Corynebacterium diphtheriae HC03: CDHC03_2023
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Entry
CDHC03_2023 CDS
T01695
Symbol
purL
Name
(GenBank) phosphoribosylformylglycinamidine synthase
KO
K01952
phosphoribosylformylglycinamidine synthase [EC:
6.3.5.3
]
Organism
cdr
Corynebacterium diphtheriae HC03
Pathway
cdr00230
Purine metabolism
cdr01100
Metabolic pathways
cdr01110
Biosynthesis of secondary metabolites
Module
cdr_M00048
De novo purine biosynthesis, PRPP + glutamine => IMP
Brite
KEGG Orthology (KO) [BR:
cdr00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
CDHC03_2023 (purL)
Enzymes [BR:
cdr01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.5 Carbon-nitrogen ligases with glutamine as amido-N-donor
6.3.5.3 phosphoribosylformylglycinamidine synthase
CDHC03_2023 (purL)
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Ortholog
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Gene cluster
GFIT
Motif
Pfam:
GATase_5
AIRS_C
FGAR-AT_linker
AIRS
DJ-1_PfpI
GATase_3
Motif
Other DBs
NCBI-ProteinID:
AEX79748
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Position
2180958..2184674
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AA seq
1238 aa
AA seq
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MDARLAIRRSPNFRDEERALLRSLNNLEGAPLTDVQIINVYDVFDATEADITALTNSIVS
DPKVDTVLTTAELDTIVEQAPAHLAVEPLPGQYDQRADAAEQALRLLNPHTNARVTSGEL
YIFSDLTEEAFANIRDYLINPVEAGEKNLDVLRAPSMGDIAPLKQYPDFLELDEAGLSAL
LASEGMAMSLADLKLIQEYFRTEGRTPTEVELAALDTYWSDHCRHTTFNTELTEITNSSS
RYGAQLDRALKRYDELREANGRAHKPRTLMDLGTIMGRELRRNGTMTDQEISEEINACSV
YVDVDTPDGDKSWLLMFKNETHNHPTEIEPFGGASTCLGGAIRDPLSGRSWVYQAMRISG
AGDINTPRTETIDGKLPQADISARATHGYSSYGNQIGLATTSVRELIHPGYVAKRMELGA
VVAAAPQENVKRLEPQPGDVVIILGGRTGRDGVGGATGSSKAHDEESLARSGAEVQKGNP
VNERKIQRLFRRPEIAQMIVRCNDFGAGGVSVAVGELTDSIDIHLDRVPLKYAGLNAREI
AISESQERMAVVVRPEDAAAFIEAAATENIEAVELATVTDSGRLRMFLGKDLVLDLSREF
LETNGAARSQSVEMRDAGDVEKPAQPATILESLTRHGSQEGMVEQFDATVGRSTVLMPYG
GRTQKTDELASVQTFPVPGGSHTASVMTYGFSPELADVSPYLMGSYSVVEALSRLVATGA
NARGAWLSVQEYFQRLDQKPELWGEVTQALLGLLEAQDAFEVAAIGGKDSMSGTYGDDLH
VPATLVTFAVATMDARRTLSAAIPSGEFDVYHLAHTPLETGEANYEQLHANFDAFHELAA
TGTLSAASPIIPGGLGATIVNMLLGNELGFQGTATTNAALGGLVFAVPAGTAVELADAQL
IGHTNPSGEITFGEETFTIAQALDTLERDYREVYPLNVTTADVEALPDFATALPKADTDS
EEANASAGDKAVHVLLPVFPGTNSEYDMAEAFEAAGATTEFHIIRNFNSEMLAADTEAFI
TKLQSANILAFSGGFSLGDEPDGSAKFMAAFLRSDAVAAAVKDFVAGDGLVLGICNGFQA
LVKSGFLPYGDPAKMTAESPTLAHNRQLRHVSRIATTRVSSVASPWLSTFTPGQQHLMPV
SHGEGRFVVSETEAQALFSAGQVAFQYVDTEGTPTMEAPANPNGSNYAIEGIISPDGRIL
GKMGHPERFRDGLMCNIPGMEVQDIFANAVNYCRKSQR
NT seq
3717 nt
NT seq
+upstream
nt +downstream
nt
atggacgcgcgtcttgccattcgccgctcacccaacttccgcgacgaggagcgcgcgcta
ctgcgttccctcaacaacctagaaggcgcccccctcaccgacgtccagatcatcaatgtc
tacgacgtcttcgacgccaccgaagcagacatcaccgccctaacaaactccatagtcagc
gaccccaaggtggacaccgtactcactacagctgagctcgacaccatcgtcgaacaagca
ccagctcatctcgcggtcgaaccactacctggccaatacgaccagcgcgccgacgcagcc
gaacaagcactacgactgctcaacccccacaccaacgcacgtgtaacctccggcgagctt
tatatcttcagcgacctaaccgaagaggcattcgccaacatccgcgactacctgatcaac
cccgtcgaagcaggcgagaaaaacctcgatgtactgcgcgcaccatccatgggcgacatc
gccccactcaagcaatacccagatttccttgagctcgacgaagctggcttgagcgcattg
ctggccagcgaaggcatggccatgagcttggcggacctgaagcttattcaggaatacttc
