Camelus dromedarius (Arabian camel): 105100956 Help Entry 105100956         CDS       T04642                                  Symbol SYNE1 Name (RefSeq) nesprin-1 isoform X1   KO K19326   nesprin-1 Organism cdk  Camelus dromedarius (Arabian camel) Pathway cdk04820   Cytoskeleton in muscle cells Brite KEGG Orthology (KO) [BR:cdk00001]  09140 Cellular Processes   09142 Cell motility    04820 Cytoskeleton in muscle cells     105100956 (SYNE1)  09180 Brite Hierarchies   09182 Protein families: genetic information processing    03036 Chromosome and associated proteins [BR:cdk03036]     105100956 (SYNE1) Chromosome and associated proteins [BR:cdk03036]  Eukaryotic type   Centrosome formation proteins    LINC complex     105100956 (SYNE1) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  Spectrin Spectrin_SYNE1 SYNE1 CH KASH RhiE-like_linker Motif Other DBs NCBI-GeneID:  105100956 NCBI-ProteinID:  XP_031312421 LinkDB All DBs Position 8:complement(67926177..68353974) Genome browser AA seq 8832 aa AA seqDB search MATSRAASRSPRDIANVMQRLQDEQEIVQKRTFTKWINSHLAKRKPPMVVDDLFEDMKDG VKLLALLEVLSGQKLPCEQGRRMKRIHAVANIGTALQFLEGRKSMYRGSPIKLVNINSTD IADGRPSIVLGLMWTIILYFQIEELTSNLPQLQSLSSSTSSVDSMVSSETASPPSKRKVA TKIQGNAKKALLKWAQYTAKQTGTEVKDFGRSWRSGVAFHSVIHAIRPELVDLEKVKGRS NRENLEEAFRIAETELGIPRLLDPEDVDVDKPDEKSIMTYVAQFLKQYPDIHSTGADGQE NDEILPGFPSFANSIQILKREDRLVLKETKVWIEQFERDMTRAQMTESNLQDKYQSFKHF RVQYEIKRKQIEHLIQPLHRDGKLSLDQALVKQSWDRVSSRLFDWHIQLDKSLPAPLGTI GAWLYRAEVALREEITIQQVHEETANTIQRKREQHKDLLQNTDAHKRAFHEIYRTRSVNG IPVPADQLEDLAERFHFVSSTSELHLMKMEFLELKYRLLSLLVLAESKLKSWIIKYGRRD SVELLLQNYISFIENSKFFEQYEVTYQILKQTAEMYVKADGSVEEAENVMKFMNETTAQW RNLSVEVRSVRSMLEEVIANWDRYGNTVASLQAWLEDAEKMLNQSEHAKKDFFRNLPHWI QQHAAMNDAGNFLIETCDEMVSRDLKQQLLLLNGRWRELFMEVKQYARADEMDRMKKEYT DCVTALSDFATEAHRKLSEPLEVSFINVKLLVQDLEDIEQRVPVMDAQYKIITKTAHLIT KESSQEEANEMFATMSRLREQLSKVKDCYSPLLYESQQLLIPLEELEKQMTAFYDSLGKI NEILTVLEHEAQSSSLFKEKHQELLACQESCKKAMTQIEKGSHSVQKFVTLSNVLKHFDQ TKLQRQVADVHVAFQNMVKKTGDWKKHVETNSRLMKKFEESRAELEKVLRIAQEGLEEKG NPEDLLKRHTEFFSQLDQRVLNAFLKACDELTDILPEREQQGLQEAVRKLHKQWKDLQGE APYHLLHLKIEVEKNRFLESVEECRAELDRETKLVPQEGSEKIIKEHRVFFGDKGPHHVC EKRLQLIEELCLKLPVRDPVRNTPETCHVTLKELRAAIGGTYAKLVENPDKWKDYSGRIS EFSCWISTKETQLKGIKNEAIDTANHGEVKRAVEEIRDGVTKKGETLSWLKSRLKILTEV SSENEAQKQGDELAKLSSSFKALGTLLSEVEKMVSNFGDCVQYKEIVKSSLEELITGSKE IQEQAEKILDTENLFEAQQLLLHHQQKTKRISAKKRDVQQQIAQARQGEGGLPGRVREEL RKLESTLDSVEHSREKQERRIQVTLRKWERFETNKETVVRYLFQTGSSHERFLSFSSLES LSSELEQTKEFSKRTEGIAVQAENLVKEASEIPLGPRNKQLLQQQAKSIKEQVKKLEDTL EEDIKTMEMVKNKWDHFGNNLETLSVWITEKEKELNALETSSSAMDTQIHQIKVTIQEIE SKVSSITGLEEEAQSFAQFITTGESARIKAKLTQIRRYWEELREHAQCLEGTILGHLSQQ QKFEENLRNIQQSVSEFEDKLADPIKMCSSATETYKVLQEHMDLCQALESLTSTVAALSA SAQKVTDRDSSVREAEALQQRYEGLLRRAKERQTALEKLLAHWQRLEKELSTFSTWLERC EATASSPEAVISADRVKVESELQLIQALQDEVVAQASIYSNLLQLKESLFSVASKEDVKM MKLHLEQLDERWRDLPQIISKRINFLQSVVAEHEQFDELLLSFSVWIKLFLSELQTTSEI