Camelus dromedarius (Arabian camel): 105101970 Help Entry 105101970         CDS       T04642                                  Symbol JAK2 Name (RefSeq) tyrosine-protein kinase JAK2   KO K04447   Janus kinase 2 [EC:2.7.10.2] Organism cdk  Camelus dromedarius (Arabian camel) Pathway cdk01521   EGFR tyrosine kinase inhibitor resistance cdk04062   Chemokine signaling pathway cdk04081   Hormone signaling cdk04148   Efferocytosis cdk04151   PI3K-Akt signaling pathway cdk04217   Necroptosis cdk04550   Signaling pathways regulating pluripotency of stem cells cdk04630   JAK-STAT signaling pathway cdk04658   Th1 and Th2 cell differentiation cdk04659   Th17 cell differentiation cdk04725   Cholinergic synapse cdk04917   Prolactin signaling pathway cdk04920   Adipocytokine signaling pathway cdk04933   AGE-RAGE signaling pathway in diabetic complications cdk04935   Growth hormone synthesis, secretion and action cdk05140   Leishmaniasis cdk05145   Toxoplasmosis cdk05152   Tuberculosis cdk05161   Hepatitis B cdk05164   Influenza A cdk05167   Kaposi sarcoma-associated herpesvirus infection cdk05168   Herpes simplex virus 1 infection cdk05200   Pathways in cancer cdk05207   Chemical carcinogenesis - receptor activation cdk05235   PD-L1 expression and PD-1 checkpoint pathway in cancer cdk05417   Lipid and atherosclerosis Brite KEGG Orthology (KO) [BR:cdk00001]  09130 Environmental Information Processing   09132 Signal transduction    04630 JAK-STAT signaling pathway     105101970 (JAK2)    04151 PI3K-Akt signaling pathway     105101970 (JAK2)   09133 Signaling molecules and interaction    04081 Hormone signaling     105101970 (JAK2)  09140 Cellular Processes   09141 Transport and catabolism    04148 Efferocytosis     105101970 (JAK2)   09143 Cell growth and death    04217 Necroptosis     105101970 (JAK2)   09144 Cellular community - eukaryotes    04550 Signaling pathways regulating pluripotency of stem cells     105101970 (JAK2)  09150 Organismal Systems   09151 Immune system    04658 Th1 and Th2 cell differentiation     105101970 (JAK2)    04659 Th17 cell differentiation     105101970 (JAK2)    04062 Chemokine signaling pathway     105101970 (JAK2)   09152 Endocrine system    04920 Adipocytokine signaling pathway     105101970 (JAK2)    04917 Prolactin signaling pathway     105101970 (JAK2)    04935 Growth hormone synthesis, secretion and action     105101970 (JAK2)   09156 Nervous system    04725 Cholinergic synapse     105101970 (JAK2)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     105101970 (JAK2)    05207 Chemical carcinogenesis - receptor activation     105101970 (JAK2)    05235 PD-L1 expression and PD-1 checkpoint pathway in cancer     105101970 (JAK2)   09172 Infectious disease: viral    05161 Hepatitis B     105101970 (JAK2)    05164 Influenza A     105101970 (JAK2)    05168 Herpes simplex virus 1 infection     105101970 (JAK2)    05167 Kaposi sarcoma-associated herpesvirus infection     105101970 (JAK2)   09171 Infectious