Camelus dromedarius (Arabian camel): 105103623
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Entry
105103623 CDS
T04642
Symbol
DOT1L
Name
(RefSeq) histone-lysine N-methyltransferase, H3 lysine-79 specific isoform X1
KO
K11427
[histone H3]-lysine79 N-trimethyltransferase [EC:
2.1.1.360
]
Organism
cdk
Camelus dromedarius (Arabian camel)
Pathway
cdk00310
Lysine degradation
cdk01100
Metabolic pathways
cdk05202
Transcriptional misregulation in cancer
Brite
KEGG Orthology (KO) [BR:
cdk00001
]
09100 Metabolism
09105 Amino acid metabolism
00310 Lysine degradation
105103623 (DOT1L)
09160 Human Diseases
09161 Cancer: overview
05202 Transcriptional misregulation in cancer
105103623 (DOT1L)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03036 Chromosome and associated proteins [BR:
cdk03036
]
105103623 (DOT1L)
Enzymes [BR:
cdk01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.1 Methyltransferases
2.1.1.360 [histone H3]-lysine79 N-trimethyltransferase
105103623 (DOT1L)
Chromosome and associated proteins [BR:
cdk03036
]
Eukaryotic type
Histone modification proteins
HMTs (histone methyltransferases)
HKMTs (histone lysine methyltransferases)
105103623 (DOT1L)
HMT complexes
Dot1-containing complex
105103623 (DOT1L)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
DOT1
Motif
Other DBs
NCBI-GeneID:
105103623
NCBI-ProteinID:
XP_031293903
LinkDB
All DBs
Position
22:complement(1625030..1674644)
Genome browser
AA seq
1658 aa
AA seq
DB search
MENYVLIDYDTKSFESMQRLCDKYNRAIDSIHQLWKGTTQPMKLNTRPSTGLLRHILQQV
YNHSVTDPEKLNNYEPFSPEVYGETSFDLVAQMIDEIKMTEDDLFVDLGSGVGQVVLQVA
AATNCKHHYGVEKADIPAKYAETMDREFRKWMKWYGKKHAEYTLERGDFLSEEWRERIAN
TSVIFVNNFAFGPEVDHQLKERFANMKEGGRIVSSKPFAPLNFRINSRNLSDIGTIMRVV
ELSPLKGSVSWTGKPVSYYLHTIDRTILENYFSSLKNPKLREEQEAARRRQQRDSKSSTT
TPTKAPADTPVDSGAEEEKAGAAAVKKPSPSKARKKKLNKKGRKMAGRKRGRPKKMSAAN
PERKPKKAQGALDLLHAQAVSRAASPSPQDAHRPPHSPFYQLPPSVQRHPPEQLLLAPTP
PALQKLLESFKIQYLQFLAYTKTPQYKANLQQLLDQEKEKNARLLGAAQQLFGHCQAQKE
EIKRLFQQKLDELGVKALTYNDLIQAQKEISAHNQQLREQTEQLEKGNRELRSQSLQLLR
ARCEELKLDWATLSLEKLLKEKQALRSQISEKQRRCLELQISIVELEKSQRQQELLQLKS
CVPPDDALSGQLRGKGALGRELEAEPGRLHLELDCAKLSLPHLSRVSPELSVNGHAAGYE
PCSALSRPSAKQDAHQCLACPLDREVVPCAPGHGGRPRLEKLPGLVLPDYARLSPAKLVL
RRHLSQDHAASGKVAAGEPHPRAEHAKENGLPYQSPGLANGIKLSPQDPRPPSPAALQMA
GEKGSEKGLKERAHGSSGEAITSLPVSIPLSTVQPSKLPVSIPLASVVLPSRAEKTRSTP
SPVPQAREASSTLEKQMSANAHSTGGSTAGSKSLALAPAGFAYTGSVAISGALAGSPPLA
PGVEPPALDESSSSGSLFAAMGSRSSTPQHPPLLAQPRSCGSGSPAPQLCTSPRLGPTQG
PLPDSKGDLPSEAGFSDPESEAKRRIVFTISAGASSSKQSPSSKHSPLPSGTRGDSGQSH
GQDSRKRGRRKRASAGTPSLSAGVSPKRRALPSVAGLFTQSSGSPLNLNSMVNNINQPLE
ITAISSPESSLKSSPVPYQDNDQPPVLKKEKPLSQTNGAHYSPLTSDEEQGSEDEPGSAR
IERKIATISLESKSPPKTLENGGGLAGRKAPPASEPVNSSKWKSTFSPISDLGLAKAADS
PLQASSALSHNSLFAFRPSLEEPGSADSKLATHPRKSFPAALPGAGGLSPSSHPASGFAL