SIMDHQAALTRHKDHAAEVESKKGELQSVQGHLAKLGALGRAEDLHLLQGKAEDCFQLFE EASQVVERRQLALSQLAAFLQSHTSLSGVLHRLRQTVEATSSMNKQQSDLLEKDLNDALQ DAKTLESTAISLDGLLTKAQYHLRSGGSEQRTSCRTTVDQLCFELERIQNLLGTKQSEAD ALAVLKKAFHDQKEELLKSIEDIEERAEKERLKEPTRQALQQRLRVFNQLEDELNSHEHE LCWLKDKAKQIAQKDVAFAPEVDREVNRLEAIWDDTKKLIHENQGQCCGLIDLMREYQNL KSAVSKVLENASNVIVTRTTIKDQEDLKWALSKHETAKNEMYKKQKELDNFTSKGKQLLS ELKKIHSGDFILVKTDMESTVDKWLDISEKIEENMDRLRVSLSVWDEVLSCRDEIDGWSN SSVPQLAESISNLNDSLRAEEFLKEFESEVKKKALRLEELHSKVNDLKELTKNPETPPDL QFMEADLQQKLEHAKEITEEAKGTLKEFTAQSAQVEKFINDTATWLTKLEDSLMNCAQTE TCEGLKKVKEIQKELQSQQRSISSTQENLNSLCRKYHSVELESLGGAMLGLIKRHEAVSQ SCSKAQASLQDSLEKHFNESMQEFQEWFSGIKAAAKKSSDRTGDSKVLEAKLHDLQNILD SVSDGQSKLDAVTQEGETLYAHLSKQIVSSIQEQVTKANEEFQTFLKQCLKDKQALQDCA LELGSFEDQHRKLSLWIHEMDERLSTENLGESKQHIPEKKNEVHKIEMFLGELLAARESL DKLSQRGQLLSEEGHGAGKEGRLCSQLLTSYQNLLRVTKGKLRSCQVALQEHEALEEALQ SMWSWVKDVRDRLACAESTVGSKDALERRLLQVQDILLMKGEGEVKLNMAIGRGEQALRS SNKEGQKVIQTQLQTLKDVWANIMSSSIHAQSTLESVISQWNDYLEWKNQLEQWMESVDQ KLEHPLQLQPGLKEKFSLLDHFQSIVSEAGDHAGALQRLTAKARELYQKTEDDSFKEAAQ EELKTQFNDLLTVSKEKMRKVEEIVKDHLMYLDAVQEFTDWLHSAKEELHRWSDTSGDSS AIQKKLSKIKELMDSRETGASRLGRVESLAPAVRQNTTASGCELLDTEMQALRADWKQWE DSVSQTQTSLENLVSQMALSEQEFSGQVAQLEQALEQFSALLTGWAQQLTLLEGKNTDKE IVECWHKGREILDALQKAEPQTEDLKSQLNELCRFSRDLSTYSGKVSGLIKEYNCLCLQA SKGCQNKEQILQQRFRRAFKDFQQWLVNAKITTAKCFDIPQNISEVSTSLQKIQEFLSES EHGQHKLNMMVSKGELLNTLLTKEKANGIQAKIAAAKEDWKNFHSNLHQKESALENLKIQ MKDFEVSAEPVQEWLSKTEKTVHEGSDRLHDLPAKRREQQKLQSVLEEINCYEPQLHRLK EKAQQLWEGQAASRSFVHRVSQLSSQYLSLSNLTKEKVSRLDRIVAEHSQFSAGVRELQD WMTDAVHMLDSYCHPTSDKSVLDSRMLKLEALLSVKQEKEIQMKMIVTRGESVLQNTSPE GVPAIQQQLQSVKDMWASLLSAGIRCKSQLEGALSKWTSYQDDVRQFSSWMDSVEASLNE SERQYAELREKMAALGKAKLLNEEVLSHSSLLETIEVKGAGMTEHYVTQLEFQDLQERYG AIRERAKEAVTKSEKLVRLHQEYQRDLKAFEAWLAQEQEKLDRYSVLEGDAHTHETTLRD LQELQVHCAEGQALLNSVLHTREEVIPSGIPQTEDRALESLRQDWQAYQQRLSETRTQFN NVVNKLRLMEQKFQQVDEWLKTLEEKVNLRTGRQSNRAAKEIQLHQMKKWHEEVTTYRDE VEDVGSRAQEILDESHVSSRTGCQATQLTSRYQALLLQVLEQIQFLEEEIQSLEESELSL SSYSDWYCSTHKNFKNVAAKIDKVDKAMMGKKMKTLEGLLKDMEKGQSLLKSAREKGERA VKYLEDGEAETLRKEIHDHVEQLKELTSTVRKEHLTLEKGLHLAKEFSDKYKALTQWIGE YQEILHIPEEPKMELYEKKAQLSKYKSLQQTVLSHEPSVKSVREKGEALLELVQDVTLKD KIDQLQSDYQDLCTAGKEHVCSLEAKVRDHEDYNSELQEVEKWLLQMSGRLVAPDLMETS SLETITQQLAHHKAMMEEIAGFEDRLNNLKIKGDNLISQCADHLQAKLKQNVQAHVQGTK DSYSAVCSTAQRVYQSLEHELQKHVSRQDTLQQCQAWLSAVQPDLKPSTYPPLSRAEAVK QVKHFRALQEQARTYLDLLCSMCDLSNSSVKTTAKDIQQTEQMIEQRLAQAQNLTQGWEE IKHMKAELWIYLQDADQQLQNMKRRHSELELNIAQNMVSQVKDFLKKLQSKQASVTTITE KVDKLTKKQESPEHKEISHLNDQWLDLCLQSTNLCLQREEDLQRTRDYHDCLDVVEVFLE KFTTEWDNLARSDAESTAVHLEALRKLALALQERKQAIDDLKERKQKMVEHLNLDDKELV KEQTSHLEQRWFQLEDLVKRKIQASITNLEELSVVRSRFQELMQWAEEQQPTIAEALKQS PPPDMAQSLLMDHLAICSELEAKQMLLKSLIKDADRVMTDLGLNERQMIQKALSDAQRHV NSLSDLVGQRRKYLNKALSEKTQFLIAVFQATSQIQQHERKIMFREHICLLPDDVSKQVK TCRSAQASLKTYQNEVTGLWAQGRELMKGATEQEKNEVLGKLQELQSVYDTVLQKCSHRL