disease: bacterial    05152 Tuberculosis     105101970 (JAK2)   09174 Infectious disease: parasitic    05145 Toxoplasmosis     105101970 (JAK2)    05140 Leishmaniasis     105101970 (JAK2)   09166 Cardiovascular disease    05417 Lipid and atherosclerosis     105101970 (JAK2)   09167 Endocrine and metabolic disease    04933 AGE-RAGE signaling pathway in diabetic complications     105101970 (JAK2)   09176 Drug resistance: antineoplastic    01521 EGFR tyrosine kinase inhibitor resistance     105101970 (JAK2)  09180 Brite Hierarchies   09181 Protein families: metabolism    01001 Protein kinases [BR:cdk01001]     105101970 (JAK2) Enzymes [BR:cdk01000]  2. Transferases   2.7  Transferring phosphorus-containing groups    2.7.10  Protein-tyrosine kinases     2.7.10.2  non-specific protein-tyrosine kinase      105101970 (JAK2) Protein kinases [BR:cdk01001]  Non-receptor tyrosine kinases   JAK family [OT]    105101970 (JAK2) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  PK_Tyr_Ser-Thr Pkinase FERM_F2 FERM_F1 SH2_1 Jak1_Phl SH2 ABC1 FERM_C_FAK1 RIO1 Kinase-like FERM_M Motif Other DBs NCBI-GeneID:  105101970 NCBI-ProteinID:  XP_010993540 LinkDB All DBs Position 4:complement(19068763..19155684) Genome browser AA seq 1130 aa AA seqDB search MACLTMTEMEGTSASPIHQNGDIPGNANSVKEIDPVLQVYLYHSLGKAEGEYLKFPPGEY VAEEICVAASKACGITPVYHSMFALMSETERIWYPPNHVFHIDESTKHSVLYRIRFYFPY WYCNGSNRTYRHGISRGAEAPLLDDFVMSYLFAQWRHDFLHGWIKVPVTHETQEECLGMA VLDMMRIAKEKDQTPLDIYSSISYKTFLPKCVRAKIQDYHILTRKRIRYRFRRFIEQFSH CKATARNLKLKYLINLETLQSAFYTEQFEVKEPGRGPSGEEIFATIVITGNGGIQWSRGK HKESETLTEQGLQLYCDFPDIIDVSIKQANQEGSNESRIVTIHKQDGKSLEIELSSLSEA LSFVSLIDGYYRLTADAHHYLCKEVAPPMVLENIQSNCHGPISMDFAISKLKKAGNQTGL YVLRCSPKDFNKYFLTFAVERENVIEYKHCLITKNENGEYNLSGTKKNFNNLKDLLNCYQ METVRSDSIIFQFTKCCPPKPKDKSNLLVFRTNGISDIPTSPTLQRHNNVNQMVFHKIRN EDLMFNESLGQGTFTKIFKGVRREVGDYGQLHETEVLLKVLDKAHRNYSESFFEAASMMS QLSHKHLVLNYGVCVCGEENILVQEFVKFGSLDTYLKKNKNSINILWKLEVAKQLAWAMH FLEEKTLIHGNVCAKNILLIREEDRKTGNPPFIKLSDPGISITVLPKDILQERIPWVPPE CIENPKNLNLATDKWSFGTTLWEICSGGDKPLSALDSQRKLQFYEDRHQLPAPKWTELAN LINNCMDYEPDFRPSFRAIIRDLNSLFTPDYELLTENDMLPNMRIGALGFSGAFEDRDPT QFEERHLKFLQQLGKGNFGSVEMCRYDPLQDNTGEVVAVKKLQHSTEEHLRDFEREIEIL KSLQHDNIVKYKGVCYSAGRRNLRLIMEYLPYGSLREYLQKHKERIDHKKLLQYTSQICK GMEYLGTKRYIHRDLATRNILVENENRVKIGDFGLTKVLPQDKEYYKVKEPGESPIFWYA PESLTESKFSVASDVWSFGVVLYELFTYIEKSKSPPAEFMRMIGNDKQGQMIVFHLIELL KNNGRLPRPDGCPDEIYVIMTECWNNNVNQRPSFRDLAFRVDQIRDNMAG NT seq 3393 nt NT seq  +upstreamnt  +downstreamnt atggcttgccttacaatgacagaaatggaaggaacatctgcatcccctatacatcagaat ggtgatattcctggaaatgctaattctgtgaaggaaatagatccagtcctacaggtgtat ctttatcattcccttgggaaagctgagggagagtatctaaagtttccacctggggagtac gttgcagaagaaatttgtgttgctgcttctaaagcttgtggaatcacacctgtgtatcat agtatgtttgctttaatgagtgaaacagaaaggatctggtacccacccaaccatgtcttc catatagatgaatcaaccaagcacagtgtactctacagaatcagattttactttccctac tggtattgtaatggcagcaacagaacctatcggcatggaatatctcgaggtgctgaagct cctcttcttgacgactttgtcatgtcttacctttttgctcagtggcggcatgattttttg catggatggataaaagtacctgtgactcatgaaacacaggaagaatgtcttgggatggcg