Corynebacterium diphtheriae HC01: CDHC01_1539
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Entry
CDHC01_1539 CDS
T01693
Symbol
murF
Name
(GenBank) UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diamino pimelate-D-alanyl-D-alanyl ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
cdt
Corynebacterium diphtheriae HC01
Pathway
cdt00300
Lysine biosynthesis
cdt00550
Peptidoglycan biosynthesis
cdt01100
Metabolic pathways
cdt01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
cdt00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
CDHC01_1539 (murF)
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
CDHC01_1539 (murF)
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
CDHC01_1539 (murF)
Enzymes [BR:
cdt01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
CDHC01_1539 (murF)
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Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
Motif
Other DBs
NCBI-ProteinID:
AEX74783
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Position
complement(1618261..1619751)
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AA seq
496 aa
AA seq
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MIDLTVEQIARIVGGTLTQGTDPETVVTGPVEFDSRKVSEGSLFVALAGARVDGHDFVPA
ALESGAAAALVAHPVKIDSGLAPAIVVPPATGQQQSANSYATEHDEDGSVAAVLQGMGLI
ARRVIDTLTAQGLTVMGVTGSAGKTSTKDMLASILSNQAPTVAPPGSFNNEIGHPYTALR
CTEQTRYLVAEMSARGIGHIAHLAQIAPPKIGVVLNVGTAHLGEFGSREVIAQAKGELVE
ALPHDGVAVLNADDDLVAGMRTRTDAKVITFSANSQDADVYATDIELDDYARARFTLHIG
EAENVVTLRVAGQHQVSNALAATAAAYAAGIAIDDIAEALSNHLGASAHRMALMHRSDGA
TIIDDAYNANTESMRAGLTALSTTAHNKSHKGEASHAWAVLGPMSELGEESVAAHEEIGR
LLGELNVHGLIVVGDSADSLALADGARRSNVTTLMARDTAEAADLLDQNMGSADVALVKA
SNAYRLWETAEILASK
NT seq
1491 nt
NT seq
+upstream
nt +downstream
nt
atgattgatctgactgttgaacagatcgcacgtatcgtgggtggaacactcacacaaggc
actgatccagaaaccgtagtgacgggacctgtggaatttgactcgcgcaaggtatcggaa
ggttctttgtttgtggcgttggccggagcgcgtgtcgacggccatgatttcgtgccagct
gcgttagaaagtggcgctgcagcagcattggtagcgcatcctgtgaagatcgattctgga
ttagcgcccgctattgtggtgccacctgcgactggtcaacagcaatcggccaacagttac
gcaactgaacatgatgaagacggttcagttgcggctgttctccaaggtatgggacttatt
gcgcgaagagtcatcgatacgttgactgctcaggggttaaccgtcatgggtgttactggt
tcggcagggaaaacctcgaccaaagacatgttggcgtcaattctgagtaatcaggcccct
acagtggcccctcctggatctttcaataacgagatcgggcatccatatacagctttacgc
tgtaccgaacagacccgttatctagtagcggagatgtctgcccgcggcattggccacata
gcacatctagcacagattgcccctcctaaaatcggtgttgtgctcaatgttggcaccgcg
catctaggcgaatttggttcgcgcgaagttattgctcaagccaaaggcgaattagtggag
gcacttcctcacgacggtgtggctgtacttaatgcagatgatgatctcgttgcaggcatg
cgtactcgaactgatgcgaaggtgatcactttttccgcgaattcgcaggacgcggatgtt
tatgccaccgatattgaacttgacgattatgcgcgtgctcgttttaccctccacattggc
gaagcggagaacgtcgtaacgcttcgagttgctggccagcatcaagtttccaatgcactg
gcagctacagcggcggcatatgcggcaggcatagccattgacgatattgccgaagcattg
agtaaccaccttggcgcttctgcgcaccgtatggctcttatgcaccgtagcgatggcgca
accatcattgatgatgcttataacgccaacactgagtcgatgcgtgccggtcttacggcg
ctttccactactgctcacaacaagtcgcacaagggcgaagcctcgcacgcgtgggcagtg
ttgggtcccatgagtgagctaggggaggagtcggttgcggcacacgaagagattggcagg
ctcctcggtgagttgaatgtgcatggattaatcgttgtcggagactctgctgattctttg
gcattggcagatggagcccgacgcagcaatgtgactacacttatggctcgcgataccgca
gaagcagcagatctccttgatcagaatatgggttctgcagacgtggctcttgtaaaagca
tctaatgcatatcgtttgtgggaaaccgcagagattttagcttcaaaataa
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