QELEKNLVSRKHFKEDFDKACHWLKQADIITFPEINLMNESPELHTQLAKYQHILEQSPE YENLLLTLQRTGQAMLPSLNEVDHSYLNEKLSALPLQFNVIVDLAKDKFYKVQEAILAQK EYASLIELTTQTLSELEDQFSKMSQVPTDLVVGEALSLQDGCRALAGEVAGLAEAVDELN QKKESFRSTGQPWQPDKMLHLVTLYHRLKRQTEQRVSLLEDTTSAYQEHEKMCQQLEKQL EGVKTEQSKVNEETLPAEEKLKLYHSLAGSLRESGILLKRVAVHLEDLVPHLDPLAYEKA KHQMQSWQEELKQLTSAIGATVTECESRMVQSRDFQTELSRSLDWLRGVKAELSGPLCLD LNLRDIQEEIRKVQIHQEEVQSSLRIMNALSDREQEKFTKAKELISADLQHTLAELAELD GDVQEALRTRQATLTQIYSQCQRYYQVFQAANDWLEDAHEMLQLTGNGLDVESAEESLKS HMEFFSTEDQFHSSLEELQGLVANLDPLIKPTGKEDLAQKMTSLEEKSQRILQDSHAQSD LLQRCAAQWQDYQKAREEVIELMNDAEKKLSEFSLLKTSSSLEAEEKLSEHKALVSVVNS FHEKIVALEGRASDLERSGNDSSKATIGRSRTAVRQRWTRLRAVAQDQEKILEDAVDEWK GFNEKVKKATEMIDQLQEKLPGSSAEKASKAELLTLLEHHDALALELEQQQSALGMLRRQ ALSMLRDGATPTPGAEPAAVRGVAVLQERCLNMQEKVKKNGQVAKQELKERQVVETHINS VKAWVQETKEYLGNPTLEVDAQLEELKILLTEATNHRQNIEEMAEEQKNKYLDLYTILPS ELSLQLAEVALDLETIHDQIQDKVKEVEQSKAMSQEFSRQIQKIAKDLTTILTKLRAKTD NLVQAKTDQKALGEELECCNLKLMELNEAVQKFSEQNGQLGKPLAKKIGKLTELHQQTIR QAENRLSKLSQAASHLEEYNEILELILKWIEKAKVLVHGKIAWNSASQLREQYILHQTML EESEEIDNDLEAMTEKLQSLDSVYHTGKMSQQVAELGRETEELRQMIKIRLQNLHDAAKD MKKFETELRNLQVALEQAQTTLTSPEVGRLSLKEQLSHRQHLLSEMESLKPKVHAVQTCQ SALRIPEDVVTSLPLCHAALHLQEEASRLQHTAIQQCNIMQEAVVQYEQYEQEMQHLQEL IEGAHREIEDKPVATSNIQELQAQISRHEELAQKIKGYQEQIASLNSKCKMLTMKAKHAT MLLTVTEVEGLAEGTEDLDGELLPATSAHPSVVMMTAGRCHTLLSPVTEESGEEGTNSEI SSPPACRSPSPVANTDASVNQDIAYYQALSAERLQTDAAKIPPGTLPSQELYEPGLEPSA TAKLDDLQRSWETLKNVISEKQRTLYEALERQQKYQDSLQSISTKMEAIEMKLSESLEHG RSPESQMAEHQSLPQALMDEILMLQEEISELQSALAEELVSESPESDPAEQLALQSTLTV LAERMSTIKMKASGKRQLLEEKLNDQLEEQRQEQALQRYLCEAEELDHWLLSTKATLDIA LGTPEEPMDMEAQLVDCQNMLVEIEQKVVALSELSVHNENLLLEGKAHTKDEAEQLAVKL RTLKGNLLELQRALHDKQLNIQQGTAQEKEESDADLAATQSPGVQEWLAQARTAWTHQRQ SSLQQQKELEQELAEQKSLLRSVASRGEEILTQHSAAETFGGAGEKPDVLSQELGMEGEK SPAEDQMRMKWESLHQEFSTKQKLLQNVLEQEQEQVLYSRPNRLLSGVPLYKGDGQAQDK SAVTSLLDGLNQAFEEVSSQGGGTKRQNIHLEQKLYDGVSATSTWLDDVEERLFVATALL PEETETCLFNQETLAKDIKEMSEEMDKNKILFSQAFPENGDNRGVIEDTLGCLLGRLSLL DSVVNQRCHQMKERLQQILNFQNDLKVLFTSLADHKYIILQKLATVLEQPVAEQIEAIQQ AEDGLKELDAGIIELKRRADKLQVEQPSMQELSRLQDMYDELMVTIGSRRSGLNQNLALK SQYERALQDLADLLDTGREKMAGDQKIIVSSKEEIQQLLDKHKEYFQGLESHMILTETLF RKIISFAVQRETQFHTELMAQAAAVLKRAHKRGVELEYILETWSHLDEDHRELSRQLEVV EGSIPSVGLVEESEDRLIDRITLYQHLKSSLNEYQPKLYQVLDDGKRLLISISCSDLESQ LNQLGEHWLNDTNKVSKELHRLETILKHWTRYQSESAGLIHWLQSAKDRLEFWTQQSVTV PQELEMVRDHLNAFLEFSKEVDAKSTLKSSVLSTGNQLLRLKKVDTAALRSELSHIDGQW TDLLTNIPAVQEKLHQLQMDKLPSRHAISEVMAWISLMENVIQKDEENIKNSIGYKAIHE YLQKYKGFKIDINCKQLTVDFVNQSVLQISSQDVESKRSDKTDFAEQLGAMNKSWQILQG LVTEKIQLLEGLLESWSEYENNVQCLKTWFETQEKRLKQQHRIGDQASVQNAMKDCQDLE DLIKAKEKEVEKIEQNGLALIQNKNEEVSGVVMSTLRELNQTWADLDHMVEQLKILLKSV LDQWSHHKAAFDEINSRLTEARYSLSRFRLLTGSLEAVQVQVDNLQNLQDDLEKQEKSLQ KFGSITNQLLKECHPPVTETLTNTLKEVNLRWNNLLEEIAEQLHSSKALLQLWQRYKDYS KQCASTVQQQEGRTNELLKAATDKDIADDEVATWIQDCNDLLKGLETVKDSLFVLHELGE