Clostridioides difficile R20291: CDR20291_0645
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Entry
CDR20291_0645 CDS
T00998
Symbol
fhs
Name
(GenBank) formate--tetrahydrofolate ligase
KO
K01938
formate--tetrahydrofolate ligase [EC:
6.3.4.3
]
Organism
cdl
Clostridioides difficile R20291
Pathway
cdl00670
One carbon pool by folate
cdl00720
Other carbon fixation pathways
cdl01100
Metabolic pathways
cdl01120
Microbial metabolism in diverse environments
cdl01200
Carbon metabolism
cdl01240
Biosynthesis of cofactors
Module
cdl_M00140
C1-unit interconversion, prokaryotes
cdl_M00377
Reductive acetyl-CoA pathway (Wood-Ljungdahl pathway)
cdl_M00618
Acetogen
Brite
KEGG Orthology (KO) [BR:
cdl00001
]
09100 Metabolism
09102 Energy metabolism
00720 Other carbon fixation pathways
CDR20291_0645 (fhs)
09108 Metabolism of cofactors and vitamins
00670 One carbon pool by folate
CDR20291_0645 (fhs)
Enzymes [BR:
cdl01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.4 Other carbon-nitrogen ligases
6.3.4.3 formate---tetrahydrofolate ligase
CDR20291_0645 (fhs)
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Gene cluster
GFIT
Motif
Pfam:
FTHFS
CbiA
AAA_31
Motif
Other DBs
NCBI-ProteinID:
CBE02588
UniProt:
A0A9R0BIK0
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All DBs
Position
803133..804809
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AA seq
558 aa
AA seq
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MGFKSDIEIAQEAKPQDIREVAKKLGLGEDDVELYGKYKAKVDYNLLKRETGKKAKLILT
TAINPTPAGEGKTTTTIGVADAFAKLDKNVLVALREPSLGPVFGVKGGAAGGGYAQVVPM
EDINLHFTGDFHAIGAANNLLAAMLDNHIHQGNALRIDPKKITWRRCVDMNDRQLRNIVD
GMGKKGDGAVRQDGFDITVASEIMAAFCLASDISDLKERLGNIIVGYSYEGEPVTARQLK
ANGAMAALLKDALKPNLVQTLEGTPSFVHGGPFANIAHGCNSVIATRMAMHFADYVITEA
GFGADLGAEKFLDIKCRMANLKPDAVIIVATVRALKYNGGVAKADLNNENLEALEKGLPN
LLKHVENITQVYGLPAVVAINRFPLDTEAELKLVEDKCKELGVNVALSEVWAKGGEGGIA
VAKEVLRLLDEEENNFRFCYEDDLSIKDKINAIATKIYGADGVDYTPEADKEIANLEKLG
FTKVPVCMAKTQYSLTDDQTKLGRPTGFRITVRQATISAGAGFIVALTGEIMKMPGLPKV
PAAEKIDVDENGVIAGLF
NT seq
1677 nt
NT seq
+upstream
nt +downstream
nt
atgggatttaaatctgacattgaaatagctcaagaagctaagcctcaagatattagagag
gttgcaaaaaaattaggactaggtgaagatgatgtagaactttatggtaaatacaaagca
aaagttgactacaatctactaaaaagagagactggtaaaaaagctaagttaatactaact
acagctataaatccaactccagcaggtgaaggaaaaactactactactataggtgttgct
gatgcatttgctaaactagacaaaaatgtattagttgctttaagagaaccatctctagga
ccagtatttggtgttaaaggtggagcagctggtggaggatatgcacaagttgttcctatg
gaagatataaacttacacttcacaggagattttcacgctataggagctgctaacaatctt
ttagctgctatgcttgataaccatattcaccaaggaaatgcacttagaatagaccctaag
aaaataacttggagaagatgtgtggacatgaacgatagacaacttagaaatatcgttgat
ggtatgggtaaaaaaggtgatggagcagttagacaagatggattcgatataactgttgct
tctgaaataatggcagcgttctgtttggcaagtgatatatctgatttaaaagaaagatta
ggaaacataatagttggatacagctatgaaggtgaacctgtaacagctagacaattaaaa
gctaatggtgctatggctgcattattaaaagatgctttaaaaccaaacctagttcaaact
cttgaaggaacaccatcatttgtacacggtggaccattcgcaaatatagctcatggatgt
aactctgttatagctacaagaatggctatgcactttgcagactatgtaataactgaggct
ggtttcggtgctgaccttggagcagaaaaattcttagatataaaatgtagaatggcaaac
ttaaaaccagatgctgttataatagttgctactgtaagagcattaaaatacaatggtgga
gttgctaaagcagacttaaataacgaaaacctagaagctcttgaaaaaggacttccaaac
ttattaaaacatgttgaaaacataactcaagtatatggattaccagcagttgttgcaatc
aatagattcccacttgatactgaagctgaacttaaacttgttgaagacaagtgtaaggaa
ttaggtgttaatgttgctctttctgaagtatgggcaaaaggtggagaaggtggaattgca
gtagctaaagaagttttaagattattggatgaagaagaaaataactttagattctgctat
gaagatgatttatctataaaagacaagataaatgctatagctactaagatttatggagca
gatggtgtagattatactcctgaagctgataaggaaatagctaacttagaaaaacttgga
tttactaaagttccagtatgtatggctaagactcaatattctttaactgatgaccaaact
aaattaggtagaccaacaggatttagaataactgtaagacaagcaacaatttcagcagga
gctggatttatagttgcacttactggagaaataatgaagatgccaggattaccaaaagtt
ccagcagcagaaaaaatagatgttgatgaaaatggagtaatagctggattattctaa
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