642
Symbol
GCLC
Name
(RefSeq) glutamate--cysteine ligase catalytic subunit isoform X1
KO
K11204
glutamate---cysteine ligase catalytic subunit [EC:
6.3.2.2
]
Organism
cdk
Camelus dromedarius (Arabian camel)
Pathway
cdk00270
Cysteine and methionine metabolism
cdk00480
Glutathione metabolism
cdk01100
Metabolic pathways
cdk01240
Biosynthesis of cofactors
cdk04216
Ferroptosis
Module
cdk_M00118
Glutathione biosynthesis, glutamate => glutathione
Brite
KEGG Orthology (KO) [BR:
cdk00001
]
09100 Metabolism
09105 Amino acid metabolism
00270 Cysteine and methionine metabolism
105099540 (GCLC)
09106 Metabolism of other amino acids
00480 Glutathione metabolism
105099540 (GCLC)
09140 Cellular Processes
09143 Cell growth and death
04216 Ferroptosis
105099540 (GCLC)
Enzymes [BR:
cdk01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.2 glutamate---cysteine ligase
105099540 (GCLC)
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
GCS
GCS2
Motif
Other DBs
NCBI-GeneID:
105099540
NCBI-ProteinID:
XP_031290386
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All DBs
Position
20
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AA seq
636 aa
AA seq
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MGLLSQGSPLSWEETQRHADHVRRHGILQFLHIYHAVKDRHKDVLKWGDEVEYMLVSFDH
ENKKVQLVLSGEEVLETLQEKGERTNPNHPTLWRPEYGSYMIEGTPGQPYGGTMSEFNTV
EDNMRKRRQEATSLLGDNQAVCTITSFPRLGCPGFTLPEFRPRPVEGGASKSLFFPDEAI
NKHPRFSTLTRNIRHRRGEKVVINVPIFKDKNTPSPFIETFPEDDEAAKAAKPDHIYMDA
MGFGMGNCCLQVTFQACSISEARYLYDQLATICPIVMALSAASPFYRGYVSDIDCRWGVI
SASVDDRTREERGLEPLKNNSYRISKSRYDSIDSYLSECGEKYNDLDLTIDREIYGHLLQ
EGIDHLLAQHVAHLFIRDPLTLFEEKIHLDDANESDHFENIQSTNWQTMRFKPPPPNSDI
GWRVEFRPMEVQLTDFENSAYVVFVVLLTRVILSYKLDFLIPLSKVDENMKVAQKRDAVL
RGRFYFRKDICKGGSAVVDGCGKAAGAEPAAEEYALMTIDTIINGKEGVFPGLIPILNSY
LENMEVDVDTRCSILNYLKLIKKRASGELMTVARWMREFIAKHPDYKQDSVITDKINYSL
LLKCNQIANELCECPELLGPAFRKVKYSGSKTDPSN
NT seq
1911 nt
NT seq
+upstream
nt +downstream
nt
atggggctgctgtcccaaggctcaccgctgagctgggaggagacccagcgccacgccgac
cacgtgcggcggcacgggatcctccagttcttgcacatctaccacgccgtcaaggaccgg
cacaaggacgtgctcaagtggggcgacgaggtggagtacatgttggtgtctttcgatcat
gaaaacaaaaaagtccaattggtcctgtctggagaggaggttcttgaaactctgcaagaa
aaaggggaaaggacaaacccaaaccaccctaccctttggagaccagagtacgggagctac
atgatcgaagggacaccgggccagccgtacggggggaccatgtccgagttcaacaccgtg
gaggacaacatgaggaagcgccgccaggaggcgacgtctctgctgggagacaaccaggct
gtctgcacgataacctcatttcccagattaggctgccctgggttcacgctgcccgagttc
aggccccgcccggtcgaaggaggagcttccaagtccctcttctttcccgacgaagcaatc
aacaagcacccacgcttcagcaccctaacaaggaacatccggcacaggaggggagagaaa
gtcgtcatcaatgtcccgatatttaaggacaagaacacgccgtctccgtttatagagacg
tttcccgaggatgacgaggcagcgaaggcggctaagccggaccacatttacatggatgcc
atgggcttcgggatgggcaattgctgtctccaggtaacgttccaagcctgcagcatatct
gaggcccgctacctgtatgatcagttggccactatctgcccaattgttatggctttgagc
gctgcgtctcctttttaccgaggctatgtgtcagacattgattgtcgctggggagtgatt
tctgcgtctgttgatgatagaactcgggaggagagaggactggagccgctgaagaacaat
agctataggattagtaaatcccggtacgactccatcgacagttacttgtccgagtgcggg
gagaagtacaatgacctcgacctgaccatagacagggagatctacggccatctgctgcag
gaaggcatcgatcacctcctggcccagcacgtggctcacctcttcatcagagacccgctg
actctgtttgaggagaaaatacacctggacgatgccaacgagtctgaccatttcgagaat
attcagtccacaaattggcagacgatgagatttaagcctcctcccccaaactccgacatt
ggatggagagtggaattccggcctatggaggtgcagttgacagacttcgagaactctgca
tacgtggtgtttgtggtgctgcttaccagggtgatcctgtcctacaaactggacttcctc
attcccctgtcgaaggtggacgagaacatgaaagtggcacagaagcgagacgccgtcctg
cggggcaggttttatttcagaaaagacatctgcaaaggtggcagcgctgtggtggacggc
tgcggcaaggcggcgggcgcggagccggcggccgaggagtacgcgctcatgaccatcgac
accatcatcaacggcaaggaaggcgtgttccctgggctgatccccatcctgaactcttac
ctggagaacatggaggtggatgtggacaccagatgcagtattctcaactacctgaagctg
atcaagaagagagcgtccggagaattaatgacagttgccaggtggatgagggagttcatc
gcaaagcatcctgactacaagcaagacagtgtcatcactgacaaaataaactatagcctt
cttttaaagtgtaaccaaattgcaaacgaattatgtgaatgcccagagttacttggacca
gcatttaggaaagtaaaatatagtggaagtaaaactgacccttccaactag
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