QLKQQVDASAASAIQSDQVSLSQHLGALEQALCKQQTMLQAGVLDYETFTKSLEALEAWI VEAEEILQAQDPSHSSDLSTIQERMEELKGQMLKFSSMVPDLDRLNELGYRLPLNDKEIK RMQNLNRHWSLISSQTTERFSKLQSFLLQHQTFLEKCETWMEFLVQTEQKLAVEISGNYQ HLLEQQRAHELFQAEMFSRQQILHSIIIDGQRLLEQGQVDDRDEFNLKLTLLSNQWQGVI RRAQQRRGIIDSQIRQWQRYREMAEKLRKWLVEVSYVPATGLGSVPIPLQQARTLFDDAQ FKEKVLLRQQGSYILTVEAGKQLLLSADGGAEAALQAELTEMQEKWRSASVHLEEQKKKL AFLLQDWEKCENGIADSLEKLRTFKKRLSQPLPDHHEELHAEQMHCKELETAIGSWTDDL AQLTLLKDTLCAYISADDISILNERMELLQRQWEELCHQLSLRRQQVSERLNEWAVFSEK NKELCEWLTQMESKVSQNGDILIEEMIEKLRKDYQEEIAIAQENKIQLQQMGERLARASH ESKASEIEYKLGKINDRWQHLLDLMAARVKKLKETLVAVQQLDKNMSSLRTWLAHIESEL AKPIVYDSCDSEEIQRKLNEQQELQRDIEKHSTGVASVLNLCEVLLHDCDACATDAECDS IQQATRNLDRRWRNICAMSMERRLKIEETWRLWQKFLDDYSRFEEWLKISERTAAFPSSS GVLYTVAKEELKKFEAFQRQVHECLTQLELINKQYRRLARENRTDSACSLKQMVHEGNQR WDNLQKRVTSILRRLKHFIGQREEFETARDSILVWLTEMDLQLTNIEHFSECDVQAKIKQ LKAFQQEISLNHSKIEQIIAQGEQLIEKSEPLDAAVIEDELDELRRYCQEVFGRVERYHK KLIRLPLPDDEQDLSDRELELDESAALSDLHWRDTSADSVLSPQPSSNPSLSLAQPLRSE RSGRDTPASVDSIPLEWDHDYDLSRDLESAVSRTLPSEDEEGQEEKDFYLRGAVGLSDVV IPESPEAYVKLTESAIRNSSGDPSALESQIRQLGKALDDSRFHMQPTETIIRSKTPTGPE LDSSYRGYMKLLGECSGSIDSVKRLEHELKEEEDHFPGFVNLNSTETQTAGVIDRWELIQ AQALSKELRMKQNPQRQQQFDSDLSSTLAWLRETEDDLEQLRRLQLSTDIQSIALQIQKL KELQKAVDHRKAIILSINLCSSEFTQAGQEESQDLQDRLSQMNGRWDRVCSLLEEWRGLL QDALMQCQDFHEMSHGLLLMLENIDRRKNEIVPIDSNLDVEMLQDHHKQLTQIRRELLDT QFKVASLQDMSCQLLVNAEGTDCLEAKEKVHVIGNRLKLLLKEVSRHIKELEKLLDMSSS QQDLSSWSSADELDTSGSVSPTSGRSTPNRQRTPRGKCSLSQPGPSVNSPHSRSIKGGSD SSLSEPQPARSGRAFLFRVLRAAVPLQLLLLLLVGLACLVPVSEEDYSCALSNNFARSFH PMLRYTNGPPPL NT seq 26499 nt NT seq  +upstreamnt  +downstreamnt atggcaacctccagggcagcctctcggtctcctcgggacatcgccaacgtgatgcaaagg ctacaagatgagcaagagatagtacagaaacgtacttttacaaaatggatcaactctcat ctggccaagcggaaacccccaatggtggtagatgatctttttgaagacatgaaagatggt gtgaagctacttgctctcctggaggtcctgtctgggcagaaactgccatgtgaacaggga cgccgtatgaagcggatccatgctgtggctaacatcggcacggcacttcagttccttgaa ggaaggaagtccatgtacagaggatcaccgataaaactagtcaacattaactccacggat atagcggatggccgaccctcgatagttcttggattgatgtggacgatcatcctgtatttc cagattgaggagctgaccagcaacctgccgcagctgcagtctctgtccagcagcacatcc tctgtggacagcatggtcagctcggagaccgccagccccccgagcaaacggaaggtggcc accaagatccaaggaaatgctaagaaggctttgttaaagtgggctcagtacacagccaag cagactggaacagaagtgaaagacttcgggcggagctggagaagtggggttgcctttcat tcggtcatccacgctattcggccggaactggtggacttggagaaagtgaaagggagatct aaccgagaaaacctggaggaggctttcaggattgctgagacggaactgggaatcccgcga ctcctagatcccgaagatgtggacgtggataaaccagatgagaagtctattatgacttac gtagcccagtttctgaaacagtatcctgacatccacagcacaggcgctgatgggcaagag aatgatgaaatacttccaggtttcccatcttttgcaaattctatccaaattcttaagaga gaagataggctggttttgaaggaaacgaaagtttggatagaacaatttgaaagagatatg acgagggcacagatgacagaatcaaatttgcaggataaatatcagtcatttaagcacttc agagttcaatatgaaataaaaaggaaacagattgaacatttaatacagccgttacataga gatggcaaactgtcactcgaccaagcattggtaaagcagtcctgggatagagtgtcctcc aggctctttgattggcatattcagcttgataagtctcttcctgcccctctgggcaccatc