GGGLAADLSLHSFSDGASLSHKAPEAAGLGAPLSFSGPRGKEGGASETGPFVNKRQLDGL
GPKGEGGLPSCGPPDKASLAHSKAGKARDREPDVKNGHNLFMAAAAAPPGGLLSSPGLAP
AASSAGSAAPATQAHRPFLGAFAPGPQFALGPMSLQANLGSSVLQSLFSSVPAAGLVHVS
SAATRLTNSHAMGSFSSGVAGGAVGGVFNHAVPPASAHPFGASFGSGAACRSATLSLTPL
QAVSSTPASSFQAPSSAEPRPPLPPPHLGRPPPGQPTLHAPPPPNAALPPPPALLPANSE
PVLLQNLAPLPANQAFLPASSAASLPPANTSLSIKLASLPHKASRPPFTVHRQPLPGLAL
AQAAPVIPQASSTGPPAVWVSLGMPPPYAARLAGVKPR
NT seq
4977 nt
NT seq
+upstream
nt +downstream
nt
atggagaattacgttctaattgactacgacaccaaaagcttcgaaagcatgcagaggctc
tgtgacaagtacaaccgggccatcgacagcatccaccagctgtggaaggggaccacacaa
cccatgaaactgaacacgcggccgtccaccgggctcctgcggcacatcctgcagcaggtc
tacaaccactcggtcactgaccccgagaagctgaacaactacgagcccttctccccggag
gtgtacggagagacctccttcgacctggtcgcccagatgatcgacgagatcaagatgacc
gaggatgacctgttcgtggacctgggcagcggagtgggccaggtcgtgctgcaggtcgcc
gcggccaccaactgcaaacatcactatggtgtcgagaaagcagacatcccagccaagtac
gcggagaccatggaccgcgagttcaggaagtggatgaaatggtatggaaaaaagcatgca
gaatacacactggagagaggcgatttcctctcggaggagtggagggagcggatcgccaac
acgagtgttatatttgtgaataactttgcctttggtcctgaggtggatcaccagctgaag
gagcggtttgcaaacatgaaggaaggtggcagaatcgtgtcctcgaagccctttgcgcct
ctgaacttcagaatcaacagtagaaacttgagcgacatcggcaccatcatgcgcgtcgtg
gagctctcgccgctgaagggctcggtgtcgtggacggggaagccggtctcctactacctg
cacaccattgaccgcaccatacttgaaaactatttttctagtctgaaaaatccaaaactc
agggaggagcaggaggccgcgaggcgccggcagcagcgagacagcaagagcagcacgacc
acgccgaccaaggcgcccgcggacaccccggtggactcgggcgctgaggaggagaaggcc
ggggcggctgctgtcaagaagccgtctccctctaaggcccgcaagaagaagttgaacaag
aagggccggaagatggcaggccgcaagcgcgggcgccccaagaagatgagcgccgccaac
cccgagcgcaagcccaagaaggcccagggcgccctggacctgctgcacgcccaggctgtg
tcgcgggcggcgtcgccctcgccgcaggatgcacacaggccacctcacagcccgttctac
cagctacctcccagcgtgcagcggcacccccccgagcagctgctgctggcacccacccca
cccgcactgcagaagctgctagaatccttcaagattcagtacttgcagttcctggcctac
acgaagacccctcagtacaaggccaacctgcagcagctgctggaccaggagaaggagaag
aatgcccggctgctgggtgctgcgcagcagctgttcggccactgccaggctcagaaggag
gagatcaagaggctcttccagcagaaactggacgagctgggagtgaaggcgctgacctac
aacgacctgatccaagcgcagaaggagatctcggctcacaaccagcagttgagggagcag
acggagcagctggagaagggcaaccgggagctgaggagccagagcctgcagctgctcagg
gctcggtgcgaggagctgaagctggactgggccacgttgtccctggagaagctgctgaag
gagaagcaggccctgaggagccagatctcagagaagcagaggcgctgcctggagctgcag
atcagcatcgtggagctggagaagagccagcggcagcaggagctcctgcaactcaagtcc
tgcgtgccacccgacgacgccctgtccgggcagctgcgcgggaagggcgccctgggccgg
gagctggaggccgagcccggccggctgcacctggagctggactgcgccaagctctccctg
ccacacttgagccgcgtgagcccagagctctccgtgaatggccacgcagccggctacgag
ccatgcagtgcgcttagccggccctcggccaagcaggacgcccaccagtgcctggcgtgc
cccctggaccgggaggtggtgccctgcgcccctggccacggcggccggccgaggctagag
aagctgcccggcctggtgctgcccgactacgcccggctctcccccgccaagctggtgctg
agacgccacctgagccaggaccatgcggccagcggcaaggtggccgctggcgagccgcac
ccgcgagctgagcacgccaaggagaacggcctcccgtaccagagccctggcctcgccaac
