Corynebacterium diphtheriae HC01: CDHC01_2022
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Entry
CDHC01_2022 CDS
T01693
Symbol
purL
Name
(GenBank) phosphoribosylformylglycinamidine synthase
KO
K01952
phosphoribosylformylglycinamidine synthase [EC:
6.3.5.3
]
Organism
cdt
Corynebacterium diphtheriae HC01
Pathway
cdt00230
Purine metabolism
cdt01100
Metabolic pathways
cdt01110
Biosynthesis of secondary metabolites
Module
cdt_M00048
De novo purine biosynthesis, PRPP + glutamine => IMP
Brite
KEGG Orthology (KO) [BR:
cdt00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
CDHC01_2022 (purL)
Enzymes [BR:
cdt01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.5 Carbon-nitrogen ligases with glutamine as amido-N-donor
6.3.5.3 phosphoribosylformylglycinamidine synthase
CDHC01_2022 (purL)
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Gene cluster
GFIT
Motif
Pfam:
GATase_5
AIRS_C
FGAR-AT_linker
AIRS
DJ-1_PfpI
GATase_3
Motif
Other DBs
NCBI-ProteinID:
AEX75263
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All DBs
Position
2145040..2148756
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AA seq
1238 aa
AA seq
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MDARLAIRRSPNFRDEERALLRSLNNLEGAPLTDVQIINVYDVFDATEADITALTNSIVS
DPKVDTVLTTAELDTIVEQAPAHLAVEPLPGQYDQRADAAEQALRLLNPHTNARVTSGEL
YIFSDLTEEAFANIRDYLINPVEAGEKNLDVLRAPSMGDIAPLKQYPDFLELDEAGLSAL
LASEGMAMSLADLKLIQEYFRTEGRTPTEVELAALDTYWSDHCRHTTFNTELTEITNSSS
RYGAQLDRALKRYDELREANGRAHKPRTLMDLGTIMGRELRRNGTMTDQEVSEEINACSV
YVDVDTPEGDKPWLLMFKNETHNHPTEIEPFGGASTCLGGAIRDPLSGRSWVYQAMRISG
AGDINTPRTETIDGKLPQADISARATHGYSSYGNQIGLATTSVRELIHPGYVAKRMELGA
VVAAAPQENVKRLEPQPGDVVIILGGRTGRDGVGGATGSSKAHDEESLARSGAEVQKGNP
VNERKIQRLFRRPEIAQMIVRCNDFGAGGVSVAVGELTDSIDIHLDRVPLKYAGLNAREI
AISESQERMAVVVRPEDAAAFIEAAATENIEAVELATVTDSGRLRMFLGEDVVLDLSREF
LETNGAARSQSVEMRDAGDVEKPAQPATILESLTRHGSQEGMVEQFDATVGRSTVLMPYG
GRTQKTDELASVQTFPVPGGSHTASVMTYGFSPELADVSPYLMGSYSVVEALSRLVATGA
NARGAWLSVQEYFQRLDQKPELWGEVTQALLGLLEAQDAFEVAAIGGKDSMSGTYGDDLH
VPATLVTFAVATMDARRTLSAAIPSGEFDVYHLAHTPLETGEANYEQLRANFDAFHELAA
TGTLSAASPIIPGGLGATIVNMLLGNELGFQGTATTNAALGGLVFAVPAGTAVELADAQL
IGHTNPSGKIAFGEETFTIAQALDTLERDYREVYPLNVTTADVEALPEFATALPTADSDS
EEANASAGDKAVHVLLPVFPGTNSEYDMAEAFDAAGATTEFHIIRNLNSEMLAADTEAFI
TKLQSANILAFSGGFSLGDEPDGSAKFMAAFLRSDAVAAAVKDFVARDGLVLGICNGFQA
LVKSGFLPYGDPAKMTAESPTLAHNLQLRHVSRIATTRVSSVASPWLSTFTPDQQHLMPV
SHGEGRFVVSETEAQALFSAGQVAFQYVDTEGTPTMEAPANPNGSNYAIEGIISPDGRIL
GKMGHPERFRDGLMRNIPGMEVQDIFANAVNYCRKSQH
NT seq
3717 nt
NT seq
+upstream
nt +downstream
nt
atggacgcgcgtcttgccattcgccgctcacccaacttccgcgacgaggagcgcgcgcta
ctgcgttccctcaacaacctagaaggcgcccccctcaccgacgtccagatcatcaatgtc
tacgacgtcttcgacgccaccgaagcagacatcaccgccctaacaaactccatagtcagc
gaccccaaggtggacaccgtactcactacagctgagctcgacaccatcgtcgaacaagca
ccagctcatctcgcggtcgaaccactacctggccaatacgaccagcgcgccgacgcagcc
gaacaagcactacgactgctcaacccccacaccaacgcacgtgtaacctccggcgagctt
tatatcttcagcgacctaaccgaagaggcattcgccaacatccgcgactacctgatcaac
cccgtcgaagcaggcgagaaaaacctcgatgtactgcgcgcaccatccatgggcgacatc
gccccactcaagcaatacccagatttccttgagctcgacgaagctggcttgagcgcattg
ctggccagcgaaggcatggccatgagcttggcggacctgaagcttattcaggaatacttc
cgcaccgaaggccgcacccccaccgaggtggaactggcagcactggacacctactggtcc