ggggcctggttatacagagcagaggtggccctgcgagaggaaataaccattcagcaggtt cacgaggaaacggccaacacaatacagcggaagcgtgagcagcacaaggatctgcttcaa aacacagatgcccacaaaagagcattccatgaaatctaccggaccaggtctgttaacggg atcccagtgccagccgatcaattagaggacctggccgagaggtttcattttgtgtcctcc acgtcagagctacacttaatgaaaatggaatttctagaattaaagtaccgtctgctctca ctgctggttcttgcagagtcaaagctgaagtcttggatcatcaagtatgggaggagagac tcagtagagctgcttctgcaaaactacatctctttcatagaaaacagcaagttctttgaa caatatgaagtgacataccagatcttgaaacagacagccgagatgtatgtcaaagccgat ggctcagtggaggaagctgagaatgtgatgaaattcatgaatgaaaccactgctcagtgg aggaacctctcagtagaagtcaggagcgtgcggagcatgctggaagaagtcattgctaac tgggaccgatacggcaatactgtggctagtcttcaggcttggctggaggatgctgagaaa atgctaaatcagtcagaacatgccaagaaggatttttttcgaaatttgcctcattggata cagcagcacgccgccatgaacgatgctggcaattttctgattgagacatgtgacgagatg gtttcccgcgatcttaaacagcagttactgctgctaaacgggcggtggagggagttgttt atggaagtcaagcaatatgcccgagccgacgagatggacagaatgaagaaggagtacaca gattgtgttactgccctgtctgactttgcaactgaagcccacaggaaactctctgagcca ctggaagtctcttttattaacgtgaagttattagttcaagacttggaggatattgagcag agggtgcctgtgatggacgctcagtataagataattacaaagacagcacatctcattacc aaagagagctcccaagaagaagcgaacgaaatgtttgcaaccatgtccaggctcagagag cagctaagcaaggtcaaagactgttactctccactcctttatgagtctcaacagctgttg ataccgttggaggaattagaaaaacagatgacagccttttatgactcacttgggaaaatc aatgaaattttaacagttcttgagcacgaggcacaatccagctctctttttaaagagaaa catcaggaactattagcttgtcaagaaagctgtaagaaagccatgacccaaattgagaaa ggcagtcatagtgttcaaaagtttgtgaccttgagcaacgtgttaaagcattttgatcag acgaagctccagagacaggttgcggatgtgcacgttgcttttcagaatatggtaaagaaa actggcgattggaagaaacacgtggaaacgaacagccgcttgatgaagaaatttgaggag tctcgagcagagctggagaaggtgttgaggatcgcacaggagggcctggaggaaaagggg aatccagaagacctcctgaaaagacacacagagtttttcagtcagctggatcagagggtg ctcaacgcgttcctgaaggcttgtgacgaactcacggacatcctccccgagcgggagcag cagggcctgcaggaagctgtgaggaaactccacaaacagtggaaggatcttcaaggagaa gctccgtatcatttgcttcatctgaagattgaggtggagaagaacaggtttttagaatct gtggaagaatgcagagctgagctggaccgagagaccaagctggtgccccaggaaggcagt gagaagatcatcaaagagcacagggtcttcttcggtgacaaaggtcctcatcatgtctgt gagaaaaggctacagctcattgaagaactgtgtctgaaactcccggtccgggacccagtc cggaacacgcctgagacctgtcacgtgaccctcaaggagctcagagcggccattggcggc acctacgccaagctggtggagaacccggacaagtggaaggactacagtggcagaatttct gagttttcctgttggatctctacaaaggagacccaactgaaggggattaaaaacgaggcc atcgatactgccaaccatggagaggttaaacgtgctgtagaggagatcagagatggtgtt accaaaaagggtgagactctcagctggctgaaatccaggcttaaaattttgactgaagtt tcttctgagaatgaagcccaaaagcaaggagatgagctggcaaaattatctagttccttc aaggctctcgggactttgctgtcagaggttgaaaagatggtaagcaactttggagattgt gtccagtacaaagaaatagttaaaagttcccttgaagagttaattactggctctaaagaa atccaggaacaagccgagaagatcttggacactgaaaatctgtttgaagcacagcagcta ctccttcatcaccagcaaaagacaaagagaatctccgcaaagaagagggacgtgcagcag cagattgcgcaggctcggcagggagaaggtgggctgcccggccgggtccgagaggagctg cggaagctggagagcaccctggacagcgtggagcacagccgggagaagcaggaacgccgc