gtattagatatgatgagaatagctaaagaaaaggatcaaactccactggacatctatagc tctatcagctacaagacattcttaccaaaatgtgtccgagcaaagatccaggactatcat attttgacaaggaagcgaataaggtacagatttcgccgatttattgagcagttcagccat tgcaaagccactgccagaaacttgaaacttaagtatcttataaatctggaaactcttcag tctgccttctacacagagcaatttgaagtaaaagaacctggaagaggtccttcaggtgag gagatttttgcaaccattgtaataactggaaacggtggaattcagtggtcaagagggaaa cataaagaaagtgagacactgacagaacagggtttacagttatattgtgattttcctgat attattgatgtcagtattaaacaagcaaaccaagaaggctcaaatgaaagcagaattgta actattcataagcaagatggtaaaagtctggaaattgaacttagctcattaagtgaagct ttgtcttttgtgtctttaattgacggatattatagattaactgcagatgcacatcattat ctttgtaaagaagtagcacctccaatggtacttgaaaatatacaaagcaactgtcatggc ccaatttcaatggattttgctatcagtaaactgaagaaagcaggtaatcagactggactc tatgtacttcgatgcagtcctaaggattttaataaatattttctgacttttgctgttgag cgagaaaatgtcattgaatataagcactgtttgattacaaaaaatgagaatggagaatac aacctcagtggtactaagaagaacttcaataatcttaaagatcttttgaattgctaccag atggaaactgttcgctcagacagtatcatcttccagtttactaaatgctgtcccccaaag ccaaaagataaatcaaaccttctggtcttcagaaccaatggtatttctgatataccaacc tcaccaacattacagagacataataatgtgaaccaaatggtgttccacaaaatcagaaat gaagatttgatgtttaatgaaagccttggccaaggtacttttacaaaaatttttaaaggc gtaagaagggaagtaggagactacggtcaactgcatgaaacagaagttcttttaaaagtt ctggataaagcacatagaaactattcagagtctttctttgaagcagcaagcatgatgagc cagctttctcacaaacatctggttttaaattatggagtatgtgtctgtggagaggagaat attctggttcaggagtttgtaaaatttggatcactagatacatatctgaaaaagaataaa aattctataaatatattatggaaacttgaagtggctaaacagttggcgtgggccatgcat tttctagaagaaaaaacccttattcatggaaatgtgtgtgccaaaaatattcttcttatc agagaagaagacaggaagacaggaaatcctcctttcatcaaacttagtgatcctggcatt agtattacagttttgccaaaggacattctgcaggagagaataccatgggtaccacctgaa tgcattgaaaatcctaaaaatctaaacttagcaacagacaaatggagttttggtaccact ttgtgggaaatctgcagtggaggagataagcctctgagtgctttggattctcaaagaaag ctacaattttatgaagataggcaccaacttcctgcaccaaagtggacagaattagcaaat cttattaataattgtatggattatgaaccagattttagaccttctttcagagccatcatt cgagatcttaacagtttgtttactccagattatgaactattaacagaaaatgacatgtta ccaaatatgaggataggtgccctagggttttctggtgcttttgaagaccgagaccctaca caatttgaagagagacacttgaaatttctacagcaacttggcaagggtaattttgggagt gtggagatgtgccggtatgaccctctacaagacaatactggggaggtggtagctgttaaa aagctccagcacagtactgaagagcacctcagagactttgaaagggaaattgaaatcctt aaatccttgcagcatgacaacattgtaaagtacaagggagtgtgctacagtgctggccgg cgtaatctaagattaattatggaatatttaccatatggaagtttacgagagtatctccaa aaacataaagaacggatagatcataaaaaacttctgcagtacacatctcagatatgcaag ggcatggaatatcttggtacaaaaaggtatatccacagagatctggcaacaaggaatata ttggtggagaatgaaaacagagttaaaataggagattttggtttaaccaaagtcttgcca caagacaaagaatactacaaggtgaaagaacctggtgaaagtcctatattctggtatgca ccagaatcactgacagagagcaagttttctgtggcttcagatgtttggagctttggagtg gttctgtatgaacttttcacatatattgagaaaagtaaaagcccaccagcggaatttatg cgtatgattggcaatgacaaacaaggacagatgattgtgtttcatttgatagaacttctg aagaataatggaagattaccaagaccagatggatgcccagacgagatttatgtaatcatg acagaatgctggaacaataatgtaaatcagcgcccctctttcagagatctagcttttcga gttgatcaaataagggacaacatggctggatga

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