gatcactgccgccacaccacctttaacaccgagctgacagagatcaccaactccagcagt
cgttacggtgctcagctcgaccgcgcactgaagcgttacgacgaactccgcgaagccaac
ggtcgcgcccataagccacgcaccctcatggacttgggcaccatcatgggccgtgagctg
cgtcgcaacggaaccatgaccgatcaagaagtcagcgaagaaatcaacgcctgctctgta
tacgttgacgtggacaccccagaaggcgacaagccttggctgttgatgttcaaaaacgaa
acccacaaccaccccaccgaaatcgaaccattcggtggcgcatccacctgcctcggtggc
gcaatccgcgacccactatccggtcgctcttgggtttaccaagcaatgcgcatctccggc
gccggtgacatcaacaccccacgcaccgaaacgatcgacggcaaactgccccaggcagac
atcagtgcccgcgcaacccacggctactccagctacggcaaccagatcggtctggcaacc
accagcgtccgcgaactgattcacccaggttacgtcgccaagcgcatggaactcggcgcc
gttgtggcagccgcaccacaagaaaacgtcaagcgcctagagccacaaccaggcgacgta
gtgatcatcctcggtggccgcaccggacgcgacggcgtgggcggagccaccggctcctcc
aaggcacacgacgaagaatccttggcacgctcgggtgcagaagtccaaaaaggcaacccc
gtcaacgaacgcaagatccaacgcctgttccgccgaccagaaatcgcccaaatgatcgtg
cgctgcaatgacttcggcgcaggtggcgtgtccgtcgcagtcggcgaactcaccgacagc
atcgacatccacctcgatcgcgtaccactgaaatacgccggcctcaatgcccgcgaaatc
gccatctccgagtcccaggaacgcatggcagtcgtcgtgcgcccagaagacgcagccgcc
ttcattgaagcagccgcaaccgaaaacatcgaggctgtagagctcgccaccgtcaccgac
agcggacgcctgcgcatgttcctcggcgaagacgtagtcctcgacctctcccgcgaattc
ctcgaaaccaacggcgcagcacgctcccagagcgtagaaatgcgcgatgcaggagacgtc
gaaaagcctgctcagccggcaaccatcctcgaatccttgacccgccacggctcccaagaa
ggcatggtcgaacaattcgacgccaccgtcggacgctccaccgtactcatgccttacggc
ggccgcacccaaaaaaccgacgaactcgcatccgtacaaaccttcccagtaccaggcgga
tcccacaccgcatcggtcatgacctacggattcagcccagagcttgccgacgtctccccc
tacctcatgggctcctactccgtcgtcgaagcactcagccgactcgtcgccaccggtgcc
aacgcacgcggcgcatggctgtccgtccaagaatatttccagcgcctcgaccaaaaaccc
gaactctggggcgaagtaacccaggcactcctgggccttcttgaagcacaagacgccttc
gaagtagctgccatcggcggcaaggactccatgagcggcacctacggcgatgacctgcac
gttcccgcaacgctggtcaccttcgcagtcgcaaccatggacgcacgacgcaccctcagc
gccgccatcccaagcggcgaattcgacgtctaccacctcgcccacaccccgctggaaacc
ggcgaagccaactacgagcaactccgcgccaacttcgacgccttccatgagctcgccgcc
accggcaccctctcggcagcctcccccatcatcccaggagggctcggcgccaccatcgtg
aacatgctgctcggcaacgaactcggattccagggcaccgccaccaccaacgcagccctc
ggtggcctcgtattcgcggtcccagccggcaccgcagtcgagcttgccgacgcccaactc
atcggtcacaccaacccatccggcaagatcgccttcggcgaagaaaccttcaccatcgcc
caagcactcgacaccctagagcgcgactaccgcgaggtctaccccctcaacgtaaccacc
gcagacgtagaggccctcccagagtttgcgaccgccctacccacggcagactcggattct
gaagaagccaacgcctccgccggtgacaaagccgtacatgtgttgctgccagtatttcca
ggtactaactccgaatacgacatggcagaggccttcgacgcagcaggtgccaccactgaa
ttccacatcatccgaaacctcaactcggagatgctggctgctgacacagaagcattcatc
accaagctgcaatccgccaacatcttggcattctccggcggattctccctcggcgacgaa
ccagacggctcagcaaaattcatggcagccttcctacgctccgacgccgtagccgcagcg
gtcaaggacttcgtggctcgcgacggcctcgtcctcggtatctgcaacggcttccaagca
ctggtcaagagtggattcctgccatacggcgaccccgccaagatgaccgcagaatcccca
acgttggcacacaacctccaactgcgacacgtctcacgcatagccaccactcgcgtcagc
tccgtagcctccccatggctgagcaccttcaccccagaccagcagcacctcatgccggtt
tctcacggcgaaggccgcttcgtagtatccgaaacggaagcccaagcactgtttagcgca
ggtcaggtagcattccagtatgtggataccgagggcacccccaccatggaagcacctgcg
aaccccaacggatccaactatgccatcgagggcatcatctccccagatggtcgcatcctt
ggcaagatgggacaccccgagcgcttccgcgacggcctcatgcgcaacattcctggtatg
gaggtccaagacatcttcgctaacgcggtgaactactgccgtaagagtcaacactag
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