atccaggtcacattaaggaaatgggagagatttgaaacaaacaaagagacagtggtcaga tacctttttcaaacaggttccagccatgagcgcttcttgagttttagcagtttggaaagc ttatcttcagaactggaacaaacaaaggagttttctaaacgaacagaaggtattgcagtc caggctgagaatcttgtgaaggaagcttccgagatcccactggggcccaggaataagcag ctgcttcagcagcaggccaagtcaatcaaagagcaagtcaaaaaattagaagacacactt gaagaagatattaaaaccatggaaatggtgaaaaacaagtgggatcattttggcaataat cttgagaccctgtctgtctggataactgagaaagaaaaagaactcaatgccttggaaact tcgtcatctgccatggacacacaaatccaccaaatcaaggtcacaattcaggaaatagaa 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caaaatattagtgaagtttcaacaagtcttcagaaaatacaggaatttttgtcagaaagc gaacatggacagcacaagctgaacatgatggtttctaagggagagcttttgaatactctg ttgaccaaagagaaggcaaacggaatccaggccaaaattgcagctgccaaagaggactgg aaaaatttccattcaaatctccaccagaaggaatctgccctagagaatctaaagatccaa atgaaggactttgaagtaagcgctgagcccgtccaggagtggctgagtaaaaccgagaag acggtgcacgaaggcagcgaccgcctgcacgacctgccggcaaagaggcgagaacagcag aagctgcagtctgtccttgaggaaataaactgctacgagcctcagctccacaggctgaaa gagaaagctcaacagctgtgggaaggccaggctgccagcaggagctttgtgcacagagtg tcccagctgtcttctcagtatctatccctaagcaatttaacgaaggagaaagtgtcaagg ttggatagaattgttgctgagcacagccagttttccgctggggttagagagttgcaggac tggatgacagacgccgtgcacatgctggattcctactgccacccgacgtcggacaagagc gtgctggacagcaggatgctcaagctggaggctctattatccgtgaaacaggaaaaagag atccagatgaaaatgatagtgaccagaggggagtctgtccttcagaatacctctccggaa ggtgtccctgccattcagcagcagctgcagagtgtgaaggacatgtgggcgtcccttttg tccgccgggattcgttgtaaaagtcaactcgaaggagctctttctaagtggacaagttac caggatgacgtccggcagttctccagttggatggacagcgtggaggccagtctgaatgaa 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tccatctccacgaagatggaggccatcgagatgaaactcagtgagagtctagagcatgga aggagtccagagagccagatggccgaacatcagtctctcccacaggccctgatggatgag attctcatgctgcaggaagagatcagcgagctccagtcggccctggcggaggagctggtg tccgagtccccggagtccgaccctgcggagcagctggccttgcagtccacgctcaccgtc ttagcagagcgcatgtccaccatcaagatgaaagcatctgggaaacgccagcttttggag gagaagttaaatgatcaactggaggaacagagacaggaacaggcccttcagaggtatctc tgtgaagccgaggagctggaccactggctcttgagcacgaaggccactctggacattgcc ctggggacacctgaggagcccatggatatggaggcccagctggtggactgccagaacatg ctggtggaaatagagcagaaggtggtggccttatcagagctctcagtgcacaatgaaaac ctgctgctggagggcaaggctcacacgaaggatgaggctgagcagctggcagtcaagctg aggaccctcaaggggaacctcctggagctgcagagagcgctgcatgacaagcagctcaac atccagcagggaacagcacaggagaaggaggagagcgatgctgacctggctgccactcag agccctggggttcaggaatggctggctcaagcccgtaccgcgtggacccaccagcgacag agcagtctccagcaacaaaaagagttggaacaggaattagcagagcagaagagcctcctc cggtcagtagccagtcgtggagaagaaatcctaacccaacactcagctgcagaaaccttt ggtggtgctggcgaaaaacctgatgtgttatcccaggagttggggatggaaggggagaaa tcacctgctgaagaccagatgagaatgaaatgggaaagcctacatcaagaatttagtacc aagcagaaactacttcagaatgttctggaacaggaacaagagcaagtgctttacagcagg ccaaatcggctcctgtctggcgtaccactgtacaagggggacgggcaggcccaagataaa tccgcggtgacgtctttgctggatggactgaaccaggccttcgaggaggtttcatcccag ggcggggggacaaagaggcagaacattcacttggaacagaagttgtatgatggggtctca