KEGG   Corynebacterium diphtheriae VA01: CDVA01_0719
Entry
CDVA01_0719       CDS       T01702                                 
Symbol
purH
Name
(GenBank) bifunctionalphosphoribosylaminoimidazolecarboxam ide formyltransferase/IMP cyclohydrolase
  KO
K00602  phosphoribosylaminoimidazolecarboxamide formyltransferase / IMP cyclohydrolase [EC:2.1.2.3 3.5.4.10]
Organism
cdv  Corynebacterium diphtheriae VA01
Pathway
cdv00230  Purine metabolism
cdv00670  One carbon pool by folate
cdv01100  Metabolic pathways
cdv01110  Biosynthesis of secondary metabolites
Module
cdv_M00048  De novo purine biosynthesis, PRPP + glutamine => IMP
Brite
KEGG Orthology (KO) [BR:cdv00001]
 09100 Metabolism
  09104 Nucleotide metabolism
   00230 Purine metabolism
    CDVA01_0719 (purH)
  09108 Metabolism of cofactors and vitamins
   00670 One carbon pool by folate
    CDVA01_0719 (purH)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04147 Exosome [BR:cdv04147]
    CDVA01_0719 (purH)
Enzymes [BR:cdv01000]
 2. Transferases
  2.1  Transferring one-carbon groups
   2.1.2  Hydroxymethyl-, formyl- and related transferases
    2.1.2.3  phosphoribosylaminoimidazolecarboxamide formyltransferase
     CDVA01_0719 (purH)
 3. Hydrolases
  3.5  Acting on carbon-nitrogen bonds, other than peptide bonds
   3.5.4  In cyclic amidines
    3.5.4.10  IMP cyclohydrolase
     CDVA01_0719 (purH)
Exosome [BR:cdv04147]
 Exosomal proteins
  Exosomal proteins of other body fluids (saliva and urine)
   CDVA01_0719 (purH)
SSDB
Motif
Pfam: AICARFT_IMPCHas MGS
Other DBs
NCBI-ProteinID: AEX82988
LinkDB
Position
759097..760674
AA seq 525 aa
MSDDRKQIKRALISVYDKTGLEDLARALNDAGVEIVSTGSTAAKIADLGVPVIPVEQLTG
FPECLEGRVKTLHPMVHAGILADTRKEDHLKQLDELNVAPFQLVVVNLYPFTQTVASGAD
FDACVEQIDIGGPSMVRAAAKNHPSIAVVVSPSRYSEIIAAVGNGGFTRAERTALAVDAF
RHTASYDVAVATWMGEQIADADEPFAEWIGASYELANILRYGENPHQAAALYTDPAAPAG
LAQATQLHGKEMSYNNYTDSDAAWRAAWDHERPCVAIIKHANPCGIAVSDVSIAEAHRTA
HACDPVSAFGGVIASNREVSVDMAKQVSEIFTEVIIAPSYEDGAVDILSQKKNIRILVAP
QPQRDELEQRQISGGVLVQRRDLVDAEGDNPANWILAAGEAASEELLAELEFAWRAVRAV
KSNAILLAQGGATVGVGMGQVNRVDAAKLAVERANSLAGDEQRAKGSVAASDAFFPFADG
LEVLAEAGVRAVVQPGGSIRDAEVIEAANKAGVTMYLTGARHFAH
NT seq 1578 nt   +upstreamnt  +downstreamnt
atgagtgatgaccgcaagcagatcaagcgcgcattaattagtgtgtacgacaagaccgga
ctggaagatctggcccgtgccctcaatgatgcgggtgtggagatcgtttccaccggctcg
accgccgctaaaatcgctgatctcggagtccctgtaattcccgtagagcaactcaccggc
ttcccagaatgtcttgaaggccgtgtgaagaccctacaccccatggttcacgcaggaatc
cttgctgacacgcgtaaggaggaccacctcaagcaactagacgagctcaacgtagcgccg
ttccagctcgtggtcgtcaacctgtacccatttacccagactgttgcctcgggtgccgat
ttcgacgcttgcgtcgagcagatcgacatcggaggaccatcgatggtccgtgctgcggct
aagaaccacccatcgatagcggtcgttgtatctccatctcgttactctgagatcatcgca
gcagttggcaacggtggcttcacccgcgctgagcgcacggctttggctgtcgacgctttc
cgccacaccgcttcttacgacgtcgccgtagcaacgtggatgggcgagcaaatcgcggac
gccgatgaaccattcgccgagtggatcggggctagctacgaactcgctaacatcctgcgt
tacggcgaaaacccacaccaagcggcggccctctacactgacccagcagctcctgctggc
cttgctcaagcaacgcagctacacggcaaggaaatgagctacaacaactacacggactcc
gacgcagcttggcgtgctgcatgggatcacgagcgcccatgcgtggccatcatcaagcac
gcaaacccctgcggtatcgcagtttccgacgtctccattgctgaagctcaccgcactgca
cacgcgtgtgacccagtctccgcatttggcggcgtgatcgcttccaaccgcgaagttagc
gtagatatggcgaagcaagtctccgaaatctttactgaggtcatcatcgccccttcctat
gaagatggtgcagtggacattctttcgcagaagaagaacatccgaatccttgtagctccg
cagccacagcgcgacgaactcgaacaacgccaaatctctggcggagttctggttcagcgc
cgcgatctcgttgatgctgaaggcgataacccagcaaactggatacttgctgccggtgaa
gctgcatctgaggaattgctggcagagctggaattcgcatggcgtgctgtccgtgctgtg
aagtccaatgccatcctgcttgcccaaggcggcgcaacagtaggcgtgggcatggggcag
gttaaccgtgtcgacgcagccaagcttgcagtagagcgcgctaattccctcgctggcgat
gaacagcgtgccaagggatcggttgcagcatctgatgcgttcttcccattcgctgacggc
ttagaggtgctggcagaagctggcgttcgtgctgtggttcagcctggtggatctatccgt
gatgctgaagtgatcgaggccgctaacaaggctggcgtgaccatgtacttgacgggtgcg
cgccacttcgctcactaa

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