ggcatcaagctgagcccccaggaccctcggcccccctcccctgcggccttacagatggca
ggggagaagggcagtgagaagggactgaaggaacgtgcccacggcagcagcggggaggcc
atcaccagcctgcccgtcagcatcccgctcagcacggtgcagcctagcaaactgcccgtc
agcatccccctggccagcgtggtgctgcccagccgcgccgagaagacgagaagcaccccc
agccctgtgccgcaggcccgggaggcctcgtccacgctggaaaagcagatgagtgctaac
gcccacagcaccgggggcagcactgctgggagcaaaagcctcgccctggcccctgcaggc
tttgcgtacaccggctcggtggccatcagtggggccctggcaggcagcccgcccctcgcc
cctggagttgagcccccagccttggacgagtcttctagctccggaagcctatttgcggca
atggggtcccgcagctccaccccgcagcacccccccttgctggcgcagccccgcagctgc
ggctccggctcgcctgccccccagctttgcaccagcccccggcttggccccacccagggc
ccgctccccgacagcaaaggggacctcccctccgaggctggcttctcggaccccgagagc
gaagccaagaggaggatcgtcttcaccatctcggctggtgccagcagctccaagcagtcg
ccttccagcaagcacagccctctgccctcaggcacccgcggggacagcggccagagccac
gggcaggacagccgcaagcggggcaggaggaagcgggcctcggcagggacccccagcctg
agcgcaggcgtgtcccccaagcgccgggccctgccgtccgttgctggcctcttcacccag
tcttcggggtcccccctgaatctcaactccatggtcaacaacattaaccagcctttggag
attacggccatctcgtcccccgagagctccctgaagagctccccagtcccttaccaggac
aatgaccagccgccggtgctcaagaaggagaagcccctgagtcagaccaatggtgcccac
tactccccactgacctcggacgaggagcagggctccgaggacgagcccggcagcgccaga
attgagagaaaaattgcaacaatctccttagaaagcaaatctcctcccaaaaccttggaa
aacggtggcggcctggcgggaaggaaggcgccaccagccagcgagccagtcaatagcagc
aagtggaagtccaccttctcgcccatctccgacctcggcctggccaaggcggccgacagc
ccgctgcaggccagctccgctctgagccacaactccctgttcgctttccggcccagcctg
gaggagcctggctcggccgactccaagctggccacccaccccaggaagagcttcccagcc
gccctgccgggggcaggcgggctgagccccagcagccatcctgccagtggcttcgcgctg
ggcgggggcctggcggccgacctcagtttacacagcttcagtgatggtgcttctctctcc
cacaaggcccctgaggcggctggtctgggcgcccccctgagcttttctggcccgcggggc
aaggagggcggtgcctcggaaactggccccttcgtgaacaagaggcagctggacggactg
ggcccgaagggtgaggggggcctgccctcatgcgggcccccggacaaggcctcattggcc
cacagcaaggcgggcaaggctcgtgaccgcgagcctgacgtcaagaatggccacaacctg
ttcatggccgcggccgccgcgccccccgggggcctcctcagcagcccgggcctcgccccg
gcagcatcctcggcgggcagtgcggccccggccacccaggctcaccgccccttcctgggc
gccttcgcccccggcccgcagttcgcgctgggccccatgtccctgcaggccaacctgggc
tcatccgtgctgcagtctctgttcagctccgtgcccgccgccggcctggtgcacgtctcg
tccgccgccaccagactgaccaactcgcacgccatgggcagcttctcctccggggtggcc
ggcggcgcagttggaggtgtctttaaccacgcggtgcctcccgcctccgctcatccgttt
ggagccagtttcggcagtggggctgcgtgtcgcagcgccacgctgagcttaaccccgctg
caggcggtgtccagcaccccagcctcttcctttcaggccccgtcctctgcggagccgagg
ccgcccctgccccctccgcacctgggccggccccctccggggcagcccaccctccacgca
cccccgcctcctaacgccgccttgcctcctccccccgcgctgctcccggctaactctgag
cctgtgcttctgcagaacctcgcgcccctcccggctaaccaagctttcttacctgcttcc
tctgctgcctctctgccacctgctaacacctctctatccatcaagctcgcctccctcccg
cacaaggcgtcccgcccccccttcacggtgcaccgccagcccctgcccgggctggccctg
gcccaggccgcgcccgtgatcccgcaggccagctccacggggccacccgccgtgtgggtt
tcccttggcatgccgcctccgtatgccgcgcgccttgcgggggttaagccgcgataa
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