cgcaccgaaggccgcacccccaccgaggtggaactggcagcactggacacctactggtcc
gatcactgccgccacaccacctttaacaccgagctgacagagatcaccaactccagcagt
cgttacggtgcacagctcgaccgcgcactgaagcgttacgacgaactccgcgaagccaac
ggtcgcgcccataagccacgcaccctcatggacttgggcaccatcatgggccgtgagctg
cgtcgcaacggaaccatgaccgatcaagagatcagcgaagaaatcaacgcctgctccgta
tacgttgacgtggacaccccagatggcgacaagtcttggctgctgatgttcaaaaacgaa
acccacaaccaccccaccgaaatcgaaccattcggtggcgcatccacctgcctcggtggc
gcaatccgcgacccactatccggtcgctcctgggtttaccaagcaatgcgcatctccggc
gccggtgacatcaacaccccacgcaccgaaacgatcgacggcaaactcccgcaggcagac
atcagtgcccgcgcaacccacggctactccagctacggcaaccagatcggtctggcaacc
accagcgtccgcgaactgattcacccaggttacgtcgccaagcgcatggaactcggcgcc
gttgtggcagccgcaccacaagaaaacgtcaagcgcctagagccacaaccaggcgacgta
gtgatcatcctcggtggccgcaccggacgcgacggcgtgggcggagccaccggctcctcc
aaagcacacgacgaagaatccttggcacgctcgggtgcagaagtccaaaagggcaacccc
gtcaacgaacgcaagatccaacgcctgttccgccgaccagaaatcgcccaaatgatcgtg
cgctgcaatgacttcggcgcaggtggcgtgtccgtcgcagtcggcgaactcaccgacagc
atcgacatccacctcgatcgcgtaccactgaaatacgccggcctcaacgcccgcgaaatc
gccatctccgagtcccaggaacgcatggcagtcgtcgtgcgcccagaagacgcagccgcc
ttcattgaagcagccgcaaccgaaaacatcgaggcagtagagctcgccaccgtcaccgac
agcggacgcctacgcatgttcctcggcaaggacctagtcctcgacctctcccgcgaattc
ctcgaaaccaacggcgcagcacgctcccaaagcgtagaaatgcgcgatgcaggagacgtc
gaaaagcctgctcagccagcaaccatcctcgaatccttgacccgccacggctcccaagaa
ggcatggtcgaacaattcgacgccaccgtcggacgctccaccgtactcatgccttacggc
ggccgcacccaaaaaaccgacgaactcgcatccgtacaaaccttcccagtaccaggcgga
tcccacaccgcatcggtcatgacctacggattcagcccagagctcgccgacgtctccccc
tacctcatgggctcctactccgtcgtcgaagcactcagccgcctcgtcgccaccggtgcc
aacgcacgcggcgcatggctgtccgtccaagaatacttccagcgcctcgaccaaaaacca
gaactctggggcgaagtaacccaggcactcctgggccttcttgaagcacaagacgccttc
gaagtagctgccatcggcggcaaggactccatgagcggcacatacggcgatgacctgcac
gttcccgcaacgctggtcaccttcgcagtcgcaaccatggacgcacgacgcaccctcagc
gccgccatcccaagcggcgaattcgacgtctaccacctcgcccacaccccgctggaaacc
ggcgaagccaactacgagcaactccacgccaacttcgacgccttccatgagctcgccgcc
accggcaccctctcggcagcctcccccatcatcccaggtgggctcggcgccaccatcgtg
aacatgctgctcggcaacgaactcggattccagggcaccgccaccaccaacgcagccctc
ggtggactcgtattcgcggtcccagccggcaccgcagtcgagcttgccgacgcccaactc
atcggtcacaccaacccatccggcgagatcaccttcggcgaagaaaccttcaccatcgcg
caagcactcgacacactagagcgcgactaccgcgaggtctaccccctcaacgtgaccacc
gcagacgtagaggccctcccagattttgctaccgctctacccaaggcggacaccgattct
gaagaagccaacgcctccgccggtgacaaagccgtacacgtgttgctgccagtatttcca
ggtactaactccgaatacgacatggccgaggccttcgaggcagcaggtgccaccaccgaa
ttccacatcatccgaaacttcaactcggagatgctggctgctgacacagaagcattcatc
accaagctgcaatccgccaacatcctggcattctccggcggattctccctcggcgacgaa
ccagacggctccgcgaaattcatggcagccttcctacgctccgacgccgtagccgcagcg
gtcaaggacttcgtggccggcgacgggctcgtcctcggaatctgcaacggcttccaagca
ctggtcaagagcggattcctgccatacggcgaccccgccaagatgaccgcagaatcccca
acgttggcacacaaccgccaactgcgacacgtctcacgcatcgccaccactcgcgtcagc
tccgtagcctccccatggctgagcacctttaccccaggccagcagcacctcatgccggtt
tcccacggcgaaggccgcttcgtggtatccgaaacggaagcccaagcactctttagcgca
ggtcaggtagcattccagtatgtggataccgagggcacccccaccatggaagcacctgcg
aaccccaacggatccaactacgccatcgagggcatcatctccccagatggtcgcatcctt
ggcaagatgggacaccccgagcgcttccgcgacggcctcatgtgcaacattcctggtatg
gaggtccaagacatctttgctaacgcggtgaactactgccgtaagagtcaacgctag
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