gctacctccacttggttggacgacgttgaggaacgtttatttgttgccacggcactttta ccggaagagacggaaacttgcctcttcaaccaagagactcttgccaaagatattaaggaa atgtctgaagaaatggataagaacaagatcttgttttcccaagcatttccagagaacggc gataaccgaggtgttattgaagacactttgggttgtcttttgggcaggttatctttgcta gactcagtagtaaatcagcgatgtcatcagatgaaggaaagacttcagcagattctaaat ttccagaatgatctgaaggtgctgtttacatcactggctgaccacaaatacatcattctg cagaaactggcaactgtgttggaacagcctgtggcagagcaaatagaggcaatacagcag gctgaagatgggctgaaggaattggatgcaggaatcattgagttaaaaaggcgtgctgac aagctgcaggtggagcagccttccatgcaagaactctccagacttcaggacatgtatgat gagctgatggtgaccattggctcccggcggagtggtctgaaccagaatcttgctctcaag agtcagtatgaaagggccctgcaagatctggctgacctgctggacactggacgagagaag 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gttattcaaaaggatgaagagaatattaaaaattccatcggttacaaggccattcatgaa taccttcagaaatacaagggttttaagatcgacattaactgtaaacagctgacagttgat tttgtgaaccagtctgtgctacaaatcagcagtcaggatgtggaaagtaaacgcagtgat aagactgattttgctgagcagcttggagcaatgaataaaagttggcaaatcctgcagggt ctagtaactgagaagattcagctgttggaaggcttactggaatcttggtcagaatatgaa aataatgtacagtgtctgaaaacttggtttgaaacccaagaaaagagactaaaacaacaa catcgaattggcgatcaggcttcagttcagaacgcgatgaaagactgtcaggacctggaa gatttgattaaagcaaaagaaaaagaagtagagaaaattgagcagaatggacttgctttg attcagaacaagaatgaagaagtctctggcgttgtcatgagcacgctgagggagctcaac caaacctgggcagacttagaccacatggttgagcaattaaagatcctgctgaagtccgtg cttgaccagtggagccaccacaaagcagcctttgatgagataaacagccgcctcacagag gccaggtactctctttcccgattccgcctgctgaccggctctttagaagctgtgcaagtt caggtagacaatcttcagaatcttcaagatgacctggaaaaacaggaaaagagcttacag aaatttggctctatcaccaaccagctattaaaagagtgtcacccacctgtgacagaaact cttaccaatacgctcaaagaagtcaacctgagatggaataacttgctggaagagattgct gagcagctgcactccagcaaggccctacttcagctctggcaacgatacaaggactactcc aaacagtgtgcttccacagttcaacagcaggagggtcgaaccaatgagctcctgaaggca gccacggacaaggacatcgctgacgacgaggttgccacatggattcaagactgcaacgac ctcctcaaaggactggagacagttaaggattccctttttgttctccatgaactgggagag caactcaagcagcaagtggacgcttcggctgcatcagccattcagtctgatcaagtgtct ttgagtcaacacttgggtgccctggaacaggctctttgcaagcagcagacgatgttacag gctggagttcttgactatgaaacctttaccaagagtttagaagctttggaggcctggata gtagaagctgaagaaatccttcaggcgcaagaccctagccactcatctgacctttccacc atccaggaaaggatggaagaacttaagggacagatgttaaaattcagcagcatggtccca gacttggatcgtctgaatgagctcgggtatcggttacccctgaatgataaagaaatcaaa aggatgcagaatctgaaccggcactggtctctgatctcctctcagactacagaaagattc agtaagttacagtcatttttgctacaacatcagactttcttggaaaaatgtgaaacatgg atggaattcctggttcaaacagaacaaaagttagcagtagagatttcgggcaattatcag catcttttggagcagcagagagcacatgagttgtttcaagcagagatgttcagtcgtcag cagattttgcactcgatcattattgatgggcagcgtcttctagaacaaggtcaagttgat gacagggatgaattcaacctgaagctgacacttctcagtaatcagtggcagggggtgatc cgcagggcccagcagaggcggggcatcatcgacagccagattcgccagtggcaacgctat 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cagctggataagaacatgagcagcctgaggacgtggctggcccacatcgagtcagagctg