Corynebacterium diphtheriae 241: CD241_0341
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Entry
CD241_0341 CDS
T01687
Symbol
hemD
Name
(GenBank) uroporphyrin-III C-methyltransferase / uroporphyrinogen-III synthase
KO
K13542
uroporphyrinogen III methyltransferase / synthase [EC:
2.1.1.107
4.2.1.75
]
Organism
cdp
Corynebacterium diphtheriae 241
Pathway
cdp00860
Porphyrin metabolism
cdp01100
Metabolic pathways
cdp01110
Biosynthesis of secondary metabolites
cdp01120
Microbial metabolism in diverse environments
cdp01240
Biosynthesis of cofactors
Module
cdp_M00926
Heme biosynthesis, bacteria, glutamyl-tRNA => coproporphyrin III => heme
Brite
KEGG Orthology (KO) [BR:
cdp00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00860 Porphyrin metabolism
CD241_0341 (hemD)
Enzymes [BR:
cdp01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.1 Methyltransferases
2.1.1.107 uroporphyrinogen-III C-methyltransferase
CD241_0341 (hemD)
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.75 uroporphyrinogen-III synthase
CD241_0341 (hemD)
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
HEM4
TP_methylase
ECH_1
Motif
Other DBs
NCBI-ProteinID:
AEX43408
LinkDB
All DBs
Position
325422..327092
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AA seq
556 aa
AA seq
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MRLIMKPEHSTRGRVIFVGAGPGNPDLLTVRAREVLGSTANAVVDSTVGVGIRAVIAEHL
EVPQAKLDAAEAEYERMCAAAKRRKPPRPDAPTAAEITEVSADASVDEVMAVLLPLLDEG
DVIRLVQGNPLADSRALDEITAVTQVGADFQIVPGMSLPAAVPAFAGITLGDSYTKTTVS
EDTNWDQLATAPLPLILQASKDDLLIIATELKDRKLPASTPVTVTMNGTTRLQRSFDVTL
KTMKSLVKQELDGTLVVTVGVSDRSTFSWWESRALFGWRVLVPRAKDQAGPMSSRIAAYG
AIAQEVPTISVEPPRNPAQLERAIKGIVEGRYQWVVFTSANAVKAVREKIVSFGLDSRAF
AGVHIAAVGAKTAAAIREFGITPELIPPRKEHNAAGMVSVFPNYVEGLDPVGRVLLPRAD
IATDVLVDGLVNLGWEVDDVVAYRTVRAAPPSAEVRDMIKSGDFDAVCFTSASTVRNLVG
IAGKPHARTIIACIGPMTAAEAEKQGLRVDVIPEVANVPALVDALAEHVEKLRAAGELPP
PRKKRRARRKSKEGAV
NT seq
1671 nt
NT seq
+upstream
nt +downstream
nt
atgcgattaatcatgaagcccgagcactcaacgcgaggacgtgtcatcttcgtcggcgcc
ggtcccggcaacccagatcttttgacggttcgagcccgcgaggtgctgggctccacagcc
aatgcagtggtggattccactgttggcgtaggtattcgcgcagttattgctgaacatctt
gaggtgccgcaggccaagcttgatgcagctgaggctgagtatgagcgcatgtgtgcggct
gcgaagcgtcgtaagcctccgcgtcccgacgcccccaccgccgcggaaatcactgaggtg
tccgctgatgcgagcgtcgatgaagtgatggcggtgctgttgcctttgctagacgaaggc
gatgtgatccgcctagtgcagggtaacccgttggcggattcccgcgcgttagatgagatt
acggctgttacacaggtgggcgcggatttccagattgtgccaggtatgtcgttgccggct
gcggttcctgctttcgcgggtattacgttgggtgattcttataccaagaccacggtgagt
gaggatactaactgggatcagttggcaaccgccccgctgccgttgattttgcaggcgagt
aaagacgacttgctgattatcgctacggagttgaaggatcgcaaactgccggcgagcact
ccggtgacggtgacgatgaatggcacgacgcgtttgcagcggagctttgacgtgacgctt
aaaactatgaagtcgttggtcaaacaggagctcgatggcactcttgtggtcacagtgggt
gtatcggatcgcagcacgttttcgtggtgggaaagccgcgcgttgtttggctggcgggtg
ttggttcctcgtgcgaaggatcaagctggtccgatgagcagccgaatcgccgcctatggt
gctattgcccaagaggttcccactatttctgtggagccgccgcgtaatcctgcgcagttg
gagcgtgcgattaagggcattgtggagggacgctaccagtgggtggtgtttaccagcgcg
aatgctgttaaggcagtgcgtgagaagatcgtatcgtttggtttggattctcgcgcgttc
gcgggggtgcatatcgctgcggtgggggctaagactgcggcggcgattcgtgagtttggc
attactcctgagctaattccgccacgtaaggagcataatgctgcgggtatggtgtcggtt
ttccctaattatgtggagggcttggacccggtaggtcgggtgttgctgccgcgggctgat
attgccactgatgtgctggttgatggtttggtcaaccttggctgggaagttgatgatgtg
gtggcgtatcgtacggtgcgtgccgcgccgccgagtgcggaagtccgcgacatgattaag
tccggcgattttgatgcggtgtgttttacctctgcgtcgacggtgcgcaatttggtgggt
attgcgggtaagccgcatgcacgcacgatcattgcatgtattgggccgatgaccgctgcg
gaggcagagaagcaagggctgcgtgtcgacgtcatccccgaggtggctaacgttccggct
cttgtggatgcgctggcggagcatgtggagaaactgcgtgctgcgggtgagttgccgccg
ccgcgtaagaagcgtcgggcccgtcgcaaatctaaggaaggtgctgtatga
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