gccaagccgatcgtctatgattcctgtgactcggaagaaatacagagaaagcttaatgag caacaggagcttcagagagacatagaaaaacacagcacgggcgtggcctctgtcctcaac ctgtgtgaggttctgctgcatgactgcgatgcctgtgccacggacgccgagtgtgattcc atccagcaggctacacggaacctggaccggcgatggagaaacatctgcgctatgtccatg gaaagaaggctcaaaattgaagagacgtggcgattgtggcagaagtttctggatgactat tctcgttttgaagagtggctgaagatttcagaaaggactgctgccttccccagctcttct ggggtgctctatacagttgccaaggaagaactaaagaaatttgaggctttccagcgacag gtccacgagtgcctgacccagctggagctgatcaacaagcagtaccgccggctggccagg gagaaccgcaccgactccgcctgcagcctgaagcagatggttcacgagggcaaccagaga tgggacaacctgcaaaagcgtgtcacctccatcttgcgccgactcaagcatttcattggc cagcgtgaggagtttgagactgcacgggacagcattctggtgtggctgacagagatggat ttgcagctcactaacattgagcatttttccgagtgtgatgttcaagctaaaataaagcag ctcaaggccttccagcaggaaatttcactgaaccacagtaagattgagcagatcatcgcc caaggagaacagctgatagagaagagcgagccactggacgccgcggtcatcgaggacgag ctggatgagctccggcggtactgtcaggaggtctttgggcgcgtggaaagataccataag aagctgattcgcctgcctctcccagacgatgagcaggacctctctgaccgggagctggag ctggatgagtctgctgctctctcagacctccactggcgagacacctcggcagacagtgtg ctctccccccagccttcctccaacccctccctctcactggcccagcccctccggagcgag cggtcgggacgagacacccctgccagtgtggactccatccccctggagtgggaccatgac tatgacctcagtcgtgacctcgagtctgccgtgtccagaactttgccctccgaggacgaa gagggtcaggaggaaaaagatttctacctcaggggagctgttggcctatcagatgtagtg attcccgaaagtcctgaggcgtatgtaaaactcacagaaagtgcaatcagaaattcctct ggggatcccagtgccttagagtcgcagatccgacagctgggcaaagccctggatgacagc cgctttcacatgcagccaacagagactatcatccgcagcaaaactcccacaggaccagag ctagactccagctacagaggctatatgaaactgctcggtgaatgcagtggcagtatagac tcggtgaagagactggaacacgaactgaaggaggaggaggaccatttccccggctttgtt aacctgaacagcacagaaacgcaaacagccggtgtgattgaccgctgggagctcatccag gcacaggccctgagcaaggagctgaggatgaaacagaacccccagaggcagcagcagttc gactccgacctgagcagcacgctggcctggctccgggagaccgaggacgacctggagcag ctccggcgcctgcagctcagcaccgatatccagtccatcgcgctccagatccaaaagctc aaggagctccagaaagctgtggaccaccgcaaagccatcatcctctccatcaatctgtgc agctccgagttcactcaggctggccaagaggagagccaggatctgcaggatcgcttgtcc cagatgaatgggcgctgggaccgcgtgtgctccttgctggaggagtggcggggccttctc caggatgcactgatgcagtgccaggatttccatgaaatgagccatggtttgcttcttatg ctggagaacatcgacagaaggaaaaatgaaattgtccccattgattctaaccttgatgta gagatgcttcaggaccatcacaaacagctcacgcaaataagacgtgagctgttagatacc caattcaaagtggcctcactgcaagacatgtcttgccaactattggtgaatgctgaaggc acagactgtttagaagccaaagaaaaagtccatgtgattggaaatcggctcaaactcctc ttgaaggaggtcagtcgtcatatcaaggagctggagaagttattagacatgtcaagcagt cagcaggatctgtcctcctggtcttctgctgatgaactggacacctcaggatctgtgagt cctacatcgggaagaagtaccccaaacagacagagaacgccacgaggcaaatgtagtctc tcacagcctggaccctctgtcaacagtccacatagcaggtccataaaaggtggctccgat tcctccctttctgagccccagccagctcggtccggccgagccttcctgttccgggtcctc cgggcggctgtcccacttcagcttctgctgctgcttctcgtcgggctcgcctgccttgtg ccagtgtccgaggaagactacagctgtgccctctccaacaattttgcccgatcattccac cccatgctcagatacaccaacggcccgcctccactctga

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